TCRalpha/beta and TCRgamma/delta CD4-/CD8- HLA-DR alloreactive CTL clones do not use FAS/FAS ligand pathway to lyse their specific target cells

Human Immunology

Volumn 51, Issue 1, 1996, Pages 13-22

  Mami Chouaib, Fathia ^a,b   Flament, Caroline ^b   Asselin Paturel, Carine ^a   Gaudin, Catherine ^b   Chouaib, Salem ^a  

^a CJF   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR; FAS ANTIGEN; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ARTICLE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; HLA SYSTEM; IMMUNOGENETICS; LYMPHOCYTE CLONE; LYSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; TARGET CELL; CELL CLONE; CELL LINE; HUMAN; IMMUNOLOGY; PHYSIOLOGY;

ANTIGENS, CD4; ANTIGENS, CD8; ANTIGENS, CD95; CELL LINE; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; LIGANDS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0030281510     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(96)00164-4     Document Type: Article

References (31)

1. 1. Kagi D, Vigaux F, Ledermann B, Burki K, Depraetere V, Nagata S, Hengartner H, Golstein P: Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity. Science 265:528, 1994.
2. 2. Kojima H, Shinohara N, Hanaoka S, Someya-Shirota Y, Takagaki Y, Ohno H, Saito T, Katayama T, Yagita H, Okumura K, et al.: Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1:357, 1994.
3. 3. Lowin B, Hahne M, Mattmann C, Tschopp J: Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways Nature 370:650, 1994.
4. 4. Henkart PA: Lymphocyte-mediated cytotoxicity: Two pathways and multiple effector molecules. Immunity 1: 343, 1994.
5. 2--independent T cell-mediated cytotoxicity. J Exp Med 177:195, 1993.
6. 6. Hanabuchi S, Koyanagi M, Kawasaki A, Shinohara N, Matsuzawa A, Nishimura Y, Kobayashi Y, Yonehara S, Yagita H, Okumura K: Fas and its ligand in a general mechanism of T-cell-mediated cyrotoxicity. Proc Natl Acad Sci 91:4930, 1994.
7. 7. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Has A, Seto Y, Nagata S: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233, 1991.
8. 8. Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, et al.: Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily: Sequence identity with the Fas antigen. J Biol Chem 267:10709, 1992.
9. 9. Suda T, Takahashi T, Goltein P, Nagata S: Molecular cloning and expression of the Fas ligand: A novel member of the tumor necrosis factor family. Cell 75:1169, 1993.
10. 10. Takahashi T, Tanaka M, Inazawa J, Abe T, Suda T, Nagata S: Human Fas ligand: Gene structure, chromosomal location and species specificity. Int Immunol 6:1567, 1994.
11. 11. Tanaka M, Suda T, Takahashi T, Nagata S: Expression of the functional soluble form of human Fas ligand in activated lymphocytes. EMBO J 14:1129, 1995.
12. 12. Ramsdell F, Seaman MS, Miller RE, Picha KS, Kennedy MK, Lynch D: Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death. Int Immunol 6:1545, 1994.
13. 13. Suda T, Okazaki T, Naito Y, Yokota T, Arai N, Ozaki S, Nakao K, Nagata S: Expression of Fas ligand in cells of T cell lineage. J Immunol 154:3806, 1995.
14. + cytotoxic T cells. Proc Natl Acad Sci 91:4185, 1994.
15. 15. Stalder T, Hahn S, Erb P: Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J Immunol 152:1127, 1993.
16. 16. Flament C, Benmerah A, Bonneville M, Triebel F, Mami-Chouaib F: Human TCR-gamma/delta alloreactive response to HLA-DR molecules: Comparison with response of TCR-alpha/beta. J Immunol 153:2890, 1994.
17. 17. Miossec C, Faure F, Ferradini L, Roman-Roman S, Jitsukawa S, Ferrini S, Moretta A, Triebel F, Hercend T: Further analysis of the T cell receptor gamma/delta+ peripheral lymphocyte subset: The Vdeltal gene segment is expressed with either Calpha or Cdelta. J Exp Med 171: 1171, 1990.
18. 18. Brodsky FM, Parham P: Monomorphic anti-HLA-A, B, C monoclonal antibodies detecting molecular subunits and combinatorial determinants. J Immunol 128:129, 1982.
19. 19. Todd RF, Meuer SC, Romain PL, Schlossman SF: A monoclonal antibody that blocks class II histocompatibility related immune interactions. Human Immunology 10: 23, 1984.
20. 20. Watson AJ, DeMars R, Trowbridge IS, Bach FH: Detection of a novel human class II HLA antigen. Nature 304: 358, 1983.
21. 21. Accolla RS, McDonald AP, Corte G, Gross N, Carrel S: Demonstration at the single-cell level of the existence of distinct clusters of epitopes in two predefined human Ia molecular subsets. Eur J Immunol 12:166, 1982.
22. 22. Marti GE, Kuo MC, Shaw S, Chang CC, Demars R, Sogn JA, Coligan JE, Kindt TJ: A novel HLA-D/DR-like antigen specific for human B lymphoid cells. J Exp Med 158:1924, 1983.
23. 23. Walsh CM, Glass AA, Chiu V and Clark WR: The role of the Fas lytic pathway in a perforin-less CTL hybridoma. J Immunol 153:2506, 1994.
24. 24. Chomczynski P, Sacchi N: Single step of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Analytical Biochem 162:156, 1987.
25. 25. Chouaib S, Chehimi J, Bani L, Genetet N, Tursz T, Gay F, Trinchieri G, Mami-Chouaib F: Interleukin 12 induces the differentiation of major histocompatibility complex classI-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors. Proc Natl Acad Sci USA 91:12659, 1994.
26. 26. Chiu VK, Walsh CM, Liu CC, Reed JC, Clark WR: Bcl-2 blocks degranulation but not fas-based cell-mediated cytotoxicity. J Immunol 154:2023, 1995.
27. 27. Vignaux F, Vivier E, Malissen B, Depraetere V, Nagata S, Goltein P: TCR/CD3 coupling to Fas-based cytotoxicity. J Exp Med 181:781, 1995.
28. 28. Carter LL, Dutton RW: Relative perforin- and Fas-mediated lysis in T1 and T2 CD8 effector populations. J Immunol 155:1028, 1995.
29. 29. Kagi D, Ledermann B, Bürki K, Seiler P, Odermatt B, Olsen KJ, Podack ER, Zinkernagel RM, Hengartner H: Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369: 31, 1994.
30. 30. Arase H, Arase N, Kobayashi Y, Nishimura Y, Yonehara S, Onoé K: Cytotoxicity of fresh NK1.1 + T cell receptor alpha/beta+ thymocytes against a CD4+CD8+ thymocyte population associated with intact antigen expression on the target. J Exp Med 180:423, 1994.
31. 31. Arase H, Arase N, Saito T: Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 181:1235, 1995.