Sequence analysis of LYS49 phospholipase A2 myotoxins: A highly conserved class of proteins

Toxicon

Volumn 34, Issue 11-12, 1996, Pages 1237-1242

  Selistre De Araujo, Heloisa S ^a,b   White, Steven P ^a   Ownby, Charlotte L ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTOXIN; PHOSPHOLIPASE A2; SNAKE VENOM;

CONFERENCE PAPER; ENZYME ANALYSIS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; SEQUENCE ANALYSIS;

AGKISTRODON; AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; CROTALID VENOMS; LYSINE; MOLECULAR SEQUENCE DATA; NEUROTOXINS; PHOSPHOLIPASES A; SEQUENCE ANALYSIS, DNA;

EID: 0030293803     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(96)00111-0     Document Type: Conference Paper

References (31)

1. Bouchier, C., Ducancel, F., Guignery-Frelat, G., Bon, C., Boulain, J.-C. and Menez, A. (1988) Cloning and sequencing of cDNAs encoding the two subunits of crotoxin. Nucl. Acids Res. 16, 9050.
2. Cardin, A. D. and Weintraub, H. J. R. (1989) Molecular modeling of protein-glycosaminoglycan interactions. Arteriosclerosis 9, 21-32.
3. Cintra, A. C. O., Marangoni, S., Oliveira, B. and Giglio, J. R. (1993) Bothropstoxin-I: amino acid sequence and function. J. Prot. Chem. 12, 57-64.
4. 2. J. biol. Chem. 269, 13057-13060.
5. 2. Arch. Biochem. Biophys. 284, 352-359.
6. 2 isozymes from Trimeresurus gramineus (green habu snake) venom. Toxicon 31, 957-967.
7. 2 from the venom of Vipera russelli. Toxicon 32, 665-673.
8. 2-α from the venom of Crotalus adamanteus. J. biol. Chem. 252, 4913-4921.
9. 2 from the venom of the cottonmouth snake at 2.0 Anstroms resolution. J. biol. Chem. 265, 17649-17656.
10. Homsi-Brandeburgo, M. I., Queiroz, L. S., Neto, H. S., Simioni, L. R. and Giglio, J. R. (1988) Fractionation of Bothrops jararacussu snake venom: partial chemical characterization and biological activity of bothropstoxin. Toxicon 26, 615-627.
11. John, T. R., Smith, L. A. and Kaiser, I. I. (1994) Genomic sequences encoding the acidic and basic subunits of mojave toxin: unusually high sequence identity of non-coding regions. Gene 139, 229-234.
12. Johnson, E. K. and Ownby, C. L. (1993) Isolation of a myotoxin from the venom of Agkistrodon contortrix laticinctus (broad-banded copperhead) and pathogenesis of myonecrosis induced by it in mice. Toxicon 31, 243-255.
13. Kaiser, I. I., Gutiérrez, J. M., Plummer, D., Aird, S. D. and Odell, G. V. (1990) The amino acid sequence of a myotoxic phospholipase from the venom of Bothrops asper. Arch. Biochem. Biophys. 278, 319-325.
14. 2, Biochem. Int. 28, 895-903.
15. Kondo, K., Zhang, J., Xu, K, and Kagamiyama, H. (1989) Amino acid sequence of a presynaptic neurotoxin, agkistrodotoxin, from the venom of Agkistrodon halys Pallas. J. Biochem. 105, 196-203.
16. 2 with low activity, from Trimeresurus flavoviridis venom. J. Biochem. 107, 400-408.
17. 2 homolog from the venom of Trimeresurus mucrosquamatus. Biochim. biophys. Acta 1077, 362-370.
18. 2 from Bothrops asper snake venom by glycosaminoglycans of the heparin/heparan sulfate family. Biochem. Pharmac. 47, 1509-1518.
19. 2. J. biol. Chem. 261, 4797-4804.
20. Mebs, D. and Ownby, C. L. (1990) Myotoxic components of snake venous: their biochemical and biological activities. Pharmac. Ther. 48, 223-236.
21. Melo, P. A., Homsi-Brandeburgo, M. I., Giglio, J. R. and Suarez-Kurtz, G. (1993) Antagonism of the myotoxic effects of Bothrops jararacussu venom and bothropstoxin by polyanions. Toxicon 31, 285-291.
22. 2s may imply gene duplications. J. molec. Evol. 41, 174-179.
23. 2 isozymes. Proc. natn. Acad. Sci. U.S.A. 89, 8557-8561.
24. 2-terminal region. J. biol. Chem. 257, 2155-2159.
25. 2 from bovine pancreas and Crotalus atrox venom. J. biol. Chem. 260, 11627-11634.
26. Rosenberg, P. (1990) Phospholipases. In: Handbook of Toxinology, pp. 67-277 (Shier, W. T. and Mebs, D., Eds). New York: Marcel Dekker.
27. 2 from the venom of Agkistrodon piscivorus piscivorus. J. biol. Chem. 267, 22645-22657.
28. 2 myotoxin from Agkistrodon contortrix laticinctus snake venom. Arch. Biochem. Biophys., 326, 21-30.
29. 2 completed with micelles and a competitive inhibitor. J. biomol. N.M.R. 5, 110-121.
30. 2. Role of histidine and calcium ion in the catalytic mechanism. Biochemistry 19, 743-750.
31. 2 with low activity, from the venom of Trimeresurus flavoviridis (habu snake). Toxicon 28, 43-54.