-
1
-
-
0028886564
-
Gene therapy for brain tumours
-
Kramm, C. M., Sena-Esteves, M., Barnett F. H., Rainov, N. G., Shuback, D. E., Yu, J. S., Pechan, P. A., Paulus, W., Chiocca, E. A. and Breakefield, X. O. Gene therapy for brain tumours. Brain Pathol. 5, 345-381 (1995).
-
(1995)
Brain Pathol.
, vol.5
, pp. 345-381
-
-
Kramm, C.M.1
Sena-Esteves, M.2
Barnett, F.H.3
Rainov, N.G.4
Shuback, D.E.5
Yu, J.S.6
Pechan, P.A.7
Paulus, W.8
Chiocca, E.A.9
Breakefield, X.O.10
-
2
-
-
0027977970
-
Metabolic suicide genes in gene therapy
-
Mullen, C. M. Metabolic suicide genes in gene therapy. Pharmacol. Ther. 63, 199-207 (1994).
-
(1994)
Pharmacol. Ther.
, vol.63
, pp. 199-207
-
-
Mullen, C.M.1
-
3
-
-
0022485359
-
Tumour chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten, F. L. Tumour chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res. 46, 5276-5281 (1986).
-
(1986)
Cancer Res.
, vol.46
, pp. 5276-5281
-
-
Moolten, F.L.1
-
4
-
-
0025899005
-
Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene
-
Ezzedine, Z. D., Martuza, R. L., Platika, D., Short, M. P., Malick, A., Choi, B. and Breakefield, X. O. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol. 3, 608-614 (1991).
-
(1991)
New Biol.
, vol.3
, pp. 608-614
-
-
Ezzedine, Z.D.1
Martuza, R.L.2
Platika, D.3
Short, M.P.4
Malick, A.5
Choi, B.6
Breakefield, X.O.7
-
5
-
-
0026772206
-
In vivo gene transfer with retroviral-producer cell for treatment of experimental brain tumours
-
Culver, K. W., Ram, Z., Wallbridge, S., Ishi, H., Oldfield, E. H. and Blaese, R. M. In vivo gene transfer with retroviral-producer cell for treatment of experimental brain tumours. Science 256, 1550-1552 (1992).
-
(1992)
Science
, vol.256
, pp. 1550-1552
-
-
Culver, K.W.1
Ram, Z.2
Wallbridge, S.3
Ishi, H.4
Oldfield, E.H.5
Blaese, R.M.6
-
6
-
-
0026445469
-
Gene therapy of malignant brain tumours: A rat glioma line bearing the herpes simplex virus thymidine kinase gene and wild type retrovirus kills other tumour cells
-
Takamiya, Y., Short, M. P., Ezzedine, Z. D., Moolten, F. L., Breakefield, X. O. and Martuza, R. L. Gene therapy of malignant brain tumours: a rat glioma line bearing the herpes simplex virus thymidine kinase gene and wild type retrovirus kills other tumour cells. J. Neurosci. Res. 33, 493-503 (1992).
-
(1992)
J. Neurosci. Res.
, vol.33
, pp. 493-503
-
-
Takamiya, Y.1
Short, M.P.2
Ezzedine, Z.D.3
Moolten, F.L.4
Breakefield, X.O.5
Martuza, R.L.6
-
7
-
-
0027531548
-
In situ retroviral-mediated gene transfer for the treatment of brain tumours in rats
-
Ram, Z., Culver, K. W., Wallbridge, S., Blaese, R. M. and Oldfieid, E. H. In situ retroviral-mediated gene transfer for the treatment of brain tumours in rats. Cancer Res. 53, 83-88 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 83-88
-
-
Ram, Z.1
Culver, K.W.2
Wallbridge, S.3
Blaese, R.M.4
Oldfieid, E.H.5
-
8
-
-
0027317796
-
Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumours
-
Ram, Z., Culver, K. W., Wallbridge, S., Frank, J. A., Blaese, R. M. and Oldfieid, E. H. Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumours. J. Neurosurg. 79, 400-407 (1993).
-
(1993)
J. Neurosurg.
, vol.79
, pp. 400-407
-
-
Ram, Z.1
Culver, K.W.2
Wallbridge, S.3
Frank, J.A.4
Blaese, R.M.5
Oldfieid, E.H.6
-
9
-
-
0027217637
-
An experimental model of retrovirus gene therapy for malignant brain tumours
-
Takamiya, Y., Short, M. P., Moolten, F. L., Fleet, C., Breakefield, X. O. and Martuza, R. L. An experimental model of retrovirus gene therapy for malignant brain tumours. J. Neurosurg. 79, 104-110 (1993).
