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Volumn 74, Issue 3, 1996, Pages 403-410

KATP channel-dependent and -independent pathways of insulin secretion in isolated islets from fa/fa Zucker rats

Author keywords

ATP dependent K channels; Insulin secretion; Obesity; Pancreatic islet; Zucker rat

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIAZOXIDE; GLUCOSE; INSULIN; MANNOHEPTULOSE; POTASSIUM CHANNEL; RUBIDIUM;

EID: 0030330587     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o96-043     Document Type: Article
Times cited : (19)

References (22)
  • 2
    • 0025300438 scopus 로고
    • Properties and functions of ATP-sensitive K-channels
    • Ashcroft, S.J.H., and Ashcroft, F.M. 1990. Properties and functions of ATP-sensitive K-channels. Cell. Signalling, 2: 197-214.
    • (1990) Cell. Signalling , vol.2 , pp. 197-214
    • Ashcroft, S.J.H.1    Ashcroft, F.M.2
  • 3
    • 0023951059 scopus 로고
    • Properties of single potassium channels modulated by glucose in rat pancreatic β-cells
    • Ashcroft, F.M., Ashcroft, S.J.H., and Harrison, D.E. 1988. Properties of single potassium channels modulated by glucose in rat pancreatic β-cells. J. Physiol. (Camb.), 400: 501-527.
    • (1988) J. Physiol. (Camb.) , vol.400 , pp. 501-527
    • Ashcroft, F.M.1    Ashcroft, S.J.H.2    Harrison, D.E.3
  • 5
    • 0026020138 scopus 로고
    • Effect of pertussis toxin on islet insulin secretion in obese (fa/fa) Zucker rats
    • Cawthorn, E.G., and Chan, C.B. 1991. Effect of pertussis toxin on islet insulin secretion in obese (fa/fa) Zucker rats. Mol. Cell. Endocrinol. 75: 197-204.
    • (1991) Mol. Cell. Endocrinol. , vol.75 , pp. 197-204
    • Cawthorn, E.G.1    Chan, C.B.2
  • 6
    • 0027482029 scopus 로고
    • Glucokinase activity in isolated islets from obese fa/fa Zucker rats
    • Chan, C.B. 1993. Glucokinase activity in isolated islets from obese fa/fa Zucker rats. Biochem. J. 295: 673-677.
    • (1993) Biochem. J. , vol.295 , pp. 673-677
    • Chan, C.B.1
  • 7
    • 0027057022 scopus 로고
    • Reduced sensitivity to dexamethasone of pancreatic islets from obese (fa/fa) rats
    • Chan, C.B., and Lejeune, J. 1992. Reduced sensitivity to dexamethasone of pancreatic islets from obese (fa/fa) rats. Can. J. Physiol. Pharmacol. 70: 1518-1522.
    • (1992) Can. J. Physiol. Pharmacol. , vol.70 , pp. 1518-1522
    • Chan, C.B.1    Lejeune, J.2
  • 9
    • 0027300883 scopus 로고
    • Evidence for defective glucose sensing by islets of fa/fa obese Zucker rats
    • Chan, C.B., MacPhail, R.M., and Mitton, K. 1993. Evidence for defective glucose sensing by islets of fa/fa obese Zucker rats. Can. J. Physiol. Pharmacol. 71: 34-39.
    • (1993) Can. J. Physiol. Pharmacol. , vol.71 , pp. 34-39
    • Chan, C.B.1    MacPhail, R.M.2    Mitton, K.3
  • 10
    • 0030045958 scopus 로고    scopus 로고
    • Modulation by glucose of insulin secretion and glucose phosphorylating activity in cultured pancreatic islets from obese (fa/fa) Zucker rats
    • Chan, C.B., Lowe, J.M., and Debertin, W.J. 1996. Modulation by glucose of insulin secretion and glucose phosphorylating activity in cultured pancreatic islets from obese (fa/fa) Zucker rats. Int. J. Obes. 20: 175-184.
    • (1996) Int. J. Obes. , vol.20 , pp. 175-184
    • Chan, C.B.1    Lowe, J.M.2    Debertin, W.J.3
  • 11
    • 0028140161 scopus 로고
    • Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells
    • Detimary, P., Gilon, P., Nenquin, M., and Henquin, J.-C. 1994. Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells. Biochem. J. 297: 455-461.
    • (1994) Biochem. J. , vol.297 , pp. 455-461
    • Detimary, P.1    Gilon, P.2    Nenquin, M.3    Henquin, J.-C.4
  • 13
    • 0028261893 scopus 로고
    • Mechanisms of pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes
    • Flatt, P.R., Barnett, C.R., and Swanston-Flatt, S.K. 1994. Mechanisms of pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes. Biochem. Soc. Trans. 22: 87-92.
    • (1994) Biochem. Soc. Trans. , vol.22 , pp. 87-92
    • Flatt, P.R.1    Barnett, C.R.2    Swanston-Flatt, S.K.3
  • 14
    • 0025126496 scopus 로고
    • +-induced membrane depolarization on insulin secretion in islets of lean and obese (ob/ob) mice
    • +-induced membrane depolarization on insulin secretion in islets of lean and obese (ob/ob) mice. Biochem. Cell. Biol. 68: 243-248.
    • (1990) Biochem. Cell. Biol. , vol.68 , pp. 243-248
    • Fournier, L.1    Heick, H.M.C.2    Bégin-Heick, N.3
  • 18
    • 0026333684 scopus 로고
    • The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet β-cells in the isolated perfused rat pancreas
    • Ghosh, A., Ronner, P., Cheong, E., Khalid, P., and Matschinsky, F.M. 1991. The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet β-cells in the isolated perfused rat pancreas. J. Biol. Chem. 266: 22 887-22 892.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22887-22892
    • Ghosh, A.1    Ronner, P.2    Cheong, E.3    Khalid, P.4    Matschinsky, F.M.5
  • 19
    • 0026635879 scopus 로고
    • + channels may not be the sole regulators of glucose-induced electrical activity in pancreatic B-cells
    • + channels may not be the sole regulators of glucose-induced electrical activity in pancreatic B-cells. Endocrinology, 131: 127-131.
    • (1992) Endocrinology , vol.131 , pp. 127-131
    • Henquin, J.-C.1
  • 20
    • 0028641418 scopus 로고
    • Multisite control of insulin release by glucose
    • Henquin, J.-C. 1994. Multisite control of insulin release by glucose. Diabete Metab. (Paris), 20: 132-137.
    • (1994) Diabete Metab. (Paris) , vol.20 , pp. 132-137
    • Henquin, J.-C.1
  • 21
    • 0029266490 scopus 로고
    • Identification of biochemical defects in pancreatic islets of fa/fa rats: A developmental study
    • Kibenge, M.T., and Chan, C.B. 1995. Identification of biochemical defects in pancreatic islets of fa/fa rats: a developmental study. Obes. Res. 3: 171-178.
    • (1995) Obes. Res. , vol.3 , pp. 171-178
    • Kibenge, M.T.1    Chan, C.B.2
  • 22
    • 0030061740 scopus 로고    scopus 로고
    • The effect of adrenalectomy on the development of a pancreatic islet lesion in fa/fa rats
    • Kibenge, M.T., and Chan, C.B. 1996. The effect of adrenalectomy on the development of a pancreatic islet lesion in fa/fa rats. Diabetologia, 39: 190-198.
    • (1996) Diabetologia , vol.39 , pp. 190-198
    • Kibenge, M.T.1    Chan, C.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.