Phosphorylation and activation of smooth Muscle Myosin Light Chain Kinase by MAP kinase and cyclin-dependent kinase-1

Biochemistry and Cell Biology

Volumn 74, Issue 4, 1996, Pages 549-557

  Morrison, Donna L ^a   Sanghera, Jasbinder S ^a   Stewart, Justine ^a   Sutherland, Cindy ^b   Walsh, Michael P ^b   Pelech, Steven L ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c Kinetek Pharmaceuticals Inc   (Canada)

Author keywords

Cyclin dependent kinase; Mitogen activated protein kinase; Myosin light chain kinase

Indexed keywords

CALMODULIN; CYCLIN DEPENDENT KINASE 1; MYOSIN LIGHT CHAIN KINASE; PEPTIDE FRAGMENT; PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTRANSFERASE; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL; ARTICLE; BINDING SITE; CHEMISTRY; CHICKEN; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; SMOOTH MUSCLE;

ANIMALS; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN; CDC2 PROTEIN KINASE; CHICKENS; ENZYME ACTIVATION; MUSCLE, SMOOTH; MYOSIN-LIGHT-CHAIN KINASE; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTRANSFERASES;

EID: 0030340292     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o96-459     Document Type: Article

References (36)

1. Alvarez, E., Northwood, I.C., Gonzalez, F.A., Latour, D.A., Seth, A., Abate, C., Curran, T., and Davis, R.J. 1991. Pro-Leu-Ser/Thr-Pro is a consensus sequence for substrate protein phosphorylation. J. Biol. Chem. 266: 15 277-15 285.
2. Baraban, J.M., Fiore, R.S., Sanghera, J.S., Paddon, H.B., and Pelech, S.L. 1993. Identification of p42 MAP kinase as a tyrosine kinase substrate activated by electroconvulsive treatment in hippocampus. J. Neurochem. 60: 330-336.
3. Bogoyevitch, M.A., Glennon, P.E., Andersson, M.B., Clerk, A., Lazou, A., Marshall, C.J., Parker, P.J., and Sugden, P.H. 1994. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways. J. Biol. Chem. 269: 1110-1119.
4. Childs, T., Watson, M.H., Sanghera, J.S., Campbell, D.L., Pelech, S.L., and Mak, A.S. 1992. Phosphorylation of smooth muscle caldesmon by MAP kinase and expression of MAP kinase in differentiated smooth muscle cells. J. Biol. Chem. 276: 22 853-22 859.
5. mpk, the meiosis-activated myelin basic protein kinase. J. Biol. Chem. 266: 15 180-15 184.
6. Conti, M.A., and Adelstein, R.S. 1981. The relationship between calmodulin binding and phosphorylation of smooth muscle myosin kinase by the catalytic subunit of 3′:5′-cyclic-AMP-dependent protein kinase. J. Biol. Chem. 256: 3178-3181.
7. Foster, C.J., Johnston, S.A., Sunday, B., and Gaeta, F.C.A. 1990. Potent peptide inhibitors of smooth muscle myosin light chain kinase: mapping of the pseudosubstrate and calmodulin binding domains. Arch. Biochem. Biophys. 280: 397-404.
8. 2+/calmodulin-dependent multifunctional protein kinase-II. Comparative study of phosphorylation sites. Arch. Biochem. Biophys. 278: 41-45.
9. Hei, Y.-J., McNeill, J.H., Sanghera, J.S., Diamond, J., Bryer-Ash, M., and Pelech, S.L. 1993. Activation of MAP kinases and S6 kinases in rat skeletal muscle by in vivo administration of insulin. J. Biol. Chem. 268: 13 203-13 213.
10. Hosoya, H., Yamashiro, S., and Matsumura, F. 1991. Mitosis-specific phosphorylation of myosin light chain kinase. J. Biol. Chem. 266: 22 173-22 178.
11. 2+/calmodulin-dependent multifunctional protein kinase. J. Biol. Chem. 265: 8975-8978.
12. 2+-activated, phospholipid-dependent protein kinase. J. Biol. Chem. 260: 4547-4550.
13. Ikebe, M., Inagaki, M., Naka, M., and Hidaka, H. 1988. Correlation of conformation and phosphorylation and dephosphorylation of smooth muscle myosin. J. Biol. Chem. 263: 10 698-10 704.
