메뉴 건너뛰기




Volumn 40, Issue 7, 1996, Pages 481-488

Hepatitis B virus with X gene mutation is associated with the majority of serologically "silent" non-B, non-C chronic hepatitis

Author keywords

HBV mutant; NBNC chronic hepatitis; X gene mutation

Indexed keywords

HEPATITIS B VIRUS;

EID: 0030345693     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.1996.tb01098.x     Document Type: Article
Times cited : (53)

References (39)
  • 1
    • 0025012035 scopus 로고
    • Chronic active hepatitis with hepatitis B virus DNA and antibody against e antigen in the serum. Disturbed synthesis and secretion of e antigen from hepatocytes due to a point mutation in the precore region
    • Akahane, Y., Yamanaka, T., Suzuki, H., Sugai, Y., Tsuda, F., Yotsumoto, S., Omi, S., Okamoto, H., Miyakawa, Y., and Mayumi, M. 1990. Chronic active hepatitis with hepatitis B virus DNA and antibody against e antigen in the serum. Disturbed synthesis and secretion of e antigen from hepatocytes due to a point mutation in the precore region. Gastroenterology 99: 1113-1119.
    • (1990) Gastroenterology , vol.99 , pp. 1113-1119
    • Akahane, Y.1    Yamanaka, T.2    Suzuki, H.3    Sugai, Y.4    Tsuda, F.5    Yotsumoto, S.6    Omi, S.7    Okamoto, H.8    Miyakawa, Y.9    Mayumi, M.10
  • 2
    • 0025190103 scopus 로고
    • The hepatitis B virus X-gene product trans-activates both RNA polymerase II and III promoters
    • Aufiero, B., and Schneider, J. 1990. The hepatitis B virus X-gene product trans-activates both RNA polymerase II and III promoters. EMBO J. 9: 497-504.
    • (1990) EMBO J. , vol.9 , pp. 497-504
    • Aufiero, B.1    Schneider, J.2
  • 5
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo, Q.L., Kuo, G., Weiner, A.J., Overby, L.R., Bradley, D.W., and Houghton, M. 1989. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244: 359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 6
    • 0028873905 scopus 로고
    • Analysis of the precore DNA sequence and detection of precore antigen in the liver specimens from patients with anti-hepatitis B e-positive chronic hepatitis
    • Diens, H.P., Gerken, G., Goergen, B., Heermann, K., Gerlich, W., and Büschen, K.H. 1995. Analysis of the precore DNA sequence and detection of precore antigen in the liver specimens from patients with anti-hepatitis B e-positive chronic hepatitis. Hepatology 21: 1-7.
    • (1995) Hepatology , vol.21 , pp. 1-7
    • Diens, H.P.1    Gerken, G.2    Goergen, B.3    Heermann, K.4    Gerlich, W.5    Büschen, K.H.6
  • 7
    • 0026343229 scopus 로고
    • Hepatitis B X open reading frame deletion mutants isolated from atypical hepatitis B virus infections
    • Feitelson, M., Duan, L.X., Horiike, N., and Clayton, M. 1991. Hepatitis B X open reading frame deletion mutants isolated from atypical hepatitis B virus infections. J. Hepatol. 13 (Suppl. 4): S58-S60.
    • (1991) J. Hepatol. , vol.13 , Issue.4 SUPPL.
    • Feitelson, M.1    Duan, L.X.2    Horiike, N.3    Clayton, M.4
  • 9
    • 0028900451 scopus 로고
    • Characterization of a functional hepatocyte nuclear factor 3 binding site in the hepatitis B virus nucleocapside promoter
    • Johnson, J.L., Raney, A.K., and Mclachla, A. 1995. Characterization of a functional hepatocyte nuclear factor 3 binding site in the hepatitis B virus nucleocapside promoter. Virology 208: 147-158.
    • (1995) Virology , vol.208 , pp. 147-158
    • Johnson, J.L.1    Raney, A.K.2    Mclachla, A.3
  • 11
    • 0028031979 scopus 로고
    • Repression of enhancer II activity by a negative regulatory element in the hepatitis B virus genome
