Biochemical characterization of atroxase and nucleotide sequence encoding the fibrinolytic enzyme

Toxicon

Volumn 34, Issue 11-12, 1996, Pages 1295-1300

  Tu, Anthony T ^a   Baker, Brenda ^a   Wongvibulsin, Sirima ^a   Willis, Todd ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; SNAKE VENOM;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD CLOTTING; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME STRUCTURE; FIBRINOLYSIS; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; THROMBUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CROTALID VENOMS; FIBRINOLYTIC AGENTS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA;

EID: 0030294853     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(96)00106-7     Document Type: Conference Paper

References (7)

1. Baker, B. J., Wongvibulsin, S., Nyborg, J. and Tu, A. T. (1995) Nucleotide sequence encoding the snake venom fibrinolytic enzyme atroxase obtained from a Crotalus atrox venom gland cDNA library. Arch. Biochem. Biophys. 317, 357-364.
2. Datta, G., Dong, A., Witt, J. and Tu, A. T. (1995) Biochemical characterization of Basilase, a fibrinolytic enzyme from Crotalus basiliscus basiliscus. Arch. Biochem. Biophys. 317, 365-373.
3. Loayza, S. L., Trikha, M., Markland, F. S., Riquelme, P. and Kuo, J. (1994) Resolution of isoforms of natural and recombinant fibrolase, the fibrinolytic enzyme from Agkistrodon contortrix contortrix snake venom, and comparison of their EDTA sensitivities. J. Chromat. B 662, 227-243.
4. Rael, E. D., Martinez, M. and Molina, O. (1992) Isolation of a fibrinolytic protease, M4, from venom of Crotalus molossus molossus (northern blacktail rattlesnake). Haemostasis 22, 41-49.
5. Siigur, E. and Siigur, J. (1991) Purification and characterization of lebetase, a fibrinolytic enzyme from Vipera lebetina (snake) venom. Biochim. biophys. Acta 1074, 223-229.
6. Willis, T. W. and Tu, A. T. (1988) Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom. Biochemistry 27, 4769-4777.
7. Willis, T. W., Tu, A. T. and Miller, C. W. (1989) Thrombolysis with a snake venom protease in a rat model of venous thrombosis. Thromb. Res. 53, 19-29.