메뉴 건너뛰기




Volumn 40, Issue 9, 1996, Pages 834-843

The latent inhibition model of schizophrenia: Further validation using the atypical neuroleptic, clozapine

Author keywords

Clozapine; Latent inhibition; Rat; Schizophrenia

Indexed keywords

AMPHETAMINE; CLOZAPINE;

EID: 0030298492     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-3223(95)00573-0     Document Type: Article
Times cited : (88)

References (66)
  • 1
    • 0026572732 scopus 로고
    • Alprazolam as a neuroleptic adjunct in the emergency treatment of schizophrenia
    • Barbee JG, Mancuso D, Freed CR, et al (1992): Alprazolam as a neuroleptic adjunct in the emergency treatment of schizophrenia. Am J Psychiatry 149:506-510.
    • (1992) Am J Psychiatry , vol.149 , pp. 506-510
    • Barbee, J.G.1    Mancuso, D.2    Freed, C.R.3
  • 2
    • 0023814840 scopus 로고
    • Differential performance of acute and chronic schizophrenics in a latent inhibition task
    • Baruch I, Hemsley D, Gray JA (1988): Differential performance of acute and chronic schizophrenics in a latent inhibition task. J Nerv Ment Dis 176:598-606.
    • (1988) J Nerv Ment Dis , vol.176 , pp. 598-606
    • Baruch, I.1    Hemsley, D.2    Gray, J.A.3
  • 3
    • 0027972344 scopus 로고
    • Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia
    • Brier A, Buchanan RW, Kirkpatrick B, et al (1994): Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia. Am J Psychiatry 151:20-26.
    • (1994) Am J Psychiatry , vol.151 , pp. 20-26
    • Brier, A.1    Buchanan, R.W.2    Kirkpatrick, B.3
  • 7
    • 0027523518 scopus 로고
    • The effects of ritanserin, RU 24969 and 8-OH-DPAT on latent inhibition in the rat
    • Cassaday HJ, Hodges H, Gray JA (1993): The effects of ritanserin, RU 24969 and 8-OH-DPAT on latent inhibition in the rat. J Psychopharmacol 77:63-77.
    • (1993) J Psychopharmacol , vol.77 , pp. 63-77
    • Cassaday, H.J.1    Hodges, H.2    Gray, J.A.3
  • 8
    • 0026692851 scopus 로고
    • Serotonin denervation enhances responsiveness of presynaptic dopamine efflux to acute clozapine in nucleus accumbens but not in caudateputamen
    • Chen J, Paredes W, Gardner EL (1992): Serotonin denervation enhances responsiveness of presynaptic dopamine efflux to acute clozapine in nucleus accumbens but not in caudateputamen. Brain Res 582:173-179.
    • (1992) Brain Res , vol.582 , pp. 173-179
    • Chen, J.1    Paredes, W.2    Gardner, E.L.3
  • 9
    • 0021934560 scopus 로고
    • Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons
    • Chiodo LA, Bunney SB (1985): Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons. J Neurosci 5:2539-2544.
    • (1985) J Neurosci , vol.5 , pp. 2539-2544
    • Chiodo, L.A.1    Bunney, S.B.2
  • 10
    • 0023858224 scopus 로고
    • Haloperidol enhancement of latent inhibition: Relation to therapeutic action?
    • Christison GW, Atwater GE, Dunn LA, Kilts CD (1988): Haloperidol enhancement of latent inhibition: Relation to therapeutic action? Biol Psychiatry 23:746-749.
    • (1988) Biol Psychiatry , vol.23 , pp. 746-749
    • Christison, G.W.1    Atwater, G.E.2    Dunn, L.A.3    Kilts, C.D.4
  • 12
    • 0027490544 scopus 로고
    • 2/1C antagonist, and negative symptoms in schizophrenia: A placebo-controlled double-blind trial
    • 2/1C antagonist, and negative symptoms in schizophrenia: A placebo-controlled double-blind trial. Br J Psychiatry 163:451-455.
    • (1993) Br J Psychiatry , vol.163 , pp. 451-455
    • Duinkerke, S.J.1    Botter, P.A.2    Jansen, A.A.I.3
  • 13
    • 0027169250 scopus 로고
    • Effects of antipsychotic drugs on latent inhibition - Sensitivity and specificity of an animal behavioral model of clinical drug action
    • Dunn LA, Atwater GE, Kilts CD (1993): Effects of antipsychotic drugs on latent inhibition - Sensitivity and specificity of an animal behavioral model of clinical drug action. Psychopharmacology 112:315-323.