-
(1993)
J. Neurosurg.
, vol.79
, pp. 104-110
-
-
Takamiya, Y.1
Short, M.P.2
Moolten, F.L.3
Fleet, C.4
Breakefield, X.O.5
Martuza, R.L.6
-
10
-
-
0028093426
-
Gene therapy of rat 9L gliosarcoma tumours by transduction with selectable genes does not require drug selection
-
Tapscott, S. J., Miller, A. D., Olsen, J. M., Berger, M. S., Groudine, M. and Spence, A. M. Gene therapy of rat 9L gliosarcoma tumours by transduction with selectable genes does not require drug selection. Proc. Natl Acad. Sci. USA 91, 8185-8189 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 8185-8189
-
-
Tapscott, S.J.1
Miller, A.D.2
Olsen, J.M.3
Berger, M.S.4
Groudine, M.5
Spence, A.M.6
-
11
-
-
0028202066
-
Gene therapy for brain tumours: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
-
Chen, S.-H., Shine, H. D., Goodman, J. C., Grossman, R. G. and Woo, S. L. C. Gene therapy for brain tumours: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc. Natl Acad. Sci. USA 91, 3054-3057 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 3054-3057
-
-
Chen, S.-H.1
Shine, H.D.2
Goodman, J.C.3
Grossman, R.G.4
Woo, S.L.C.5
-
12
-
-
0021025352
-
The biochemistry and mechanism of action of acyclovir
-
Eliort, G. B. The biochemistry and mechanism of action of acyclovir. J. Antimicr. Chemother. 12, 9-17 (1983).
-
(1983)
J. Antimicr. Chemother.
, vol.12
, pp. 9-17
-
-
Eliort, G.B.1
-
13
-
-
0023840835
-
Insertion and extension of acyclic, dideoxy, and ara nucleotides by herpesviridae, human alpha and human beta polymerases. A unique inhibition mechanism for g-(1,3-dihydroxy-2-propoxymethyl)-guanine triphosphate
-
Reid, R., Eng-Chun, M., Eng-Shang, H. and Topal, M. D. Insertion and extension of acyclic, dideoxy, and ara nucleotides by herpesviridae, human alpha and human beta polymerases. A unique inhibition mechanism for g-(1,3-dihydroxy-2-propoxymethyl)-guanine triphosphate. J. Biol. Chem. 263, 3898-3904 (1988).
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 3898-3904
-
-
Reid, R.1
Eng-Chun, M.2
Eng-Shang, H.3
Topal, M.D.4
-
14
-
-
0001062172
-
Clinical Protocols List
-
Clinical Protocols List. Cancer Gene Ther. 2, 225-234 (1995).
-
(1995)
Cancer Gene Ther.
, vol.2
, pp. 225-234
-
-
-
15
-
-
0023736441
-
Quantitation of tumour response to antineoplastic therapy
-
Grossman, S. A. and Burch, P. A. Quantitation of tumour response to antineoplastic therapy. Semin. Oncol. 15, 441-454 (1988).
-
(1988)
Semin. Oncol.
, vol.15
, pp. 441-454
-
-
Grossman, S.A.1
Burch, P.A.2
-
16
-
-
0017711399
-
Criteria for evaluating patients undergoing chemotherapy for malignant brain tumours
-
Levin, V. A., Crafts, D. C., Norman, D. M., Hoffer, P. B., Spire, J. P. and Wilson, C. B. Criteria for evaluating patients undergoing chemotherapy for malignant brain tumours. J. Neurosurg. 47, 329-335 (1977).
-
(1977)
J. Neurosurg.
, vol.47
, pp. 329-335
-
-
Levin, V.A.1
Crafts, D.C.2
Norman, D.M.3
Hoffer, P.B.4
Spire, J.P.5
Wilson, C.B.6
-
17
-
-
0017621492
-
Brain tumours: Criteria of response and definition of recurrence
-
Wilson, C. B., Crafts, D. C. and Levin, V. A. Brain tumours: criteria of response and definition of recurrence. Natl Cancer Inst. Monogr. 46, 197-203 (1977).
-
(1977)
Natl Cancer Inst. Monogr.
, vol.46
, pp. 197-203
-
-
Wilson, C.B.1
Crafts, D.C.2
Levin, V.A.3
-
19
-
-
0022461325
-
31P NMR spectroscopy
-
31P NMR spectroscopy. Radiology 160, 827-830 (1986).
