Eprinomectin: A novel avermectin for use as a topical endectocide for cattle

International Journal for Parasitology

Volumn 26, Issue 11, 1996, Pages 1237-1242

  Shoop, W L ^a   Egerton, J R ^a   Eary, C H ^a   Haines, H W ^a   Michael, B F ^a   Mrozik, H ^a   Eskola, P ^a   Fisher, M H ^a   Slayton, L ^a   Ostlind, D A ^a   Skelly, B J ^a   Fulton, R K ^a   Barth, D ^a   Costa, S ^a   Gregory, L M ^a   Campbell, W C ^a   Seward, R L ^a   Turner, M J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

avermectins; efficacy; endectocide; eprinomectin

Indexed keywords

AVERMECTIN; EPRINOMECTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATTLE; CONTROLLED STUDY; DRUG EFFICACY; HELMINTHIASIS; INFESTATION; NONHUMAN; PARASITOSIS; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTHELMINTICS; CATTLE; CATTLE DISEASES; DIPTERA; DRUG DESIGN; FEMALE; HELMINTHS; IVERMECTIN; LACTATION; MITE INFESTATIONS; MITES; NEMATODE INFECTIONS; SHEEP; SHEEP DISEASES; STRUCTURE-ACTIVITY RELATIONSHIP;

ACARI; ANIMALIA; ANOPLURA; BOS TAURUS; CHORIOPTES; CHORIOPTES BOVIS; COOPERIA ONCOPHORA; COOPERIA PUNCTATA; DICTYOCAULUS VIVIPARUS; HAEMATOBIA IRRITANS; HAEMONCHUS PLACEI; LINOGNATHUS VITULI; NEMATODIRUS HELVETIANUS; OESOPHAGOSTOMUM RADIATUM; ONCOPHORA; OSTERTAGIA OSTERTAGI; PHTHIRAPTERA; TRICHOSTRONGYLUS AXEI; TRICHOSTRONGYLUS COLUBRIFORMIS; VIVIPARUS;

EID: 0030295003     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(96)00123-3     Document Type: Article

References (4)

1. 1a component. Antimicrobial Agents and Chemotherapy 15: 372-378.
2. 1, a new broad-spectrum antiparasitic agent. British Veterinary Journal 136: 88-97.
3. Mrozik H., Eskola P., Arison B. H., Linn B. O., Lusi A., Matzuk A., Shih T. L., Tischler M., Waksmunski F. S., Wyvratt M. J., Blizzard T. A., Margiatto G. M., Fisher M. H., Shoop W. L. & Egerton J. R. 1995. 4″-Deoxy-4″-aminoavermectins with potent broad spectrum antiparasitic activities. Bioorganic and Medicinal Chemistry Letters 5: 2435-2440.
4. Shoop W. L., DeMontigny P., Fink D. W., Williams J. B., Egerton J. R., Mrozik H., Fisher M. H., Skelly B. J. & Turner M. J. 1996. Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle. International Journal for Parasitology 26: 1227-1235.