Use of prostaglandin E1 during preparation of platelet concentrates

Transfusion Medicine

Volumn 6, Issue 3, 1996, Pages 249-254

  Hawker, R J ^a   Turner, V S ^a   Mitchell, S G ^a  

^a NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

autologous transfusion; in vivo recovery and survival; platelet activation; platelet concentrate preparation; prostaglandin E1

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTITHROMBOCYTIC AGENT; BETA THROMBOGLOBULIN; CYCLIC AMP; PROSTAGLANDIN E1;

ADULT; AGED; ARTICLE; BLOOD; BLOOD DONOR; CELL SURVIVAL; CENTRIFUGATION; DRUG EFFECT; FEMALE; HUMAN; MALE; MECHANICAL STRESS; METHODOLOGY; SECRETION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTOPHERESIS;

ADENOSINE TRIPHOSPHATE; ADULT; AGED; ALPROSTADIL; BETA-THROMBOGLOBULIN; BLOOD DONORS; BLOOD PLATELETS; CELL SURVIVAL; CENTRIFUGATION; CYCLIC AMP; FEMALE; HUMANS; MALE; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PLATELETPHERESIS; STRESS, MECHANICAL;

EID: 0030299940     PISSN: 09587578     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-3148.1996.tb00076.x     Document Type: Article

References (6)

1. Ashby, B. (1990) Prostaglandin regulation of cyclic AMP metabolism in human platelets. Platelets, 1, 11-20.
2. 1 in preparation and storage of platelet concentrates. Science, 175, 538-539.
3. 1 on harvesting of platelets from refrigerated whole blood. Journal of Laboratory and Clinical Medicine, 83, 304-309.
4. Bode, A.P., Holme, S., Heaton, W.A. & Swanson, M.S. (1994) Sustained elevation of intracellular cyclic 3'-5' adenosine monophosphate is necessary for preservation of platelet integrity during long-term storage at 22 °C. Blood, 83, 1235-1243.
5. Turner, V.S., Hawker, R.J., Mitchell, S.G. & Seymour Mead, A.M. (1994) Paired in vivo and in vitro comparison of apheresis and 'recovered' platelet concentrates stored for 5 days. Journal of Clinical Apheresis, 9, 189-194.
6. Valeri, C.R., Zaroulis, C.G., Rogers, J.C., Handin, R.I. & Marchionni, L.D. (1972) Prostaglandins in the preparation of blood components. Science, 175, 539-542.