    • (1993) Psychopharmacology , vol.112 , pp. 315-323
    • Dunn, L.A.1    Atwater, G.E.2    Kilts, C.D.3
  • 14
    • 0026503249 scopus 로고
    • PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients
    • Farde L, Nordström AL (1992): PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients. Br J Psychiatry 160:30-33.
    • (1992) Br J Psychiatry , vol.160 , pp. 30-33
    • Farde, L.1    Nordström, A.L.2
  • 16
    • 0023942678 scopus 로고
    • Long-term attentional deficit in nonhandled males: Possible involvement of the dopaminergic system
    • Feldon J, Weiner I (1988): Long-term attentional deficit in nonhandled males: Possible involvement of the dopaminergic system. Psychopharmacology 95:231-236.
    • (1988) Psychopharmacology , vol.95 , pp. 231-236
    • Feldon, J.1    Weiner, I.2
  • 17
    • 0024508699 scopus 로고
    • Abolition of the acquisition but not the expression of latent inhibition by chlordiazepoxide in rats
    • Feldon J, Weiner I (1989): Abolition of the acquisition but not the expression of latent inhibition by chlordiazepoxide in rats. Pharmacol Biochem Behav 32:123-127.
    • (1989) Pharmacol Biochem Behav , vol.32 , pp. 123-127
    • Feldon, J.1    Weiner, I.2
  • 18
    • 0025911096 scopus 로고
    • The latent inhibition model of schizophrenic attention disorder: Haloperidol and sulpiride enhance rats' ability to ignore irrelevant stimuli
    • Feldon J, Weiner I (1991): The latent inhibition model of schizophrenic attention disorder: Haloperidol and sulpiride enhance rats' ability to ignore irrelevant stimuli. Biol Psychiatry 29:635-646.
    • (1991) Biol Psychiatry , vol.29 , pp. 635-646
    • Feldon, J.1    Weiner, I.2
  • 19
    • 0026055127 scopus 로고
    • New antipsychotics: Classification, efficacy, and adverse effects
    • Gerlach J (1991): New antipsychotics: Classification, efficacy, and adverse effects. Schizophr Bull 17:289-309.
    • (1991) Schizophr Bull , vol.17 , pp. 289-309
    • Gerlach, J.1
  • 20
    • 0028029107 scopus 로고
    • Drug treatment of schizophrenia: Myths and realities
    • Gerlach J, Casey DE (1994): Drug treatment of schizophrenia: Myths and realities. Curr Opin Psychiatry 7:65-70.
    • (1994) Curr Opin Psychiatry , vol.7 , pp. 65-70
    • Gerlach, J.1    Casey, D.E.2
  • 22
    • 0028802824 scopus 로고
    • The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: Implications for schizophrenia
    • Gray JA, Joseph MH, Hemsley DR, et al (1995): The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: Implications for schizophrenia. Behav Brain Res 71:19-31.
    • (1995) Behav Brain Res , vol.71 , pp. 19-31
    • Gray, J.A.1    Joseph, M.H.2    Hemsley, D.R.3
  • 23
    • 0026960330 scopus 로고
    • Abolition of latent inhibition in acute, but not chronic, schizophrenics
    • Gray NS, Hemsley DR, Gray JA (1992a): Abolition of latent inhibition in acute, but not chronic, schizophrenics. Neurol Psychiat Brain Res 1:83-89.
    • (1992) Neurol Psychiat Brain Res , vol.1 , pp. 83-89
    • Gray, N.S.1    Hemsley, D.R.2    Gray, J.A.3
  • 26
    • 0025941570 scopus 로고
    • Clozapine
    • Jann MW (1991): Clozapine. Pharmacotherapy 11:179-195.
    • (1991) Pharmacotherapy , vol.11 , pp. 179-195
    • Jann, M.W.1
  • 27
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic - A double-blind comparison with chlorpromazine
    • Kane J, Honigfeld G, Singer J, Meltzer H (1988): Clozapine for the treatment-resistant schizophrenic - A double-blind comparison with chlorpromazine. Arch Gen Psychiatry 45:789-796.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 28
    • 0028061401 scopus 로고
    • Towards more effective antipsychotic treatment
    • Kane JM, Freeman HL (1994): Towards more effective antipsychotic treatment. Br J Psychiatry 165:22-31.
