Neurotrophic factors as pharmacological agents for the treatment of injured auditory neurons

CIBA Foundation Symposia

Volumn , Issue 196, 1996, Pages 149-166

  Van De Water, Thomas R ^a,b   Staecker, Hinrich ^a,b   Ernfors, Patrik ^c   Moonen, Gustave ^b   Lefebvre, Philippe P ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; NERVE PROTEIN;

ANIMAL; COCHLEA; CYTOLOGY; DRUG EFFECT; HUMAN; METABOLISM; NERVE CELL; NERVE DEGENERATION; PHYSIOLOGY; REVIEW; VESTIBULOCOCHLEAR NERVE;

ANIMALS; COCHLEA; HUMANS; NERVE DEGENERATION; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; VESTIBULOCOCHLEAR NERVE;

EID: 0030339863     PISSN: 03005208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Ard M, Morest D, Haugher S 1985 Trophic interactions between the cochleovestibular ganglion of the chick embryo and its synaptic targets in culture. Neuroscience 16: 151-170
2. Avila M, Varela-Nieto I, Romero G, Mato J, Van De Water TR, Represa J 1993 Brain derived neurotrophic factor and neurotrophin-3 support the survival and neuritogenesis response of developing cochleovestibular ganglion neurons. Dev Biol 159: 266-275
3. Berglund AM, Ryugo DK 1987 Hair cell innervation by spiral ganglion neurons in the mouse. J Comp Neurol 255:560-570
4. Brown JN, Miller JM, Atlschuler RA, Nutall AL 1993 Osmotic pump implant for chronic infusion of drugs into the inner ear. Hear Res 70:167-172
5. Corwin JT, Cotanche DA 1989 Development of localization-specific hair cell stereocilia in denervated embryonic ears. J Comp Neurol 288:529-537
6. D'Amico-Martel A, Noden D 1983 Contributions of placodal and neural crest cells to avian cranial peripheral ganglia. Am J Anat 166:445-468
7. Ernfors P, Merlio J-P, Persson H 1992 Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development. Eur J Neurosci 4:1140-1158
8. Ernfors P, Van De Water TR, Loring J, Jaenisch R 1995 Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 14:1153-1164
9. Farinas I, Jones KR, Backus C, Wang X-Y, Reichardt LF 1994 Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature 369:658-661
10. Federoff HJ, Geschwind MD, Geller AI, Kessler JA 1992 Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia. Proc Natl Acad Sci USA 89:1636-1640
11. Geschwind MD, Kessler JA, Geller AI, Federoff HJ 1994 Transfer of the nerve growth factor gene into cell lines and cultured neurons using a defective herpes simplex virus vector - transfer of the NGF gene into cells by a HSV-1 vector. Mol Brain Res 24:327-335
12. Geschwind MD, Hartnick CJ, Liu W, Amat J, Van De Water TR, Federoff HJ 1996 Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neurite outgrowth: model for treatment of neuron loss following cochlear degeneration. Hum Gene Ther, in press
13. Hirokawa N 1977 Disappearance of afferent and efferent nerve terminals in the inner ear of the chick embryo after chronic treatment with beta-bungarotoxin. J Cell Biol 73:27-46
14. Lefebvre PP, Van De Water TR, Represa J et al 1991a Temporal pattern of nerve growth factor (NGF) binding in-vivo and the in-vitro effects of NGF on cultures of developing auditory and vestibular neurons. Acta Oto-laryngol 111:304-311
15. Lefebvre PP, Van De Water TR, Weber T, Register B, Moonen G 1991b Growth factor interactions in cultures of dissociated adult acoustic ganglia: neuronotrophic effects. Brain Res 567:306-312
16. 1 modulates bFGF receptor message expression in cultured adult auditory neurons. NeuroReport 2:305-308
17. Lefebvre PP, Van De Water TR, Staecker H et al 1992a Nerve growth factor stimulates neurite regeneration but not survival of adult auditory neurons in-vitro. Acta Otolaryngol 112:288-293
18. 1 expression is initiated in adult auditory neurons by sectioning of the auditory nerve. NeuroReport 3:295-298
19. Lefebvre PP, Malgrange B, Staecker H, Moghadassi M, Van De Water TR, Moonen G 1994 Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro. NeuroReport 5:865-868
20. Lenoir M, Shnerson A, Pujol R 1980 Cochlear receptor development in the rat with emphasis on synaptogenesis. Anat Embryol 160:253-262
21. Luo L, Coutnouyan H, Baird A, Ryan A 1993 Acidic and basic FGF mRNA expression in the adult and developing rat cochlea. Hear Res 69:182-193
22. Pirvola U, Ylikoski J, Palgi J, Lehtonen E, Arumae U, Saarma M 1992 Brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the peripheral target fields of developing inner ear ganglia. Proc Natl Acad Sci USA 89:9915-9919
23. Pirvola U, Arumae U, Moshnyakov M, Palgi U, Saarma M, Ylikoski J 1994 Coordinated expression and function of neurotrophins and their receptors in the rat inner ear during target innervation. Hear Res 75:131-144
24. Rueda J, De la Sen C, Juiz J, Merchan JA 1987 Neuronal loss in the spiral ganglion of young rats. Arch Otolaryngol 104:417-421
25. Spoendlin H 1988 Biology of the vestibulocochlear nerve. In: Albert PW, Ruben RJ (eds) Otologic medicine and surgery, vol 1. Churchill Livingstone, New York, p 117-150
26. Staecker H, Liu W, Hartnick C et al 1995a NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants. NeuroReport 6:1533-1537
27. Staecker H, Kopke R, Lefebvrc PP, Malgrange B, Liu W, Moonen G, Van De Water TR 1995b The effects of neurotrophins on adult auditory neurons in vitro and in vivo. Assoc Res Otolaryngol Abstr #705, p 177
28. Van De Water TR 1976 Effects of removal of the statoacoustic ganglion complex upon the growing otocyst. Ann Otol Rhinol & Laryngol (suppl 33) 85:1-32
29. Vasquez E, Van De Water TR, Del Valle M et al 1994 Pattern of trkB protein-like immunoreactivity in-vivo and the in-vitro effects of brain-derived neurotrophic factor (BDNF) on developing cochlear and vestibular neurons. Anat Embryol 189: 157-167
30. Ylikoski J, Pirvola U, Moshnyakov M, Palgi J, Arumae U, Saarma M 1993 Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear. Hear Res 56:69-78
31. Zhou X, Van De Water TR 1987 The effect of target tissues on survival and differentiation of mammalian statoacoustic ganglion neurons in organ culture. Acta Otolaryngol 104:90-98