Hematopoietic differentiation of embryonic stem cells: An in vitro model to study gene regulation during megakaryocytopoiesis

Stem Cells

Volumn 14, Issue SUPPL. 1, 1996, Pages 194-199

  Uzan, Georges ^a   Prandini, Marie Hélène ^a   Rosa, Jean Philippe ^a   Berthier, Rolande ^a  

^a CEA GRENOBLE   (France)

Author keywords

Embryonic stem cells; Hematopoietic growth factors; Megakaryocyte; MS 5 stromal cell line

Indexed keywords

ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 3; INTERLEUKIN 6; STEM CELL FACTOR;

ANIMAL; ARTICLE; CELL LINEAGE; COCULTURE; CULTURE TECHNIQUE; CYTOLOGY; EMBRYO; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; MEGAKARYOCYTE; METABOLISM; METHODOLOGY; MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; TIME;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINEAGE; COCULTURE TECHNIQUES; EMBRYO; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-11; INTERLEUKIN-3; INTERLEUKIN-6; MEGAKARYOCYTES; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELL FACTOR; STROMAL CELLS; TIME FACTORS;

EID: 0030307556     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.5530140725     Document Type: Article

References (30)

1. Uzan G, Prenant M, Prandini MH et al. Tissue-specific expression of the platelet GPIIb gene. J Biol Chem 1991;264:8932-8939.
2. Prandini MH, Uzan G, Martin F et al. Characterization of a specific erythromegakaryocytic enhancer within the glycoprotein IIb promoter. J Biol Chem 1992;267:10370-10374.
3. Ravid K, Doi T, Beeler DL et al. Transcriptional regulation of the rat platelet factor 4 gene: interaction between an enhancer/silencer domain and the GATA site. Mol Cell Biol 1991;11:6116-6127.
4. Hashimoto Y, Ware J. Identification of essential GATA and Ets binding motifs within the promoter of the platelet glycoprotein Ib gene. J Biol Chem 1995;270:24532-24539.
5. Fong AM, Santoro SA. Transcriptional regulation of αIIb integrin gene during megakaryocytic differentiation of K562 cells: role of a silencer element. J Biol Chem 1994;269:18441-18447.
6. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryo. Nature 1981;292:154-156.
7. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cell. Proc Natl Acad Sci USA 1981;78:7634-7638.
8. Bradley A. Embryonic stem cells: proliferation and differentiation. Curr Opin Cell Biol 1990;2:1013-1017.
9. Bradley A, Evans M, Kaufman MH et al. Formation of germ-line chimeras from embryo-derived teratocarcinoma cell lines. Nature 1984;309:255-256.
10. Williams RL, Hilton DJ, Pease S et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 1988;336:684-686.
11. Doetschman TC, Eistetter H, Katz M et al. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol 1985;87:27-45.
12. Lindenbaum MH, Grosveld F. An in vitro globin gene switching model based on differentiated embryonic stem cells. Genes Dev 1990;4:2075-2085.
13. Wiles MV, Keller G. Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture. Development 1991;111:2559-2567.
14. Schmitt RM, Bruyns E, Snodgrass HR. Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression. Genes Dev 1991;5:728-740.
15. Burkert UR, von Ruden T, Wagner EF. Early fetal hematopoietic development from in vitro differentiated embryonic stem cells. New Biol 1991;3:698-708.
16. Lieschke GJ, Dunn AR. Development of functional macrophages from embryonal stem cells in vitro. Exp Hematol 1995;23:328-334.
17. McClanahan T, Dalrymple S, Barkett M et al. Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells. Blood 1993;81:2903-2915.
18. Keller G, Kennedy M, Papayannopoulou T et al. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol 1993;13:473-486.
19. - embryonic stem cells. Genes Dev 1994;8:1184-1197.
20. Bartley TD, Bogenberger J, Hunt P et al. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MPL. Cell 1994;77:1117-1124.
21. Lok S, Kaushansky K, Holly RD et al. Murine thrombopoietin: expression cloning, cDNA sequence and stimulation of platelet production in vivo. Nature 1994;369:565-568.
22. Foster DC, Sprecher CA, Grant FJ et al. Human thrombopoietin: gene structure, cDNA sequence, expression and chromosomal localization. Proc Natl Acad Sci USA 1994;91:13023-13027.
23. Itoh K, Tezuka H, Sakoda H et al. Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Exp Hematol 1989;17:145-153.
24. - progenitor cells in long-term cultures and semisolid assays. Blood 1993;81:2916-2924.
25. Debili N, Croisille L, Breton-Gorius J et al. Identification of a human bipotent erythroid-megakaryocytic (MK) progenitor. Blood 1993;82:2397a.
26. Tsuji K, Lyman SD, Sudo T et al. Enhancement of murine hematopoiesis by synergistic interactions between Steel factor (ligand for c-kit), interleukin-11 and other early acting factors in culture. Blood 1992;79:2855-2860.
27. Bruno E, Cooper RJ, Briddel RA et al. Further examination of the effects of recombinant cytokines on the proliferation of human megakaryocyte progenitor cells. Blood 1991;77:2339-2346.
28. Broudy VC, Lin NL, Kaushansky K. Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood 1995;85:1719-1726.
29. Zeigler FC, de Sauvage F, Widmer HR et al. In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells. Blood 1994;84:4045-4052.
30. Debili N, Wendling F, Cosman D et al. The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets. Blood 1995;85:391-401.