Pharmacokinetic - Pharmacodynamic analysis of changrolin in dogs with arrhythmia

Yaoxue Xuebao

Volumn 31, Issue 9, 1996, Pages 666-670

  Liu, C X ^a   Gu, Y B ^a   Feng, J L ^a   Wei, G L ^a   Xiao, S H ^a   Sun, J L ^a  

^a TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Antiarrhythmia agent; Changrolin; Pharmacodynamics; Pharmacokinetics

Indexed keywords

ANTIARRHYTHMIC AGENT; CHANGROLIN; QUINAZOLINE DERIVATIVE;

ANIMAL; ARTICLE; DOG; ELECTROCARDIOGRAPHY; HEART ARRHYTHMIA; MALE; METABOLISM;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; DOGS; ELECTROCARDIOGRAPHY; MALE; QUINAZOLINES;

EID: 0030308475     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Coordination changrolin research group. Changrolin, a new antiarrhythmic drug. Chin Med J, 1978, 58: 84
2. Li LQ, Qu X, Wang ZM et al. Studies on a new antiarrhythmic drug, changrolin. Sci Sin, 1979, 22:1220
3. Zeng YL, Yi QC, Gu HM et al. Physiological disposition of changrolin. Acta Pharmacol Sin, 1981, 2:177
4. Chen WZ, Wang CG, Yang XY et al. Clinical pharmacokinetics of anti-arrhythmic agent changrolin. Acta Pharm Sin, 1985, 20:505
5. Xu JM, Yin XL, Chen YM et al. Plasma drug concentration and function in arrhythmic patients during continuous infusion of changrolin. Acta Pharmacol Sin, 1987, 8:227
6. Harris AS. Delayed development of ventricular ectopic rhythm following experimental coronary occlusion. Circulation, 1950, 1:1318
7. Mathematic Pharmacological Committee of Chinese Pharmacology Association. Practice Pharmacokinetic Program. 1987
8. Colburn WA. Simultaneous pharmacokinetic and pharmacodynamic modeling. J Pharmacokinet Biopharm, 1981, 9:367