Solution structure of vaso-active intestinal polypeptide (11-28)-NH2, a fragment with analgesic properties

Peptide Research

Volumn 9, Issue 6, 1996, Pages 327-331

  Haghjoo, K ^a   Cash, P W ^a,b   Farid, R S ^a,b   Komisaruk, B R ^a,b   Jordan, F ^a   Pochapsky, S S ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b Bruker Instruments Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; PEPTIDE FRAGMENT; VASOACTIVE INTESTINAL PEPTIDE (11 28) NH2; VASOACTIVE INTESTINAL PEPTIDE (11-28)-NH2; VASOACTIVE INTESTINAL POLYPEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

AMINO ACID SEQUENCE; ANALGESICS; CIRCULAR DICHROISM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0030291920     PISSN: 10405704     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Anand, P, S.J. Gibson, G.P. McGregor, M.A. Blank, M.A. Ghatel, A.J. Bacarese-Hamilton, J.M. Polak and S.R. Bloom. 1983. A VIP-containing system concentrated in the lumbosacral region of the human spinal cord. Nature .305:143-145.
2. Barbato, G., F. Jordan and B.R. Komisaruk. 1988. The in vitro proteolytic processing of vasoactive intestinal polypeptide by rat spinal cord homogenate. Ann. N.Y. Acad. Sci. 527:582-585.
3. Basbaum, A.I. and E.J. Glazer. 1983. Immunoreactive vasoactive intestinal polypeptide is concentrated in the sacral spinal cord: a possi-ble marker for pelvic visceral afferent fibers. Somatosens. Res. 7:69-82.
4. Braunschweiler, L. and R.R. Ernst, 1983. Coherence transfer by isotropic mixing: application to proton correlation spectroscopy. J. Magn. Reson. 5J:521-528.
5. Carlquist, M., V. Mutt and H. Jornvall. 1979. Isolation and characterization of bovine vasoactive intestinal peptide (VIP). FEES Lett. 108:457-460.
6. Caughey, G.H., F. Leidig, N.F. Viro and J.A. Nadel. 1988. Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase. J. Pharmacol. Exp. Ther. 244:133-137.
7. Chen, Y.H., J.T. Yang and H.M. Martinez. 1972. Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion. Biochemistry //:4120-4131.
8. Chou, P.Y. and G.D. Fasman. 1978. Empirical predictions of protein conformation. Annu. Rev. Biochem. 47:251-276.
9. Colombo, R.A. 1982. A new solid-phase synthesis of porcine vasoactive intestinal peptide using yV-9-fluorenylmethyloxy carbonyl amino acids. Experientia 38:173-175.
10. Conde, D. and B.R. Komisaruk. 1996. Effects of VIP(ll-28)-NH2 and naloxone on analgesia in rats. Soc. Neurosci. Abst. 22:1367.
11. Coy, D.H. and J. Gardner. 1980. Solid-phase synthesis of porcine vasoactive intestinal peptide. Int. J. Pept. Protein Res. /5:73-78.
12. Emson, P.C., R.F.T. Gilbert, I. Loren, J. Fahrenkrug, F. Sundler and O.B. Schaffalitsky de Muckadell. 1979. Development of vasoactive intestinal polypeptide (VIP) containing neurons in the rat brain. Brain Res. / 77:437-444.
13. Fournier, A., J.K. Saunders and S. St-Pierre. 1982. Synthesis, conformational studies and biological activities of VIP and related fragments. Peptides 5:169-177.
14. Fry, D.C., V.S. Madison, D.R. Bolin, D.N. Greeley, V. Toome and B.B. Wegrzynski. 1989. Solution structure of an analog of vasoactive intestinal peptide as determined by two-dimensional NMR and circular dichroism spectroscopies and constrained molecular dynamics. Biochemistry 2 2399-2409.
15. Gibson, S.J., J.M. Polak, P. Anand, M.A. Blank, S.R. Bloom. 1984. The distribution and origin of VIP in the spinal cord of six mammalian species. Peptides 5:201-207.
16. Goetzl, E.J., S.P. Sreedharan, C.W. Turck, R. Bridenbaugh and B. Malfroy. 1989. Preferential cleavage of amino- and carboxyl-terminal oligopeptides from vasoactive intestinal polypeptide by human recombinant enkephalinase. Biochem. Biophys. Res. Commun. 755:850-854.
17. Greenfield, N. and G.D. Fasman. 1969. Computed circular dichroism spectra for the evaluation of protein conformation. Biochemistry 8:4108-4116.
