A simple biochemical method in the search for bioactive polypeptides in a sea anemone (Anemonia sulcata)

Toxicon

Volumn 34, Issue 11-12, 1996, Pages 1361-1366

  Sanchez, J ^a   Bruhn, T ^a   Aneiros, A ^b   Wachter, E ^c   Beress L ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b Centro de Bioactivos Marinos   (Cuba)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE INHIBITOR; POLYPEPTIDE; PROTEINASE INHIBITOR; SEA ANEMONE TOXIN;

CHROMATOGRAPHY; CONFERENCE PAPER; DRUG ISOLATION; DRUG SCREENING; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; TOXIN ANALYSIS;

ANIMALS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; CNIDARIAN VENOMS; PEPTIDES; SEA ANEMONES;

EID: 0030294816     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(96)00097-9     Document Type: Conference Paper

References (15)

1. Aneiros, A., Garateix, A., Alvarez, J., Ortiz, P., Sánchez, J., Karlsson, E. and Béress, L. (1995) Isolation of new bioactive substances from sea anemones of cuban in-shore waters. In: Fifth International Symposium on Neurotoxins in Neurobiology, 31 August to 5 September, University of Puerto Rico, Abstract 2-10. Mayagüez: University of Puerto Rico.
2. Béress, L. and Béress, R. (1971) Reinigung zweier krabbenlähmender Toxine aus der Seeanemone Anemonia sulcata. Kiel. Meeresforsch. 27, 117-127.
3. Béress, L., Béress, R. and Wunderer, G. (1975) Purification of three polypeptides with neuro- and cardio-toxic activity from the sea anemone Anemonia sulcata. Toxicon 13, 359-367.
4. Béress, L., Doppelfeld, I.-S., Etschenberg, E., Graf, E., Henschen, A. and Zwick, J. (1985) Polypeptide, Verfahren zu ihrer Herstellung und ihre Verwendung als blutdrucksenkende Wirkstoffe. Federal Republic of Germany Patent DE 3324689 A1.
5. Béress, L., Wachter, E., Béress, R., Zurick, J., Leimenstoll, A., Fritz, H. and Wassermann, O. (1993) Isolation and characterization of biologically active polypeptides from the sea anemone Anemonia sulcata: 25 years' work on marine toxins. Toxicon 31, 498.
6. Driscoll, P. C., Clore, G. M., Béress, L. and Gronenborn, A. M. (1989a) A proton nuclear magnetic resonance study of the antihypertensive and antiviral protein BdS I from the sea anemone Anemonia sulcata: sequential and stereospecific resonance assignment and secondary structure. Biochemistry 28, 2178-2187.
7. Driscoll, P. C., Gronenborn, A. M., Béress, L. and Clore, G. M. (1989b) Determination of the three-dimensional solution structure of the antihypertensive and antiviral protein BdS I from the sea anemone Anemonia sulcata: a study using nuclear resonance and hybrid distance geometry-dynamical simulation annealing. Biochemistry 28, 2188-2198.
8. Fritz, H., Brey, B. and Béress, L. (1972) Polyvalente Isoinhibitoren für Trypsin, Chymotrypsin, Plasmin und Kallikrein aus Seeanemonen (Anemonia sulcata), Isolierung Hemmverhalten und Aminosäurezusammensetzung. Hoppe-Seyler's Z. physiol. Chem. 353, 19-30.
9. Kolkenbrock, H. and Tschesche, H. (1987) A new inhibitor of elastase from the sea anemone Anemonia sulcata. Hoppe-Seyler's Z. physiol. Chem. 368, 93-99.
10. Müller, W. (1990) New ion exchangers for the chromatography of biopolymers. J. Chromat. 510, 133-140.
11. Norton, R. S. (1991) Structure and structure function relationship of sea anemone proteins that interact with the sodium channel. Toxicon 29, 1051-1084.
12. Sánchez, J., Bruhn, T., Aneiros, A. and Béress, L. (1995) A simple method for the isolation of toxins from Anemonia sulcata. Eight Congress on Marine Natural Products, Santa Cruz de Tenerife, Spain, 10-15 September, p. 128.
13. Schweitz, H., Vincent, J. P., Barhanin, J., Frelin, C., Linden, G., Hugues, G. and Lazdunski, M. (1981) Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus and Actinodendron plumosum. Biochemistry 20, 5245-5252.
14. + channels. J. biol. Chem. 270, 25121-25126.
15. Wachter, E., Klostermann, G., Binder, A. and Béress, L. (1987) Isolation of isotoxins from the sea anemone Anemonia sulcata by HPLC-chromatography. In: Receptors and Ion Channels, pp. 313-322 (Ovchinnikov, Y. A. and Hucho, F., Eds). Berlin; Walter de Gruyter.