Characterization of the major metalloprotease isolated from the venom of the northern Pacific rattlesnake, Crotalus viridis oreganus

Toxicon

Volumn 34, Issue 11-12, 1996, Pages 1277-1285

  Mackessy, Stephen P ^a  

^a UNIVERSITY OF NORTHERN COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE; CASEIN; EDETIC ACID; EGTAZIC ACID; METALLOPROTEINASE; PROTEINASE; SERINE PROTEINASE INHIBITOR; SNAKE VENOM;

AMINO ACID SEQUENCE; CONFERENCE PAPER; DEGRADATION; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME STABILITY; ENZYME STRUCTURE; HEMOSTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; CHROMATOGRAPHY, ION EXCHANGE; CROTALID VENOMS; METALLOENDOPEPTIDASES;

EID: 0030294697     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(96)00100-6     Document Type: Conference Paper

References (20)

1. Bjarnason, J. B. and Fox, J. W. (1983) Proteolytic specificity and cobalt exchange of hemorrhagic toxin e, a zinc protease isolated from the venom of the western diamondback rattlesnake (Crotalus atrox). Biochemistry 22, 3770-3778.
2. Bjarnason, J. B. and Fox, J. W. (1989) Hemorrhagic toxins from snake venoms. J. Toxic. Toxin Rev. 7, 121-209.
3. Bjarnason, J. B. and Fox, J. W. (1995) Snake venom metalloendopeptidases: reprolysins. In: Methods in Enzymology: Proteolytic Enzymes: Aspartic and Metallo Peptidases, Vol. 248, pp. 345-368 (Barrett, A. J., Ed.). New York: Academic Press.
4. Bjarnason, J. B. and Tu, A. T. (1978) Hemorrhagic toxins from western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e. Biochemistry 17, 3395-3404.
5. 2. Toxicon 33, 763-770.
6. Fox, J. W. and Bjarnason, J. B. (1995) Atrolysins: metalloproteinases from Crotalus atrox venom. In: Methods in Enzymology: Proteolytic Enzymes: Aspartic and Metallo Peptidases, Vol. 248, pp. 345-368 (Barrett, A. J., Ed.). New York: Academic Press.
7. Francis, B., Seebart, C. and Kaiser, I. I. (1992) Citrate is an endogenous inhibitor of snake venom enzymes by metal-ion chelation. Toxicon 30, 1239-1246.
8. Hite, L. A., Shannon, J. D., Bjarnason, J. B. and Fox, J. W. (1992) Sequence of a cDNA clone encoding the zinc metalloproteinase hemorrhagic toxin e from Crotalus atrox: evidence for signal, zymogen and disintegrin-like structures. Biochemistry 31, 6203-6211.
9. Jiang, W. and Bond, J. S. (1992) Families of metalloendopeptidases and their relationships. FEBS Lett. 312, 110-114.
10. Kini, R. M. and Evans, H. J. (1992) Structural domains in venom proteins: evidence that metalloproteinases and nonenzymatic platelet aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor. Toxicon 30, 265-293.
11. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277, 680-685.
12. Mackessy, S. P. (1988) Venom ontogeny in the Pacific rattlesnakes Crotalus viridis helleri and C. v. oreganus. Copeia 1988, 92-101.
13. Mackessy, S. P. (1993) Fibrinogenolytic proteases from the venoms of juvenile and adult northern Pacific rattlesnakes (Crotalus viridis oreganus). Comp. Biochem. Physiol. 106B, 181-189.
14. Neurath, H. (1989) The diversity of proteolytic enzymes. In: Proteolytic Enzymes: A Practical Approach, p. 1 (Beynon, R. J. and Bond, J. S., Eds). Oxford: IRL Press.
15. Ouyang, C. and Huang, T.-F. (1979) α- and β-fibrinogenases from Trimeresurus gramineus snake venom. Biochim. biophys. Acta 571, 270-283.
16. Russell, F.E. (1980) Snake Venom Poisoning. Philadelphia: J.B. Lippincott Co.
17. Shannon, J. D., Baramova, E. N., Bjarnason, J. B. and Fox, J. W. (1989) Amino acid sequence of a Crotalus atrox venom metalloproteinase which cleaves type IV collagen and gelatin. J. biol. Chem. 264, 11575-11583.
18. Takeya, H., Oda, K., Miyata, T., Omori-Satoh, T. and Iwanaga, S. (1990) The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flaxvoviridis. J. biol. Chem. 265, 16068-16073.
19. Utaisincharoen, P., Mackessy, S. P., Miller. R. A. and Tu, A. T. (1993) Complete primary structure and biochemical properties of gilatoxin, a serine protease with kallikrein-like and angiotensin-degrading activities. J. biol. Chem. 268, 21975-21983.
20. Vassalli, J.-D. and Pepper, M. S. (1994) Membrane proteases in focus. Nature 370, 14-15.