Cyclic operation of ceramic-matrix animal cell bioreactors for controlled secretion of an endocrine hormone. A comparison of single-pass and recycle modes of operation

Biotechnology Progress

Volumn 12, Issue 6, 1996, Pages 837-846

  Grampp, Gustavo E ^a,b   Applegate, Mark A ^a,c   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b AMGEN INC   (United States)

^c Advanced Tissue Sciences Liquidating Trust   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL VARIABLES CONTROL; INSULIN; MASS TRANSFER; PROCESS CONTROL; THERMAL CYCLING;

CERAMIC MATRIX ANIMAL CELL BIOREACTORS; CONTROLLED SECRETION PROCESS; ENDOCRINE HORMONE; HIGH DENSITY BIOREACTORS; MURINE INSULIN; PERFUSION SYSTEM; RECYCLE REACTOR; SINGLE PASS REACTOR;

BIOREACTORS;

GLUCOSE; INSULIN; LACTIC ACID;

ANIMAL; ARTICLE; BIOREACTOR; CELL LINE; COMPARATIVE STUDY; CULTURE MEDIUM; KINETICS; METABOLISM; MOUSE; SECRETION;

ANIMALS; BIOREACTORS; CELL LINE; CULTURE MEDIA; GLUCOSE; INSULIN; KINETICS; LACTIC ACID; MICE;

EID: 0030294324     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp960066r     Document Type: Article

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