Permeability of the blood-brain barrier to protein and [3H]GABA in intraparenchymal fetal CNS tissue grafts

Experimental Neurology

Volumn 142, Issue 1, 1996, Pages 66-79

  Rosenstein, Jeffrey M ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID H 3; HORSERADISH PEROXIDASE; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EMBRYO; NEOCORTEX; NERVE GRAFT; NONHUMAN; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

EID: 0030296973     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1996.0179     Document Type: Article

References (39)

1. 1. BEGGS, J. L., AND J. D. WAGGENER. 1976. Transendothelial vesicular transport of protein following compression injury to the spinal. Lab. Invest. 34: 428-139.
2. 2. BERTRAM, K., AND M. SHIPLEY et al. 1994. Permeability of the blood-brain barrier within rat intrastriatal transplants assessed by simultaneous systemic injection of horseradish peroxidase and evans blue dye. Exp. Neurol. 127: 245-252.
3. 3. BROADWELL, R. D., H. M. CHARLTON, B. J. BALIN, AND M. SALCMAN. 1987. Angioarchitecture of the CNS, pituitary gland and intracerebral grafts revealed with peroxidase cytochemistry. J. Comp. Neurol. 260: 47-62.
4. 4. BROADWELL, R. O., H. M. CHARLTON, W. F. GANONG, M. SALCMAN, AND M. SOFRONIEW. 1989. Allografts of CNS tissue possess a blood-brain barrier. I. Grafts of medial preoptic area in hypogonadal mice. Exp. Neurol. 105: 135-151.
5. 5. BROADWELL, R., H. CHARLTON et al. 1991. Allografts of CNS tissue possess a blood-brain barrier. II. Angiogenesis in solid and cell suspension grafts. Exp. Neurol. 112: 1-28.
6. 6. BROADWELL, R., B. BAKER, P. EBERT AND W. HICKEY. 1994. Allografts of CNS tissue possess a blood-brain barrier. III. Neuropathological, methodological and immunological considerations. Microsc. Res. Technol. 27: 471-494.
7. 7. BROADWELL, R., B. BAKER, AND W. HICKEY. 1995. CNS transplants and the host immune response: The blood-brain barrier and immunological privilege within the mammalian brain. In New Concepts of a Blood-Brain Barrier (J. Greenwood, et al., Eds.), pp. 299-309. Plenum, New York.
8. 8. BRUNDIN, P., H. WIDNER, O. NILSSON, R. STRECKER, AND A. BJÖRKLUND. 1989. Intracerebral xenografts of dopamine neurons: The role of immunosuppression and the blood-brain barrier. Exp. Brain Res. 75: 195-207.
9. 9. CHRONWALL, B., AND J. WOLFE. 1980. Prenatal and postnatal development of GABA-accumulating cells in the occipital neocortex of rat. J. Comp. Neurol. 190: 187-208.
10. 10. DUSART, I., F. NOTHIAS, F. ROUDIER, J. BESSON, AND M. PESCHANSKI. 1989. Vascularization of fetal cell suspension grafts in the excitotoxically lesioned adult rat thalamus. Dev. Brain Res. 48: 215-228.
11. 11. GEIST, M., D. MARIS, AND M. GRADY. 1991. Blood-brain barrier permeability is not altered by allograft or xenograft fetal neural cell suspension grafts. Exp. Neurol. 111: 166-174.
12. 3H-GABA). Exp. Brain Res. 14: 354-362.
13. 13. HORNER, P., P. REIER, AND B. STOKES. 1996. Quantitative analysis of vascularization and cytochrome oxidase following fetal transplantation in the contused rat spinal cord. J. Comp. Neurol. 364: 690-703.
14. 14. KLAUSEN, B., R. SWENSON, J. ZIMMER AND A. CASTRO. 1992. Fetal neocortical transplants in rats: Blood-brain barrier development and partial permeability to IgG in long-surviving grafts. Restor. Neurol. Neurosci. 4: 393-400.
15. 15. KRUM, J. M., AND J. M. ROSENSTEIN. 1988. Patterns of angiogenesis in neural transplant models. II. Fetal neocortical transplants. J. Comp. Neurol. 271: 331-345.
16. 16. KRUM, J. M., AND J. M. ROSENSTEIN. 1989. The fine structure of vascular-astroglial relations in transplanted fetal neocortex. Exp. Neurol. 103: 203-212.
17. 17. LEIGH, K., K. ELISEVICH AND K. ROGERS. 1994. Vascularization and microvascular permeability in solid versus cell-suspension embryonic neural grafts. J. Neurosurg. 81: 272-283.
18. 18. MASON, D., H. CHARLTON, A. JONES, C. LAVY, M. PUKLAVEC AND S. SIMMONDS. 1986. The fate of allogeneic and xenogeneic tissue transplanted into the third ventricle of rodents. Neuroscience 19: 685-694.