-
(1986)
Radiology
, vol.160
, pp. 827-830
-
-
Naruse, S.1
Horikawa, Y.2
Tanaka, C.3
Higuchi, T.4
Sekimoto, H.5
Ueda, S.6
Hirakawa, K.7
-
20
-
-
0023264971
-
P-31 MR spectroscopy in the evaluation of brain tumour treatment
-
Segebarth, C. M., Baleriaux, D. F., Arnold, D. L., Lutyen, P. R. and den Hollander, F. A. P-31 MR spectroscopy in the evaluation of brain tumour treatment. Radiology 165, 215-219 (1987).
-
(1987)
Radiology
, vol.165
, pp. 215-219
-
-
Segebarth, C.M.1
Baleriaux, D.F.2
Arnold, D.L.3
Lutyen, P.R.4
Den Hollander, F.A.5
-
22
-
-
0023959293
-
31P NMR spectroscopy of subcutaneous 9L gliosarcoma: Effects of tumour growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumour bioenergetics and histology
-
31P NMR spectroscopy of subcutaneous 9L gliosarcoma: effects of tumour growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumour bioenergetics and histology. Cancer Res. 48, 676-681 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 676-681
-
-
Steen, R.G.1
Tamargo, R.J.2
McGovern, K.A.3
Rajan, S.S.4
Brem, H.5
Wehrle, J.P.6
Glickson, J.D.7
-
23
-
-
0024360275
-
31P NMR spectroscopy: A review
-
31P NMR spectroscopy: a review. Cancer Res. 49, 4075-4085 (1989).
-
(1989)
Cancer Res.
, vol.49
, pp. 4075-4085
-
-
Steen, R.G.1
-
24
-
-
0024472642
-
31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: Dose response of spectral changes
-
31P nuclear magnetic resonance spectroscopy of rat 9L gliosarcoma treated with BCNU: dose response of spectral changes. Magn. Reson. Med. 11, 258-266 (1989).
-
(1989)
Magn. Reson. Med.
, vol.11
, pp. 258-266
-
-
Steen, R.G.1
Tamargo, R.J.2
Brem, H.3
Glickson, J.D.4
Wehrle, J.P.5
-
26
-
-
0026922513
-
Studies of human tumours by MRS
-
Negendank, W. Studies of human tumours by MRS. NMR Biomed. 5, 303-324 (1992).
-
(1992)
NMR Biomed.
, vol.5
, pp. 303-324
-
-
Negendank, W.1
-
27
-
-
0019780712
-
Growth and chemotherapeutic response in athymic mice of tumours arising from human glioma-derived cell lines
-
Bullard, D. E., Schold, S. C., Bigner, S. H. and Bigner, D. D. Growth and chemotherapeutic response in athymic mice of tumours arising from human glioma-derived cell lines. J. Neuropathol. Exp. Neurol. 40, 410-427 (1981).
-
(1981)
J. Neuropathol. Exp. Neurol.
, vol.40
, pp. 410-427
-
-
Bullard, D.E.1
Schold, S.C.2
Bigner, S.H.3
Bigner, D.D.4
-
30
-
-
0026922073
-
Phospholipid metabolites as indicators of cancer cell function
-
Ruiz-Cabello, J. and Cohen, J. S. Phospholipid metabolites as indicators of cancer cell function. NMR Biomed. 5, 226-233 (1992).
-
(1992)
NMR Biomed.
, vol.5
, pp. 226-233
-
-
Ruiz-Cabello, J.1
Cohen, J.S.2
-
31
-
-
0028860037
-
'Bystander killing' induces apoptosis and is inhibited by forskolin
-
Samejima, Y. and Meruelo, D. 'Bystander killing' induces apoptosis and is inhibited by forskolin. Gene Ther. 2, 50-58 (1995).
-
(1995)
Gene Ther.
, vol.2
, pp. 50-58
-
-
Samejima, Y.1
Meruelo, D.2
-
32
-
-
0029161615
-
The 'bystander effect': Association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice
-
Colombo, B. M., Benedetti, S., Ottolenghi, S., Mora, M., Pollo, B., Poli, G. and Finocchiaro, G. The 'bystander effect': association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice. Hum. Gene Ther. 6, 763-772 (1995).
-
(1995)
Hum. Gene Ther.
