메뉴 건너뛰기




Volumn 42, Issue 1, 1996, Pages 1-17

Trk receptor alterations in Alzheimer's disease

Author keywords

Astrocyte; Downs syndrome; Hippocampus; Human brain; Neurodegeneration; Neurotrophin; Senile plaque

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN RECEPTOR; MESSENGER RNA; NEUROTROPHIN; PROTEIN TYROSINE KINASE;

EID: 0030297630     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00040-X     Document Type: Article
Times cited : (100)

References (114)
  • 1
    • 0025168085 scopus 로고
    • Brain-derived neurotrophic factor increases survival and differentiated function of rat septal cholinergic neurons in culture
    • [1] Alderson, R.F., Alterman, A.L., Barde, Y. and Lindsay, R.M., Brain-derived neurotrophic factor increases survival and differentiated function of rat septal cholinergic neurons in culture, Neuron, 5 (1990) 297-306.
    • (1990) Neuron , vol.5 , pp. 297-306
    • Alderson, R.F.1    Alterman, A.L.2    Barde, Y.3    Lindsay, R.M.4
  • 3
    • 0028210761 scopus 로고
    • Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: Association with pathology
    • [3] Anderson, A.J., Cummings, B.J. and Cotman, C.W., Increased immunoreactivity for Jun-and Fos-related proteins in Alzheimer's disease: association with pathology, Exp. Neurol., 125 (1994) 286-295.
    • (1994) Exp. Neurol. , vol.125 , pp. 286-295
    • Anderson, A.J.1    Cummings, B.J.2    Cotman, C.W.3
  • 4
    • 0019781601 scopus 로고
    • A unifying hypothesis for the cause of amyotrophic lateral sclerosis, Parkinsonism, and Alzheimer's disease
    • [4] Appel, S.H., A unifying hypothesis for the cause of Amyotrophic lateral sclerosis, Parkinsonism, and Alzheimer's disease, Ann. Neurol., 10 (1981) 499-505.
    • (1981) Ann. Neurol. , vol.10 , pp. 499-505
    • Appel, S.H.1
  • 5
    • 0025663169 scopus 로고
    • Potential neurotrophic factors in the mammalian central nervous system: Functional significance in the developing and aging brain
    • [5] Araujo, D.M., Chabot, J.G. and Quirion, R., Potential neurotrophic factors in the mammalian central nervous system: functional significance in the developing and aging brain, Int. Rev. Neurobiol., 32 (1990) 141-173.
    • (1990) Int. Rev. Neurobiol. , vol.32 , pp. 141-173
    • Araujo, D.M.1    Chabot, J.G.2    Quirion, R.3
  • 6
    • 0026602079 scopus 로고
    • β-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease
    • [6] Araujo, D.M. and Cotman, C.W., β-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease, Brain, 569 (1992) 141-145.
    • (1992) Brain , vol.569 , pp. 141-145
    • Araujo, D.M.1    Cotman, C.W.2
  • 8
    • 0026510312 scopus 로고
    • The nerve growth factor receptor: A multicomponent system that mediates the actions of the neurotrophin family of proteins
    • [8] Barker, P.A. and Murphy, R.A., The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins, Mol. Cell. Biochem., 110 (1992) 1-15.
    • (1992) Mol. Cell. Biochem. , vol.110 , pp. 1-15
    • Barker, P.A.1    Murphy, R.A.2
  • 12
    • 0028916394 scopus 로고
    • Functional interactions of neurotrophins and neurotrophin receptors
    • [12] Bothwell, M., Functional interactions of neurotrophins and neurotrophin receptors, Annu. Rev. Neurosci., 18 (1995) 223-253.
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 223-253
    • Bothwell, M.1
  • 13
    • 0024386288 scopus 로고
    • Neurotrophic agents may exacerbate the pathological cascade of Alzheimer's disease
    • [13] Butcher, L.L. and Woolf, N.J., Neurotrophic agents may exacerbate the pathological cascade of Alzheimer's disease, Neurobiol. Aging, 10 (1989) 557-570.
    • (1989) Neurobiol. Aging , vol.10 , pp. 557-570
    • Butcher, L.L.1    Woolf, N.J.2
  • 14
    • 0028076182 scopus 로고
    • An alternatively splice form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin 3
    • [14] Calry, D.O. and Reichardt, L.F., An alternatively splice form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin 3, Proc. Natl. Acad. Sci. USA, 91 (1994) 11133-11137.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11133-11137
    • Calry, D.O.1    Reichardt, L.F.2
  • 16
    • 0029021457 scopus 로고
    • p75 and Trk: A two-receptor system
    • [16] Chao, M.V. and Hempstead, B.L., p75 and Trk: a two-receptor system, Trends Neurosci., 18 (1995) 321-326.
    • (1995) Trends Neurosci. , vol.18 , pp. 321-326
    • Chao, M.V.1    Hempstead, B.L.2
  • 17
    • 0027999041 scopus 로고
    • Expression of neurotrophins and their receptors in primary astroglial cultures: Induction by cyclic AMP-elevating agents
    • [17] Condorelli, D.F., Dell'Albani, P., Mudo, G., Timmusk, T. and Belluardo, N., Expression of neurotrophins and their receptors in primary astroglial cultures: induction by cyclic AMP-elevating agents, J. Neurochem., 63 (1994) 509-516.
