메뉴 건너뛰기




Volumn 7, Issue 6, 1996, Pages 651-658

Double-lectin site ricin B chain mutants expressed in insect cells have residual galactose binding: Evidence for more than two lectin sites on the ricin toxin B chain

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BINDING SITES; BIOSYNTHESIS; CELLS; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CYTOTOXICITY; DISEASE CONTROL; MAMMALS; OLIGONUCLEOTIDES; RECOMBINANT PROTEINS; SULFUR COMPOUNDS; X RAY CRYSTALLOGRAPHY;

EID: 0030294020     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc960056b     Document Type: Article
Times cited : (8)

References (29)
  • 1
    • 0015781481 scopus 로고
    • Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
    • Olsnes, S., and Pihl, A. (1973) Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis. Biochemistry 12, 3121-3126.
    • (1973) Biochemistry , vol.12 , pp. 3121-3126
    • Olsnes, S.1    Pihl, A.2
  • 2
    • 0025903320 scopus 로고
    • Studies on the molecular recognition of synthetic methyl β-lactoside analogs by ricin, a cytotoxic plant lectin
    • Rivera-Sagredo, A., Sous, D., Diaz-Maurino, T., Jimenez-Barbero, J., and Martin-Lomas, M. (1991) Studies on the molecular recognition of synthetic methyl β-lactoside analogs by ricin, a cytotoxic plant lectin. Eur. J. Biochem. 197, 217-228.
    • (1991) Eur. J. Biochem. , vol.197 , pp. 217-228
    • Rivera-Sagredo, A.1    Sous, D.2    Diaz-Maurino, T.3    Jimenez-Barbero, J.4    Martin-Lomas, M.5
  • 3
    • 0017074401 scopus 로고
    • Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
    • Olsnes, S., Sandvig, K., Refsnes, K., and Pihl, A. (1976) Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin. J. Biol. Chem. 251, 3985-3992.
    • (1976) J. Biol. Chem. , vol.251 , pp. 3985-3992
    • Olsnes, S.1    Sandvig, K.2    Refsnes, K.3    Pihl, A.4
  • 4
    • 0018078474 scopus 로고
    • Binding of galactose and lactose to ricin: Equilibrium studies
    • Zentz, C., Frenoy, J., and Bourrillon, R. (1978) Binding of galactose and lactose to ricin: equilibrium studies. Biochim. Biophys. Acta 536, 18-26.
    • (1978) Biochim. Biophys. Acta , vol.536 , pp. 18-26
    • Zentz, C.1    Frenoy, J.2    Bourrillon, R.3
  • 5
    • 0018787411 scopus 로고
    • Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides
    • Baenziger, J., and Fiete, D. (1979) Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides. J. Biol. Chem. 254, 9795-9799.
    • (1979) J. Biol. Chem. , vol.254 , pp. 9795-9799
    • Baenziger, J.1    Fiete, D.2
  • 6
    • 0017074398 scopus 로고
    • Kinetics of binding of the toxic lectins abrin and ricin to surface receptors on human cells
    • Sandvig, K., Olsnes, S., and Pihl, A. (1976) Kinetics of binding of the toxic lectins abrin and ricin to surface receptors on human cells. J. Biol. Chem. 251, 3977-3984.
    • (1976) J. Biol. Chem. , vol.251 , pp. 3977-3984
    • Sandvig, K.1    Olsnes, S.2    Pihl, A.3
  • 7
    • 0026699610 scopus 로고
    • Biochemistry of carbohydrate-protein interaction
    • Lee, Y. (1992) Biochemistry of carbohydrate-protein interaction. FASEB J. 6, 3193-3200.
    • (1992) FASEB J. , vol.6 , pp. 3193-3200
    • Lee, Y.1
  • 8
    • 0029064070 scopus 로고
    • Multiplicity of lectin-carbohydrate interactions
    • Drickamer, K. (1995) Multiplicity of lectin-carbohydrate interactions. Nat. Struct. Biol. 2, 437-439.
    • (1995) Nat. Struct. Biol. , vol.2 , pp. 437-439
    • Drickamer, K.1
  • 9
    • 0025939115 scopus 로고