18. Itoh, N., K. Obata, N. Yanaihara and K. Okamoto. 1983. Human preprovasoactive intestinal polypeptide contains a novel PHI-27like peptide, PHM-27. Nature 304:547-549.
19. Komisaruk, B.R., C. Banas, S.B. Heller, B. Whipple, G.F. Barbato and F. Jordan. 1988. Analgesia produced by vasoactive intestinal polypeptide administered directly to the spinal cord in rats. Ann. N.Y. Acad. Sci. 527:650654.
20. Komisaruk, B.R. 1990. Vaginocervical afference as a trigger for analgesic, behavioral, autonomie and neuroendocrine processes, p. 123-137. In T. Archer and S. Hansen (Eds.), Behavioral Biology: Neuroendocrine Axis. Lawrence Erlbaum Assoc., Publ., Hillsdale. NJ.
21. Komisaruk, B.R., C. Banas, A. Mehta, P.W. Cash, B. Whipple and F. Jordan. 1990. Analgesic effect of synthetic fragments of vasoactive intestinal peptide in the rat. Soc. Neurosci. Abst. /6:565.
22. Komisaruk, B.R. and F. Jordan, inventors. 1995. Process for Inducing Analgesia, Peptides and Therapeutic Compositions. US patent 5.426,099.
23. Kumar, A., R.R. Ernst and K. Wiithrich. 1980. A two-dimensional nuclear Overhauser enhancement (2D-NOE) experiment for the elucidation of complete proton-proton crossrelaxation networks in biological macromolecules. Biochem. Biophys. Res. Commun. 95:1 -6.
24. Larsson, L.I., J. Fahrenkrug, O.B. Schaffalitzky de Muckadell, F. Sundler, R. Hakanson and J.F. Rehfeld. 1976. Localization of vasoactive intestinal polypeptide (V1P) to central and peripheral neurons. Proc. Natl. Acad. Sci. USA 73:3197-3200.
25. Mutl, V. and S.I. Said. 1974. Structure of the porcine vasoactive intestinal octacosapeptide. Eur. J. Pharmacol. 42:581-589.
26. Nadelhaft, I. 1983. The distribution of vasoactive intestinal polypeptide (VIP) in the lumbosacral spinal cord of the rat. Soc. Neurosci. Abst. 9:293.
27. Paul, S., D.J. Voile, C.M. Beach, D.R. Johnson, M.J. Powell and R.J. Massey. 1989. Catalytic hydrolysis of vasoactive intestinal peptide by human autoantibody. Science 244:1158-1162.
28. Paul, S., M. Sun, R. Mody, T.H. Tewary, P. Stemmer, R.J. Massey, T. Gianferrara, S. Mehrotra, T. Dreyer, M. Meldal and A. Tramontane. 1992. A peptidolytic monoclonal antibody elicited by a neuropeptide. J. Biol. Chem. 267:13142-13145.
29. Robinson, R.M., E.W. Blakeney and W.L. Mattice. 1982. Lipid-induced conformational changes in glucagon, secretin and vasoactive intestinal peptide. Biopolymers 27:1217-1228.
30. Roppolo, J.R., I. Nadelhaft and W.C. deGroat. 1983. The preferential distribution of vasoactive intestinal polypeptide (VIP) in the sacral spinal cord of the rhesus monkey. Soc. Neurosci. Abstr. 9:292.
31. Said, S.I. and V. Mutt. 1970. Polypeptide with broad biological activity: isolation from small intestine. Science 709:1217-1218.
32. Said, S.I. and V. Mutt. 1977. Relationship of spasmogenic and smooth muscle relaxant peptides from normal lung to other vasoactive compounds. Nature 265:84-86.
33. Sheward, W.J., E.M. Lutz and A.J. Harmar. 1995. The distribution of vasoactive intestinal peptide receptor messenger RNA in the rat brain and pituitary gland as assessed by in situ hybridization. Neuroscience 67:409-418.
34. Wang, S.C. and B.H. Du. 1985. Purification of dog V1P from a single animal. Life Sci. 37:979-983.
35. Wider, G., S. Macura, A. Kuniar. R.R. Ernst and K. Wiithrich. 1984. Homonuclear two-dimensional 'H NMR of proteins. Experimental procedures. J. Magn. Reson. 56:207234.
36. Wokaun, A. and R.R. Ernst. 1977. Selective detection of multiple quantum transitions in NMR by two-dimensional spectroscopy. Chem. Phys. Lett. 52:407-412.
37. Woody, R.W. 1996.Theory of Circular Dichroism of Proteins, p. 25-67. In G.D. Fasman (Ed.), Circular Dichroism and Conformational Analysis of Biomolecules. Plenum Press, New York.
38. Yaksh, T.L. and T.A. Rudy. 1976. Chronic catheterization of the subarachnoid space. Physiol. Behav. 77:1031-1036.
39. Yoshida, T., A.M. Geumei, R.J. Schmitt and S.I. Said. 1974. Vasoactive intestinal peptide: a potent coronary vasodilator. Fed. Proc. 33:378.