Prospects for gene therapy in sports medicine

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 4, Issue 3, 1996, Pages 180-187

  Gerich, T G ^a   Fu, F H ^b   Robbins, P D ^b   Evans, C H ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Articular; Cartilage; Gene transfer; Growth factors; Ligaments; Menisci

Indexed keywords

CYTOKINE; GROWTH PROMOTOR;

FORECASTING; GENE THERAPY; GENE TRANSFER; HUMAN; METHODOLOGY; REVIEW; SPORT INJURY; SPORTS MEDICINE; WOUND HEALING;

ATHLETIC INJURIES; CYTOKINES; FORECASTING; GENE THERAPY; GENE TRANSFER TECHNIQUES; GROWTH SUBSTANCES; HUMANS; SPORTS MEDICINE; WOUND HEALING;

EID: 0030331441     PISSN: 09422056     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01577414     Document Type: Article

References (10)

1. Amoczky SP, Warren RF (1983) The microvasculature of the meniscus and its response to injury. Am J Sports Med 11:131-141
2. Arnoczky SP, Warren R, Spivak J (1988) Meniscal repair using an exogenous fibrin clot: an experimental study in dogs. J Bone Joint Surg [Am] 70:1209-1217
3. Axelrod JH, Read MS, Brinkhous KM, Verma IM (1990) Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilie dogs. Proc Natl Acad Sci USA 87:5173-5177
4. Bandara G, Robbins RD, Georgescu HI, Mueller GM, Glorioso JC, Evans CH (1992) Gene transfer to synoviocytes: prospects for gene treatment for arthritis. DMA Cell Biol 11:227-231
5. Bandara G, Mueller GM, Galea-Lauri J, Tindal MH, Georgescu HI, Suchanek MK, Hung GL, Glorioso JC, Robbins RD, Evans CH (1993) Intraarticular expression of biologically active interleukin-1 receptor antagonist protein by ex vivo gene transfer. Proc Natl Acad Sci USA 90:10764-10768
6. Varmus HE (1982) Form and function of retroviral proviruses. Science 216: 812-820
7. Walsh CE, Liu JM, Xiao X, Young NS, Nienhuis AW, Samulski RJ (1992) Regulated high level expression of a human γ-globulin gene introduced into erythroid cells by an adeno-associated virus vector. Proc Natl Acad Sci 89:7257-7261
8. Williams RS, Rossi AM, Chegini N, Schultz G (1992) Effect of transforming growth factor β on postoperative adhesion formation and intact peritoneum. J Surg Res 52:65-70
9. Yang Y, Nunes FA, Berensci K, Furth EE, Gonzcol E, Wilson JM (1994) Cellular immunity to viral antigens limits E1-detected adenovirus for gene therapy. Proc Natl Acad Sci USA 91:4407-4411
10. Zionchek TE, Chen SA, Richardson L, Mora-Worms M, Lucas C, Lewis D, Green JD, Mordenti J (1994) Pharmacokinetics and tissue distribution of recombinant human transforming growth factor beta 1 after topical and intravenous administration in male rats. Pharm Res 11:213-220