    • Lo, W.Y., and Ting, L.P. 1994. Repression of enhancer II activity by a negative regulatory element in the hepatitis B virus genome. J. Virol. 68: 1758-1764.
    • (1994) J. Virol. , vol.68 , pp. 1758-1764
    • Lo, W.Y.1    Ting, L.P.2
  • 12
    • 0025280390 scopus 로고
    • Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: Trans-activation and repression by CCAT/enhancer binding protein
    • Lopez-Cabrera, M., Letovsky, J., Hu, K.Q., and Siddiqui, A. 1990. Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: trans-activation and repression by CCAT/enhancer binding protein. Proc. Natl. Acad. Sci. U.S.A. 87: 5069-5073.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 5069-5073
    • Lopez-Cabrera, M.1    Letovsky, J.2    Hu, K.Q.3    Siddiqui, A.4
  • 13
    • 0025875751 scopus 로고
    • Transcriptional factor C/EBP binds to and transactivates the enhancer element II of the hepatitis B virus
    • Lopez-Cabrera, M., Letovsky, J., Hu, K.Q., and Siddiqui, A. 1991. Transcriptional factor C/EBP binds to and transactivates the enhancer element II of the hepatitis B virus. Virology 183: 825-829.
    • (1991) Virology , vol.183 , pp. 825-829
    • Lopez-Cabrera, M.1    Letovsky, J.2    Hu, K.Q.3    Siddiqui, A.4
  • 14
    • 0025784335 scopus 로고
    • HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions
    • Maguire, H.F., Hoeffler, J.P., and Siddiqui, A. 1991. HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions. Science 252: 842-844.
    • (1991) Science , vol.252 , pp. 842-844
    • Maguire, H.F.1    Hoeffler, J.P.2    Siddiqui, A.3
  • 15
    • 0025098335 scopus 로고
    • Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: Application to diagnosis and blood screening for posttransfusion hepatitis
    • Miyamura, T., Saito, I., Katayama, T., Kikuchi, S., Takeda, A., Houghton, M., and Choo, Q.L. 1990. Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: application to diagnosis and blood screening for posttransfusion hepatitis. Proc. Natl. Acad. Sci. U.S.A. 87: 983-987.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 983-987
    • Miyamura, T.1    Saito, I.2    Katayama, T.3    Kikuchi, S.4    Takeda, A.5    Houghton, M.6    Choo, Q.L.7
  • 16
    • 0027971962 scopus 로고
    • Hepatitis may precede the occurrence of precore region mutation in hepatitis B virus genome during infection in young carriers
    • Nguyen, T.X., Fukuda, R., and Fukumoto, S. 1994. Hepatitis may precede the occurrence of precore region mutation in hepatitis B virus genome during infection in young carriers. J. Med. Virol. 44: 200-205.
    • (1994) J. Med. Virol. , vol.44 , pp. 200-205
    • Nguyen, T.X.1    Fukuda, R.2    Fukumoto, S.3
  • 17
    • 0028105910 scopus 로고
    • Precore region mutation in hepatitis B virus genome: A study in hepatitis e antigen positive young carriers
    • Nguyen, T.X., Fukuda, R., and Fukumoto, S. 1994. Precore region mutation in hepatitis B virus genome: a study in hepatitis e antigen positive young carriers. J. Gastroenterol. 20: 469-473.
    • (1994) J. Gastroenterol. , vol.20 , pp. 469-473
    • Nguyen, T.X.1    Fukuda, R.2    Fukumoto, S.3
  • 18
    • 0025200429 scopus 로고
    • Detection of hepatitis C virus by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5′-non coding region
    • Okamoto, H., Mochida, S., Suematsu, Y., Tanaka, T., Sugai, Y., Akahane, Y., Machida, A., and Mayumi, M. 1990. Detection of hepatitis C virus by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5′-non coding region. Jpn. J. Exp. Med. 60: 215-222.
    • (1990) Jpn. J. Exp. Med. , vol.60 , pp. 215-222
