Induction of lymphomonocyte activation by HIV-1 glycoprotein gp120. Possible role in AIDS pathogenesis

Journal of Biological Regulators and Homeostatic Agents

Volumn 10, Issue 4, 1996, Pages 83-91

  Capobianchi, M R ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Istituto di Virologia   (Italy)

Author keywords

Cytokines; gp120; HIV; Lymphomonocyte activation

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS;

GLYCOPROTEIN GP 120; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON; ALPHA INTERFERON; BETA 2 MICROGLOBULIN; CALCIUM ION; CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; CD71 ANTIGEN; CELL MEMBRANE PROTEIN; CYTOKINE; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; INOSITOL TRISPHOSPHATE; INTERCELLULAR ADHESION MOLECULE 2; INTERCELLULAR ADHESION MOLECULE 3; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; NEOPTERIN; TUMOR NECROSIS FACTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; BIOSYNTHESIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; REVIEW; ANTIGEN PRESENTING CELL; APOPTOSIS; B LYMPHOCYTE ACTIVATION; CALCIUM CELL LEVEL; CELL FUNCTION; CELL PROLIFERATION; CLONAL ANERGY; CYTOTOXICITY; DISEASE COURSE; DNA SYNTHESIS; ENDOTHELIUM CELL; HELPER CELL; IMMUNE SYSTEM; IMMUNOPATHOGENESIS; LYMPHOCYTE; MONOCYTE; MONONUCLEAR CELL; NEUTROPHIL CHEMOTAXIS; T LYMPHOCYTE ACTIVATION; VIRUS ENVELOPE; VIRUS REPLICATION; VIRUS TRANSMISSION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERONS; LYMPHOCYTE ACTIVATION;

EID: 0030298912     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (64)