    • (1994) J. Neurochem. , vol.63 , pp. 509-516
    • Condorelli, D.F.1    Dell'Albani, P.2    Mudo, G.3    Timmusk, T.4    Belluardo, N.5
  • 18
    • 0027197191 scopus 로고
    • Detection of NGF-like activity in human brain tissue: Increased levels in Alzheimer's disease
    • [18] Crutcher, K.A., Scott, S.A., Liang, S., Everson, W.V. and Weingartner, J., Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease, J. Neurosci., 13 (1993) 2540-2550.
    • (1993) J. Neurosci. , vol.13 , pp. 2540-2550
    • Crutcher, K.A.1    Scott, S.A.2    Liang, S.3    Everson, W.V.4    Weingartner, J.5
  • 19
    • 0021367326 scopus 로고
    • The anatomy of the CNS cholinergic neurons
    • [19] Cuello, A.C. and Sofroniew, M.V., The anatomy of the CNS cholinergic neurons, Trends Neurosci., 7 (1984) 74-78.
    • (1984) Trends Neurosci. , vol.7 , pp. 74-78
    • Cuello, A.C.1    Sofroniew, M.V.2
  • 20
    • 0027443553 scopus 로고
    • Trophic responses of forebrain cholinergic neurons: A discussion
    • [20] Cuello, C.A., Trophic responses of forebrain cholinergic neurons: a discussion, Prog. Brain Res., 98 (1993) 265-277.
    • (1993) Prog. Brain Res. , vol.98 , pp. 265-277
    • Cuello, C.A.1
  • 22
    • 0028356223 scopus 로고
    • Immediate-early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischaemic injury to young rat brain
    • [22] Dragunow, M., Beilharz, E., Sirimanne, E., Lawlor, P., Williams, C., Bravo, R. and Gluckman, P., Immediate-early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischaemic injury to young rat brain, Mol. Brain Res., 25 (1994) 19-33.
    • (1994) Mol. Brain Res. , vol.25 , pp. 19-33
    • Dragunow, M.1    Beilharz, E.2    Sirimanne, E.3    Lawlor, P.4    Williams, C.5    Bravo, R.6    Gluckman, P.7
  • 23
    • 0029040355 scopus 로고
    • In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes
    • [23] Dragunow, M., Faull, R.L.M., Lawlor, P., Beilharz, E.J., Singleton, K., Walker, E.B. and Mee, E., In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes, NeuroReport, 6 (1995) 1053-1057.
    • (1995) NeuroReport , vol.6 , pp. 1053-1057
    • Dragunow, M.1    Faull, R.L.M.2    Lawlor, P.3    Beilharz, E.J.4    Singleton, K.5    Walker, E.B.6    Mee, E.7
  • 24
    • 0027218098 scopus 로고
    • Neurotrophins and their receptors: Current concepts and implications for neurological disease
    • [24] Eide, F.F., Lowenstein, D.H. and Reichardt, L.F., Neurotrophins and their receptors: current concepts and implications for neurological disease, Exp. Neurol., 121 (1993) 200-214.
    • (1993) Exp. Neurol. , vol.121 , pp. 200-214
    • Eide, F.F.1    Lowenstein, D.H.2    Reichardt, L.F.3
  • 25
    • 0026464676 scopus 로고
    • Cortical transsynaptic activation of tyrosine kinase receptor TrkB messenger RNA expression in rat hippocampus
    • [25] Falkenberg, T., Ernfors, P., Persson, H. and Lindfors, N., Cortical transsynaptic activation of tyrosine kinase receptor TrkB messenger RNA expression in rat hippocampus, Neuroscience, 51 (1992) 883-889.
    • (1992) Neuroscience , vol.51 , pp. 883-889
    • Falkenberg, T.1    Ernfors, P.2    Persson, H.3    Lindfors, N.4
  • 26
    • 0026589735 scopus 로고
    • Astroglia in Alzheimer's disease
    • [26] Frederickson, R.C.A., Astroglia in Alzheimer's disease, Neurobiol. Aging, 13 (1992) 239-253.
    • (1992) Neurobiol. Aging , vol.13 , pp. 239-253
    • Frederickson, R.C.A.1
  • 27
  • 28
    • 0025976048 scopus 로고
    • Recombinant human basic fibroblast growth factor (rhFGF) induces secretion of nerve growth factor (NGF) in cultured rat astroglial cells
    • [28] Fukumoto, H., Kakihana, M. and Suno, M., Recombinant human basic fibroblast growth factor (rhFGF) induces secretion of nerve growth factor (NGF) in cultured rat astroglial cells, Neurosci. Lett., 122 (1991) 221-224.
    • (1991) Neurosci. Lett. , vol.122 , pp. 221-224
    • Fukumoto, H.1    Kakihana, M.2    Suno, M.3
  • 29
    • 0024997223 scopus 로고
    • Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes
    • [29] Gadient, R.A., Cron, K.C. and Otten, U., Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes, Neurosci. Lett., 117 (1990) 335-340.
    • (1990) Neurosci. Lett. , vol.117 , pp. 335-340
    • Gadient, R.A.1    Cron, K.C.2    Otten, U.3
  • 30
    • 0022480016 scopus 로고
    • Time course of the elevation of nerve growth factor (NGF) content in the hippocampus and septum following lesions of the septohippocampal pathway in rats
    • [30] Gasser, U.E., Weskamp, G., Otten, U. and Dravid, A.R., Time course of the elevation of nerve growth factor (NGF) content in the hippocampus and septum following lesions of the septohippocampal pathway in rats, Brain, 376 (1986) 351-356.
