메뉴 건너뛰기




Volumn 1, Issue 3, 1996, Pages 231-238

Solubility enhancement of a bisnaphthalimide tumoricidal agent, DMP 840, through complexation

Author keywords

1H NMR; Complexation; Nicotinamide; Solubility; Tumoricidal

Indexed keywords

ACETIC ACID; ANTINEOPLASTIC AGENT; BISNAFIDE MESYLATE; CHLORIDE ION; NICOTINAMIDE; PYRIDOXINE;

EID: 0030317020     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.3109/10837459609022591     Document Type: Article
Times cited : (10)

References (19)
  • 2
    • 0028348380 scopus 로고
    • (R,R)-2,2′-[1,2-Ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethane-sulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro
    • M. R. Kirschenbaum, S-F. Chen, C. H. Behrens, L. M. Papp, M. M. Stafford, J-H. Sun, D. L. Behrens, J. R. Fredericks, S. T. Polkus, P. Sipple, A. D. Patten, D. Dexter, S. P. Seitz, and J. L. Gross, (R,R)-2,2′-[1,2-Ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]-bis[5- nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethane-sulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro, Cancer Res., 54, 2199-2206 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 2199-2206
    • Kirschenbaum, M.R.1    Chen, S.-F.2    Behrens, C.H.3    Papp, L.M.4    Stafford, M.M.5    Sun, J.-H.6    Behrens, D.L.7    Fredericks, J.R.8    Polkus, S.T.9    Sipple, P.10    Patten, A.D.11    Dexter, D.12    Seitz, S.P.13    Gross, J.L.14
  • 3
    • 0026333702 scopus 로고
    • Nuclear magnetic resonance investigation of the stoichiometries in β-cyclodextrin:steroid inclusion complexes
    • F. Djedaini and B. Perly, Nuclear magnetic resonance investigation of the stoichiometries in β-cyclodextrin:steroid inclusion complexes, J. Pharm. Sci., 80, 1157-1161 (1991).
    • (1991) J. Pharm. Sci. , vol.80 , pp. 1157-1161
    • Djedaini, F.1    Perly, B.2
  • 4
    • 0002000565 scopus 로고
    • Inclusion properties of hydrophobic derivatives of cyclodextrins (CDs)
    • O. Huber and J. Szejtli, eds., Kluwer Academic Publishers, Dordrecht
    • G. Wenz and E. von der Bey, Inclusion properties of hydrophobic derivatives of cyclodextrins (CDs), in Proceedings of the Fourth International Symposium on Cyclodextrins (O. Huber and J. Szejtli, eds.), Kluwer Academic Publishers, Dordrecht, 1988, pp. 133-138.
    • (1988) Proceedings of the Fourth International Symposium on Cyclodextrins , pp. 133-138
    • Wenz, G.1    Von Der Bey, E.2
  • 5
    • 0001511660 scopus 로고
    • Recherches sur la formation de complexes mineraux en solution et sur leur stabilite
    • P. Job, Recherches sur la formation de complexes mineraux en solution et sur leur stabilite, Ann. Chem., 9, 113-134 (1928).
    • (1928) Ann. Chem. , vol.9 , pp. 113-134
    • Job, P.1
  • 7
    • 0002911353 scopus 로고
    • Solubilization of drugs by cosolvents
    • S. H. Yalkowsky, ed., Marcel Dekker, New York
    • S. H. Yalkowsky and T. J. Roseman, Solubilization of drugs by cosolvents, in Techniques of Solubilization of Drugs (S. H. Yalkowsky, ed.), Marcel Dekker, New York, 1981, pp. 91-134.
    • (1981) Techniques of Solubilization of Drugs , pp. 91-134
    • Yalkowsky, S.H.1    Roseman, T.J.2
  • 8
    • 0021357341 scopus 로고
    • Investigation of solubility relationships of polar semi polar and non-polar drugs in mixed cosolvent systems
    • P. H. Gould, M. Goodman, and P. A. Hanson, Investigation of solubility relationships of polar semi polar and non-polar drugs in mixed cosolvent systems, Int. J. Pharm., 19, 149-159 (1984).
    • (1984) Int. J. Pharm. , vol.19 , pp. 149-159
    • Gould, P.H.1    Goodman, M.2    Hanson, P.A.3
  • 9
    • 0021708578 scopus 로고
    • Solubilization by cosolvents. II. Phenytoin in binary and ternary solvents
    • J. T. Rubino, J. Blanchard, and S. H. Yalkowsky, Solubilization by cosolvents. II. Phenytoin in binary and ternary solvents, J. Parenter. Sci. Technol., 38, 215 (1984).
    • (1984) J. Parenter. Sci. Technol. , vol.38 , pp. 215
    • Rubino, J.T.1    Blanchard, J.2    Yalkowsky, S.H.3
  • 10
    • 0023614169 scopus 로고
    • Parenteral formulation development for the positive inotropic agent RS-82856: Solubility and stability enhancement through complexation and lyophilization
    • G. C. Visor, L. Lin, E. Benjamin, R. G. Strickley, and L. Gu, Parenteral formulation development for the positive inotropic agent RS-82856: Solubility and stability enhancement through complexation and lyophilization, J. Parenter. Sci. Technol., 41, 120-125 (1987).
