Exploitation of the complement system by Leishmania promastigotes

Parasitology Today

Volumn 12, Issue 11, 1996, Pages 444-447

  Brittingham, Andrew ^a   Mosser, David ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM; HOST PARASITE INTERACTION; LEISHMANIA; LEISHMANIASIS; NONHUMAN; PROMASTIGOTE; SHORT SURVEY;

MAMMALIA;

EID: 0030296985     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-4758(96)10067-3     Document Type: Article

References (32)

1. 1 Hall, B. and Joiner, K.A. (1991) Strategies of obligate intracellular parasites for evading host defences. Parasitol. Today 7, A22-A27
2. 2 Hindle, E. et al. (1926) Serological studies in Chinese Kala Azar. Pcoc. R. Soc. London B Biol. Sci. 100, 368-373
3. 3 Ulrich, M., Ortiz, D.T. and Con vit, J. (1968) The effect of fresh serum on leptomonads of leishmania. Trans. R. Soc. Trop. Med. Hyg. 62, 825-830
4. 4 Mosser, D.M. and Edelson, P.J. (1984) Activation of the alternative complement pathway by Leishmania promastigotes: parasite lysis and attachment to macrophages. J. Immunol. 132, 1501-1505
5. 5 Pearson, R.T. and Steigbigel, R.T. (1980) Mechanism of lethal effect of human serum upon Leishmania donovani. J. Immunol. 125, 2195-2201
6. 6 Puenres, S.M. et al. (1988) Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan. J. Exp. Med. 167, 887-902
7. 7 Green, P.J. et al. (1994) Recognition of the major cell surface glycoconjugates of Leishmania parasites by the human serum mannan-binding protein. Mol. Biochem. Parasitol. 66, 319-328
8. 8 Ikeda, K. et al. (1987) Serum lectin with known structure activates complement through the classical pathway. J. Biol. Chem. 262, 7451-7454
9. 9 Mosser, D.M., Springer, T.A. and Diamond, M.S. (1992) Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CDa11b/CD18). J. Cell Biol. 116, 511-520
10. 10 Russell, D.G. (1987) The macrophage-attachment glycoprotein gp63 is the predominant C3-acceptor site on Leishmania mexicana promastigotes. Eur. J. Biochem. 164, 213-221
11. 11 Brittingham, A. et al. (1995) Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis. J. Immunol. 155, 3102-3111
12. 12 Ross, G.D. and Medoff, M.E. (1985) Membrane complement receptors specific for bound fragments of C3. Adv. Immunol. 37, 217-267
13. 13 Franke, E.D. et al. (1985) Growth cycle dependent generation of complement-resistant Leishmania promastigotes. J. Immunol. 134, 2713-2718
14. 14 Puentes, S.M. et al. (1990) Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9. J. Immunol. 145, 4311-4316
15. 15 Davies, C.R. et al. (1990) Expression of LPG and GP63 by different developmental stages of Leishmania major in the sand-fly Phlebotomus papatasi. Parasitology 101, 337-343
16. 16 Saraiva, E.M.B. et al. (1995) Changes in lipophosphoglycan and gene expression associated with the development of Leishmania major in Phlebotomus papatasi. Parasitology 111, 275-287
17. 17 Grimm, F. and Jenni, L. (1993) Human serum resistant promastigotes of Leishmania infantum in the midgut of Phlebotomus perniciosus. Acta Trop. 52, 267-273
18. 18 Kweider, M. et al. (1989) Development of metacyclic Leishmania promastigotes is associated with the increasing expression of GP65, the major surface antigen. Parasite Immunol. 11, 197-209
19. 19 Ramamoorthy, R. et al. (1992) Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form. J. Biol. Chem. 267, 1888-1895
20. 20 Liu, X. and Chang, K.P. (1992) Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages. Proc. Natl. Acad. Sci. U. S. A. 89, 4991-4995
21. 21 Mosser, D.M. and Rosenthal, L.A. (1993) Leishmania-macrophage interactions: multiple receptors, multiple ligands, and diverse cellular responses. Semin. Cell Biol. 4, 315-322
22. 22 Jeronimo, S.M.B. and Pearson, R.D. (1992) in The Leishmania: Protozoans Adapted for Extracellular and Intracellular Survival; Subcellular Biochemistry, Vol. 18: Intracellular Parasites (Avila, J.L. and Harris, J.R., eds), pp 1-37, Plenum Press
23. 23 Mosser, D.M. and Edelson, P.J. (1985) The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes. J. Immunol. 135, 2785-2789
24. 24 Blackwell, J.M. et al. (1985) Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum. J. Exp. Med. 162, 324-331
25. 25 Wozencraft, A.O. and Blackwell, J.M. (1987) Increased infectivity of stationary-phase promastigotes of Leishmania donovani: correlation with enhanced C3 binding capacity and CR3-mediated attachment to host macrophages. Immunology 60, 559-563
26. 26 DaSilva, R.P. et al. (1989) CR1, the C3b receptor, mediates binding of infective Leishmania major promastigotes to human macrophages. J. Immunol. 143, 617-622
27. 27 Sutterwala, F.S., Rosenthal, L.A. and Mosser, D.M. (1996) Cooperation between CR1 (CD35) and CR3 (CD11b/CD18) in the binding of complement-opsonized particles. J. Leukocyte Biol. 59, 883-890
28. 28 Rosenthal, L.A. et al. (1996) Leishmania major-human macrophage interactions: cooperation between Mac-1 (CD11b/CD18) and complement receptor type 1 (CD35) in promastigote adhesion. Infect. Immun. 64, 2206-2215
29. 29 Mosses D.M. and Edelson, P.J. (1987) The third component of complement (C3) is responsible for the intracellular survival of Leishmania major. Nature 327, 329-331
30. 30 Sacks, D.L. (1992) The structure and function of the surface lipophosphoglycan on different developmental stages of Leishmania promastigotes. Infect. Agents Dis. 1, 200-206
31. 31 Yancey, K.B. et al. (1985) Human C5a modulates monocyte Fc and C3 receptor expression. J. Immunol. 135, 465-470
32. 32 Bray, R.S. (1983) Leishmania: chemotaxic response of promastigotes and macrophages in vitro. J. Protozool. 30, 322-329