Method for assessing the duration of therapeutic action and milligram equivalence of anxiolytics

Anxiety

Volumn 2, Issue 1, 1996, Pages 40-46

  Sheehan, David V ^a,c   Raj, Ashok B ^a   Harnett Sheehan, K ^a   Dorotheo, Jocelyn ^a   Sheehan, Michael F ^a   Trehan, Rajeev ^a   Knapp, Edson ^a   Swiontek, Ann ^b   Coleman, Bernard ^b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Agoraphobia; Alprazolam CT; Alprazolam XR; Anxiety; Duration of therapeutic action; Extended release benzodiazepines; Panic attacks; Panic disorder

Indexed keywords

ALPRAZOLAM; ANXIOLYTIC AGENT;

ADOLESCENT; ADULT; AGED; AGORAPHOBIA; ANXIETY DISORDER; ARTICLE; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DOSE RESPONSE; DRUG ADMINISTRATION; FEMALE; HUMAN; MALE; MIDDLE AGED; PANIC; PHARMACOKINETICS; PSYCHOLOGICAL ASPECT; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGORAPHOBIA; ALPRAZOLAM; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; PANIC DISORDER; THERAPEUTIC EQUIVALENCY; TREATMENT OUTCOME;

EID: 0030325233     PISSN: 10709797     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-7154(1996)2:1<40::AID-ANXI6>3.0.CO;2-H     Document Type: Article

References (21)

1. Alexander PE (1993) Alprazolam-XR in the treatment of panic disorder: Results of a randomized, double-blind, fixed-dose, placebo-controlled, multi-center study. Psychiatr Annals 23(10 suppl):14-19.
2. Ballenger JC, Burrows GD, DuPont RL, Lesser IM, Noyes R Jr, Pecknold JC, Rifkin A, Swinson RP (1988) Alprazolam in panic disorder and agoraphobia: Results from a multi-center trial, I. Efficacy in short-term treatment. Arch Gen Psychiatry 45:413-422.
3. Charney DS, Woods SW, Goodman WK, Rykin B, Kinch M, Aiken B, Quadrino LM, Heninger GR (1986) Drug treatment of panic disorder. J Clin Psychiatry 47:580-586.
4. Chouinard G, Annable L, Fontaine R, Solyom L (1982) Alprazolam in the treatment of generalized anxiety and panic disorders: A double-blind, placebo-controlled study. Psychopharmacology 77:229-233.
5. Ciraulo DA, Barnhill JG, Boxenbaum HG, Greenblatt DJ, Smith RB (1986) Pharmacokinetics and clinical effects of alprazolam following single and multiple oral doses in patients with panic disorder. J Clin Pharmacol 26:292-298.
6. Dunner DL, Ishiki D, Avery DH, Wilson LG, Hyde TS (1986) Effect of alprazolam and diazepam on anxiety and panic attacks in panic disorder: A controlled study. J Clin Psychiatry 47:458-460.
7. Greenblatt DJ, Shader RI, Abernathy DR (1983) Current status of benzodiazepines (first of two parts). N Engl J Med 309:354-358.
8. Herman J (1988) "Interview." Currents in Affective Illness 7:5-10.
9. Howell EF, Larsis M, Ballenger JC, Lydiard RB (1987) Lorazepam treatment of panic disorder. Presented at the 140th Annual Meeting of the American Psychiatric Association, Chicago, May 11, 1987.
10. Noyes R, Anderson DJ, Clancy J, Crowe RR, Symen DJ, Ghoneim MM, Hindrichs JV (1984) Diazepam and propranolol in panic disorder and agoraphobia. Arch Gen Psychiatry 41:287-292.
11. Pecknold J, Alexander PE, Munjack D (1993) Alprazolam-XR in the management of anxiety: Discontinuation. Psychiatr Ann 23(10 suppl):38-44.
12. Pecknold J, Lorenz L, Munjack D, Alexander P (1994) A double-blind, placebo-controlled, multicenter study with alprazolam and extended-release alprazolam in the treatment of panic disorder. J Clin Psychopharm 14:314-321.
13. Schweizer E (1993) Once daily control of panic disorder: Evidence from a placebo-controlled study of alprazolam-XR. Psychiatr Ann 23(10 suppl):32-37.
14. Sheehan DV (1982) Current perspectives on the treatment of panic and phobic disorders. Drug Therapy 12:49-63.
15. Sheehan DV, Coleman JH, Greenblatt DJ, Jones KJ, Levine PH, Orsulak PJ, Peterson M, Schildkraut JJ, Uzogara E, Watkins D (1984) Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. J Clin Psychopharm 4:66-75.
16. Sheehan DV (1986) The Anxiety Disease. New York: Bantam Books (revised paperback edition).
17. Sheehan DV, Raj AB, Soto S (1986) Panic Attack Diary. Tampa, Florida: University of South Florida Department of Psychiatry.
18. Sheehan DV, Raj AB, Harnett-Sheehan K, Soto S, Lewis CP (1990a) Adinazolam sustained release formulation in the treatment of generalized anxiety disorder. J Anx Dis 4:239-246.
19. Sheehan DV, Raj AB, Harnett-Sheehan K, Soto S, Lewis CP (1990b) Adinazolam sustained release formulation in the treatment of panic disorder: A pilot study. Ir J Psychol Med 7:124-128.
20. Spier SA, Tesar GE, Rosenbaum I, Woods SW (1986) Treatment of panic disorder and agoraphobia with clonazepam. J Clin Psychiatry 47:238-242.
21. Stahl S (1993) Alprazolam-XR: Dosage considerations. Psychiatric Annals 23(10 suppl):27-31.