Contribution of Na+/Ca2+ exchanger in maintaining [Ca2+]c at a stable state in rat pancreatic islets

Japanese Journal of Physiology

Volumn 46, Issue 6, 1996, Pages 473-480

  Yoshihashi, Kazutaka ^a   Shibuya, Izumi ^b   Kanno, Tomio ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Cytosolic Ca2+ concentration; Fura 2; Islets of Langerhans; Microfluorimetry

Indexed keywords

1 (2 (3 (4 METHOXYPHENYL)PROPOXY) 4 METHOXYPHENYLETHYL) 1H IMIDAZOLE; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CARRIER PROTEIN; ENZYME INHIBITOR; FLUORESCENT DYE; FURA 2; IMIDAZOLE DERIVATIVE; NICKEL; NIFEDIPINE; OUABAIN; SODIUM; SODIUM CALCIUM EXCHANGE PROTEIN; 1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; MEGLUMINE;

ANIMAL; ARTICLE; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; ELECTROCHEMISTRY; IN VITRO STUDY; ION TRANSPORT; KINETICS; MALE; METABOLISM; PANCREAS ISLET; PERFUSION; RAT; SPRAGUE DAWLEY RAT; ANIMAL CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; INSULIN RELEASE; MICROFLUOROMETRY; NONHUMAN; PANCREAS ISLET CELL; SODIUM CALCIUM EXCHANGE; SODIUM TRANSPORT;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CARRIER PROTEINS; CYTOSOL; ELECTROCHEMISTRY; ENZYME INHIBITORS; FLUORESCENT DYES; FURA-2; IMIDAZOLES; ION TRANSPORT; ISLETS OF LANGERHANS; KINETICS; MALE; NA(+)-K(+)-EXCHANGING ATPASE; NICKEL; NIFEDIPINE; OUABAIN; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 0030299041     PISSN: 0021521X     EISSN: None     Source Type: Journal    
DOI: 10.2170/jjphysiol.46.473     Document Type: Article

References (32)

1. 2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion. Physiol Rev 67: 1185-1248, 1987
2. Wollheim CB and Sharp GWG: Regulation of insulin release by calcium. Physiol Rev 61: 914-973, 1981
3. Herchuelz A and Plasman P-O: Sodium-calcium exchange in the pancreatic B cell. Ann NY Acad Sci 639: 642-656, 1991
4. Donatsch P, Lowe DA, Richardson BP, and Taylor P: The functional significance of sodium channels in pancreatic beta-cell membranes. J Physiol (Lond) 267: 357-376, 1977
5. Plasman P-O, Lebrun P, and Herchuelz A: Characterization of the process of sodium-calcium exchange in pancreatic islet cells. Am J Physiol 259: E844-E850, 1990
6. Herchuelz A, Sener A, and Malaisse WJ: Regulation of calcium fluxes in rat pancreatic islets: Calcium extrusion by sodium/calcium countertransport. J Membr Biol 57: 1-12, 1980
7. + removal. Biochem Med 24: 143-152, 1980
8. Herchuelz A and Lebrun P: A role for Na/Ca exchange in the pancreatic B cell Studies with thapsigargin and caffeine. Biochem Pharmacol 45: 7-11, 1993
9. 2+ concentration in mouse pancreatic β-cells. Mechanism of periodicity of spike-bursts Jpn J Physiol 44: 283-293, 1994
10. Lacy PE and Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16: 35-39, 1967
11. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260 3440-3450, 1985
12. Kass GEN, Llopis J, Chow SC, Duddy SK, and Orrenius S: Receptor-operated calcium influx in rat hepatocytes. Identification and characterization using manganese. J Biol Chem 265: 17486-17492, 1990
13. 2+ of agonist-stimulated divalent cation entry from the refilling of the agonist-sensitive intracellular pool J Biol Chem 265: 678-684, 1990
14. 2+, diphenylamine-2-carboxylate, and glucose metabolism. J Biol Chem 269: 17095-17103, 1994
15. Bean BP: Classes of calcium channels in vertebrate cells. Annu Rev Physiol 51: 367-384, 1989
16. Nowycky MC, Fox A, and Tsien RW: Three types of neuronal calcium channels with different calcium antagonist sensitivity. Nature 316: 440-443, 1985
17. ++ channel blockers on energy level and stimulated insulin secretion in isolated rat islets of Langerhans. J Pharmacol Exp Ther 264: 35-40, 1993
18. Merritt JE, Armstrong WP, Benham CD, Hallam TJ, Jacob R, Jaxa-Chamiec A, Leigh BK, McCarthy SA, Moores KE, and Rinks TJ: SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J 271 515-522, 1990
19. Lytton J, Westlin M, and Hanley MR. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 266: 17067-17071, 1991
20. Takemura H, Hughes AR, Thastrup O, and Putney JW Jr: Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. J Biol Chem 264: 12266-12271, 1989
21. 2+-ATPase inhibitor, thapsigargin. Agents Actions 29: 8-15, 1990
22. 1 rise in stimulus-secretion coupling in rat pancreatic islets. Biol Signals 5: 30-43, 1996
23. 2- exchange as a major calcium influx pathway in kidney cells. J Biol Chem 260: 14998-15007, 1985
24. Blaustein MP and Hodgkin AL: The effect of cyanide on the efflux of calcium from squid axons. J Physiol (Lond) 200: 497-527, 1969
25. Mullins LJ: The generation of electric currents in cardiac fibers by Na/Ca exchange. Am J Physiol 233: C103-C110, 1979
26. + in pancreatic β-cells Biochim Biophys Acta 1265: 209-212, 1995
27. Henquin JC and Meissner HP: The electrogenic sodium-potassium pump of mouse pancreatic B-cells. J Physiol (Lond) 332: 529-552, 1982
28. Akiyoshi M, Kakei M, Nakazaki M, and Tanaka H: A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic β-cells. Am J Physiol 268. E185-E193, 1995
29. Eisner DA and Lederer WJ: Na-Ca exchange: Stoichiometry and electrogenicity. Am J Physiol 248. C189-C202, 1985
30. 2+. Am J Physiol 252: C499-C504, 1987
31. Reeves JP and Hale CC: The stoichiometry of the cardiac sodium-calcium exchange system. J Biol Chem 259. 7733-7739, 1984
32. 2+ exchange in plasma membrane vesicles from a glucose-responsive insulinoma. Cell Calcium 13: 1-8, 1992