1. Pantaleo G, Cohen O, Graziosi C, et al. Immunopathogenesis of human immunodeficiency virus infection. In: De Vita VT, Hellman S, Rosenberg SA, eds. AIDS: biology, diagnosis, treatment and prevention. Fourth Edition. New York: Lippincott-Raven 1997; 75.
2. Romagnani S. Human TH1 and TH2 subsets: doubt no more. Immunol Today 1991; 12: 256.
3. Clerici M, Shearer GM. A Th1-Th2 switch is a critical step in the etiology of HIV infection. Immunol Today 1993; 14: 107.
4. Graziosi C, Pantaleo G, Gantt KR, et al. Lack of evidence for dichotomy of Th1 and Th2 predominance in HIV-infected individuals. Science 1994; 265: 248.
5. Maggi E, Mazzetti M, Ravina A, et al. Ability to promote a Th1 to Th0 shift and to replicate preferentially in Th2 and Th0 cells. Science 1994; 265: 244.
6. Mcyaard L, Otto SA, Keet IP, Van Lier RAW, Miedema F. Changes in cytokine secretion patterns of CD4- T-cell clones in human immunodeficiency virus infection. Blood 1994; 84: 4262.
7. Autran B, Leqac E, Blanc C, Debre P. A Th0/Th2-like function of CD4+CD7-T helper cells from normal donors and HIV infected patients. J Immunol 1995; 154: 1408.
8. Dolci A, Serra C, Arca MV, et al. Mutual interactions between HIV-1 and cytokines in adherent cells during acute infection. Arch Virol 1994; 134: 157.
9. Tornatore NC, Nath A, Amemya K, Major E. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. J Virol 1991; 65: 6094
10. Folks TM, Justement, Kinter A, Dinarello CA, Fauci AS. Cytokine-induced expression of HIV in a chronically infected promonocyte cell line. Science 1987; 238: 800.
11. Folks TM, Clouse KA, Justement J, et al. Tumor necrosis factor induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc Natl Acad Sci USA 1989; 86: 2365
12. Koyanagi Y, O'Brien WA, Zhao JQ, Golde DW, Gasson JC, Chen ISY. Cytokines alter production of HIV-1 from primary mononuclear phagocytes. Science 1988; 241: 1673.
13. Kootstra NA, Van'T Wout AB, Huisman HG, Miedema F, Schnitemaker H. Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages. J Virol 1994; 68: 6967.
14. Weissmann D, Poli G, Fauci AS. Interleukin-10 blocks HIV-1 replication in macrophages by inhibiting the autocrine loop of TNF-alpha and IL-6 induction of virus. AIDS Res Hum Retroviruses 1994; 10: 1199.
15. Dolei A, Fattorossi A, D'Amelio R, Aiuti F, Dianzani F. Direct and cell-mediated effects of interferon-alpha and -gamma on cells chronically infected with HTLV-III. J Interferon Res 1986; 6: 543.
16. Macé K, Dodon MD, Gazzolo L. Restriction of HIV-1 replication in promonocytic cells: a role for IFN-alpha. Virology 1988; 168: 399.
17. Pitha PM. Multiple effects of interferon on the replication of human immunodeficiency virus type 1. Antiv Res 1994; 24: 205.
18. Sperber SJ, Gocke DJ, Haberzettl C, Kuk R, Schwartz B, Petska S Anti-HIV-1 activity of recombinant and hybrid species of interferon alpha. J Interferon Res 1992; 12: 363.
19. Poli G, Biswas P, Faucy A. Interferons in the pathogenesis and treatment of human immunodeficiency virus infection. Antiv Res 1994; 24: 221.
20. Wells DE, Chatterjee S, Mulligan MJ, Compans RW. Inhibition of human immunodeficiency virus type 1-induced cell fusion by recombinant human interferons. J Virol 1991; 65: 6325.
21. Hartshorn K, Neumeyer D, Vogt M, Schooley RT, Hirsh MS. Activity of interferons alpha, beta, and gamma against human immunodeficiency virus replication in vitro. AIDS Res Hum Retroviruses 1987; 3: 125.
22. Poli G, Orenstein JM, Kinter A, Folks TM, Fauci AS. Interferon alpha, but not AZT suppresses HIV expression in chronically infected cell lines. Science 1989; 244: 575.
23. Gessani S, Puddu P, Varano B, et al. Induction of beta interferon by human immunodeficiency virus type 1 and its gp 120 protein in human monocytes-macrophages: role of beta interferon in restriction of virus replication. J Virol 1994; 68: 1983.
24. Meyelan PR, Guatelli JC, Munis JR, Richman DD. Kornbluth RS. Mechanisms for the inhibition of HIV replication by interferons-alpha, -beta, and -gamma in primary human macrophages. Virology 1993: 138.
25. Dubrueil M, Sportza L, D'Addario M, et al. Inhibition of HIV-1 transmission by interferon and 3'-azido-3'-deoxythymidine during de novo infection of promonocytic cells. Virology 1990; 179: 388.
26. Gendelman HF, Baca LM, Turpin JA, et al. Restriction of HIV replication in infected T cells and monocytes by interferonalpha. AIDS Res Hum Retroviruses 1990; 6: 1045.
27. Biswas P, Poli G, Kinter AL, et al. Interferon-gamma induces the expression of human immunodeficiency virus in persistently infected promonocytic cells (U1) and redirects the production of virions to intracytoplasmic vacuoles in phorbol myristate acetate-differentiated U1 cells. J Exp Med 1992, 176: 739.
28. Degre M, Beck S, Rollag H. Interferon gamma may enhance infection of blood-derived macrophages with HIV-1 in the presence of HIV-positive serum. APMIS 1992; 100: 465.
29. Banda NK, Bernier J, Kurahara DK, et al. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J Exp Med 1992; 176: 1099.
30. Ameisen JC, Capron A. Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis. Immunol Today 1991; 12: 102.
31. Miedema F, Petit AJ, Terpstra FG, et al. Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men: HIV affects the immune system before CD4+ T helper cell depletion occurs. J Clin Invest 1988; 82: 1908.
32. Bour S, Geleziunas R, Wainberg MA. The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV infection. Microbiol Rev 1995; 59: 63.