, vol.6
, pp. 763-772
-
-
Colombo, B.M.1
Benedetti, S.2
Ottolenghi, S.3
Mora, M.4
Pollo, B.5
Poli, G.6
Finocchiaro, G.7
-
33
-
-
0027483695
-
The 'bystander effect': Tumour regression when a fraction of the tumour mass is genetically modified
-
Freeman, S. M., Abboud, C. N., Whartenby, K. A., Packman, C. H., Keoplin, D. S., Moolten, F. L and Abraham, G. N. The 'bystander effect': tumour regression when a fraction of the tumour mass is genetically modified. Cancer Res. 53, 5274-5283 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
Packman, C.H.4
Keoplin, D.S.5
Moolten, F.L.6
Abraham, G.N.7
-
35
-
-
0001918396
-
Cell death: A new classification separating apoptosis from necrosis
-
ed. by Bowen, I. D. and Lockshin, R. A.. Chapman and Hall, London
-
Wyllie, A. H. Cell death: a new classification separating apoptosis from necrosis. In Cell Death in Biology and Pathology, ed. by Bowen, I. D. and Lockshin, R. A., pp. 9-34. Chapman and Hall, London (1981).
-
(1981)
Cell Death in Biology and Pathology
, pp. 9-34
-
-
Wyllie, A.H.1
-
36
-
-
0026919666
-
31P MRS observations of tumour energy metabolism
-
31P MRS observations of tumour energy metabolism. NMR Biomed. 5, 279-289 (1992).
-
(1992)
NMR Biomed.
, vol.5
, pp. 279-289
-
-
Tozer, G.M.1
Griffiths, J.R.2
-
37
-
-
0028071271
-
The effect of thymidine kinase transduction and ganciclovir therapy on tumour vasculature and growth of 9L gliomas in rats
-
Ram, Z., Wallbridge, S., Shawker, T., Culver, K. W., Blaese, R. M. and Oldfield, E. H. The effect of thymidine kinase transduction and ganciclovir therapy on tumour vasculature and growth of 9L gliomas in rats. J. Neurosurg. 81, 256-260 (1994).
-
(1994)
J. Neurosurg.
, vol.81
, pp. 256-260
-
-
Ram, Z.1
Wallbridge, S.2
Shawker, T.3
Culver, K.W.4
Blaese, R.M.5
Oldfield, E.H.6
-
38
-
-
0026407974
-
Cellular energetics measured by phosphorous nuclear magnetic resonance spectroscopy are not correlated with chronic nutrient deficiency in multicellular tumour spheroids
-
Freyer, J. P., Schor, P. L., Jarrett, K. A., Neeman, M. and Sillerud, L. O. Cellular energetics measured by phosphorous nuclear magnetic resonance spectroscopy are not correlated with chronic nutrient deficiency in multicellular tumour spheroids. Cancer Res. 51, 3831-3837 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 3831-3837
-
-
Freyer, J.P.1
Schor, P.L.2
Jarrett, K.A.3
Neeman, M.4
Sillerud, L.O.5
-
39
-
-
0342867147
-
Correlation between alterations in phophomonoesters and cellular proliferation during recovery from quiescence in a tumour model
-
Abstr.
-
Freyer, J. P., Linford, H., Lovejoy, V. and Moore, G. H. Correlation between alterations in phophomonoesters and cellular proliferation during recovery from quiescence in a tumour model. 2nd Annual Meeting of the Society for Magnetic Resonance in Medicine. Abstr., p. 451 (1994).
-
(1994)
2nd Annual Meeting of the Society for Magnetic Resonance in Medicine
, pp. 451
-
-
Freyer, J.P.1
Linford, H.2
Lovejoy, V.3
Moore, G.H.4
-
40
-
-
0025953742
-
The phosphocholine and glycerophosphocholine content of and oestrogen-sensitive rat mammary tumour correlates strongly with growth rate
-
Smith, T. A. D., Eccles, S., Ormerod, M. G., Tombs, A. J., Titley, J. C. and Leach, M. O. The phosphocholine and glycerophosphocholine content of and oestrogen-sensitive rat mammary tumour correlates strongly with growth rate. Br J. Cancer 64, 821-826 (1991).
-
(1991)
Br J. Cancer
, vol.64
, pp. 821-826
-
-
Smith, T.A.D.1
Eccles, S.2
Ormerod, M.G.3
Tombs, A.J.4
Titley, J.C.5
Leach, M.O.6
-
41
-
-
0028168861
-
31P NMR analysis of phosphocholine metabolism in rat glioma cells
-
31P NMR analysis of phosphocholine metabolism in rat glioma cells. Magn. Res. Med. 32, 310-318 (1994).
-
(1994)
Magn. Res. Med.
, vol.32
, pp. 310-318
-
-
Gilles, R.J.1
Barry, J.A.2
Ross, B.D.3
|