Nocturnal melatonin levels in human volunteers exposed to intermittent 60 Hz magnetic fields

Bioelectromagnetics

Volumn 17, Issue 4, 1996, Pages 263-273

  Graham, Charles ^a   Cook, Mary R ^a   Riffle, Donald W ^a   Gerkovich, Mary M ^a   Cohen, Harvey D ^a  

^a MIDWEST RESEARCH INSTITUTE   (United States)

Author keywords

Cancer; ELF; EMF; Human; Neuroendocrine

Indexed keywords

HORMONES; MAGNETIC FIELDS;

CANCER; CIRCULARLY-POLARIZED; ELF; ENHANCED SENSITIVITY; EXPOSED TO; FIELD CONDITIONS; HUMAN; HUMAN VOLUNTEERS; MAGNETIC-FIELD; NEUROENDOCRINE;

MAMMALS;

RODENTIA;

MELATONIN;

ADOLESCENT; ADULT; ANIMAL; ARTICLE; BLOOD; CIRCADIAN RHYTHM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HUMAN; LIGHT; MAGNETISM; MALE; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SECRETION;

ADOLESCENT; ADULT; ANIMALS; CIRCADIAN RHYTHM; DOUBLE-BLIND METHOD; HUMANS; LIGHT; MAGNETICS; MALE; MELATONIN;

EID: 0030339257     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-186X(1996)17:4<263::AID-BEM2>3.0.CO;2-1     Document Type: Article

References (34)