    • Okamoto, H.1    Mochida, S.2    Suematsu, Y.3    Tanaka, T.4    Sugai, Y.5    Akahane, Y.6    Machida, A.7    Mayumi, M.8
  • 19
    • 2842514483 scopus 로고
    • Functional similarities between human immunodeficiency virus type I and simian virus 40 kB proto-enhancers
    • Phares, M., and Herr, W. 1991. Functional similarities between human immunodeficiency virus type I and simian virus 40 kB proto-enhancers. J. Virol. 65: 825-829.
    • (1991) J. Virol. , vol.65 , pp. 825-829
    • Phares, M.1    Herr, W.2
  • 21
    • 0026438381 scopus 로고
    • Detection of a hepatitis B virus variant with a truncated X gene and enhancer II
    • Repp, R., Keller, C., Borkhardt, A., and Csecke, A. 1992. Detection of a hepatitis B virus variant with a truncated X gene and enhancer II. Arch. Virol. 125: 299-304.
    • (1992) Arch. Virol. , vol.125 , pp. 299-304
    • Repp, R.1    Keller, C.2    Borkhardt, A.3    Csecke, A.4
  • 22
    • 0025802779 scopus 로고
    • An internal domain of the hepatitis B virus X antigen is necessary for transactivity
    • Ritter, S.E., Whitten, T.M., Quets, A.T., and Schloemer, R.H. 1991. An internal domain of the hepatitis B virus X antigen is necessary for transactivity. Virology 182: 841-845.
    • (1991) Virology , vol.182 , pp. 841-845
    • Ritter, S.E.1    Whitten, T.M.2    Quets, A.T.3    Schloemer, R.H.4
  • 23
    • 0026514186 scopus 로고
    • Review: Hepatitis B virus X-gene product: a promiscuous transcriptional activator
    • Rossner, M.T. 1992. Review: hepatitis B virus X-gene product: a promiscuous transcriptional activator. J. Med. Virol. 36: 101-117.
    • (1992) J. Med. Virol. , vol.36 , pp. 101-117
    • Rossner, M.T.1
  • 24
    • 0020600534 scopus 로고
    • Detection of hepatitis B virus in serum by a simple spot hybridization technique: Comparison with results for other viral markers
    • Scotte, J., Hadchouel, M., Hery, C., Yvart, J., and Brechot, C. 1983. Detection of hepatitis B virus in serum by a simple spot hybridization technique: comparison with results for other viral markers. Hepatology 3: 279-284.
    • (1983) Hepatology , vol.3 , pp. 279-284
    • Scotte, J.1    Hadchouel, M.2    Hery, C.3    Yvart, J.4    Brechot, C.5
  • 25
    • 0022502287 scopus 로고
    • Biochemical and genetic evidences for the hepatitis B virus replication strategy
    • Seeger, C., Ganem, D., and Varmus, H.E 1986. Biochemical and genetic evidences for the hepatitis B virus replication strategy. Science 232: 477-484.
    • (1986) Science , vol.232 , pp. 477-484
    • Seeger, C.1    Ganem, D.2    Varmus, H.E.3
  • 28
    • 0023833938 scopus 로고
    • Trans-activation of viral enhancers by the hepatitis B virus X protein
    • Spandau, D.F., and Lee, C.H. 1988. Trans-activation of viral enhancers by the hepatitis B virus X protein. J. Virol. 62: 427-434.
    • (1988) J. Virol. , vol.62 , pp. 427-434
    • Spandau, D.F.1    Lee, C.H.2
  • 29
    • 0025719635 scopus 로고
    • Mutational analysis of two herpes simplex virus type I late promoters
    • Steffy, K., and Weir, J.P. 1991. Mutational analysis of two herpes simplex virus type I late promoters. J. Virol. 65: 6454-6460.
    • (1991) J. Virol. , vol.65 , pp. 6454-6460
    • Steffy, K.1    Weir, J.P.2
  • 30
    • 0025635770 scopus 로고
    • X protein of hepatitis B virus resembles a serine protease inhibitor
    • Takada, S., and Koike, K. 1990. X protein of hepatitis B virus resembles a serine protease inhibitor. Jpn. J. Cancer Res. 81: 1191-1194.
    • (1990) Jpn. J. Cancer Res. , vol.81 , pp. 1191-1194
    • Takada, S.1    Koike, K.2
  • 31
