BMEC-1: A human bone marrow microvascular endothelial cell line with primary cell characteristics

Microvascular Research

Volumn 52, Issue 3, 1996, Pages 221-234

  Candal, Francisco J ^a   Rafii, Shahin ^b   Parker, Jeffery T ^a   Ades, Edwin W ^a   Ferris, Barbara ^b   Nachman, Ralph L ^b   Kellar, Kathryn L ^a  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^b WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; CYTOKINE; GROWTH FACTOR; MEMBRANE ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW; CELL STRUCTURE; ENDOTHELIUM CELL; HEMATOPOIESIS; HUMAN; PHENOTYPE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ULEX;

EID: 0030294235     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1006/mvre.1996.0060     Document Type: Article

References (23)

1. Ades, E. W., Candal, F. J., Swerlick, R. A., George, V. G., Summers, S., Bosse, D. C., and Lawley, T. J. (1992). HMEC-1: Establishment of an immortalized human microvascular endothelial cell line. J. Invest. Dermatol 99, 683-609.
2. 40 large T antigen under the influence of an inducible (metallothionein) promoter. Blood 80, 102-112.
3. Collins, L. S., and Dorshkind, K. (1987). A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis. J. Immunol. 138, 1082-1087.
4. Davis, T. A., Robinson, D. H., Lee, K. P., and Kessler, S. W. (1995). Porcine brain microvascular endothelial cells support the in vitro expansion of human primitive hematopoietic bone marrow progenitor cells with a high replating potential: Requirement of cell-to-cell interactions and colony-stimulating factors. Blood 85, 1751-1761.
5. Davison, P. M., Bensch, K., and Karasek, U. (1980). Isolation and growth of endothelial cells from microvessels of the newborn human foreskin in cell culture. J. Invest. Dermatol. 75, 316-321.
6. Deryugina, E. I., and Müller-Sieburg, C. E. (1993). Stromal cells in long-term cultures: Keys to the elucidation of hematopoietic development? Crit. Rev. Immunol. 13, 115-150.
7. Dutt, K., Scott, M., Del Monte, M., Agarwal, N., Sternberg, P., Srivastava, S. K., and Srinivasan, A. (1990). Establishment of human retinal pigment epithelial cell lines by oncogenes. Oncogene 5, 195-200.
8. Favaloro, E. J. (1991). CD-13 ('gp150'; aminopeptidase-N): Coexpression on endothelial and haemopoietic cells with conservation of functional activity. Immunol. Cell. Biol. 60, 253-260.
9. Favaloro, E. J., Moraitis, N., Bradstock, K., and Koutts, J. (1990). Co-expression of haemopoietic antigens on vascular endothelial cells: A detailed phenotypic analysis. Br. J. Haematol. 74, 385-394.
10. Fleischman, R. A., Simpson, F., Gallardo, T., Jin, X-L., and Perkins, S. (1995). Isolation of endothelial-like stromal cells that express Kit ligand and support in vitro hematopoiesis. Exp. Hematol. 23, 1407-1416.
11. Guessow, D., Rein, R., Ginjaar, I., Hochstenbach, F., Seemann, G., Kottman, A., and Ploegh, H. L. (1987). The human beta-2-microglobulin gene: Primary structure and definition of the transcriptional unit. J. Immunol. 139, 3132-3138.
12. Kellar, K. L., Hooper, W. C., and Benson, J. M. (1995). MEG-01s cells have receptors for and respond to IL-3, IL-6, and SCF. Exp. Hematol. 23, 557-564.
13. Martin, F. H., Suggs, S. V., Langley, K. E., Lu, H. S., Ting, J., Okino, K. H., Morris, C. F., McNiece, I. K., Jacobsen, F. W., Mendiaz, E. A., Birkett, N. C., Smith, K. A., Johnson, M. J., Parker, V. P., Flores, J. C., Patel, A. C., Fisher, E. F., Erjavec, H. O., Herrera, C. J., Wypych, J., Sachdev, R. K., Pope, J. A., Leslie, I., Wen, D., Lin, C-H., Cupples, R. L., and Zsebo, K. M. (1990). Primary structure and functional expression of rat and human stem cell factor DNAS. Cell 63, 203-211.
14. Paul, S. R., Bennett, F., Calvetti, J. A., Kelleher, K., Wood, C. R., O'Hara, R. M., Jr., Leary, A. C., Sibley, B., Clark, S. C., Williams, D. A., and Yang, Y-C. (1990). Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proc. Natl. Acad. Sci. USA 87, 7512-7516.
15. Pober, J. S., and Cotran, R. S. (1991). What can be learned from the expression of endothelial adhesion molecules in tissues? Lab. Invest. 64, 301-305.
16. Pober, J. S., Gimbrone, M. A., Jr., Cotran, R. S., Reiss, C. S., Burakoff, S. J., Fiers, W., and Ault, K. A. (1983). Ia expression by vascular endothelium is inducible by activated T cells and by human interferon. J. Exp. Med. 157, 1339-1353.
17. Rafii, S., Shapiro, F., Pettengell, R., Ferris, B., Nachman, R. L., Moore, M. A. S., and Asch, A. S. (1995). Human bone marrow microvascular endothelial cells support long term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood 86, 3353-3363.
18. Rafii, S., Shapiro, F., Rimarachin, J., Nachman, R. L., Ferris, B., Weksler, B., Moore, M. A. S., and Asch, A. S. (1994). Isolation and characterization of human bone marrow microvascular endothelial cells: Hematopoietic progenitor cell adhesion. Blood 84, 10-19.
19. Suen, Y., Chang, M., Lee, S. M., Buzby, J. S., and Cairo, M. S. (1994). Regulation of interleukin-11 protein and mRNA expression in neonatal and adult fibroblasts and endothelial cells. Blood 84, 4125-4134.
20. Wang, Y-C., Neckelmann, N., Mayne, A., Herskowita, A., Srinivasan, A., Sell, K. W., and Ahmed-Ansari, A. (1991). Establishment of a human fetal cardiac myocyte cell line. In Vitro Cell. Dev. Biol. 27A, 63-74.
21. Wickenhauser, C., Lorenzen, J., Thiele, J., Hillienhof, A., Jungheim, K., Schmitz, B., Hansmann, M. L., and Fisher, R. (1995). Secretion of cytokines (interleukins-1α, -3, -6 and granulocyte-macrophage colony-stimulating factor) by normal human bone marrow megakaryocytes. Blood 85, 685-691.
22. Xu, Y., Swerlick, R. A., Sepp, N., Bosse, D., Ades, E. W., and Lawley, T. J. (1994). Characterization of expression and modulation of cell adhesion molecules on an immortalized human dermal microvascular endothelial cell line (HMEC-1). J. Invest. Dermatol. 102, 833-837.
23. Yang, Y-C., Ricciardi, S., Ciarletta, A., Calvette, J., Kelleher, K., and Clark, S. C. (1989). Expression cloning of a cDNA encoding a novel human hematopoietic growth factor: Human homologue of murine T-cell growth factor P40. Blood 74, 1880-1884.