Detection of Antibodies to Melanocytes in Vitiligo by Western Immunoblotting

Yonsei Medical Journal

Volumn 37, Issue 6, 1996, Pages 365-370

  Hann, Seung Kyung ^a   Shin, Hang Kye ^a   Park, Sang Hoon ^a   Reynolds, Sandra R ^b   Bystryn, Jean Claude ^b  

^a Yonsei University College of Medicine   (South Korea)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Autoimmunity; Melanocyte antibody; Vitiligo; Western blot

Indexed keywords

ANTIBODY; ANTIGEN;

ARTICLE; HUMAN; IMMUNOLOGY; MELANOCYTE; PATHOLOGY; REFERENCE VALUE; VITILIGO; WESTERN BLOTTING;

ANTIBODIES; ANTIGENS; BLOTTING, WESTERN; HUMANS; MELANOCYTES; REFERENCE VALUES; VITILIGO;

EID: 0030342131     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.1996.37.6.365     Document Type: Article

References (14)

1. Austin LM, Boissu RE, Jacobson BS, Smyth JR Jr: The detection of melanocyte autoantibodies in the Smyth chicken model for vitiligo. Clin Immunol Immunopathol 62: 112-120, 1992
2. Bystryn JC, Naughton GK: The significance of vitiligo antibodies. J Dermatol 12: 1-9, 1985
3. Cui J, Arita Y, Bystryn JC: Characterization of vitiligo antigens. Pigment Cell Res 8: 53-59, 1995
4. Cui J, Harning R, Heen M, Bystryn JC: Identification of pigment cell antigens defined by vitiligo antibodies. J Invest Dermatol 98: 163-165, 1992
5. Gilchrest BA, Vrabel MA, Flynn E, Szabo G: Selective cultivation of human melanocytes from newborn and adult epidermis. J Invest Dermatol 83: 370-376, 1984
6. Harning R, Cui J, Bystryn JC: Relation between the incidence and level of pigment cell antibodies and disease activity in vitiligo. J Invest Dermatol 97: 1078-1080, 1991
7. Koga M: Vitiligo: A new classification and therapy. Br J Dermatol 97: 255-261, 1977
8. Naughton GK, Eisinger M, Bystryn JC: Antibodies to normal human melanocytes in vitiligo. J Exp Med 158: 246-251, 1982
9. Naughton GK, Eisinger M, Bystryn JC: Detection of antibodies to melanocytes in vitiligo by specific immunoprecipitation. J Invest Dermatol 81: 540-542, 1983
10. Naughton GK, Mhaffey M, Bystryn JC: Antibodies surface antigens of pigmented cells in animals with vitiligo. Proc Soc Exp Biol Med 181: 423-426, 1986a
11. Naughton GK, Reaggiardo D, Bystryn JC: Correlation between vitiligo antibodies and extent of depigmentation in vitiligo. J Am Acad Dermatol 15: 978-981, 1986b
12. Norris DA, Kissinger RM, Naughton GK, Bystryn JC: Evidence for immunologic mechanisms in human vitiligo: Patients' sera induce damage to human melanocytes in vitro by complement-mediated damage and antibody dependent cellular cytotoxicity(ADCC). J Invest Dermatol 90: 783-789, 1988
13. Park YK, Kim NS, Hann SK, Im S: Identification of autoantibody to melanocytes and characterization of vitiligo antigens in vitiligo patients. J Dermatol Sci 11: 111-120, 1996
14. Song YH, Conor E, Li Y, Zorovich B, Balcuddi P, Anclaren N: The role of tyrosinase in autoimmune vitiligo. Lancet 344: 1049-1052, 1994