1. Cohen HD, Graham C, Cook MR, Phelps JP (1992): ELF exposure facility for human testing. Bioelectromagnetics 13:169-182.
2. Coleman M, Beral V (1988): A review of epidemiological studies of the health effects of living near or working with electricity generation and transmission equipment. Int. J. Epidemiology 17.1-13.
3. Cook MR, Graham C, Cohen HD, Gerkovich MM (1992): A replication study of human exposure to 60-Hz fields: Effects on neurobehavioral measures. Bioelectromagnetics 13:261-285.
4. Federal Register (1991): Federal policy for the protection of human subjects: Notices and rules. Vol 56, No 117. June 18, 1991.
5. Graham C, Cook MR, Cohen HD (1990): Final Report: Immunological and Biochemical Effects of 60-Hz Electric and Magnetic Fields in Humans, Report DE90006671. Springfield, VA: National Technical Information Center.
6. Graham C, Cohen HD, Cook MR, Riffle DW, Huffman SJ, Gerkovich MM (1993a): Melatonin suppression and nocturnal exposure to 60-Hz magnetic fields in human volunteers. Abstracts, 13th Annual Meeting, Bioelectromagnetics Society, Los Angeles, p 67.
7. Graham C, Cook MR, Cohen HD, Riffle DW, Hoffman SJ, McClernon FJ, Smith D, Gerkovich MM (1993b): EMF suppression of nocturnal melatonin in human volunteers. Abstracts, DOE Annual Review of EMF Research, Savannah, GA, pp 98-99.
8. Graham C, Cook MR, Cohen HD, Gerkovich MM (1994a): A dose response study of human exposure to 60-Hz electric and magnetic fields. Bioelectromagnetics 15:447-463.
9. Graham C, Cook MR, and Cohen HD (1994b): Investigation of the effects of magnetic field exposure on human melatonin. Electric Power Research Institute, Report TR-104278.
10. Graham C, Cook MR, Cohen HD, Riffle DW (1994c): Nocturnal melatonin levels in men exposed to magnetic fields: A replication study. Abstracts, DOE Annual Review of EMF Research, Albuquerque, NM, pp 51-52.
11. Guttman JL, Zaffanella LE, Johnson GB (1994): Survey measurements and experimental studies of residential transient magnetic fields. EPRT TR-104532, Dec, 1994.
12. Hardeland R, Reiter RJ, Poeggeler B, Tan D-X (1993): The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances. Neurosci Biobehav Rev 17.347.
13. Hill SM, Blask DE (1988): Effects of the pineal hormone melatonin on proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture. Cancer Res 48:6121-6126.
14. Kato M, Honma K, Shigemitsu T, Shiga Y (1993): Effects of exposure to a circularly polarized 50-Hz magnetic field on plasma and pineal melatonin levels in rats. Bioelectromagnetics 14:97-106.
15. Lerchl A, Nonaka KO, Stokkan KA, Reiter RJ (1990): Marked rapid alterations in nocturnal pineal serotonin metabolism in mice and rats exposed to weak intermittent magnetic fields. Biochem Biophys Res Commun 169:102-108.
16. Lerchl A, Nonaka KO, Reiter RJ (1991): Pineal gland: Its apparent magnctosensitivity is a consequence of eddy currents. J Pineal Res 10:109-116.
17. Lewy AJ, Wehr TA, Goodwin FK, Newsome DA, Markey SP (1980): Light suppresses melatonin secretion in humans. Science 210:1267-1269.
18. Maestroni GJM (1993): The immunoneuroendocrine role of melatonin. J Pineal Res 14:1-10
19. Pieri C, Marra M, Moroni F, Recchioni R, Marcheselli F (1994): Melatonin: A peroxyl radical scavenger more effective than vitamin E. Life Sci 55:271.
20. Reiter RJ (1988): Pineal gland, cellular proliferation and neoplastic growth: An historical account. In Gupta D (ed): "The Pineal Gland and Cancer." Tubingen, Federal Republic of Germany: Brain Research Promotion, pp 41-64.
21. Reiter RJ (1989): The pineal and its indole products: Basic aspects and clinical applications. In Cohen MP, Foley PP (eds): "The Brain as an Endocrine Organ." Vienna: Springer, pp 96-149.
22. Reiter RJ (1993 ): A review of neuroendocrine and neurochemical changes associated with static and extremely low frequency electromagnetic field exposure. Integ Physiol Behav Sci 28:57-75.
23. Reiter RJ, Melchiorri D, Sewerynek E, Poeggler B, Barlow-Walden L, Chuang J-I, Ortiz GG, Acuna-Castroviejo D (1995): A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 18:1-11.
24. Rollag MD, Niswender GD (1976): Radioimmunoassay of serum concentrations of melatonin in sheep exposed to different lighting regimens. Endocrinology 98:482-489.
25. Sastre A, Kavet R, Guttman JL, Weaver JC (1994): Residential magnetic field transients: How do their induced transmembrane voltages compare to thermal noise? Abstracts, DOE Annual Review of EMF Research, Albuquerque, NM, pp 33-34.
26. Savitz DA, John EM, Kleckner RC (1989): Magnetic field exposure from electric appliances and childhood cancer. Am J Epidemiol 131:763-773
27. Stevens RG (1987): Electric power use and breast cancer. A hypothesis. Am J Epidemiol 125:556-561.
28. Tan D, Poeggeler B, Reiter RJ, Chen L, Chen S, Manchester LC, Barlow-Walden LR (1993): The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. Cancer Lett 70:65-71.
29. Theriault G (1991): Health effects of electromagnetic radiation on workers epidemiologic studies. "Scientific Workshop on the Health Effects of Electromagnetic Radiation on Workers", Report No. 91-37. Cincinnati, OH,: NIOSH.
30. Waldhauser F, Walentich W, Ehrhart B (1993): The physiological secretion pattern of melatonin in man. In Touitou Y, Arendt J, Pevet P (eds): "Melatonin and the Pineal Gland: From Basic Science to Clinical Application." New York: Elsevier Science Publishers, pp 331-338.
31. Wilson BW, Chess EK, Andersen LE (1986): 60-Hz electric-field effects on pineal melatonin rhythms: Time course for onset and recovery. Bioelectromagnetics 7:239-242.
32. Wilson BW, Stevens RG, Anderson LE (eds; 1990): "Extremely Low Frequency Electromagnetic Fields: The Question of Cancer." Columbus, OH: Battelle Press.
33. Yellon SM, Hilliker S (1994): The influence of acute melatonin treatment and light on the circadian melatonin rhythm in the Djungarian hamster. J Biol Rhythm 9:71-81.
34. Zimmermann RC, Schumacher M, Schroder S, Weise HC, Baars S (1990): Melatonin and the ovulatory luteinizing hormone surge. Fertil Steril 54:612-618.