    • (1986) Brain , vol.376 , pp. 351-356
    • Gasser, U.E.1    Weskamp, G.2    Otten, U.3    Dravid, A.R.4
  • 31
    • 46149128942 scopus 로고
    • Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease
    • [31] Goedert, M., Fine, A., Hunt, S.P. and Ullrich, A., Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease, Mol. Brain Res., 1 (1986) 85-92.
    • (1986) Mol. Brain Res. , vol.1 , pp. 85-92
    • Goedert, M.1    Fine, A.2    Hunt, S.P.3    Ullrich, A.4
  • 32
    • 0026524588 scopus 로고
    • Basic FGF in adult rat brain: Cellular distribution and response to entorhinal lesion and fimbra-fornix transection
    • [32] Gomez-Pinilla, F., Lee, J.W. and Cotman, C.W., Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbra-fornix transection, J. Neurosci., 12 (1992) 345-355.
    • (1992) J. Neurosci. , vol.12 , pp. 345-355
    • Gomez-Pinilla, F.1    Lee, J.W.2    Cotman, C.W.3
  • 33
    • 0027939697 scopus 로고
    • The low affinity NGF receptor, p75, can collaborate with each of the trks to potentiate functional responses to the neurotrophins
    • [33] Hantzopoulos, P.A., Suri, C., Glass, D.J., Goldfarb, M.P. and Yancopoulos, G.D., The low affinity NGF receptor, p75, can collaborate with each of the trks to potentiate functional responses to the neurotrophins, Neuron, 13 (1994) 187-201.
    • (1994) Neuron , vol.13 , pp. 187-201
    • Hantzopoulos, P.A.1    Suri, C.2    Glass, D.J.3    Goldfarb, M.P.4    Yancopoulos, G.D.5
  • 34
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • [34] Hardy, J.A. and Higgins, G.A., Alzheimer's disease: the amyloid cascade hypothesis, Science, 256 (1992) 184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 35
    • 0020666935 scopus 로고
    • Is Alzheimer's disease caused by lack of nerve growth factor?
    • [35] Hefti, F., Is Alzheimer's disease caused by lack of nerve growth factor? Ann. Neurol., 13 (1983) 109-110.
    • (1983) Ann. Neurol. , vol.13 , pp. 109-110
    • Hefti, F.1
  • 36
    • 0024351750 scopus 로고
    • Localisation of nerve growth factor receptors in the normal human brain and in Alzheimer's disease
    • [36] Hefti, F. and Mash, D.C., Localisation of nerve growth factor receptors in the normal human brain and in Alzheimer's disease, Neurobiol. Aging, 10 (1989) 75-87.
    • (1989) Neurobiol. Aging , vol.10 , pp. 75-87
    • Hefti, F.1    Mash, D.C.2
  • 37
    • 0025641211 scopus 로고
    • Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments
    • [37] Hellweg, R., Fischer, W., Hock, C., Gage, F.H., Bjorklund, A. and Thoenen, H., Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments, Brain Res., 537 (1990) 123-130.
    • (1990) Brain Res. , vol.537 , pp. 123-130
    • Hellweg, R.1    Fischer, W.2    Hock, C.3    Gage, F.H.4    Bjorklund, A.5    Thoenen, H.6
  • 38
    • 0025774207 scopus 로고
    • High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor
    • [38] Hempstead, B.L., Martin-Zanca, D., Kaplan, D.R., Parada, L.F. and Chao, M.V., High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor, Science, 350 (1991) 678-682.
    • (1991) Science , vol.350 , pp. 678-682
    • Hempstead, B.L.1    Martin-Zanca, D.2    Kaplan, D.R.3    Parada, L.F.4    Chao, M.V.5
  • 39
    • 0024807135 scopus 로고
    • NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease
    • [39] Higgins, G.A. and Mufson, E.J., NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease, Exp. Neurol., 106 (1989) 222-236.
    • (1989) Exp. Neurol. , vol.106 , pp. 222-236
    • Higgins, G.A.1    Mufson, E.J.2
  • 40
    • 0029043623 scopus 로고
    • Association of neurotrophin receptor expression and differentiation in human neuroblastoma
    • [40] Hoehner, J.C., Olsen, L., Sandstedt, B., Kaplan, D.R. and Pahlman, S., Association of neurotrophin receptor expression and differentiation in human neuroblastoma, Am. J. Pathol., 147 (1995) 102-113.
    • (1995) Am. J. Pathol. , vol.147 , pp. 102-113
    • Hoehner, J.C.1    Olsen, L.2    Sandstedt, B.3    Kaplan, D.R.4    Pahlman, S.5
  • 41
    • 0028587152 scopus 로고
    • Regional differences in reactive gliosis induced by substrate-bound β-amyloid
    • [41] Hoke, A., Canning, D.R., Malemud, C.J. and Silver, J., Regional differences in reactive gliosis induced by substrate-bound β-amyloid, Exp. Neurol., 130 (1994) 56-66.
    • (1994) Exp. Neurol. , vol.130 , pp. 56-66
    • Hoke, A.1    Canning, D.R.2    Malemud, C.J.3    Silver, J.4
  • 43
    • 0028358877 scopus 로고
    • Neurotrophic factors and their receptors
    • [43] Ip, N.Y. and Yancopoulos, G.D., Neurotrophic factors and their receptors, Ann. Neurol., 35 (1994) S13-S16.
    • (1994) Ann. Neurol. , vol.35
    • Ip, N.Y.1    Yancopoulos, G.D.2
  • 44
    • 0028852525 scopus 로고
    • Interactions between second messenger pathways influence NGF synthesis in mouse primary astrocytes
    • [44] Jehan, F., Neveu, I., Naveilhan, P., Wion, D. and Brachet, P., Interactions between second messenger pathways influence NGF synthesis in mouse primary astrocytes, Brain Res., 672 (1995) 128-136.
