Redesigning the substrate specificity of the hepatitis C virus NS3 protease

Folding and Design

Volumn 1, Issue 1, 1996, Pages 35-42

  Failla, Cristina Maria ^a   Pizzi, Elisabetta ^a   De Francesco, Raffaele ^a   Tramontano, Anna ^a  

^a IRBM   (Italy)

Author keywords

Hepatitis C virus; NS3 protease; Protease engineering; Structure prediction

Indexed keywords

NS3 PROTEIN, HEPATITIS C VIRUS; RECOMBINANT PROTEIN; SERINE PROTEINASE; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HELA CELL; HEPATITIS C VIRUS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STREPTOMYCES GRISEUS;

AMINO ACID SEQUENCE; BINDING SITES; DRUG DESIGN; HELA CELLS; HEPACIVIRUS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; STREPTOMYCES GRISEUS; SUBSTRATE SPECIFICITY; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0030334850     PISSN: 13590278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-0278(96)00010-7     Document Type: Article

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