Molecular regulation of cellular invasion-role off gelatinase A and TIMP-2

Biochemistry and Cell Biology

Volumn 74, Issue 6, 1996, Pages 823-831

  Yu, Anita E ^a   Hewitt, Robert E ^a   Kleiner, David E ^a   Stetler Stevenson, William G ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Activation; Extracellular matrix; Gelatinases; Metalloproteinase; Tissue inhibitors of metalloproteinases

Indexed keywords

GELATINASE; GELATINASE A; METALLOPROTEINASE; PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

AMINO ACID SEQUENCE; ANIMAL; CANCER INVASION; ENZYMOLOGY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENETICS; HUMAN; NEOPLASM; PATHOLOGY; PHYSIOLOGY; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; EXTRACELLULAR MATRIX; GELATINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 2; METALLOENDOPEPTIDASES; NEOPLASM INVASIVENESS; NEOPLASMS; PROTEINS; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 0030325052     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o96-088     Document Type: Article

References (3)

1. Autio-Harmainen, H., Karttunen, T., Hurskainen, T., Hoyhtya, M., Kauppila, A., and Tryggvason, K. 1993. Expression of 72 kilo dalton type IV collagenase (gelatinase A) in benign arid malignant ovarian tumors. Lab. Invest. 69: 312-321.
2. Banyai, L., Tordai, H., and Patthy, L. 1994. The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A). Biochem. J. 298: 403-407.
3. Barsky, S.H., Siegal, O.P., Jannotta, F., and Liotta, L.A. 1983. Loss of basement membrane components by invasive tumors but not by their benign counterparts. Lab. Invest. 49: 140-147.