    • (1995) Brain Res. , vol.672 , pp. 128-136
    • Jehan, F.1    Neveu, I.2    Naveilhan, P.3    Wion, D.4    Brachet, P.5
  • 45
    • 0028129444 scopus 로고
    • NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients
    • [45] Jette, N., Cole, M.S. and Fahnestock, M., NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients, Mol. Brain Res., 25 (1994) 242-250.
    • (1994) Mol. Brain Res. , vol.25 , pp. 242-250
    • Jette, N.1    Cole, M.S.2    Fahnestock, M.3
  • 46
    • 0028177535 scopus 로고
    • Purification and characterization of a brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) heterodimer
    • [46] Jungbluth, S., Bailey, K. and Barde, Y.A., Purification and characterization of a brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) heterodimer, Eur. J. Biochem., 221 (1994) 677-685.
    • (1994) Eur. J. Biochem. , vol.221 , pp. 677-685
    • Jungbluth, S.1    Bailey, K.2    Barde, Y.A.3
  • 47
    • 0025735392 scopus 로고
    • The trk proto-oncogene product: A signal transducing receptor for nerve growth factor
    • [47] Kaplan, D.R., Hempstead, B.L., Martin-Zanca, D., Chao, M.V. and Parada, L.F., The trk proto-oncogene product: a signal transducing receptor for nerve growth factor, Science, 252 (1991) 554-557.
    • (1991) Science , vol.252 , pp. 554-557
    • Kaplan, D.R.1    Hempstead, B.L.2    Martin-Zanca, D.3    Chao, M.V.4    Parada, L.F.5
  • 48
    • 0025797396 scopus 로고
    • Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF
    • [48] Kaplan, D.R., Martin-Zanca, D. and Parada, L.F., Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF, Nature, 350 (1991) 158-160.
    • (1991) Nature , vol.350 , pp. 158-160
    • Kaplan, D.R.1    Martin-Zanca, D.2    Parada, L.F.3
  • 49
    • 0026726972 scopus 로고
    • Hippocampal nerve growth factor receptor immunoreactivity in patients with Alzheimer's and Parkinson's disease
    • [49] Kerwin, J.M., Morris, C.M., Perry, R.H. and Perry, E.K., Hippocampal nerve growth factor receptor immunoreactivity in patients with Alzheimer's and Parkinson's disease, Neurosci. Lett., 143 (1992) 101-104.
    • (1992) Neurosci. Lett. , vol.143 , pp. 101-104
    • Kerwin, J.M.1    Morris, C.M.2    Perry, R.H.3    Perry, E.K.4
  • 50
    • 0025281397 scopus 로고
    • The trkB tyrosine protein kinase receptor gene codes for a second neurogenic receptor that lacks the catalytic kinase domain
    • [50] Klein, R., Conway, D., Parada, L.F. and Barbacid, M., The trkB tyrosine protein kinase receptor gene codes for a second neurogenic receptor that lacks the catalytic kinase domain, Cell, 61 (1990) 647-656.
    • (1990) Cell , vol.61 , pp. 647-656
    • Klein, R.1    Conway, D.2    Parada, L.F.3    Barbacid, M.4
  • 52
    • 85030272494 scopus 로고
    • trkB, a novel tyrosine kinase receptor expressed during mouse neural development
    • [52] Klein, R., Parada, L.F., Coulier, F. and Barbacid, M., trkB, a novel tyrosine kinase receptor expressed during mouse neural development, EMBO J., 8 (1989) 3071-3079.
    • (1989) EMBO J. , vol.8 , pp. 3071-3079
    • Klein, R.1    Parada, L.F.2    Coulier, F.3    Barbacid, M.4
  • 53
    • 0025780387 scopus 로고
    • Recombinant human nerve growth factor prevents retrograde degeneration of axotomised basal forebrain cholinergic neurons in the rat
    • [53] Koliatsos, V.E., Applegate, M.D., Knusel, B., Junard, E.O., Burton, L.E., Mobley, W.C., Hefti, F. and Price, D., Recombinant human nerve growth factor prevents retrograde degeneration of axotomised basal forebrain cholinergic neurons in the rat, Exp. Neurol., 112 (1991) 161-173.
    • (1991) Exp. Neurol. , vol.112 , pp. 161-173
    • Koliatsos, V.E.1    Applegate, M.D.2    Knusel, B.3    Junard, E.O.4    Burton, L.E.5    Mobley, W.C.6    Hefti, F.7    Price, D.8
  • 54
    • 0026408777 scopus 로고
    • Biological effects of nerve growth factor on lesioned basal forebrain neurons
    • [54] Koliatsos, V.E., Clatterbuck, R.E., Gouras, G.K. and Price, D.L., Biological effects of nerve growth factor on lesioned basal forebrain neurons, Ann. NY Acad. Sci., 640 (1991) 102-109.
    • (1991) Ann. NY Acad. Sci. , vol.640 , pp. 102-109
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Gouras, G.K.3    Price, D.L.4
  • 56
    • 0027375807 scopus 로고
    • Neurotrophic strategies for treating Alzheimer's disease: Lessons from basic neurobiology and animal models
    • [56] Koliatsos, V.E., Price, D.L., Clatterbuck, R.E., Markowska, A.L., Olton, D.S. and Wilcock, B.J., Neurotrophic strategies for treating Alzheimer's disease: lessons from basic neurobiology and animal models, Ann. NY Acad. Sci., 640 (1991) 292-299.