    • (1994) Br J Psychiatry , vol.165 , pp. 22-31
    • Kane, J.M.1    Freeman, H.L.2
  • 29
    • 0027178496 scopus 로고
    • Psychopharmacologic treatment of schizophrenia
    • Kane JM, Marder SR (1993): Psychopharmacologic treatment of schizophrenia. Schizophr Bull 19:287-302.
    • (1993) Schizophr Bull , vol.19 , pp. 287-302
    • Kane, J.M.1    Marder, S.R.2
  • 30
    • 0028331326 scopus 로고
    • The new atypical antipsychotics
    • Kerwin RW (1994): The new atypical antipsychotics. Br J Psychiatry 164:141-148.
    • (1994) Br J Psychiatry , vol.164 , pp. 141-148
    • Kerwin, R.W.1
  • 31
    • 0027459312 scopus 로고
    • Differential effects of intra-accumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm
    • Killcross AS, Robbins TW (1993): Differential effects of intra-accumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm. Psychopharmacology 110:479-489.
    • (1993) Psychopharmacology , vol.110 , pp. 479-489
    • Killcross, A.S.1    Robbins, T.W.2
  • 32
    • 0028321753 scopus 로고
    • Effects of the neuroleptic alpha-flupenthixol on latent inhibition in aversively-and appetitively-motivated paradigms - Evidence for dopamine-reinforcer interactions
    • Killcross AS, Dickinson A, Robbins TW (1994): Effects of the neuroleptic alpha-flupenthixol on latent inhibition in aversively-and appetitively-motivated paradigms - Evidence for dopamine-reinforcer interactions. Psychopharmacology 115: 196-205.
    • (1994) Psychopharmacology , vol.115 , pp. 196-205
    • Killcross, A.S.1    Dickinson, A.2    Robbins, T.W.3
  • 33
    • 0028221722 scopus 로고
    • Serotonin receptors - Where are they going?
    • Leonard BE (1994): Serotonin receptors - Where are they going? Int Clin Psychopharmacol 9:7-17.
    • (1994) Int Clin Psychopharmacol , vol.9 , pp. 7-17
    • Leonard, B.E.1
  • 35
    • 0015748659 scopus 로고
    • Latent inhibition
    • Lubow RE (1973): Latent inhibition. Psychol Bull 79:398-407.
    • (1973) Psychol Bull , vol.79 , pp. 398-407
    • Lubow, R.E.1
  • 37
    • 0029195545 scopus 로고
    • Latent inhibition in humans: Data, theory, and implications for schizophrenia
    • Lubow RE, Gewirtz JC (1995): Latent inhibition in humans: Data, theory, and implications for schizophrenia. Psychol Bull 117:87-103.
    • (1995) Psychol Bull , vol.117 , pp. 87-103
    • Lubow, R.E.1    Gewirtz, J.C.2
  • 39
    • 33746358592 scopus 로고
    • A theory of attention: Variations in the associability of stimuli with reinforcement
    • Mackintosh NJ (1975): A theory of attention: Variations in the associability of stimuli with reinforcement. Psychol Rev 82:276-298.
    • (1975) Psychol Rev , vol.82 , pp. 276-298
    • Mackintosh, N.J.1
  • 41
    • 0024468417 scopus 로고
    • Clinical studies on the mechanism of action of clozapine: The dopamine-serotonin hypothesis of schizophrenia
    • Meltzer HY (1989): Clinical studies on the mechanism of action of clozapine: The dopamine-serotonin hypothesis of schizophrenia. Psychopharmacology 99:S18-S27.
    • (1989) Psychopharmacology , vol.99
    • Meltzer, H.Y.1
  • 42
    • 0026091799 scopus 로고
    • The mechanism of action of novel antipsychotic drugs
    • Meltzer HY (1991): The mechanism of action of novel antipsychotic drugs. Schizophr Bull 17:263-287.
    • (1991) Schizophr Bull , vol.17 , pp. 263-287
    • Meltzer, H.Y.1
  • 44
    • 0024854809 scopus 로고
    • The ratios of serotonin2 and dopamine2 affinities differentiate atypical and typical antipsychotic drugs
    • Meltzer HY, Matsubara S, Lee JC (1989b): The ratios of serotonin2 and dopamine2 affinities differentiate atypical and typical antipsychotic drugs. Psychopharmacol Bull 25:390-392.