33. Chirmule N, Phawa S. Envelope glycoprotein of human immunodeficiency virus type 1: profound influences on immune functions. Microbiol Rev 1996; 60: 386.
34. Capobianchi MR, De Marco F, Di Marco P, Dianzani F. Acidlabile human interferon alpha production by peripheral blood mononuclear cells stimulated by HIV-infected cells. Arch Virol 1988; 99: 9.
35. Capobiancht MR, Ankel H, Ameglio F, et al. Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer. AIDS Res Hum Retroviruses 1992; 8: 575.
36. Capobianchi MR, Ameglio F, Cordiali Fei P, et al. Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120. AIDS Res Hum Retroviruses 1993; 9: 957.
37. Capobianchi MR, Mattana P, Mercuri F, et al. Acid lability is not an intrinsic property of alpha-interferon induced by HIV-infected cells. J Interferon Res 1992; 12: 431.
38. Capobianchi MR, Mattana P, Dianzani F. Potentiation of interferon-alpha in vitro antiviral activity by interferon-gamma is not abrogated by antibody to interferon-gamma. J Interferon Res 1993; 13: 53.
39. De Stefano E, Friedman RM, Friedman-Kien AE, et al. Acidlabile human leukocyte interferon in homosexual men with Kaposi's sarcoma and lymphadenopathy. J Infect Dis 1982; 146: 451.
40. Eyster ME, Goedert JJ, Poon M, Preble OT. Acid labile alpha interferon. A possible preclinical marker for acquired immunodeficiency syndrome in hemofilia. N Engl J Med 1983; 309: 583.
41. Cesario TC, Andrews BS, Martin DA, et al. Interferon in the synovial fluid and serum of patients with rheumatic disease. J Rheumatol 1983; 10; 674.
42. Preble OT, Hook AH, Quinnan GV, et al. Role of interferon in AIDS. Ann NY Acad Sci USA 1984; 437: 64.
43. Arvin AM, Miller JJ, III. Acid labile alpha-interferon in sera and synovial fluids from patients with juvenile arthritis. Arthritis Rheum 1984; 27: 582.
44. Buimovici-Klein E, Lange M, Klein RJ, Grieco MH, Cooper LZ. Long-term follow-up of serum interferon and its acid-stability in a group of homosexual men. AIDS Res 1986; 2: 99.
45. Capobianchi MR, Malavasi F, Mattana P, Mercuri D, Dianzani F. Membrane interaction involved in the induction of acid labile interferon alpha. J Biol Regulators Homeostatic Agents 1990; 4: 19.
46. Francis ML, Meltzer MS. Induction of IFN-alpha by HIV-1 in monocytes-enriched PBM requires gp120-CD4 interaction but not virus replication. J Immunol 1993; 151: 2208.
47. Ankel H, Capobianchi MR, Castilletti C, Dianzani F. Interferon induction by HIV glycoprotein 120: role of V3 loop. Virology 1994; 205: 34.
48. Ankel H, Capobianchi MR, Frezza F, Castilletti C, Dianzani F. Interferon induction by HIV-infected cells: a possible role of sulfatides or related glycolipids. Virology 1996; 221: 113.
49. Svensson H, Johannisson A, Nikkila T, Aim G, Cederblad B. The surface phenotype of human natural interferon-alpha producing cells as determined by flow cytometry. Scand J Immunol 1996; 44: 164.
50. Ferbas JJ, Toso JF, Logar AJ, Navratil JS, Rinaldo CR Jr. CD4+ blood dendritic cells are potent producers of INF-alpha in response to HIV-1 infection. J Immunol 1994; 152: 4649.
51. Fais S, Capobianchi MR, Abbate I, et al. Unidirectional budding of HIV-1 at the site of the cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein. AIDS 1995; 9: 329.
52. Abbate I, Capobianchi MR, Fais S, et al. Host cell antigenic profile acquired by HIV-1 is a marker of its cellular origin. Arch Virol 1995; 140: 1849.
53. Capobianchi MR, Fais S, Castilletti C, et al. A simple and reliable method to detect cell membrane proteins on infectious human immunodeficiency virus-1 particles. J Infect Dis 1994; 169: 866.
54. Dianzani F, Scheglovitova O, Gentile M, et al. Interferon gamma stimulates cell-mediated transmission of HIV-type 1 from abortively infected endothelial cells. AIDS Res Hum Retroviruses 1996; 12: 621.
55. Capobianchi MR, Serra C, Abbate I, et al. Treatment of HIV-infected fibroblasts with human leukocyte antigen (HLA)-DR-inductive cytokines leads to infectious virions with newly acquired HLA-DR. AIDS 1994; 8: 1731.
56. Castilletti C, Capobianchi MR, Fais S, et al. HIV type 1 grown on interferon gamma-treated U937 cells shows selective increase in virion-assocaited intercellular adhesion molecule 1 and HLA-DR and enhanced infectivity for CD4-negative cells. AIDS Res Hum Retroviruses 1995; 11: 547.
57. Springer TA. Traffic signals for lymphocytes recirculation and leukocyte migration: the multistep paradigm. Cell 1994; 67: 301.
58. Scheglovitova O, Capobianchi MR, Antonelli G, Guanmu D, Dianzani F. CD-4 positive cells rescue HIV-1 replication from abortively infected human primary endothelial cells. Arch Virol 1995; 140: 951.
59. Dianzani F, Capobianchi MR. HIV infection of endothelial cells. Persp Drug Discovery Design 1996; 5: 61.
60. Hochstein HD, Natarjan W, Farrar WL. The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion. J Immunol 1991; 147: 2892.
61. Ameglio F, Capobianchi M, Castiletti C, et al. Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells. Correlation with the induction of other cytokines. Clin Exp Immunol 1994; 95: 455.
62. Borghi P, Fantuzzi L, Varano B, et al. Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages. J Virol 1995; 69: 1284.
63. Capobianchi MR, Barresi C, Borghi R et al. Human immunodeficiency virus type 1 gp120 stimulates cytomegalovirus replication in monocytes: possible role of endogenous interleukm-8. J Virol 1997; 71: 1591.
64. Castilletti C, Capobinachi MR, Fais S, et al. Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with other cytokines. Biotech 1994; 9: 101.