    • (1991) Ann. NY Acad. Sci. , vol.640 , pp. 292-299
    • Koliatsos, V.E.1    Price, D.L.2    Clatterbuck, R.E.3    Markowska, A.L.4    Olton, D.S.5    Wilcock, B.J.6
  • 57
    • 0025730696 scopus 로고
    • Alzheimer plaques and tangles: Advances on both fronts
    • [57] Kosik, K.S., Alzheimer plaques and tangles: advances on both fronts, Trends Neurosci., 14 (1991) 218-219.
    • (1991) Trends Neurosci. , vol.14 , pp. 218-219
    • Kosik, K.S.1
  • 58
    • 0029114162 scopus 로고
    • Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1
    • [58] Lahiri, D.K. and Nall, C., Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1, Mol. Brain Res., 32 (1995) 233-240.
    • (1995) Mol. Brain Res. , vol.32 , pp. 233-240
    • Lahiri, D.K.1    Nall, C.2
  • 59
    • 0027771726 scopus 로고
    • Nerve growth factor pharmacology: Application to the treatment of cholinergic neurodegeneration in Alzheimer's disease
    • [59] Lapchack, P.A., Nerve growth factor pharmacology: application to the treatment of cholinergic neurodegeneration in Alzheimer's disease, Exp. Neurol., 124 (1993) 16-20.
    • (1993) Exp. Neurol. , vol.124 , pp. 16-20
    • Lapchack, P.A.1
  • 60
    • 0025732221 scopus 로고
    • Effect of recombinant human nerve growth factor on presynaptic cholinergic function in rat hippocampal slices following partial septohippocampal lesions: Measures of [H] acetylcholine synthesis, [H] acetylcholine release and choline acetyltransferase activity
    • [60] Lapchak, P.A. and Hefti, F., Effect of recombinant human nerve growth factor on presynaptic cholinergic function in rat hippocampal slices following partial septohippocampal lesions: measures of [H] acetylcholine synthesis, [H] acetylcholine release and choline acetyltransferase activity, Neuroscience, 42 (1991) 639-649.
    • (1991) Neuroscience , vol.42 , pp. 639-649
    • Lapchak, P.A.1    Hefti, F.2
  • 61
    • 0025952994 scopus 로고
    • NGF gene expression in actively growing brain glia
    • [61] Li, B., Yokoyama, M., Dreyfus, C.F. and Black, I.B., NGF gene expression in actively growing brain glia, J. Neurosci., 11 (1991) 318-326.
    • (1991) J. Neurosci. , vol.11 , pp. 318-326
    • Li, B.1    Yokoyama, M.2    Dreyfus, C.F.3    Black, I.B.4
  • 62
    • 0028592625 scopus 로고
    • Neurotrophins and receptors
    • [62] Lindsay, R.M., Neurotrophins and receptors, Prog. Brain Res., 103 (1994) 3-14.
    • (1994) Prog. Brain Res. , vol.103 , pp. 3-14
    • Lindsay, R.M.1
  • 63
    • 0027524957 scopus 로고
    • The neurotrophic hypothesis and the cholinergic basal forebrain projection
    • [63] Lucidi-Phillipi, C.A. and Gage, F.H., The neurotrophic hypothesis and the cholinergic basal forebrain projection, Prog. Brain Res., 98 (1993) 241-249.
    • (1993) Prog. Brain Res. , vol.98 , pp. 241-249
    • Lucidi-Phillipi, C.A.1    Gage, F.H.2
  • 66
    • 0025861679 scopus 로고
    • Is the pattern of nerve cell loss in aging and Alzheimer's disease real, or only apparent, selectivity?
    • [66] Mann, D.M., Is the pattern of nerve cell loss in aging and Alzheimer's disease real, or only apparent, selectivity? Neurobiol. Aging, 12 (1991) 340-343.
    • (1991) Neurobiol. Aging , vol.12 , pp. 340-343
    • Mann, D.M.1
  • 67
    • 0024579524 scopus 로고
    • Molecular and biochemical characterisation of the human trk proto-oncogene
    • [67] Martin-Zanca, D., Mitra, G., Copeland, T. and Barbacid, M., Molecular and biochemical characterisation of the human trk proto-oncogene, Mol. Cell. Biol., 9 (1989) 24-33.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 24-33
    • Martin-Zanca, D.1    Mitra, G.2    Copeland, T.3    Barbacid, M.4
  • 68
    • 0025156782 scopus 로고
    • NGF and Alzheimer's: Hopes and fears
    • [68] Marx, J., NGF and Alzheimer's: hopes and fears, Science, 247 (1990) 408-410.
    • (1990) Science , vol.247 , pp. 408-410
    • Marx, J.1
  • 69
    • 0027367765 scopus 로고
    • β-amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease
    • [69] Mattson, M.P., Barger, S.W., Cheng, B., Lieberburg, I., SmithSwintosky, V.L. and Rydel, R.E., β-amyloid precursor protein metabolites and loss of neuronal calcium homeostasis in Alzheimer's disease, Trends Neurosci., 16 (1993) 409-414.
    • (1993) Trends Neurosci. , vol.16 , pp. 409-414
    • Mattson, M.P.1    Barger, S.W.2    Cheng, B.3    Lieberburg, I.4    Smithswintosky, V.L.5    Rydel, R.E.6
  • 70
    • 0026766860 scopus 로고
    • The nerve growth factor family of receptors
    • [70] Meakin, S.O. and Shooter, E.M., The nerve growth factor family of receptors, Trends Neurosci., 15 (1992) 323-330.