    • 0027283915 scopus 로고
    • Genetic variations of the hepatitis B virus and their clinical relevance
    • Uchida, T. 1993. Genetic variations of the hepatitis B virus and their clinical relevance. Microbiol. Immunol. 37: 425-439.
    • (1993) Microbiol. Immunol. , vol.37 , pp. 425-439
    • Uchida, T.1
  • 32
    • 0027973689 scopus 로고
    • Pathology of liver infected with "silent" hepatitis B virus mutant
    • Uchida, T., Shimojima, S., Gotoh, K., Shikata, T., and Mima, S. 1994. Pathology of liver infected with "silent" hepatitis B virus mutant. Liver 14: 251-256.
    • (1994) Liver , vol.14 , pp. 251-256
    • Uchida, T.1    Shimojima, S.2    Gotoh, K.3    Shikata, T.4    Mima, S.5
  • 33
    • 0028175488 scopus 로고
    • "Silent" hepatitis B virus mutants are responsible for Non-A, Non-B, Non-C, Non-D, Non-E hepatitis
    • Uchida, T., Shimojima, M., Gotoh, K., Shikata, T., Tanaka, E., and Kiyosawa, K. 1994. "Silent" hepatitis B virus mutants are responsible for Non-A, Non-B, Non-C, Non-D, Non-E hepatitis. Microbiol. Immunol. 38: 281-285.
    • (1994) Microbiol. Immunol. , vol.38 , pp. 281-285
    • Uchida, T.1    Shimojima, M.2    Gotoh, K.3    Shikata, T.4    Tanaka, E.5    Kiyosawa, K.6
  • 34
    • 0028943229 scopus 로고
    • Complete nucleotide sequence and characteristics of two HBV mutants causing serologically negative acute or chronic hepatitis B
    • Uchida, T., Gotoh, K., and Shikata, T. 1995. Complete nucleotide sequence and characteristics of two HBV mutants causing serologically negative acute or chronic hepatitis B. J. Med. Virol. 45: 247-252.
    • (1995) J. Med. Virol. , vol.45 , pp. 247-252
    • Uchida, T.1    Gotoh, K.2    Shikata, T.3
  • 35
    • 0025299483 scopus 로고
    • The X protein of the hepatitis B virus acts as a transcriptional factor when targeted to its responsive elements
    • Unger, T., and Shaul, Y. 1990. The X protein of the hepatitis B virus acts as a transcriptional factor when targeted to its responsive elements. EMBO J. 9: 1889-1895.
    • (1990) EMBO J. , vol.9 , pp. 1889-1895
    • Unger, T.1    Shaul, Y.2
  • 36
    • 0025279853 scopus 로고
    • A new enhancer element, ENII, identified in the X gene of hepatitis B virus
    • Wang, Y., Chen, P., Wu, S., Sun, A.L., Wang, H., Zhu, Y.A., and Li, Z.P. 1990. A new enhancer element, ENII, identified in the X gene of hepatitis B virus. J. Virol. 64: 3977-3981.
    • (1990) J. Virol. , vol.64 , pp. 3977-3981
    • Wang, Y.1    Chen, P.2    Wu, S.3    Sun, A.L.4    Wang, H.5    Zhu, Y.A.6    Li, Z.P.7
  • 37
    • 0024468844 scopus 로고
    • A liver-specific enhancer in the core promoter region of human hepatitis B virus
    • Yee, J.K. 1989. A liver-specific enhancer in the core promoter region of human hepatitis B virus. Science 246: 658-661.
    • (1989) Science , vol.246 , pp. 658-661
    • Yee, J.K.1
  • 38
    • 0026635529 scopus 로고
    • Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus
    • Yuh, C., Chang, Y.L., and Ting, L.P. 1992. Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus. J. Virol. 66: 4073-4084.
    • (1992) J. Virol. , vol.66 , pp. 4073-4084
    • Yuh, C.1    Chang, Y.L.2    Ting, L.P.3
  • 39
    • 0028013064 scopus 로고
    • Woodchuck hepatitis virus X protein is required for viral infection in vivo
    • Zoulim, F., Saputelli J., and Seeger, C. 1994. Woodchuck hepatitis virus X protein is required for viral infection in vivo. J. Virol. 68: 2026-2030.
    • (1994) J. Virol. , vol.68 , pp. 2026-2030
    • Zoulim, F.1    Saputelli, J.2    Seeger, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.