    • (1989) Psychopharmacol Bull , vol.25 , pp. 390-392
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 45
    • 0018826103 scopus 로고
    • Formation of attentional-associative networks in real time: Role of the hippocampus and implications for conditioning
    • Moore JW, Stickney KJ (1980): Formation of attentional-associative networks in real time: Role of the hippocampus and implications for conditioning. Physiol Psychology 8:207-217.
    • (1980) Physiol Psychology , vol.8 , pp. 207-217
    • Moore, J.W.1    Stickney, K.J.2
  • 46
    • 0026659238 scopus 로고
    • [3] antagonist, facilitates latent inhibition in the rat
    • [3] antagonist, facilitates latent inhibition in the rat. Pharmacol Biochem Behav 42:519-522.
    • (1992) Pharmacol Biochem Behav , vol.42 , pp. 519-522
    • Moran, P.M.1    Moser, P.C.2
  • 47
    • 0001012031 scopus 로고
    • Newer and older antipsychotics: A comparative review of appropriate use
    • Mortimer AM (1994): Newer and older antipsychotics: A comparative review of appropriate use. CNS Drugs 2:381-396.
    • (1994) CNS Drugs , vol.2 , pp. 381-396
    • Mortimer, A.M.1
  • 48
    • 0025131910 scopus 로고
    • Specific anatomy, non-specific drugs: The present state of schizophrenia
    • Nutt DJ (1990): Specific anatomy, non-specific drugs: The present state of schizophrenia. J Psychopharmacol 4:171-175.
    • (1990) J Psychopharmacol , vol.4 , pp. 171-175
    • Nutt, D.J.1
  • 49
    • 0027400871 scopus 로고
    • Haloperidol potentiation of latent inhibition in rats: Evidence for a critical role at conditioning rather than pre-exposure
    • Peters SL, Joseph MH (1993): Haloperidol potentiation of latent inhibition in rats: Evidence for a critical role at conditioning rather than pre-exposure. Behav Pharmacol 4:183-186.
    • (1993) Behav Pharmacol , vol.4 , pp. 183-186
    • Peters, S.L.1    Joseph, M.H.2
  • 51
    • 0022372807 scopus 로고
    • Real-time attentional models for classical conditioning and the hippocampus
    • Schmajuk NA, Moore JW (1985): Real-time attentional models for classical conditioning and the hippocampus. Physiol Psychol 13:278-290.
    • (1985) Physiol Psychol , vol.13 , pp. 278-290
    • Schmajuk, N.A.1    Moore, J.W.2
  • 52
    • 0026481115 scopus 로고
    • Dopamine receptor sequences - Therapeutic levels of neuroleptics occupy D2-receptors, clozapine occupies D4
    • Seeman P (1992): Dopamine receptor sequences - Therapeutic levels of neuroleptics occupy D2-receptors, clozapine occupies D4. Neuropsychopharmacology 7:261-284.
    • (1992) Neuropsychopharmacology , vol.7 , pp. 261-284
    • Seeman, P.1
  • 53
    • 0019417114 scopus 로고
    • Disrupted latent inhibition in the rat with chronic amphetamine or haloperidol-induced supersensitivity: Relationship to schizophrenic attention disorder
    • Solomon PR, Crider A, Winkelman JW, Turi A, Kamer RM, Kaplan LJ (1981): Disrupted latent inhibition in the rat with chronic amphetamine or haloperidol-induced supersensitivity: Relationship to schizophrenic attention disorder. Biol Psychiatry 16:519-537.
    • (1981) Biol Psychiatry , vol.16 , pp. 519-537
    • Solomon, P.R.1    Crider, A.2    Winkelman, J.W.3    Turi, A.4    Kamer, R.M.5    Kaplan, L.J.6
  • 54
    • 0027502034 scopus 로고
    • Neuropharmacologic basis for clozapine's unique profile
    • Tandon R, Kane JM (1993): Neuropharmacologic basis for clozapine's unique profile. Arch Gen Psychiatry 50:158-159.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 158-159
    • Tandon, R.1    Kane, J.M.2
  • 56
    • 0026427253 scopus 로고
    • Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
    • van Tol HH, Bunzow JR, Guan HC, et al (1991): Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 350:610-614.
    • (1991) Nature , vol.350 , pp. 610-614
    • Van Tol, H.H.1    Bunzow, J.R.2    Guan, H.C.3
  • 57
    • 0028232277 scopus 로고
    • Antagonism of amphetamine-induced disruption of LI in rats by haloperidol and ondansetron: Implications for a possible antipsychotic action of ondansetron
    • Warburton EC, Joseph MH, Feldon J, Weiner I, Gray JA (1994): Antagonism of amphetamine-induced disruption of LI in rats by haloperidol and ondansetron: Implications for a possible antipsychotic action of ondansetron. Psychopharmacology 114:657-664.