    • (1992) Trends Neurosci. , vol.15 , pp. 323-330
    • Meakin, S.O.1    Shooter, E.M.2
  • 71
    • 0028152717 scopus 로고
    • MacGarvey, u
    • [71] Mecocci, P., MacGarvey, U. and Beal, M.F., Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease, Ann. Neurol., 36 (1994) 747-751.
    • (1994) Ann. Neurol. , vol.36 , pp. 747-751
    • Mecocci, P.1    Beal, M.F.O.D.T.2
  • 73
    • 0027930143 scopus 로고
    • Astrocytes associated with senile plaques possess muscarinic acetylcholine receptors
    • [73] Messamore, E., Bogdanovich, N., Schroder, H. and Winblad, B., Astrocytes associated with senile plaques possess muscarinic acetylcholine receptors, NeuroReport, 5 (1994) 1473-1476.
    • (1994) NeuroReport , vol.5 , pp. 1473-1476
    • Messamore, E.1    Bogdanovich, N.2    Schroder, H.3    Winblad, B.4
  • 74
    • 0026025820 scopus 로고
    • TrkB, a neural receptor protein-tyrosine kinase: Evidence for a full-length and two truncated receptors
    • [74] Middlemas, D.S., Lindberg, R.A. and Hunter, T., TrkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors, Mol. Cell. Biol., 11 (1991) 143-153.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 143-153
    • Middlemas, D.S.1    Lindberg, R.A.2    Hunter, T.3
  • 75
    • 0026663993 scopus 로고
    • The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
    • [75] Milward, E.A., Papadopoulos, R., Fuller, S.J., Moir, R.D., Small, D., Beyreuther, K. and Masters, C.L., The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth, Neuron, 9 (1992) 129-137.
    • (1992) Neuron , vol.9 , pp. 129-137
    • Milward, E.A.1    Papadopoulos, R.2    Fuller, S.J.3    Moir, R.D.4    Small, D.5    Beyreuther, K.6    Masters, C.L.7
  • 77
    • 0001585073 scopus 로고
    • Nerve growth factor increases mRNA levels for the prion protein and the β-amyloid protein precursor in developing hamster brain
    • [77] Mobley, W.C., Neve, R.L., Prusiner, S.B. and McKinley, M.P., Nerve growth factor increases mRNA levels for the prion protein and the β-amyloid protein precursor in developing hamster brain, Proc. Natl. Acad. Sci. USA, 85 (1988) 9811-9815.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9811-9815
    • Mobley, W.C.1    Neve, R.L.2    Prusiner, S.B.3    McKinley, M.P.4
  • 78
    • 0029039162 scopus 로고
    • Nerve growth factor in Alzheimer's disease: Defective retrograde transport to nucleus basalis
    • [78] Mufson, E.J., Conner, J.M. and Kordower, J.H., Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis, NeuroReport, 6 (1995) 1063-1066.
    • (1995) NeuroReport , vol.6 , pp. 1063-1066
    • Mufson, E.J.1    Conner, J.M.2    Kordower, J.H.3
  • 79
    • 0028214892 scopus 로고
    • Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation
    • [79] Mufson, E.J., Conner, J.M., Varon, S. and Kordower, J.H., Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation, J. Comp. Neurol., 341 (1994) 507-519.
    • (1994) J. Comp. Neurol. , vol.341 , pp. 507-519
    • Mufson, E.J.1    Conner, J.M.2    Varon, S.3    Kordower, J.H.4
  • 80
    • 0026571233 scopus 로고
    • Cortical neurons express nerve growth factor receptors in advancing age and Alzheimer's disease
    • [80] Mufson, E.J. and Kordower, J.H., Cortical neurons express nerve growth factor receptors in advancing age and Alzheimer's disease, Proc. Natl. Acad. Sci. USA, 89 (1992) 569-573.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 569-573
    • Mufson, E.J.1    Kordower, J.H.2
  • 82
    • 0028297574 scopus 로고
    • Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease
    • [82] Murray, K.D., Gall, C.M., Jones, E.G. and Isackson, P.J., Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease, Neuroscience, 60 (1994) 37-48.
    • (1994) Neuroscience , vol.60 , pp. 37-48
    • Murray, K.D.1    Gall, C.M.2    Jones, E.G.3    Isackson, P.J.4
  • 83
    • 0027531016 scopus 로고
    • Association between high levels of expression of the trk gene and favourable outcome in human neuroblastoma
    • [83] Nakagawara, A., Arima-Nakagawa, M., Scavarda, N.J., Azar, C.G., Cantor, A.B. and Brodeur, G.M., Association between high levels of expression of the trk gene and favourable outcome in human neuroblastoma, N. Engl. J. Med., 328 (1993) 847-854.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 847-854
    • Nakagawara, A.1    Arima-Nakagawa, M.2    Scavarda, N.J.3    Azar, C.G.4    Cantor, A.B.5    Brodeur, G.M.6
  • 84
    • 0026001992 scopus 로고
    • β-amyloid protein in Alzheimer's disease
    • [84] Nalbantoglu, J., β-amyloid protein in Alzheimer's disease, Can. J. Neurol. Sci., 18 (1991) 424-427.
    • (1991) Can. J. Neurol. Sci. , vol.18 , pp. 424-427
    • Nalbantoglu, J.1
  • 85
    • 0028180405 scopus 로고
    • Active microglia, sick astroglia and Alzheimer type dementia's
    • [85] Nieto-Sampedro, M. and Mora, F., Active microglia, sick astroglia and Alzheimer type dementia's, NeuroReport, 5 (1994) 375-380.
