Characterization of a 30-kDa Borrelia burgdorferi substrate-binding protein homologue

Research in Microbiology

Volumn 147, Issue 9, 1996, Pages 739-751

  Das, S ^a   Shraga, D ^a   Cannon, C ^b   Lam, T T ^a   Feng, S ^c   Brunet, L R ^a   Telford, S R ^a   Barthold, S W ^a   Flavell, R A ^b   Fikrig, E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Section of Immuwbiology   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Borrelia burgdorferi; Lyme disease; OppA homologue; Outer surface protein; p30

Indexed keywords

BINDING PROTEIN; OUTER MEMBRANE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BORRELIA BURGDORFERI; CONTROLLED STUDY; HUMAN; IMMUNOFLUORESCENCE; LYME DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANIMALIA; BORRELIA; BORRELIA BURGDORFERI; MURINAE; NEGIBACTERIA;

EID: 0030298191     PISSN: 09232508     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2508(97)85121-2     Document Type: Article

References (34)

1. Altschul. S.F., Gish, W., Miller, W.. Myers, E.W. & Lipman, D.J. (1990), Basic local alignment search tool. J. Mol. Biol., 215,403-410.
2. Ames, G.F. (1986), Bacterial periplasmic transport systems: structure, mechanism, and evolution. Annu. Rev. Biochem., 55, 397-425.
3. Bcrgstrom, S., Bundoc, V. & Harbour, A.G. (1989), Molecular analysis of linear plasmid-cncoded major surface proteins, OspA and OpsB, of the Lyme discase spirochete Borrelia burgdorferi. Mol. Microbiol., 3, 479-485.
4. Brand, M.E., Riley, B.S., Radolf, J.D. & Norgard, M.V. (1990), Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproleins. Infect. Immun., 58, 983-991.
5. Champion, C.I., Blanco, D.R., Skare, J.T., Haake, D.A., Giladi, M., Foley, D., Miller, J.N. & Lovett, M.A. (1994), A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein : evidence for expression only during infection, infect. Immun., 62, 2653-2661.
6. Craft, J.E., Fischer, O.K., Shimamoto, G.T. & Sleere, A.C. (1986), Antigens of Borrelia burgdorferi recognized during Lyme disease: appearance of a new IgM response and expansion of the IgG response late in the illness. J. Clin. Invest., 78, 934-939.
7. Ferdows, M.S. & Barbour, A.C. (1989), Megabase-sized linear DNA in the Borreiia burgdorferi, the Lyme disease agent. P roc. natl Acad. Sci. USA. 86, 5969-5973.
8. Fikrig, E., Barthold, S.W., Persing, D.H., Sen, X., Kantor, F.S. & Flavell, R.A, (1992a), Roles of OspA, OspB and flagellin in protective immunity to Lyme borrcliosis in the laboratory mouse. Infect. Immun., 60,657-661,
9. Fikrig, E., Huguenel, E., Berland, R., Rann, D., Hardin, J.D. & Flavell, R.A. (1992b), Serologie diagnosis of Lyme disease using recombinanl OspA, OspB and flagcllin. J. Infeci. Dis., 165, 1127-1132.
10. Fikrig, E., Telford III, S.R., Wallich, R., Chen. M., Lobet, Y., Matuschka, F.R., Kimsey, R.B., Ilantor, F.S., Barthold, S.W., Spielman, A. & Flavell, R.A. (1995), Vaccination against Lyme disease caused by diverse Borrelia burgdorferi. J. Exp. Med., 181, 215-221.
11. Fuchs, H., Wallich, R., Simon, M.M. & Kramer, M.D. (1994), The outer surface protein A of the spirochete Borreiia burgdorferi is a plasmin(ogen) receptor. Proc. Natl. Acad. Sei. USA, 91, 12594-12598.
12. Guyer, C.A., Morgan, D.O., Osheroff, N, & Staros, V. (1985), Purification and characterization of a periplasmic oli- opeptide binding protein from Escherichia coli. J. Biol Chem., 260, 10RI2-10818.
13. Higgins, C.E. (1992), ABC transporters: from microorganisms to man, /Inn. Rev. Cell Biol., 8, 67-113.
14. Higgins, C.E. & Ames, G.F. (1981), Two periplasmic proleins which interact wiih a common membrane receptor show extensive hotnology: complete nucleotide sequences. Proc. Natl. Acad. Sci. USA, 78, 6038-6042.
15. Hiles, I.D. & Higgins, C.K (1986), Peptide uptake by Salmonella typhimurium: the periplasmic oligopeptidebinding protein. Eur. J. Biochem., 158, 561-567.
16. Klarsfdd, A.D., Goossens, P.L, & Cossan, p. (1994), Five Listeria monocylogenes genes preferentially expressed in infected mammalian cells : plcA. purH, purD, pyrE and an argininc ABC transporter gene, arpJ. Mol. Microbiol, 13, 585-597.