    • (1987) J. Parenter. Sci. Technol. , vol.41 , pp. 120-125
    • Visor, G.C.1    Lin, L.2    Benjamin, E.3    Strickley, R.G.4    Gu, L.5
  • 11
    • 0005043708 scopus 로고    scopus 로고
    • Alteration of apparent solubility through complexation
    • S. H. Yalkowsky, ed., Marcel Dekker, New York
    • A. J. Repta, Alteration of apparent solubility through complexation, in Techniques of Solubilization of Drugs (S. H. Yalkowsky, ed.), Marcel Dekker, New York, 1981, pp. 135-157.
    • Techniques of Solubilization of Drugs , vol.1981 , pp. 135-157
    • Repta, A.J.1
  • 12
    • 0021275548 scopus 로고
    • Solubility enhancement of some developmental anti-cancer nucleoside analogs by complexation with nicotinamide
    • J. Truelove, R. Bawarshi-Nassar, N. R. Chen, and A. Hussain, Solubility enhancement of some developmental anti-cancer nucleoside analogs by complexation with nicotinamide, Int. J. Pharm., 19, 17-25 (1984).
    • (1984) Int. J. Pharm. , vol.19 , pp. 17-25
    • Truelove, J.1    Bawarshi-Nassar, R.2    Chen, N.R.3    Hussain, A.4
  • 13
    • 0027245886 scopus 로고
    • Complexation of moricizine with nicotinamide and evaluation of the complexation constants by various methods
    • M. A. Hussain, R. C. Diluccio, and M. B. Maurin, Complexation of moricizine with nicotinamide and evaluation of the complexation constants by various methods, J. Pharm. Sci., 82, 77-79 (1993).
    • (1993) J. Pharm. Sci. , vol.82 , pp. 77-79
    • Hussain, M.A.1    Diluccio, R.C.2    Maurin, M.B.3
  • 14
    • 0025880327 scopus 로고
    • Self-association of nicotinamide in aqueous solution: Mass transport, freezing-point depression, and partition coefficient studies
    • W. N. Charman, C. S. C. Lai, B. C. Finnin, and B. L. Reed, Self-association of nicotinamide in aqueous solution: Mass transport, freezing-point depression, and partition coefficient studies, Pharm. Res., 8(9), 1144-1150 (1991).
    • (1991) Pharm. Res. , vol.8 , Issue.9 , pp. 1144-1150
    • Charman, W.N.1    Lai, C.S.C.2    Finnin, B.C.3    Reed, B.L.4
  • 15
    • 0025731888 scopus 로고
    • Solubility enhancement of some water-insoluble drugs in the presence of nicotinamide and related compounds
    • A. A. Rasool, A. A. Hussain, and L. W. Ditter, Solubility enhancement of some water-insoluble drugs in the presence of nicotinamide and related compounds, J. Pharm. Sci., 80, 387-393 (1991).
    • (1991) J. Pharm. Sci. , vol.80 , pp. 387-393
    • Rasool, A.A.1    Hussain, A.A.2    Ditter, L.W.3
  • 16
    • 0014150026 scopus 로고
    • Effects of electron donors on the photodecomposition of menadione in aqueous solution. I. The interaction between electron donors and menadione in aqueous solution
    • S. Hata, J. Mizuno, and S. Tomioka, Effects of electron donors on the photodecomposition of menadione in aqueous solution. I. The interaction between electron donors and menadione in aqueous solution, Chem. Pharm. Bull., 15, 1791-1795 (1970).
    • (1970) Chem. Pharm. Bull. , vol.15 , pp. 1791-1795
    • Hata, S.1    Mizuno, J.2    Tomioka, S.3
  • 17
    • 0018841351 scopus 로고
    • Rationalization of drug complexation in aqueous solution by use of Huckel molecular orbitals
    • M. B. Fawzi, E. Davison, and M. S. Tute, Rationalization of drug complexation in aqueous solution by use of Huckel molecular orbitals, J. Pharm. Sci., 69, 104-106 (1980).
    • (1980) J. Pharm. Sci. , vol.69 , pp. 104-106
    • Fawzi, M.B.1    Davison, E.2    Tute, M.S.3
  • 18
    • 0016277868 scopus 로고
    • Complexation of theophylline with sodium benzoate: An NMR study
    • A. L. Thakkar and L. G. Tensmeyer, Complexation of theophylline with sodium benzoate: An NMR study, J. Pharm. Sci., 63, 1319-1321 (1974).
    • (1974) J. Pharm. Sci. , vol.63 , pp. 1319-1321
    • Thakkar, A.L.1    Tensmeyer, L.G.2
  • 19
    • 0027068166 scopus 로고
    • Proton nuclear magnetic resonance spectroscopy studies of the inclusion complex of piroxicam with β-cyclodextrin
    • G. Fronza, A. Mele, E. Redenti, and P. Ventura, Proton nuclear magnetic resonance spectroscopy studies of the inclusion complex of piroxicam with β-cyclodextrin, J. Pharm. Sci., 81, 1162-1165 (1992).
    • (1992) J. Pharm. Sci. , vol.81 , pp. 1162-1165
    • Fronza, G.1    Mele, A.2    Redenti, E.3    Ventura, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.