A rat model for sickle cell-mediated vaso-occlusion in retina

Microvascular Research

Volumn 52, Issue 3, 1996, Pages 270-280

  Lutty, Gerard A ^a   Phelan, Ann ^b   McLeod, D Scott ^a   Fabry, Mary E ^c   Nagel, Ronald L ^c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GAS ANALYSIS; HYPOXIA; MALE; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RETINA VEIN OCCLUSION; RETINOPATHY; SICKLE CELL ANEMIA;

ANIMALIA; LAREX;

EID: 0030292805     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1006/mvre.1996.0064     Document Type: Article

References (28)

1. Aldrich, T. K., Dhuper, S., Patwa, N. S., Makolo, E., Suzuka, A., Najeebi, S. A., Santhanakrishnan, S., Nagel, R. L., and Fabry, M. E. (1996). Pulmonary entrapment of sickle cells: The role of regional alveolar hypoxia. J. Appl. Physiol. 80, 531-539.
2. Ballas, S. K. (1992). Red blood cell changes during the evolution of the sickle cell painful crises. Blood 79, 2154-2163.
3. Bertles, J. F., and Milner, F. A. (1968). Irreversibly sickled erythrocytes: A consequence of the heterogeneous distribution of hemoglobin types in sickle-cell anemia. J. Clin. Invest. 47, 1731-1741.
4. Butcher, E. C., and Weissman, I. L. (1980). Direct fluorescent labeling of cells with fluorescein or rhodamine isothiocyanate. I. Technical aspects. J. Immunol. Methods 37, 97-108.
5. Eaton, W. A., and Hofrichter, J. (1994). Sickle hemoglobin polymerization. In Sickle Cell Disease: Basic Principles and Clinical Practice (S. H. Embury, R. P. Hebbel, N. Mohandas, and M. H. Steinberg, Eds.), pp. 53-87. Raven Press, New York.
6. Fabry, M. E., Benjamin, L., Lawrence, C., and Nagel, R. L. (1984). An objective sign in painful crisis in sickle cell anemia: The concomitant reduction of high density red cells. Blood 64, 559-563.
7. Fabry, M. E., Fine, E., Rajanayagam, V., Factor, S. M., Gore, J., Sylla, M., and Nagel, R. (1992). Demonstration of endothelial adhesion sickle cells in vivo: A distinct role for deformable sickle cell discocytes. Blood 79, 1602-1611.
8. Fabry, M. E., Mears, J. G., Patel, P., Schaefer-Rego, K., Carmichael, L. D., Martinez, G., and Nagel, R. L. (1984). Dense cells in sickle cell anemia: The effects of gene interaction. Blood 64, 1042-1046.
9. 1H magnetic resonance imaging changes. Proc. Natl. Acad. Sci. USA 86, 3808-3812.
10. Goldberg, M. F. (1976). Retinal vaso-occlusion in sickling hemoglobinopathies. Birth Defects 12, 475-515.
11. Goldberg, M. F. (1977). Retinal neovascularization in sickle cell retinopathy. Trans. Am. Acad. Ophthalmol. Otolaryngol. 83, 409-431.
12. Hickam, J. B., and Frayser, R. (1966). Studies of the retinal circulation in man. Observations on vessel diameter, arteriovenous oxygen difference, and mean circulation time. Circulation 33, 302-316.
13. Kaul, D., Fabry, M., and Nagel, R. (1989a). Microvascular sites and characteristics of sickle cell adhesion to vascular endothelium in shear flow conditions: Pathophysiological implications. Proc. Natl. Acad. Sci. USA 86, 3356-3360.
14. Kaul, D., Fabry, M., Windisch, P., Baez, S., and Nagel, R. (1983). Erythrocytes in sickle cell anemia are heterogeneous in their rheological and hemodynamic characteristics. J. Clin. Invest. 72, 22-31.
15. Kaul, D. K., Fabry, M. E., and Nagel, R. L. (1989b). Erythrocytic and vascular factors influencing the microcirculatory behavior of blood in sickle cell anemia. Ann. N.Y. Acad. Sci. 565, 316-326.
16. Klug, P. P., and Lessin, L. S. (1977). Microvascular blood flow of sickled erythrocytes. Blood Cells 3, 263-272.
17. La Celle, P. L. (1977). Oxygen delivery to muscle cells during capillary occlusion by sickled erythrocytes. Blood Cells 3, 273-282.
18. Lutty, G. A., and McLeod, D. S. (1992). A new technique for visualization of the human retinal vasculature. Arch. Ophthalmol. 110, 267-276.
19. Lutty, G. A., Phelan, A., McLeod, D. S., Merges, C., Suzuka, S. M., Fabry, M. E., and Nagel, R. L. (1996). A rat model for retinal vascular occlusion by human sickle erythrocytes. Invest. Ophthalmol. Vis. Sci. 37, S659.
20. McLeod, D., Goldberg, M., and Lutty, G. (1993). Dual perspective analysis of vascular formations in sickle cell retinopathy. Arch. Ophthalmol. 111, 1234-1245.
21. Mozzarelli, A., Hofrichter, J., and Eaton, W. A. (1987). Delay time of hemoglobin S polymerization prevents most cells from sickling in vivo. Science 237, 500-506.
22. Powars, D. R. (1994). Natural history of disease: The first two decades. In Sickle Cell Disease: Basic Principles and Practice (S. H. Embury, R. P. Hebbel, N. Mohandas, and M. H. Steinberg, Eds.), pp. 395-412. Raven Press, New York.
23. Raichand, M., Goldberg, M. F., Nagpal, K. C., Goldbaum, M. H., and Asdourian, G. K. (1977). Evolution of neovascularization in sickle cell retinopathy. Arch. Ophthalmol. 95, 1543-1552.
24. Serjeant, B. E., Mason, K. P., Acheson, R. W., Maude, G. H., Stuart, J., and Serjeant, G. R. (1986). Blood rheology and proliferative retinopathy in homozygous sickle cell disease. Br. J. Ophthalmol. 70, 522-525.
25. Serjeant, G. R. (1985). Sickle Cell Disease. Oxford Univ. Press, Oxford.
26. Vadas, M. A., Gamble, J. R., and Smith, W. B. (1992). Regulation of myeloid blood cell - endothelial interaction by cytokines. In Adhesion. Its Role in Inflammatory Disease (J. M. Harlan and D. Y. Liu, Eds.), pp. 65-81. Freeman, New York.
27. Voelkel, N. F. (1986). Mechanisms of hypoxic pulmonary vasoconstriction. Am. Rev. Respir. Dis. 133, 1186-1195.
28. Wise, G. N., Dollery, C. T., and Henkind, P. (1971). The Retinal Circulation. Harper and Row, New York.