A continuous fluorimetric method to monitor the enzymatic hydrolysis of medicinal esters

Journal of Pharmaceutical and Biomedical Analysis

Volumn 15, Issue 2, 1996, Pages 149-155

  Salvi, Aline ^a   Mayer, Joachim M ^a   Carrupt, Pierre Alain ^a   Testa, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

BCECF; esters; hog liver carboxylesterase; human serum albumin; hydrolysis; pH indicator; prodrugs; spectrofluorimetric assay

Indexed keywords

NICOBOXIL; NICOTINIC ACID 2 METHOXYETHYL ESTER; NICOTINIC ACID ESTER; NICOTINIC ACID ETHYL ESTER; NICOTINIC ACID PROPYL ESTER; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CALIBRATION; DRUG DETERMINATION; DRUG MONITORING; HYDROLYSIS; IN VITRO STUDY; PRIORITY JOURNAL; SPECTROFLUOROMETRY; TECHNIQUE;

EID: 0030296497     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/0731-7085(96)01837-7     Document Type: Article

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