Increase of gentamicin uptake in cultured mouse peritoneal macrophage and rat hepatocytes when used in the form of nanoparticles

Yaoxue Xuebao

Volumn 31, Issue 5, 1996, Pages 375-380

  Zhang, Q ^a,b   Liao, G T ^a   Wei, D P ^a   Zhang, C J ^a  

^a SICHUAN UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Gentamicin; Mouse peritoneal macrophage; Nanopaticles; Rat hepatocytes; Uptake in vitro

Indexed keywords

GENTAMICIN; MICROSPHERE;

ANIMAL; ARTICLE; CYTOLOGY; DRUG DELIVERY SYSTEM; IN VITRO STUDY; LIVER; METABOLISM; MOUSE; PERITONEUM MACROPHAGE; RAT; WISTAR RAT;

ANIMALS; DRUG DELIVERY SYSTEMS; GENTAMICINS; LIVER; MACROPHAGES, PERITONEAL; MICE; MICROSPHERES; RATS; RATS, WISTAR;

EID: 0030325623     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Michelland SH, Alonso MJ, Andremont A et al. Attachment of antibiotics to nanoparticles: preparation, drug-release and antimicrobial activity in vitro. Int J Pharm, 1987, 35 : 121
2. Youssef M, Fattal E, Alonso MJ et al. Effectiveness of nanoparticle bound ampicillin in athymic nude mice. Antimicrob Agents Chemother, 1988, 32: 1204
3. Fattal E, Youssef M, Couvreur P et al. Treatment of experimental Salmonellosis in mice with ampicillin-bound nanoparticles. Antimicrob Agents Chemother, 1989, 33 : 1540
4. Guise V, Jaffray P, Delattre J et al. Comparative cell uptake of propidium iodide associated with liposomes or nanoparticles. Cell Mol Biol, 1987, 33 : 397
5. Rolland A, Begue JM, Verge RL et al. Increase of doxorubicin penetration in cultured rat hepatocytes by its binding to polymethacrylic nanoparticles. Int J Pharm, 1989, 53 : 67