A porcine model of peritonitis and bacteremia simulates human septic shock

Shock

Volumn 6, Issue 6, 1996, Pages 442-451

  Goldfarb, Roy D ^a   Glock, Dana ^a   Kumar, Anand ^a   McCarthy, Robert J ^a   Mei, J ^a   Guynn, Todd ^a   Matushek, Marian ^a   Trenholme, Gordon ^a   Parrillo, Joseph E ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; BACTEREMIA; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; CELL CULTURE; CORONARY ARTERY BLOOD FLOW; CYTOLOGY; DISEASE MODEL; ESCHERICHIA COLI; FEMALE; HEART MUSCLE; HEART OUTPUT; HEART RATE; METABOLISM; MICROBIOLOGY; MORTALITY; PATHOGENICITY; PATHOPHYSIOLOGY; PERITONITIS; RAT; SEPTIC SHOCK; SURVIVAL RATE; SWINE; TIME; TRANSPLANTATION; VASCULAR RESISTANCE;

ANIMALS; BACTEREMIA; BLOOD PRESSURE; CARDIAC OUTPUT; CARDIOVASCULAR SYSTEM; CELLS, CULTURED; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI; FEMALE; HEART RATE; MYOCARDIUM; PERITONITIS; RATS; SHOCK, SEPTIC; SURVIVAL RATE; SWINE; TIME FACTORS; TRANSPLANTATION; VASCULAR RESISTANCE;

EID: 0030331449     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199612000-00009     Document Type: Article

References (36)

