The measurement of molecular diversity: A three-dimensional approach

Journal of Computer-Aided Molecular Design

Volumn 10, Issue 6, 1996, Pages 501-512

  Chapman, David ^a  

^a Afferent Corp   (United States)

Author keywords

Combinatorial chemistry; Library screening; Ligand protein binding; Molecular shape; Molecular similarity; Scoring function

Indexed keywords

BIOCHEMISTRY; BIOCHIPS; CARBOXYLATION; CHAINS; LIGANDS; PROTEINS;

COMBINATORIAL CHEMISTRY; HIGH THROUGHPUT SCREENING; LIBRARY SCREENING; LIGAND-PROTEIN BINDING; MEASUREMENTS OF; MOLECULAR DIVERSITY; MOLECULAR SHAPES; MOLECULAR SIMILARITY; SCORING FUNCTIONS; SIDE-CHAINS;

LIBRARIES;

AMINO ACID; CARBOXYLIC ACID; LIGAND; POLYAMINE;

ALGORITHM; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER AIDED DESIGN; DRUG DESIGN; DRUG SCREENING; ENTROPY; EVALUATION; PHYSICAL CHEMISTRY;

ALGORITHMS; AMINO ACIDS; CARBOXYLIC ACIDS; CHEMISTRY, PHYSICAL; COMPUTER-AIDED DESIGN; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENTROPY; EVALUATION STUDIES; LIGANDS; MOLECULAR STRUCTURE; POLYAMINES;

EID: 0030341922     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00134174     Document Type: Article

References (2)

1. a. Gallop, M.A., Barret, R.W., Dower, W.J., Fodor, S.P.A. and Gordon, E.M., J. Med. Chem., 37 (1994) 1233.
2. b. Gordon, E.M., Barret, R.W., Dower, W.J., Fodor, S.P.A. and Gallop, M.A., J. Med. Chem., 37 (1994) 1386.