    • Structure of ricin B chain at 2.5 Anstrom resolution
    • Rutenber, E., and Robertus, J. (1991) Structure of ricin B chain at 2.5 Anstrom resolution. Proteins 10, 260-269.
    • (1991) Proteins , vol.10 , pp. 260-269
    • Rutenber, E.1    Robertus, J.2
  • 10
    • 0022787505 scopus 로고
    • Identification of the tryptophan residue located at the low-affinity saccharide binding site of ricin D
    • Hatakeyama, T., Yamasaki, N., and Funatsu, G. (1986) Identification of the tryptophan residue located at the low-affinity saccharide binding site of ricin D. J. Biochem. 100, 781-788.
    • (1986) J. Biochem. , vol.100 , pp. 781-788
    • Hatakeyama, T.1    Yamasaki, N.2    Funatsu, G.3
  • 11
    • 0019513151 scopus 로고
    • Studies on the galactose-binding site of ricin and the hybrid toxin Man6P-ricin
    • Youle, R., Murray, J., and Neville, D. (1981) Studies on the galactose-binding site of ricin and the hybrid toxin Man6P-ricin. Cell 23, 551-559.
    • (1981) Cell , vol.23 , pp. 551-559
    • Youle, R.1    Murray, J.2    Neville, D.3
  • 12
    • 0025882239 scopus 로고
    • The galactose-binding sites of the cytotoxic lectin ricin can be chemically blocked in high yield with reactive ligands prepared by chemical modification of glycopeptides containing triantennary N-linked oligosaccharides
    • Lambert, J., McIntyre, G., Gauthier, M., Zullo, D., Rao, V., Steeves, R., Goldmacher, V., and Blattler, W. (1991) The galactose-binding sites of the cytotoxic lectin ricin can be chemically blocked in high yield with reactive ligands prepared by chemical modification of glycopeptides containing triantennary N-linked oligosaccharides. Biochemistry 30, 3234-3247.
    • (1991) Biochemistry , vol.30 , pp. 3234-3247
    • Lambert, J.1    McIntyre, G.2    Gauthier, M.3    Zullo, D.4    Rao, V.5    Steeves, R.6    Goldmacher, V.7    Blattler, W.8
  • 13
    • 0025341724 scopus 로고
    • Expression and functional properties of genetically engineered ricin B chain lacking galactose-binding activity
    • Vitetta, E., and Yen, N. (1990) Expression and functional properties of genetically engineered ricin B chain lacking galactose-binding activity. Biochim. Biophys. Acta 1049, 151-157.
    • (1990) Biochim. Biophys. Acta , vol.1049 , pp. 151-157
    • Vitetta, E.1    Yen, N.2
  • 14
    • 0025986485 scopus 로고
    • Mutational analysis of the galactose binding ability of recombinant ricin B chain
    • Wales, R., Richardson, P., Roberts, L., Woodland, H., and Lord, J. (1991) Mutational analysis of the galactose binding ability of recombinant ricin B chain. J. Biol. Chem. 266, 19172-19179.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19172-19179
    • Wales, R.1    Richardson, P.2    Roberts, L.3    Woodland, H.4    Lord, J.5
  • 15
    • 0026605274 scopus 로고
    • Phage display of ricin B chain and its single binding domains: System for screening galactose-binding mutants
    • Swimmer, C., Lehar, S., McCafferty, J., Chiswell, D., Blattler, W., and Guild, B. (1992) Phage display of ricin B chain and its single binding domains: system for screening galactose-binding mutants. Proc. Natl. Acad. Sci. U.S.A. 89, 3756-3760.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 3756-3760
    • Swimmer, C.1    Lehar, S.2    McCafferty, J.3    Chiswell, D.4    Blattler, W.5    Guild, B.6
  • 17
    • 0028537938 scopus 로고
    • Expression of oligohistidine-tagged ricin B chain in Spodoptera frugiperda
