Isolation and partial characterization of a high molecular weight anionic glycoconjugate from transforming growth factor-β treated bovine articular chondrocyte cultures

Biochemistry and Cell Biology

Volumn 74, Issue 2, 1996, Pages 233-240

  Anastassiades, Tassos P ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Anionic glycoconjugate synthesis; Chondrocytes; Transforming growth factor

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; CARBOHYDRATE; GLYCOPROTEIN; N ACETYLNEURAMINIC ACID; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; ARTICULAR CARTILAGE; CATTLE; CELL CULTURE; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECT; GEL CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS;

AMINO ACIDS; ANIMALS; BIOLOGICAL MARKERS; CARBOHYDRATES; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHROMATOGRAPHY, GEL; CULTURE MEDIA, CONDITIONED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOPROTEINS; MOLECULAR WEIGHT; N-ACETYLNEURAMINIC ACID; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030331221     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o96-024     Document Type: Article

References (4)

1. Cheifez, S., Weatherbee, J., Tsang, M., Anderson, J., Mole, J., Lucas, R., and Massagué, J. 1987. The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors. Cell, 48: 409-415.
2. Fava, R., Olsen, N., Keski-Oja, J., Moses, H., and Pincus, T. 1989. Active and latent forms of transforming growth factor β activity in synovial effusions. J. Exp. Med. 169: 291-296.
3. Fife, R. 1985. Identification of link proteins and a 116,000-dalton matrix protein in canine meniscus. Arch. Biochem. Biophys. 240: 682-688.
4. Fife, R. 1986. Alterations in a cartilage matrix glycoprotein in canine osteoarthritis. Arthritis Rheum. 29: 1493-1500.