Tryptophan starvation is involved in human interferon-gamma mediated apoptosis

Advances in Experimental Medicine and Biology

Volumn 398, Issue , 1996, Pages 155-159

  Taylor, M W ^a   Konan, V K ^a   Yu, D ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIMYCIN; DNA; GAMMA INTERFERON; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CELL LINE; CELL STRAIN HL 60; DRUG EFFECT; HUMAN; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CALCIMYCIN; CELL LINE; DNA; EIF-2 KINASE; ELECTROPHORESIS, AGAR GEL; HL-60 CELLS; HUMANS; INTERFERON TYPE II; KINETICS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TRYPTOPHAN; TRYPTOPHAN OXYGENASE;

EID: 0030340445     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4613-0381-7_25     Document Type: Article

References (16)

1. Aune, T.M., and Pogue, S.L., 1989, Inhibition of tumor cell growth by interferon gamma is mediated by two distinct mechanism dependent upon oxygen tension: induction of tryptophan degradation in vitro and depletion of intracellular nicotinamide adenine dinucleotide. J. Clinical Invest. 84:863.
2. Carlin, J.M., Borden, E.C., Sondel, P.M. and Byrne, G.I., 1987, Biological Response modifier-induced indoleamine 2,3 dioxygenase activity in human peripheral blood mononuclear cell cultures. J. Immunol. 139:2414.
3. Chen, M., Quintans, J., Fuks, Z., Thompson, C., Kufe, D.W., and Weichselbaum, R.R., 1995, Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor -a, and ceramide. Cancer Research 55:991.
4. Chong, K.L., Feng, L., Schappert, K., Meurs, E., Donahue, T.F., Freisen, D.J., Havanessian, A.G., and Williams, B.R., 1992, Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2. EMBO-J., 11:1553.
5. Feng, G., and Taylor, M.W., 1989, Interferon-γ resistant mutants are defective in the induction of indoleamine 2,3 dioxygenase. Proc. Natl. Acad. Sci. USA 86:7144
6. Lee, S.B., and Esteban, M., 1994, The interferon induced double-stranded RNA activated protein kinase induces apoptosis. Virology 199:491.
7. McCormack, S.J., Ortega, L.G., Doohan, J.P., and Samuel, C.E., 1994, Mechanisms of interferon action motif I of the interferon induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity. Virology, 198:92.
8. Muschel, R.J., Bernhard, E.J., Garza, L., McKenna, W.G., and Koch, C.J., 1995, Induction of apoptosis at different oxygen tensions. Evidence that oxygen radicals do not mediate apoptotic signaling. Cancer Research, 55:995.
9. Ozaki, Y., Edelstein, M.P., and Duch, D.S., 1988, Induction of indoleamine 2,3 dioxygenase: a mechanism of the antitumor activity of interferon-γ. Proc. Nat. Acad. Sci USA 85:1242.
10. Ozes, O.N., and Taylor, M.W., 1993, Reversal of IFN-γ resistant phenotype by polyI:C. Possible involvement of double stranded RNA activated kinase in IFN-γ mediated induction of the IDO gene. J. Interferon Research. 13:283
11. Samuel, C.E., 1993, The eIF-2 alpha protein kinases, regulators of translation in eukaryotes and yeasts to humans. J. Biol. Chem. 268:7603.
12. Taylor, M.W., and Feng, G., 1991, relationship between interferon-γ, indoleamine 2,3 dioxygenase and tryptophan catabolism. FASEB J. 5:2516.
13. Wagner, A.J., Small, M.B., and Hay, N., 1993, Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2. Mol. Cell Biol. 13:2432.
14. Yoshida, R., and Hayaishi, O., 1978, Induction of pulmonary indoleamine 2,3 dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide. Proc. Nat. Acad. Sci. USA 75:3998.
15. Yoshida, R., Urade, Y., Tokuda, M., and Hayaishi, O., 1979, Induction of indoleamine 2,3 dioxygenase in mouse lung during virus infection. Proc. Nat. Acad. Sci. USA 76:4084..
16. Yonish-Rouach, E. Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., and Oren, M., 1991, Wild type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 352:345.