Tropoelastin gene expression in optic nerve heads of normal and glaucomatous subjects

Matrix Biology

Volumn 15, Issue 5, 1996, Pages 323-330

  Pena, Janethe D O ^a   Roy, Sayon ^b   Hernandez, M Rosario ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

Alternative splicing; Astrocytes; Glaucoma; Lamina cribrosa; Tropoelastin

Indexed keywords

ELASTIN; MESSENGER RNA; TROPOELASTIN;

ADOLESCENT; ADULT; AGED; ALTERNATIVE RNA SPLICING; ARTICLE; ASTROCYTE; CELL CULTURE; CELL GROWTH; CHILD; CONTROLLED STUDY; ELASTIC FIBER; EXON; EXTRACELLULAR MATRIX; FETUS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INFANT; MESSENGER RNA SYNTHESIS; OPEN ANGLE GLAUCOMA; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

EID: 0030297710     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(96)90135-3     Document Type: Article

References (29)

1. Anderson D.A. Ultrastructure of human and monkey lamina cribrosa and optic nerve head. Arch. Ophthalmol. 82:1969;800-814.
2. Boyd C.D., Pierce R.A., Schwarzbauer J.E., Doege K., Sandell L.J. Alternate exon usage is a commonly used mechanism for increasing coding diversity within genes coding for extracellular matrix proteins. Matrix. 13:1993;457-469.
3. Burgoyne C.F., Quigley H.A., Thompson H.W., Vitale S., Varma R. Early changes in optic disc compliance and surface position in experimental glaucoma. Ophthalmology. 102:1995;1800-1809.
4. Chomezynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
5. Curran M.E., Atkinson D., Ewart A.K., Morris C.A., Leppert M.F., Keating M.T. The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis. Cell. 73:1993;159-168.
6. Fazio J.J., Olsen D.R., Kauh E.A., Baldwin C.T., Indik Z., Ornstein-Goldstein N., Yeh H., Rosenbloom J., Uitto J. Cloning of full-length elastin cDNAs from a human skin fibroblast recombinant cDNA library:. Further elucidation of alternative splicing, utilizing exon-specific oligonucleotides. J. Invest. Dermatol. 91:1988;458-464.
7. Fazio M., Olsen D., Kuivaniemi H., Chu M., Davidson J., Rosenbloom J., Uitto J. Isolation and characterization of human elastin cDNAs, and age-associated variation in elastin gene expression in cultured skin fibroblasts. Lab. Invest. 58:1988b;270-277.
8. French-Constant C. Alternative splicing of fibronectin-many different proteins but few different functions. Exp. Cell Res. 221:1995;261-271.
9. Hatten M.E., Liem R.K.H., Shelanski M.L., Mason C.A. Astroglia in CNS injury. Glia. 4:1991;233-243.
10. Hayreh S.S. Pathogenesis of optic nerve damage and visual field defects. Heilmann K., Richard K.T. Glaucoma: Conceptions of a Disease. 1978;104-180 W. B. Saunders, Philadelphia.
11. Hernandez M.R., Luo X.X., Igoe F., Neufeld A.H. Extracellular matrix of the human lamina cribrosa. Am. J. Ophthalmol. 104:1987;567-576.
12. Hernandez M.R., Igoe F., Neufeld A.H. Cell culture of the human lamina cribrosa. Invest. Ophthalmol. Vis. Sci. 29:1988;78-89.
13. Hernandez M.R., Andrzejewska W., Neufeld A.H. Changes in the extracellular matrix of the human optic nerve head in primary open-angle glaucoma. Am. J. Ophthalmol. 109:1990;180-188.
14. Hernandez M.R., Yang J., Ye H. Activation of elastin mRNA expression in human optic nerve heads with primary open-angle glaucoma. J. Glaucoma. 3:1994;214-225.
15. Holzenberger M., Levi-Minzi S.A., Herzog C.P., Deak S.B., Robert L., Boyd C.D. Quantitation of tropoelastin mRNA and assessment of alternative splicing in human skin fibroblasts by reverse transcriptase-polymerase chain reaction. PCR Methods and Applications. 3:1993;107-114.
16. Indik Z., Yeh H., Ornstein-Goldstein N., Sheppard P., Anderson N., Rosenbloom J.C., Peltonen L., Rosenbloom J. Alternative splicing of human elastin mRNA indicated by sequence analysis of cloned genonic and complementary DNA. Proc. Natl. Acad. Sci. USA. 84:1987;5680-5684.
17. Indik Z., Yeh H., Ornstein-Goldstein, Kucich U., Abrams W., Rosenbloom J.C., Rosenbloom J. Structure of the elastin gene and alternative splicing of elastin mRNA: Implications for human disease. Am. J. Med. Genet. 34:1989;81-90.
18. Indik Z., Yeh H., Ornstein-Goldstein N., Rosenbloom J. Structure of the elastin gene and alternative splicing of elastin mRNA. Sandell L.J., Boyd C.D. Extracellular Matrix Genes. 1990;221-250 Academic Press, New York.
19. Mecham R.P., Hinek A., Griffin G.L., Senior R.M., Liotta L.A. The elastin receptor shows structural and functional similarities to the 67-kDa tumor cell laminin receptor. J. Biol. Chem. 264:1989;16652-16657.
20. Milewicz D.M., Pyeritz R.E., Crawford E.S., Byers P.H. Marfan syndrome: defective synthesis, secretion, and extracellular matrix formation of fibrillin by cultured dermal fibroblasts. J. Clin. Invest. 89:1992;76-86.
21. Morrison J.C., Jerdan J.A., Dorman M.F., Quigley H.A. Structural proteins on the neonatal and adult lamina cribrosa. Arch. Opthalmol. 107:1989;1220-1224.
22. Müller H.W., Junghans U., Kappler J. Astroglial neurotrophic and neurite-promoting factors. Pharmaceut. Ther. 65:1995;1-18.
23. Parks W.C., Secrist H., Wu L.C., Mecham R.P. Developmental regulation of tropoelastin isoforms. J. Biol. Chem. 263:1988;4416-4423.
24. Parks W.C., Roby J.D., Wu L.C., Grosso L.E. Cellular expression of tropoelastin mRNA splice variants. Matrix. 12:1992;156-162.
25. Pasquali-Ronchetti I., Bressan G.M., Fornieri C., Baccarani-Contri M., Castellani I., Volpin D. Elastin fiber-associated glycosaminoglycans in β-aminoproprionitrile-induced lathyrism. Exp. Mol. Pathol. 40:1984;235-245.
26. Quigley H.A., Hohman R.M., Addicks E.M., Massof R.W., Green W.R. Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma. Am. J. Ophthalmol. 95:1983;673-691.
27. Stenmark K.R., Durmowicz A.G., Roby J.D., Mecham R.P., Parks W.C. Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension. J. Clin. Invest. 93:994;1234-1242.
28. Ye H., Hernandez M.R. Heterogeneity of astrocytes in human optic nerve head. J. Comp. Neurol. 362:1995;441-452.
29. Zeimer R.C., Ogura Y. The relation between glaucomatous damage and optic nerve mechanical compliance. Arch. Ophthalmol. 107:1989;1232-1234.