Pentoxifylline and acetylsalicylic acid in a pig random skin-flap model

Journal of Otolaryngology

Volumn 25, Issue 6, 1996, Pages 393-398

  Pratt, Michael F ^a   Williams, Patricia B ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Acetylsalicylic acid; Pentoxifylline; Skin flap model

Indexed keywords

ACETYLSALICYLIC ACID; PENTOXIFYLLINE;

ANIMAL; ARTICLE; AUTOTRANSPLANTATION; COMPARATIVE STUDY; ERYTHROCYTE COUNT; GRAFT SURVIVAL; METHODOLOGY; PLASTIC SURGERY; SWINE; THROMBOCYTE AGGREGATION; ANIMAL EXPERIMENT; ANIMAL MODEL; CONTROLLED STUDY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SKIN FLAP;

ANIMALS; ASPIRIN; ERYTHROCYTE COUNT; GRAFT SURVIVAL; PENTOXIFYLLINE; PLATELET AGGREGATION; RESEARCH DESIGN; SURGICAL FLAPS; SWINE; TRANSPLANTATION, AUTOLOGOUS;

EID: 0030299981     PISSN: 03816605     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Aviado DM, Dettelbach HR. Pharmacology of pentoxifylline a hemorrheologic agent for the treatment of intermittent claudication. Angiology 1984; 35:407-417.
2. Armstrong M, Needham D, Hatchell L, Nuss RS. Effect of pentoxifylline on the flow of polymorphonuclear leukocytes through a model capillary. Angiology 1990; 41:253-261.
3. Barrosa-Aranda J, Schmid-Schonbein GW. Pentoxifylline pretreatment decreases neutrophil activation during endotoxic shock and improves survival. In: Hakin J, Mandell GL, France S, eds. Pentoxifylline and analogues: effects on leukocyte function. Paris: Karger, 1990:97-103.
4. Monteiro DT, Snatmore WP, Nemir P. The influence of pentoxifylline on skin flap survival. Plast Reconstr Surg 1986; 77:277-281.
5. Nemiroff PM. Synergistic effects on pentoxifylline and hyperbaric oxygen on skin flaps. Arch Otolaryngol Head Neck Surg 1988; 114:977-981.
6. Knox RD, Pratt MF, Adkins WY, Flick J. The use of pentoxifylline in a pig random skin flap model. Laryngoscope 1989; 99:582-585.
7. Williams PB, Hankins DB, Layton CT, et al. Long term pretreatment with pentoxifylline increases random skin flap survival. Arch Otolaryngol Head Neck Surg 1994; 120:65-71.
8. Imatani JH, Miller SH, Demuth RJ, Buck DC. Environmental and pharmacologic alterations to ameliorate the no-reflow phenomenon. Surg Forum 1984; 40:599-603.
9. Parker CW. Lipid mediators produced through the lipoxygenase pathway. Annu Rev Immunol 1987; 5:65-84.
10. Reid HL, Bonds AJ, Locke PJ, et al. A simple method for measuring erythrocyte deformability. J Clin Pathol 1976; 29:855-858.
11. Ehrly AM. The effect of pentoxifylline on the flow properties of human blood. Curr Med Res Opin 1978; 5:608-613.
12. Dettelbach HR, Aviado DM. Clinical pharmacology pentoxifylline with special reference to its hemmorheologic effect for the treatment of intermittent claudication. J Clin Pharmacol 1985; 25:86-91.
13. Bochner F, Siebert DM, Rodgers SE, et al. Measurement of aspirin concentrations in portal and systemic blood in pigs: effect on platelet aggregation, thromboxane and prostacyclin production. Thromb Haemost 1989; 61:211-216.