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Volumn 398, Issue , 1996, Pages 493-497

Kynurenine-3-hydroxylase and Its Selective Inhibitors: Molecular Modeling Studies

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; ENZYME INHIBITOR; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; MIXED FUNCTION OXIDASE; NEUROPROTECTIVE AGENT;

EID: 0030332542     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4613-0381-7_76     Document Type: Article
Times cited : (2)

References (9)
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    • Entsch, B.; Ballou, D. P.; Massey, V., 1976, Flavin oxygen derivatives involved in hydroxylation by p-hydroxybenzoate hydroxylase. J. Biol. Chem. 251: 2550.
    • (1976) J. Biol. Chem. , vol.251 , pp. 2550
    • Entsch, B.1    Ballou, D.P.2    Massey, V.3
  • 2
    • 0021186590 scopus 로고
    • Kynurenic acid blocks neurotoxicity and seizures induced in rat by the related brain metabolite quinolinic acid
    • Foster, A. C.; Vezzani, A.; French, E. D.; Schwarcz, R., 1984, Kynurenic acid blocks neurotoxicity and seizures induced in rat by the related brain metabolite quinolinic acid. Neurosci. Lett. 48: 273
    • (1984) Neurosci. Lett. , vol.48 , pp. 273
    • Foster, A.C.1    Vezzani, A.2    French, E.D.3    Schwarcz, R.4
  • 3
    • 0026535226 scopus 로고
    • Neuroprotective effects of L-Kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats
    • Nozaki, K.; Beal, M., F., 1992, Neuroprotective effects of L-Kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J. Cerebr. Blood Flow Metab. 12: 400
    • (1992) J. Cerebr. Blood Flow Metab. , vol.12 , pp. 400
    • Nozaki, K.1    Beal, M.F.2
  • 4
    • 0026635842 scopus 로고
    • Stereospecific synthesis of the enantiomers of nicotinoylalanine, a neuroprotective agent
    • Pellicciari, R.; Gallo-Mezo, M. A.; Natalini, B.; Amer, A. M., 1992, Stereospecific synthesis of the enantiomers of nicotinoylalanine, a neuroprotective agent. Tetrahedron Lett. 33: 3003
    • (1992) Tetrahedron Lett. , vol.33 , pp. 3003
    • Pellicciari, R.1    Gallo-Mezo, M.A.2    Natalini, B.3    Amer, A.M.4
  • 5
    • 0028343956 scopus 로고
    • Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase
    • Pellicciari, R.; Natalini, B.; Costantino, G.; Mahmoud, R. M.; Mattoli, L.; Sadeghpour, B. M.; Moroni, F.; Chiarugi, A.; Carpenedo, R., 1994, Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase. J. Med. Chem. 37: 647
    • (1994) J. Med. Chem. , vol.37 , pp. 647
    • Pellicciari, R.1    Natalini, B.2    Costantino, G.3    Mahmoud, R.M.4    Mattoli, L.5    Sadeghpour, B.M.6    Moroni, F.7    Chiarugi, A.8    Carpenedo, R.9
  • 6
    • 0026499648 scopus 로고
    • Nicotinoylalanine increases the formation of the kynurenic acid in the brain and antagonizes convulsions
    • Russi, P.; Alesiani, M.; Lombardi G.; Davolio, P.; Pellicciari, R.; Moroni, F., 1992, Nicotinoylalanine increases the formation of the kynurenic acid in the brain and antagonizes convulsions. J. Neurochem. 59: 2076
    • (1992) J. Neurochem. , vol.59 , pp. 2076
    • Russi, P.1    Alesiani, M.2    Lombardi, G.3    Davolio, P.4    Pellicciari, R.5    Moroni, F.6
  • 7
    • 0024292226 scopus 로고
    • Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate
    • Schreuder, H. A.; van der Laan, J. M.; Hol, W. G. J.; Drenth, J., 1988, Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate. J. Mol. Biol. 199: 637
    • (1988) J. Mol. Biol. , vol.199 , pp. 637
    • Schreuder, H.A.1    Van Der Laan, J.M.2    Hol, W.G.J.3    Drenth, J.4
  • 8
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    • Metabolism and function of brain kynurenines
    • Schwarcz, R., 1993, Metabolism and function of brain kynurenines. Biochem. Soc. Trans. 21:77
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 77
    • Schwarcz, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.