1. Natanson C, Fink MP, Ballantyne HK, MacVinie TJ, Conklin JC, Parrillo JE: Gram-negative bacteremia produces both severe systolic and diastolic cardiac dysfunction in a canine model that simulates human septic shock. J Clin Invest 78:259-270, 1986.
2. Parker MM, Shelhammer JL, Green MV, et al: Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med 100:483, 1984.
3. Cunnion RE, Schaer GL, Parker MM, Natanson C, Parrillo JE: The coronary circulation in human septic shock. Circulation 73:637-644, 1986.
4. Astiz, M, Rackow EC, Weil MH, Schumer W: Early impairment of oxidative metabolism and energy production in severe sepsis. Circ Shock 26:311-320, 1988.
5. Rackow EC, Astiz ME, Weil MH: Cellular oxygen metabolism during sepsis and shock. JAMA 259:1989-1993, 1988.
6. Luce JM: Pathogenesis and management of septic shock. Chest 91:883-888, 1987.
7. Parker MM, Suffredini AF, Natanson C, Ognibene FP, Parrillo JE: Responses of left ventricular function in survivors and nonsurvivors of septic shock. J Crit Care Med 4:19-25, 1989.
8. Suffredini AF, Fromm RE, Parker MM, et al: The cardiovascular response of normal humans to the administration of endotoxin. N Engl J Med 321:280-287, 1989.
9. Goldfarb RD, Nightingale LM, Kish P, Weber PB, Loegering DJ: Left ventricular function during lethal and sublethal endotoxemia in swine. Am J Physiol 251:H364-H373, 1986.
10. Breslow MJ, Miller CF, Parker S, Walman AT, Traystman RJ: Effect of catecholamines on organ blood flow during endotoxin shock in the pig. Crit Care Med 12:246, 1984.
11. Walvatne CS, Johnson AS, Wojcik LJ, Cerra FB: Cardiovascular response to acute and chronic endotoxemia in an awake, volume-resuscitated, canine model. Shock 3:299-307, 1995.
12. Fish RE, Burns AH, Lang CH, Spitzer JA: Myocardial dysfunction in a non-lethal, non-shock model of chronic endotoxemia. Circ Shock 16:241-252, 1985.
13. Lee KJ, Dziuban SW Jr, van der Zee H, Goldfarb RD: Cardiac function and coronary flow in chronic endotoxemia pigs. Proc Soc Exp Biol Med 189:245-252, 1988.
14. Lee KJ, van der Zee H, Dziuban SW Jr, Goldfarb RD: Left ventricular function during chronic endotoxemia in swine. Amer J Physiol 254:H324-H330, 1988.
15. Fish RE, Spitzer JA: Continuous infusion of endotoxin from an osmotic pump in the conscious, unrestrained rat: A unique model of chronic endotoxemia. Circ Shock 12:135-149, 1984.
16. Dodds WJ: The pig as a model for cardiovascular research. Fed Proc 41:247-256, 1982.
17. Sagawa K: The ventricular pressure-volume diagram revisited. Circ Res 43:677-687, 1978.
18. Schuette WH, Burch C, Roach PO, Parrillo JE: Closed loop television tracking of beating heart cells in vitro. Cytometry 8:101-103, 1987.
19. Kumar A, Thota V, Dee L, Olsen J, Uretz E, Parrillo JE: Tumor necrosis factor-α and interleukin-1 are responsible for m vitro myocardial cell depression induced by human septic shock. J Exp Med 183:949-958, 1996.
20. Parrillo JE, Parker MM, Natanson C, et al: Septic shock in humans. Ann Intern Med 113:227-242, 1990.
21. Parrillo JE: Pathogenic mechanisms of septic shock. N Engl J Med 328:1471-1477, 1993.
22. Nishijima H, Weil MH, Shubin H, Cavanilles J: Hemodynamic and metabolic studies on shock associated with Gram-negative bacteremia. Medicine 52:287-294, 1973.
23. Udhoji VN, Weil MH: Hemodynamic and metabolic studies on shock associated with bacteremia. Ann Intern Med 62:966-978, 1965.
24. Weil MH, Shubin H, Biddle M: Shock caused by Gram-negative microorganisms. Ann Intern Med 60:384-400, 1964.
25. Clowes GHA, Famngton GH, Zuschneid W, Cossette, GR, Saravis C: Circulating factors in the etiology of pulmonary insufficiency and right heart failure accompanying severe sepsis. Ann Surg 171:663-678, 1970.
26. Kwaan HM, Weil MH: Differences in the mechanism of shock caused by bacterial infections. Surg Gynecol Obstet 128:37-45, 1969.
27. Shoemaker WC: Cardiorespiratory patterns in complicated, uncomplicated septic shock. Ann Surg 174:119-125, 1971.
28. Packman MI, Rackow EC: Optimum left heart filling pressure during fluid resuscitation of patients with hypovolemic and septic shock. Crit Care Med 11:165-169, 1983.
29. Weisel RD, Vito L, Dennis RC, Valeri CR, Hechtman HB: Myocardial depression during sepsis. Am J Surg 133:512-521, 1977.
30. Parrillo JE, Burch C, Shelhammer JH, Parker MM, Natanson C, Schuette W: A circulating myocardial depressant substance in human septic shock. J Clin Invest 76:1539-1553, 1985.
31. Reilly JM, Cunnion RE, Burch-Whitman C, Parker MM, Natanson C, Parrillo JE: A circulating myocardial depressant substance is associated with cardiac dysfunction and peripheral hypoperfusion (lactic acidemia) in patients with septic shock. Chest 95:1072-1090, 1989.
32. Kararian KK, Perdue PW, Lynch W, et al: Porcine peritoneal sepsis: Modeling for clinical relevance. Shock 1:201-212, 1994.
33. Solomon MA, Correa R, Natanson C, et al: Ultrastructural and histological changes associated with myocardial depression in a canine model of septic shock. Clin Res 39:321A, 1991.
34. Abel FL: Myocardial function in sepsis and endotoxin shock. Am J Physiol 257:R1265-R1281, 1989.
35. Suga H: Ventricular energetics. Physiol Rev 70:247-277, 1990.
36. Kumar A, Kosuri R, Kandula P, Olsen J, Uretz G, Parrillo JE: Cardiomyocyte depression induced by human septic serum is mediated by nitric oxide and cyclic GMP generation. Crit Care Med 22:A119, 1994.