Anti-muscarinic toxins from Dendroaspis augusticeps

Toxicon

Volumn 34, Issue 11-12, 1996, Pages 1257-1267

  Liang, J S ^a   Carsi Gabrenas, J ^a   Krajewski, J L ^a   McCafferty, J M ^a   Purkerson, S L ^a   Santiago, M P ^a   Strauss, W L ^a   Valentine, H H ^a   Potter, L T ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCARINIC RECEPTOR; RECEPTOR SUBTYPE; SNAKE VENOM;

AMINO ACID SEQUENCE; ANIMAL TISSUE; BINDING SITE; CONFERENCE PAPER; HIPPOCAMPUS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; TOXIN ANALYSIS; TOXIN STRUCTURE;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; CRICETINAE; ELAPID VENOMS; ELAPIDAE; MOLECULAR SEQUENCE DATA; MUSCARINIC ANTAGONISTS; NEUROTOXINS; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, MUSCARINIC M1; RECEPTORS, MUSCARINIC;

EID: 0030294542     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(96)00109-2     Document Type: Conference Paper

References (21)

1. Adern, A., Asblom, A., Johansson, G., Mbugua, P. M. and Karlsson, E. (1988) Toxins from the venom of the green mamba Dendroaspis angusticeps that inhibit the binding of quinuclidinyl benzilate to muscarinic acetylcholine receptors. Biochim. biophys. Acta 968, 340-345.
2. Adem, A., Bogdanovic, N., Islam, A., Jolkkonen, M., Winblad, B. and Karlsson, E. (1995) Distribution of M4 muscarinic cholinergic receptors in the rat brain detected by a selective mamba toxin (MT-3). Life Sci. 56, 1013.
3. Harvey, A. L., Anderson, A. J., Mbugua, P. M. and Karlsson, E. (1984) Toxins from mamba venoms that facilitate neuromuscular transmission. J. Toxic.-Toxin Rev. 3, 91-137.
4. Hulme, E. C., Birdsall, N. J. M. and Buckley, N. J. (1990) Muscarinic receptor subtypes. A. Rev. Pharmac. 30, 633-673.
5. Jerusalinsky, D., Cervenansky, C., Walz, R., Bianchin, M. and Izquierdo. I. (1993) A peptide muscarinic toxin from the green mamba venom shows agonist-like action in an inhibitory avoidance learning task. Eur. J. Pharmac. 240, 103-105.
6. Jolkkonen, M., van Giersbergen, P. L. M., Hellman, U., Wernstedt, C. and Karlsson, E. (1994) A toxin from the green mamba Dendroaspis angusticeps: amino acid sequence and selectivity for muscarinic m4 receptors. Fedn Eur. biochem. Socs Lett. 352, 91-94.
7. Karlsson, E., Risinger, C., Jolkkonen, M., Wernstedt, C. and Adem, A. (1991) Amino acid sequence of a snake toxin that binds to the muscarinic receptor. Toxicon 29, 521-526.
8. Karlsson., E., Jolkkonen, M., Satyapan, N., Adem, A., Kumlin, E., Hellman, U. and Wernstedt, C. (1994) Protein toxins that bind to muscarinic acetylcholine receptors. Ann. N.Y. Acad. Sci. 710, 153-161.
9. Kornisuik, E., Jerusalinsky, D., Cervenansky, C. and Harvey, A. L. (1995a) Binding of muscarinic toxins MT × 1 and MT × 2 from the venom of the green mamba Dendroaspis angusticeps to cloned human muscarinic cholinoceptors. Toxicon 33, 11-18.
10. Kornisuik, E., Jerusalinsky, D., Cervanansky, C. and Harvey, A. L. (1995b) Binding of muscarinic toxins MT × 1 and MT × 2 from the venom of the green mamba Dendroaspis angusticeps to cloned human muscarinic cholinoceptors (Corrigendum). Toxicon 33, 1111.
11. Low, B. E., Preston, H. S., Sato, A., Rosen, L. S., Searl, J. E., Rudko, A. D. and Richardson, J. S. (1976) Three dimensional structure of erabutoxin b neurotoxic protein: inhibitor of acetylcholine receptor. Proc. natn. Acad. Sci. U.S.A. 73, 2991-2994.
12. Max, S. E. Liang, J.-S. and Potter, E. T. (1993a) Purification and properties of m1-toxin, a specific antagonist of m1 muscarinic receptors. J. Neurosci. 13, 4293-4300.
13. Max, S. E. Liang, J.-S., Valentine, H. H. and Potter, E. T. (1993b) Use of m1-toxin as a selective antagonist of m1 muscarinic receptors. J. Pharmac. exp. Ther. 267, 480-485.
14. Max, S. E. Liang, J.-S. and Potter. L. T. (1993c) Stable allosteric binding of m1-toxin to m1 muscarinic receptors. Molec. Pharmac. 44, 1171-1175.
15. Max, S. I., Liang, J. S., Purkerson, S. L. and Potter, L. T. (1993d) m4-Toxin, a selective, reversible, allosteric antagonist of m4 muscarinic receptors. Neurosci. Abstr. 19, 462.
16. Pillet, L., Tremeau, O., Ducancel, F., Drevet, P., Zinn-Justin, S., Pinkasfeld, S., Boulain, J.-C. and Ménez, A. (1993) Genetic engineering of snake toxins. J. biol. Chem. 268, 909-916.
17. Potter, L. T. and Purkerson, S. L. (1995) Pharmacology of striatal muscarinic receptors. In: Molecular and Cellular Mechanisms of Neostriatal Function, pp. 241-254 (Ariano, M. A. and Surmeier, D. J., Eds). Georgetown, TX: R.G. Landes Co.
18. Potter, L. T., Hanchett-Valentine, H., Liang, J.-S., Max, S. L. Purkerson, S. L., Silberberg, H. A. and Strauss, W. L. (1993) m1-Toxin. Life Sci. 52, 433-440.
19. Ségalas, L. Roumestand, C., Zinn-Justin, S., Gilquin, B., Ménez, R. and Toma, F. (1995) Solution structure of a green mamba toxin that activates muscarinic acetylcholine receptors, as studied by nuclear magnetic resonance and molecular modeling. Biochemistry 34, 1248-1260.
20. Surmeier, D. J., Cantrell, A. R. and Carter-Russell, H. (1995) Dopaminergic and cholinergic modulation of calcium conductances in neostriatal neurons. In: Molecular and Cellular Mechanisms of Neostriatal Function, pp. 193-215 (Ariano, M. A. and Surmeier, D. J., Eds). Georgetown, TX: R.G. Landes Co.
21. Tsernoglou, D. and Petsko, G. A. (1976) The crystal structure of a postsynaptic neurotoxin from sea snake at 2.2 Å resolution. Fedn Eur. biochem. Socs Lett. 68, 1-4.