Kynurenines and anxiety

Advances in Experimental Medicine and Biology

Volumn 398, Issue , 1996, Pages 191-194

  Lapin, I P ^a  

^a Bekhterev St Petersburg Psychoneurological Research Institute   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ANXIOLYTIC AGENT; DRUG DERIVATIVE; KYNURENINE;

ANIMAL; ANXIETY; BLOOD; CHEMISTRY; DRUG EFFECT; HUMAN; MAZE TEST; MOOD DISORDER; MOUSE; PHYSIOLOGY; RAT; REVIEW;

ANIMALS; ANTI-ANXIETY AGENTS; ANTICONVULSANTS; ANXIETY; HUMANS; KYNURENINE; MAZE LEARNING; MICE; MOOD DISORDERS; RATS;

EID: 0030332538     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4613-0381-7_31     Document Type: Article

References (18)

1. Lapin, I.P., 1972, Interaction of kynurenine and its metabolites with tryptamine, serotonin and its precursors and oxotremorine, Psychopharmacologia 26:237.
2. Lapin, I.P., 1973a, Neurotropic activities of kynurenine and its metabolites, in : "Symposium on Pharmacological Agents and Biogenic Amines in the Central Nervous System, J. Knoll and K. Magyar, ed., Akademiai Kiado, Budapest, 149-164.
3. Lapin, I.P., 1973b, Kynurenines as probable participants of depression, Pharmakopsychiatrie-Neuropsychopharmakologie 6: 273.
4. Lapin, I.P., 1974, Antagonism of nicotinic acid and other kynurenines to antidepressants: one of probable reasons of the therapy-resistance in depression? Activitas nerv. Super. (Prague) 16: 260.
5. Lapin, I.P., 1976, Depressor effect of kynurenine and its metabolites in rats, Life Sci. 19: 1479.
6. Lapin, I.P., 1978a, Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice, J.Neural Transm 42:37.
7. Lapin, I.P., 1978b, Convulsions and tremor in immature rats after intraperitoneal injection of kynurenine and its metabolites, Pharmacol.Res. Commun. 10:81.
8. Lapin, I.P., 1980, Experimental studies on kynurenines as neuroactive metabolites: past, present and future, Trends in Pharmacol Sci. 1: 410.
9. Lapin, I.P., 1981, Kynurenines and seizures, Epilepsia 22:257.
10. Lapin, I.P., 1985, Endogenous antagonists of quinolinic acid and kynurenine as links of the defensive mechanism in epilepsy, Acta Neurologica 40:203.
11. Lapin, I.P., Prakhie, I.V., and Kiseleva, I.P., 1986, Antagonism of seizures induced by the administration of the endogenous convulsant quinolinic acid into rat brain ventricles. J.Neural Transmis. 65:177.
12. Lapin, I.P., 1989, Behavioral and convulsant effects of kynurenines, in: "Quinolinic Acid and the Kynurenines," T.W. Stone, ed., CRC Press, Boca Raton, 193-211.
13. Lapin, I.P., 1990, Beta-phenylethylamine (PEA): an endogenous anxiogen? Three series of experimental data, Biol. Psychiatry 28:997.
14. Lapin, I.P., 1995, Anxiogenic activity of quinolinic acid and kynurenine in the social interaction test in mice, J. of Psychopharmacology (in press).
15. Lapin, I.P., and Politi, V., 1993, Anxiolytic effect of indole-3-pyruvic acid in mice, Pharmacol. Res. 28:129.
16. Orlikov, A.B., and Lapin, I.P., 1993, Examining the mechanisms of anxiety by anxiogens: clinical and expreimental evidence (Review, 86 ref.), Exper. and clinical Pharmacology (Moscow) 56:59.
17. Orlikov, A.B., Prakhie, I.B., and Ryzov, I.V., 1994, Kynurenine in blood plasma and DST in patients with endogenous anxiety and endoxenous depression, Biol. Psychiatry 36:97.
18. Orlikov, A.B., and Ryzov, I.V., 1991, Caffeine-induced anxiety and increase of kynurenine concentration in plasma of healthy subjects:a pilot study, Biol. Psychiatry 29:391.