    • (1994) NeuroReport , vol.5 , pp. 375-380
    • Nieto-Sampedro, M.1    Mora, F.2
  • 86
    • 0027745626 scopus 로고
    • NGF and the treatment of Alzheimer's disease
    • [86] Olson, L., NGF and the treatment of Alzheimer's disease, Exp. Neurol., 124 (1993) 5-15.
    • (1993) Exp. Neurol. , vol.124 , pp. 5-15
    • Olson, L.1
  • 87
    • 0028986501 scopus 로고
    • Increased β-amyloid precursor protein expression in astrocytes in the gerbil hippocampus following ischaemia: Association with proliferation of astrocytes
    • [87] Palacios, G., Mengod, G., Tortosa, A., Ferrer, I. and Palacios, J.M., Increased β-amyloid precursor protein expression in astrocytes in the gerbil hippocampus following ischaemia: association with proliferation of astrocytes. Eur. J. Neurosci., 7 (1995) 501-510.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 501-510
    • Palacios, G.1    Mengod, G.2    Tortosa, A.3    Ferrer, I.4    Palacios, J.M.5
  • 88
    • 0025601487 scopus 로고
    • Neural plasticity in aging and Alzheimer's disease: Some selected comments
    • [88] Phelps, C.H., Neural plasticity in aging and Alzheimer's disease: some selected comments, Prog. Brain Res., 86 (1990) 3-9.
    • (1990) Prog. Brain Res. , vol.86 , pp. 3-9
    • Phelps, C.H.1
  • 89
    • 0025993361 scopus 로고
    • BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease
    • [89] Phillips, H.S., Hains, J.M., Armanini, M., Laramee, G.R., Johnson, S.A. and Winslow, J.W., BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease, Neuron, 7 (1991) 695-702.
    • (1991) Neuron , vol.7 , pp. 695-702
    • Phillips, H.S.1    Hains, J.M.2    Armanini, M.3    Laramee, G.R.4    Johnson, S.A.5    Winslow, J.W.6
  • 90
    • 0024990331 scopus 로고
    • Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons
    • [90] Phillips, H.S., Hains, J.M., Laramee, G.R., Rosenthal, A. and Winslow, J.W., Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons, Science, 250 (1990) 290-293.
    • (1990) Science , vol.250 , pp. 290-293
    • Phillips, H.S.1    Hains, J.M.2    Laramee, G.R.3    Rosenthal, A.4    Winslow, J.W.5
  • 91
    • 0028981219 scopus 로고
    • Structure-activity analyses of β-amyloid peptides: Contributions of the β25-35 region to aggregation and neurotoxicity
    • [91] Pike, C.J., Walencewicz-Wasserman, A.J., Kosmoski, J., Cribbs, D.H., Glabe, C.G. and Cotman, C.W., Structure-activity analyses of β-amyloid peptides: contributions of the β25-35 region to aggregation and neurotoxicity, J. Neurochem., 64 (1995) 253-265.
    • (1995) J. Neurochem. , vol.64 , pp. 253-265
    • Pike, C.J.1    Walencewicz-Wasserman, A.J.2    Kosmoski, J.3    Cribbs, D.H.4    Glabe, C.G.5    Cotman, C.W.6
  • 92
    • 0027070863 scopus 로고
    • The involvement of astrocytes and an acute phase response in the amyloid deposition of Alzheimer's disease
    • [92] Potter, H., The involvement of astrocytes and an acute phase response in the amyloid deposition of Alzheimer's disease, Prog. Brain Res., 94 (1992) 447-458.
    • (1992) Prog. Brain Res. , vol.94 , pp. 447-458
    • Potter, H.1
  • 93
    • 0027996904 scopus 로고
    • Expression of the low-affinity nerve growth factor receptor enhances β-amyloid peptide toxicity
    • [93] Rabizadeh, S., Bitler, C.M., Butcher, L.L. and Bredesen, D.E., Expression of the low-affinity nerve growth factor receptor enhances β-amyloid peptide toxicity, Proc. Natl. Acad. Sci. USA, 91 (1994) 10703-10706.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10703-10706
    • Rabizadeh, S.1    Bitler, C.M.2    Butcher, L.L.3    Bredesen, D.E.4
  • 95
    • 0026781306 scopus 로고
    • The role of amyloid β-protein in Alzheimer's disease
    • [95] Regland, B. and Gottfries, C., The role of amyloid β-protein in Alzheimer's disease, Lancet, 340 (1992) 467-468.
    • (1992) Lancet , vol.340 , pp. 467-468
    • Regland, B.1    Gottfries, C.2
  • 97
    • 0028019154 scopus 로고
    • Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS
    • [97] Rylett, R.J. and Williams, L.R., Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS, Trends Neurosci., 17 (1994) 486-489.
    • (1994) Trends Neurosci. , vol.17 , pp. 486-489
    • Rylett, R.J.1    Williams, L.R.2
  • 98
    • 0028447615 scopus 로고
    • Cellular mechanisms of signal transduction for neurotrophins
    • [98] Saitiel, A.R. and Decker, S.J., Cellular mechanisms of signal transduction for neurotrophins, BioEssays, 16 (1994) 405-411.