    • (1994) Psychopharmacology , vol.114 , pp. 657-664
    • Warburton, E.C.1    Joseph, M.H.2    Feldon, J.3    Weiner, I.4    Gray, J.A.5
  • 58
    • 0025520950 scopus 로고
    • Neural substrates of latent inhibition: The switching model
    • Weiner I (1990): Neural substrates of latent inhibition: The switching model. Psychol Bull 108:442-461.
    • (1990) Psychol Bull , vol.108 , pp. 442-461
    • Weiner, I.1
  • 59
    • 0023134401 scopus 로고
    • Facilitation of latent inhibition by haloperidol
    • Weiner I, Feldon J (1987): Facilitation of latent inhibition by haloperidol. Psychopharmacology 91:248-253.
    • (1987) Psychopharmacology , vol.91 , pp. 248-253
    • Weiner, I.1    Feldon, J.2
  • 60
    • 0027987944 scopus 로고
    • The latent inhibition model of schizophrenic attention disorder and of antipsychotic drug action: Comment on Dunn, Atwater and Kilts
    • Psychopharmacology, 1993, 112:315-323
    • Weiner I, Feldon J (1994); The latent inhibition model of schizophrenic attention disorder and of antipsychotic drug action: Comment on Dunn, Atwater and Kilts (Psychopharmacology, 1993, 112:315-323). Psychopharmacology 116: 379-380.
    • (1994) Psychopharmacology , vol.116 , pp. 379-380
    • Weiner, I.1    Feldon, J.2
  • 61
    • 0000099393 scopus 로고
    • Chronic amphetamine and latent inhibition
    • Weiner I, Lubow RE, Feldon J (1981): Chronic amphetamine and latent inhibition. Behav Brain Res 2:285-286.
    • (1981) Behav Brain Res , vol.2 , pp. 285-286
    • Weiner, I.1    Lubow, R.E.2    Feldon, J.3
  • 62
    • 0021263575 scopus 로고
    • Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats
    • Weiner I, Lubow RE, Feldon J (1984): Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats. Psychopharmacology 83:194-199.
    • (1984) Psychopharmacology , vol.83 , pp. 194-199
    • Weiner, I.1    Lubow, R.E.2    Feldon, J.3
  • 63
    • 0023117323 scopus 로고
    • Facilitation of the expression but not the acquisition of latent inhibition by haloperidol in rats
    • Weiner I, Feldon J, Katz Y (1987): Facilitation of the expression but not the acquisition of latent inhibition by haloperidol in rats. Pharmacol Biochem Behav 26:241-246.
    • (1987) Pharmacol Biochem Behav , vol.26 , pp. 241-246
    • Weiner, I.1    Feldon, J.2    Katz, Y.3
  • 64
    • 0024159243 scopus 로고
    • Disruption of latent inhibition by acute administration of low doses of amphetamine
    • Weiner I, Lubow RE, Feldon J (1988): Disruption of latent inhibition by acute administration of low doses of amphetamine. Pharmacol Biochem Behav 30:871-878.
    • (1988) Pharmacol Biochem Behav , vol.30 , pp. 871-878
    • Weiner, I.1    Lubow, R.E.2    Feldon, J.3
  • 65
    • 0028352775 scopus 로고
    • The effects of the new antipsychotic, sertindole, on latent inhibition in rats
    • Weiner I, Kidron R, Tarrasch R, Arnt J, Feldon J (1994): The effects of the new antipsychotic, sertindole, on latent inhibition in rats. Behav Pharmacol 5:119-124.
    • (1994) Behav Pharmacol , vol.5 , pp. 119-124
    • Weiner, I.1    Kidron, R.2    Tarrasch, R.3    Arnt, J.4    Feldon, J.5
  • 66
    • 0027189962 scopus 로고
    • Effects of four antipsychotics on punished responding in rats
    • Wiley JL, Compton AD, Porter JH (1993): Effects of four antipsychotics on punished responding in rats. Pharmacol Biochem Behav 45:263-267.
    • (1993) Pharmacol Biochem Behav , vol.45 , pp. 263-267
    • Wiley, J.L.1    Compton, A.D.2    Porter, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.