17. Lam, T.T., Nguyen, T.K., Fikrig, E. & Flavell, R.A. (1994a), A chromosomal Borrelia burgdorferi gene encodes a 22-kilodalton Hpoprotein, P22, that is serologically recognized in Lyme disease. J. Clin. MicrobioL, 32, 876-883.
18. Lam, T.T., Nguyen, T.K., Montgomery, R., Kantor, F.S., Fikrig, E. & Flavell, R.A. (1994b), Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease. Infect. Immun., 62, 290-298.
19. Lampidis, R., Gross, R., Sokolovic, Z.. Goebel, W. & Kreft, J. (1994), The virulence regulator protein of Lisferia ivanovii is highly homologous to PrfA from Listeria monocylogenes and both belong to the CrpFnr family of transcription regulators. Mol. Microbiol 13, 141-151.
20. Nguyen, T.K., Lam, T.T., Barthold, S.W. & Telford III, S.R., Flavell. R.A. & Fikrig, E. (1994), Partial destruction of Borrelia burgdorferi within ticks lhat engorged on OspE- or OspF-immunized mice. Infect. Immun., 62, 2079-2084.
21. Morris, S.J., Carter, C.J., Howell, J.IC. & Baibour, A.C. (1992), Low-passage-associated proteins of Borrelia burgdorferi B31 : characterization and molecular cloning of OspE, a surface exposed, plasmid encoded lipoprolein. Infect. Immun., 60,4662-4672.
22. Padula, S.J., Jimpieri, A., Dins, F., Szczepanski, A. & Ryan, R.W. (1993), Molecular characterization and expression of p23 (OspC) from a North American strain of Borrelia burgdorferi. Infect. Immun., 61, 5097-5105.
23. Paster, B.J.. Dewhirst. F.E., Weisburg, W.G., Torrioff, L.A., Fraser, G.J., Hespell, R.B., Stanton, T.B., Zahlen, L., Mandelco, L. & Woese, C.R. (1991), Phylogenelic analysis of the spirochetes. J. Bacterial., 173, 6101-6109.
24. Perego, M., Higgins, C.F., Pearce, S.R., Gallagher, M.P, & Hoch, I.A. (1991), The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation. Mol. MicrobioL, 5, 173-185.
25. Probert, W.S. & LeFebvre, R.B. (1994), Protection of C4H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kilodalton antigen. Infect. Immun., 62. 1920-1926.
26. Radolf, J.D. (1994). Role of outer membrane architecture in immune evasion by Treponema pallidum and Borrelia burgdorferi. Trends MicrobioL, 2, 307-311.
27. Rasiah, C., Rauer, S., Gassmunn, G.S. & Vogt, A. (1994), Use of a hybrid protein consisting of the variable region of the Barretia burgdorferi flagdlin and part of the 83-kDa protein as antigen for serodiagnosis of Lyme disease.J Clin. Microbiol, 32. 1011-1017.
28. Schwan, T.G., Burgdorfer, W. & Garon, C.F. (1988), Changes in infectivity and plasmid profile of the Lyme disease spirochctt, Borrelia burgdorferi, as a result in vitro cultivation. Infect. Immun., 56, 1831-1836.
29. Scriba, M., Ebrahim, J.S., Schlott, T. & Eiffert, H. (1993), The 39-kilodalton protein of Borrelia burgdorferi: a target for bactericidal human monoclonal antibodies. Infect. Immun., 61, 4523-4526.
30. Sears, J., Fikrig, E., Nakagawa, T., Deponie, K., Marcan-tonio, N., Kantor, F.S. & Ftavell, R.A. (1991), Molecular mapping of OspA-mediated immunity to Lyme borreliosis..J. Immunot., 147. 1995-2000.
31. Simpson, W.J., Schrumpf, M.E. & Schwan, T.G. (1990), Reactivity of human Lyme borreliosis sera with a 39-kilodalton antigen specific to Borrelia burgdorferi. J. Clin. MicrobioL, 28, 1329-1337.
32. Suk, K., Das, S., Sun, W., Jwang, B., Barthold, S.W., Flavell, R.A. & Fikrig, E. (1995), Borrelia burgjorferi genes selectively expressed in the infected host. Proc. Natl. Acad. Sci. USA, 92, 4269-4273.
33. Wallich, R., Simon, M.M., Hofmann. H., Moler, S.E., Schaible. U.E. & Kramer, M.D. (1993), Molecular and imrnunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi. Infect. Immun., 61, 4158-4166.
34. Wilske. B.. Preac-Mursic, V., Gobel, U.B., Graft, B.. Jauris, S., Soutschek, E., Schwab, E. & Zumstein, G. (1993), An OspA serotyping system for Bnrrelia burgdvrferi based on reactivity with monoclonal antibodies and OspA sequence analysis. J. Clin. Microbiol., 31,340-350.