    • (1994) BioEssays , vol.16 , pp. 405-411
    • Saitiel, A.R.1    Decker, S.J.2
  • 99
    • 0027379653 scopus 로고
    • Hyperactivation of signal transduction systems in Alzheimer's disease
    • [99] Saitoh, T., Horsburgh, K. and Masliah, E., Hyperactivation of signal transduction systems in Alzheimer's disease, Ann. NY Acad. Sci., 640 (1991) 34-41.
    • (1991) Ann. NY Acad. Sci. , vol.640 , pp. 34-41
    • Saitoh, T.1    Horsburgh, K.2    Masliah, E.3
  • 100
    • 0029022112 scopus 로고
    • Nerve growth factor in Alzheimer's disease: Increased levels throughout the brain coupled with declines in nucleus basalis
    • [100] Scott, S.A., Mufson, E.J., Weingartner, J.A., Skau, K.A. and Crutcher, K.A., Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis, J. Neurosci., 15 (1995) 6213-6221.
    • (1995) J. Neurosci. , vol.15 , pp. 6213-6221
    • Scott, S.A.1    Mufson, E.J.2    Weingartner, J.A.3    Skau, K.A.4    Crutcher, K.A.5
  • 101
    • 0025991945 scopus 로고
    • Amyloid protein and Alzheimer's disease
    • [101] Selkoe, D.J., Amyloid protein and Alzheimer's disease, Sci. Am., November (1991) 40-47.
    • (1991) Sci. Am. , vol.NOVEMBER , pp. 40-47
    • Selkoe, D.J.1
  • 102
    • 0027367764 scopus 로고
    • Physiological production of the β-amyloid protein and mechanism of Alzheimer's disease
    • [102] Selkoe, D.J., Physiological production of the β-amyloid protein and mechanism of Alzheimer's disease, Trends Neurosci., 16 (1993) 403-408.
    • (1993) Trends Neurosci. , vol.16 , pp. 403-408
    • Selkoe, D.J.1
  • 105
    • 0028577208 scopus 로고
    • Immunohistochemical evidence for apoptosis in Alzheimer's disease
    • [105] Su, J.H., Anderson, A.J., Cummings, B.J. and Cotman, C.W., Immunohistochemical evidence for apoptosis in Alzheimer's disease, NeuroReport, 5 (1994) 2529-2533.
    • (1994) NeuroReport , vol.5 , pp. 2529-2533
    • Su, J.H.1    Anderson, A.J.2    Cummings, B.J.3    Cotman, C.W.4
  • 106
    • 0025877704 scopus 로고
    • The changing scene of neurotrophic factors
    • [106] Thoenen, H., The changing scene of neurotrophic factors, Trends Neurosci., 14 (1991) 165-170.
    • (1991) Trends Neurosci. , vol.14 , pp. 165-170
    • Thoenen, H.1
  • 107
    • 0025513602 scopus 로고
    • Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration
    • [107] Tuszynski, M.H., Sang, H., Amaral, D.G. and Gage, F.H., Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration, J. Neurosci., 10 (1990) 3604-3614.
    • (1990) J. Neurosci. , vol.10 , pp. 3604-3614
    • Tuszynski, M.H.1    Sang, H.2    Amaral, D.G.3    Gage, F.H.4
  • 108
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • [108] Ullrich, A. and Schlessinger, J., Signal transduction by receptors with tyrosine kinase activity, Cell, 61 (1990) 203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 110
    • 0024413110 scopus 로고
    • Neurotrophic factors and Alzheimer's disease
    • [110] Wainer, B.H., Neurotrophic factors and Alzheimer's disease, Neurobiol. Aging, 10 (1989) 540-542.
    • (1989) Neurobiol. Aging , vol.10 , pp. 540-542
    • Wainer, B.H.1
  • 111
    • 0023626621 scopus 로고
    • The expression, localisation and functional significance of β-nerve growth factor in the central nervous system
    • [111] Whittemore, S.R. and Seiger, A., The expression, localisation and functional significance of β-nerve growth factor in the central nervous system, Brain Res. Rev., 12 (1987) 439-464.
    • (1987) Brain Res. Rev. , vol.12 , pp. 439-464
    • Whittemore, S.R.1    Seiger, A.2
  • 112
    • 0026526206 scopus 로고
    • Stimulation of phosphatidylinositol hydrolysis by brain-derived neurotrophic factor and neurotrophin-3 in rat cerebral cortical neurons developing in culture
    • [112] Widmer, H.R., Knusel, B. and Hefti, F., Stimulation of phosphatidylinositol hydrolysis by brain-derived neurotrophic factor and neurotrophin-3 in rat cerebral cortical neurons developing in culture, J. Neurochem., 59 (1992) 2113-2124.
    • (1992) J. Neurochem. , vol.59 , pp. 2113-2124
    • Widmer, H.R.1    Knusel, B.2    Hefti, F.3
  • 113
    • 0026585924 scopus 로고
    • Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines
    • [113] Yoshida, K. and Gage, F.H., Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines, Brain Res., 569 (1992) 14-25.
    • (1992) Brain Res. , vol.569 , pp. 14-25
    • Yoshida, K.1    Gage, F.H.2
  • 114
    • 0029156292 scopus 로고
    • Multiple levels for regulation of trkA in PC12 cells by nerve growth factor
    • [114] Zhou, J., Valletta, J.S., Grimes, M.L. and Mobley, W.C., Multiple levels for regulation of trkA in PC12 cells by nerve growth factor, J. Neurochem., 65 (1995) 1146-1156.
    • (1995) J. Neurochem. , vol.65 , pp. 1146-1156
    • Zhou, J.1    Valletta, J.S.2    Grimes, M.L.3    Mobley, W.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.