14. Kemp, B.E., and Pearson, R.B. 1985. Spatial requirements for location of basic residues in peptide substrates for smooth muscle myosin light chain kinase. J. Biol. Chem. 260: 3355-3359.
15. Kennelly, P.J., and Krebs, E.G. 1991. Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases. J. Biol. Chem. 266: 15 555-15 558.
16. Labbe, J.-C., Capony, J.-C., Caput, D., Cavadore, J.-C., Derancourt, J., Kaghad, M., Lelias, J.-M., Picard, A., and Doree, M. 1989. MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B. EMBO J. 8: 3053-3058.
17. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London), 227: 680-684.
18. cdc2. J. Biol. Chem. 266: 2557-2566.
19. Lukas, T.J., Burgess, W.H., Prendergast, F.G., Lau, W., and Watterson, D.M. 1986. Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase. Biochemistry, 25: 1458-1464.
20. cdc2: in vivo veritas? Cell, 64: 549-551.
21. Mukhopadhyay, N.K., Price, D.J., Kyriakis, J.M., Pelech, S., Sanghera, J., and Avruch, J. 1992. An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase. J. Biol. Chem. 267: 3325-3335.
22. Ngai, P.K., Carruthers, C.A., and Walsh, M.P. 1984. Isolation of the native form of chicken gizzard mylosin light chain kinase. Biochem. J. 218: 863-870.
23. Nishikawa, M., de Lanerolle, P., Lincoln, T.M., and Adelstein, R.S. 1984. Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic-AMP-dependent protein kinase and by cyclic-GMP-dependent protein kinase. J. Biol. Chem. 259: 8429-8436.
24. Nishikawa, M., Shirakawa, S., and Adelstein, R.S. 1985. Phosphorylation of smooth muscle myosin light chain kinase by protein kinase C. Comparative study of the phosphorylation sites. J. Biol. Chem. 260: 8978-8983.
25. Olson, N.J., Pearson, R.B., Needleman, D.S., Hurwitz, M.Y., Kemp, B.E., and Means, A.R. 1990. Regulatory and structural motifs of chicken gizzard myosin light chain kinase. Proc. Natl. Acad. Sci. U.S.A. 87: 2284-2288.
26. Payne, E.M., Elzinga, M., and Adelstein, R.S. 1986. Smooth muscle myosin light chain kinase. Amino acid sequence at the site phosphorylated by adenosine 3′:5′-phosphate-dependent protein kinase whether or not calmodulin is bound. J. Biol. Chem. 261: 16 346-16 350.
27. Pelech, S.L. 1995. Networking with proline-directed protein kinases implicated in tau phosphorylation. Neurobiol. Aging, 16: 347-361.
28. Pelech, S.L., and Charest, D.L. 1995. MAP kinase-dependent pathways in cell cycle control. In Progress in cell cycle research. Vol. 1. Edited by L. Meijer, S. Guidet, and L. Tung. Plenum Press, New York. pp. 33-52.
29. Pelech, S.L., Tombes, R.M., Meijer, L., and Krebs, E.G. 1988. Activation of myelin basic protein kinases during echinoderm oocyte maturation and egg fertilization. Dev. Biol. 130: 28-36.
30. Persechini, A., and Hartshome, D.J. 1981. Phosphorylation of smooth muscle myosin: evidence for cooperativity between the myosin heads. Science (Washington, D.C.), 213: 1383-1385.
31. Sanghera, J.S., Paddon, H.B., Bader, S.A., and Pelech, S.L. 1990. Purification and characterization of a maturation-activated myelin basic protein kinase from sea star ocytes. J. Biol. Chem. 265: 52-57.
32. 2+ desensitization. Mol. Cell. Biochem. 127/ 128: 229-237.
33. Walsh, M.P. 1991. The Ayerst Award Lecture 1990. Calcium-dependent mechanisms of regulation of smooth muscle contraction. Biochem. Cell Biol. 69: 771-800.
34. Walsh, M.P., Hinkins, S., Dabrowska, R., and Hartshorne, D.J. 1983. Smooth muscle myosin light chain kinase. Methods Enzymol. 99: 279-288.
35. 2+-binding protein and protein kinase C from bovine brain. Biochem. J. 224: 117-127.
36. Yamazaki, T., Tobe, K., Hoh, E., Maemura, K., Kaida, T., Komuro, I., Tamemoto, H., Kadowaki, T., Nagai, R., and Yazaki, Y. 1993. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J. Biol. Chem. 268: 12 069-12 076.