Smoking impairs alveolar macrophage activation after inert dust exposure

Toxicology Letters

Volumn 88, Issue 1-3, 1996, Pages 131-137

  Moller W ^a   Barth, W ^b   Pohlit, W ^b   Rust, M ^c   Siekmeier, R ^c   Stahlhofen, W ^a   Heyder, J ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c Medizinische Klinik II   (Germany)

Author keywords

activation; human macrophages; magnetopneumography; phagosome motion

Indexed keywords

ADULT; CELL ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DUST; HUMAN; HUMAN EXPERIMENT; INHALATION; LUNG ALVEOLUS MACROPHAGE; MODEL; PHAGOSOME; PNEUMOGRAPHY; PRIORITY JOURNAL; SMOKING;

EID: 0030297199     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(96)03728-9     Document Type: Conference Paper

References (10)

1. [1] Cohen, D., Arai, S.F. and Brain, J.D. (1979) Smoking impairs long-term dust clearance from the lung. Science 294, 514-517.
2. [2] Stahlhofen, W. and Möller, W. (1993) Behaviour of magnetic micro-particles in the human lung. Radiat. Environ. Biophys. 32, 221-238.
3. [3] Stahlhofen, W. and Möller, W. (1994) In vivo and in vitro studies of the cellular defense system of the human lung. Toxicol. Lett. 72, 127-136.
4. [4] Möller, W., Stahlhofen, W. and Roth, C. (1990) Improved spinning top aerosol generator for the production of high concentrated ferrimagnetic aerosols. J. Aerosol Sci. 21 (Suppl. 1), S435-S438.
5. [5] Barth, W., Möller, W., Pohlit, W., Stahlhofen, W. and Wiegand, W. (1994) Magnetopneumographic estimation of particle phagocytosis in the human lungs. J. Aerosol Sci. 25 (Suppl. 1), S491-492.
6. [6] Nemoto, I. (1982) A model for magnetization and relaxation of ferrimagnetic particles in the lung. IEEE Trans. Biomed. Eng. BME-29, 745-752.
7. [7] Möller, W., Guzijan, V., Pohlit, W., Stahlhofen, W., Wenisch, T. and Wiegand, J. (1992) Cytomagnetometry with ferrimagnetic micro-particles - influence of particle size and dispersity. J. Aerosol Sci. 23 (Suppl. 1), S519-S522.
8. [8] Nemoto, I., Ogura, K. and Toyotama, H. (1989) Estimation of the energy of cytoplasmic movmements by magnetometry: effects of temperature and intracellular concentration of ATP. IEEE Trans. Biomed. Eng. BME-36 (6), 598-607.
9. [9] Gehr, P., Klauser, M. and Im Hof, V. (1989) Intracellular motility of pulmonary macrophages from smokers and nonsmokers. In: S.J. Williamson, M. Hoke, G. Stroink and M. Kotani (Eds.), Advances in Biomagnetism. Plenum Press, New York, London, pp. 473-476.
10. [10] Valberg, P.A., Jensen, W.A. and Rose, R.M. (1990) Cell organelle motions in bronchoalveolar lavage macrophages from smokers and nonsmokers. Am. Rev. Respir. Dis. 141, 1272-1279.