19. 19. NAKASHIMA, H., K. KAWAMURA, AND I. DATE. 1988. Immunological reaction and blood-brain barrier in mouse-to-rat cross-species neural graft. Brain Res. 475: 237-243.
20. 20. NARADZAY, J., AND J. M. ROSENSTEIN. 1989. Vascular morphology and permeability in fetal neocortical tissue grafts to the kidney capsule. Exp. Neurol. 104: 284-291.
21. 21. NORDBERG, C., T. SOKRAB AND B. B. JOHANSSON. 1991. The relationship between plasma protein extravasation and remote tissue changes after experimental brain infarction. ACTA Neuropathol. 82: 118-126.
22. 22. OLDENDORF, W. H. 1971. Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. Am. J. Physiol. 221: 1629-1639.
23. 23. OLDENDORF, W. H. 1977. The blood-brain barrier. Exp. Eye Res. Suppl. 25: 177-190.
24. 24. REIER, P. AND J. HOULE. 1988. The glial scar: Its bearing on axonal elongation and transplantation approaches to CNS repair. In Functional Recovery and Neurological Disease, Advances in Neurology (S. Waxman, Ed.), pp. 87-138. Raven, New York.
25. 25. RISLING, M., H. LINDÅ, S. CULLHEIM, AND P. FRANSON. 1989. A persistent defect in the blood-brain barrier after ventral funiculus lesion in adult cats: Implications for CNS regeneration? Brain Res. 494: 13-21.
26. 26. ROSENSTEIN, J. M. 1987. Neocortical transplants in the mammalian brain lack a blood-brain barrier to macromolecules. Science 235: 772-774.
27. 3HGABA in CNS tissue grafts. I. Intraventricular grafts. J. Comp. Neurol. 305: 676-690.
28. 28. ROSENSTEIN, J. M. 1993. Developmental expression of neuron-specific enolase (NSE) immunoreactivity and cytochrome oxidase activity in neocortical transplants. Exp. Neurol. 124: 208-218.
29. 29. ROSENSTEIN, J. M. 1995. Why do neural transplants survive? An examination of some metabolic and pathophysiological considerations in neural transplantation. Exp. Neurol. 133: 1-6.
30. 30. ROSENSTEIN, J. M. AND J. M. KRUM. 1996. Cytoskeletal protein immunoxpression in fetal neural grafts: Distribution of phosphorylated and non-phosphorylated neurofilament protein and microtubule-associated protein (MAP-2). Cell Trans. 5: 233-241.
31. 31. ROSENSTEIN, J. M. AND N. S. MORE. 1994. Immunocytochemical expression of the blood brain barrier glucose transporter (GLUT 1) in neural transplants and brain wounds. J. Comp. Neurol. 350: 229-240.
32. 32. ROSENSTEIN, J., N. MORE AND J. KRUM. 1994. Immunocytochemical distribution of the brain glucose transporter GLUT 1 in experimental gliosis. Brain Res. 659: 277-282.
33. 33. SAMPAOLO, S., Y. NAKAGAWA, F. IANNOTTI, J. CERVOS-NAVARRO, AND V. BONARITA. 1991. Blood-brain barrier permeability to micromolecules and edema formation in the early phase of incomplete continuous ischemia. ACTA Neuropathol. 82: 107-111.
34. 34. SANBERG, P., D. NASH, S. CALDERON, M. GIORDANO AND M. S. LIPLEY. 1988. Neural transplants disrupt the blood-brain barrier and allow peripherally acting drugs to exert a centrally mediated behavioral effect. Exp. Neurol. 102: 149-152.
35. 35. SCHMIDT-KASTNER, R., J. SZYMAS, AND K. HOSSMAN. 1990. Immunohistochemical study of glial reaction and serum-protein extravasation in relation to neuronal damage in rat hippocampus after ischemia. Neuroscience 38: 527-540.
36. 36. SMITH, L. AND F. EBNER. 1986. The differentiation of non-neural elements in neocortical transplants. In Neural Transplantation and Regeneration (G. Das, Ed.), pp. 81-101. Springer, New York.
37. 37. SWENSON, R., P. SHAW, V. ALONES, G. KOZLOWSKI, AND J. ZIMMER. 1989. Neocortical transplants grafted into the newborn rat brain demonstrate a blood-brain barrier to macromolecules. Neurosci. Lett. 100: 35-39.
38. 38. WIEGAND, S. J., AND D. M. GASH. 1988. Characteristics of vasculature and neovascular relations in intraventricular anterior hypothalamic transplants. Brain Res. Bull. 20: 105-124.
39. 39. YOUNG, M. J., K. RAO, AND R. D. LUND. 1989. Integrity of the blood-brain barrier in retinal xenografts is correlated with the immunological status of the host. J. Comp. Neurol. 283: 107-117.