    • Afrin, L., Gulick, H., Vesely, J., Willingham, M., and Frankel, A. (1994) Expression of oligohistidine-tagged ricin B chain in Spodoptera frugiperda. Bioconjugate Chem. 5, 539-546.
    • (1994) Bioconjugate Chem. , vol.5 , pp. 539-546
    • Afrin, L.1    Gulick, H.2    Vesely, J.3    Willingham, M.4    Frankel, A.5
  • 21
    • 0025057944 scopus 로고
    • High-efficiency oligonucleotide-directed plasmid mutagenesis
    • Olson, D., and Eckstein, F. (1990) High-efficiency oligonucleotide-directed plasmid mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 87, 1451-1455.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 1451-1455
    • Olson, D.1    Eckstein, F.2
  • 24
    • 0023079174 scopus 로고
    • The complete amino acid sequence of ricin B-chain of ricin E isolated from small-grain castor bean seeds. Ricin E is a gene recombination product of ricin D and Ricinus communis agglutinin
    • Araki, T., and Funatsu, G. (1987) The complete amino acid sequence of ricin B-chain of ricin E isolated from small-grain castor bean seeds. Ricin E is a gene recombination product of ricin D and Ricinus communis agglutinin. Biochim. Biophys. Acta 911, 191-200.
    • (1987) Biochim. Biophys. Acta , vol.911 , pp. 191-200
    • Araki, T.1    Funatsu, G.2
  • 25
    • 0015972554 scopus 로고
    • Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ridnus communis
    • Olsnes, S., Saltvedt, E., and Pihl, A. (1974) Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ridnus communis. J. Biol. Chem. 249, 803-810.
    • (1974) J. Biol. Chem. , vol.249 , pp. 803-810
    • Olsnes, S.1    Saltvedt, E.2    Pihl, A.3
  • 26
    • 0020490555 scopus 로고
    • Binding of two molecules of 4-methylumbelliferyl galactose or 4-methylumbelliferyl N-acetylgalactosamine to the B chains of ricin and Ricinus communis agglutinin and to purified ricin B chain
    • Houston, L., and Dooley, T. (1982) Binding of two molecules of 4-methylumbelliferyl galactose or 4-methylumbelliferyl N-acetylgalactosamine to the B chains of ricin and Ricinus communis agglutinin and to purified ricin B chain. J. Biol. Chem. 257, 4147-4151.
    • (1982) J. Biol. Chem. , vol.257 , pp. 4147-4151
    • Houston, L.1    Dooley, T.2
  • 27
    • 0026782106 scopus 로고
    • Correlation between in vivo toxicity and preclinical in vitro parameters for the immunotoxin anti-B4-blocked ricin
    • Grossbard, M., Lambert, J., Goldmacher, V., Blattler, W., and Nadler, L. (1992) Correlation between in vivo toxicity and preclinical in vitro parameters for the immunotoxin anti-B4-blocked ricin. Cancer Res. 52, 4200-4207.
    • (1992) Cancer Res. , vol.52 , pp. 4200-4207
    • Grossbard, M.1    Lambert, J.2    Goldmacher, V.3    Blattler, W.4    Nadler, L.5
  • 28
    • 0026563849 scopus 로고
    • The specific cytotoxicity of immunoconjugate containing blocked ricin is dependent on the residual binding capacity of blocked ricin: Evidence that the membrane binding and A-chain translocation activities of ricin cannot be separated
    • Goldmacher, V., Lambert, J., and Blattler, W. (1992) The specific cytotoxicity of immunoconjugate containing blocked ricin is dependent on the residual binding capacity of blocked ricin: evidence that the membrane binding and A-chain translocation activities of ricin cannot be separated. Biochem. Biophys. Res. Commun. 183, 758-766.
    • (1992) Biochem. Biophys. Res. Commun. , vol.183 , pp. 758-766
    • Goldmacher, V.1    Lambert, J.2    Blattler, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.