The role of antioxidants in nutritional support

Proceedings of the Nutrition Society

Volumn 55, Issue 3, 1996, Pages 945-961

  Fürst, Peter ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; FREE RADICAL;

DIET; DRUG ANTAGONISM; HUMAN; NUTRITIONAL SUPPORT; REVIEW;

ANTIOXIDANTS; DIET; FREE RADICALS; HUMANS; NUTRITIONAL SUPPORT;

EID: 0030280864     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/PNS19960091     Document Type: Conference Paper

References (90)

1. Ames, B. N., Shigenaga, M. K. & Hagen, T. M. (1992). Oxidants, antioxidants, and the degenerative diseases of aging. Proceedings of the National Academy of Sciences, USA 90, 7915-7922.
2. Aruoma, O. I., Kaur, H. & Halliwell, B. (1991). Oxygen free radicals and human diseases. Journal of the Royal Society of Health 111, 172-177.
3. Askanazi, J., Carpentier, Y. A., Michelsen, C. B., Elwyn, D. H., Fürst, P., Kantrowitz, L. R., Gump, F. E. & Kinney, J. M. (1980). Muscle and plasma amino acids following injury. Influence of intercurrent infection. Annals of Surgery 192, 78-85.
4. Babior, B. M. (1978). Oxygen-dependent microbial killing by phagocytes. New England Journal of Medicine 298, 659-668.
5. Babior, B. M., Curnutte, J. T. & Okamura, N. (1988). The respiratory burst oxidase of the human neutrophil. In Oxygen Radicals and Tissue Injury Symposium (Proceedings), pp. 43-48 [B. Halliwell, editor]. Bethesda: Federation of American Societies for Experimental Biology.
6. Banks, M. A., Porter, D. W., Martin, W. G. & Castranova, V. (1992). Taurine protects against oxidant injury to rat alveolar pneumocytes. In Taurine: Nutritional Value and Mechanisms of Action, pp. 341-354 [J. B. Lombardini, S. W. Schaffer and J. Azuma, editors]. New York: Plenum Press.
7. Beckman, J. S., Beckman, T. W. & Chen, J. (1990). Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proceedings of the National Academy of Sciences, USA 87, 1620-1624.
8. Bergström, J., Alvestrand, A., Fürst, P. & Lindholm, B. (1989). Sulphur amino acids in plasma and muscle in patients with chronic renal failure: evidence for taurine depletion. Journal of Internal Medicine 226, 189-194.
9. Biesalski, H. K., Böhles, H., Esterbauer, H., Fürst, P., Gey, F., Hunsdörfer, Kasper, H., Sies, H. & Weisburger, J. (1995). Antioxidative Vitamine in der Prevention (Antioxidative vitamins in prevention). Deutsches Ärzteblatt 18, 1316-1321.
10. Biesalski, H. K., Halmágyi, M. & Fürst, P. (1994). Marginale Vit.-A-Mangelzustände als mögliche Ursache respiratorischer Komplikationen bei Intensivpatienten (Marginal vitamin A deficiency states as possible causes of respiratory complications in intensive care patients). Aktuelle Ernährungsmedizin 19, 54 Abstr.
11. Birt, D. F. & Bresnick, E. (1991). Chemoprevention by non-nutrient components of vegetables and fruit. In Cancer and Nutrition, pp. 221-260 [R. B. Alfin-Slatter and D. Krichevsky, editors]. New York: Plenum Press.
12. Bolli, R. (1991). Oxygen-derived free radicals and myocardial reperfusion injury: an overview. Cardiovascular Drugs and Therapy 5, 249-268.
13. Bolli, R., Jeroudi, M. O. & Patel, B. S. (1989). Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion: Evidence that myocardial 'stunning' is a manifestation of reperfusion injury. Circulation Research 65, 607-622.
14. Bowry, V. W., Ingold, K. U. & Stocker, R. (1992). Vitamin E in human low-density lipoprotein: when and how this antioxidant becomes a pro-oxidant. Biochemical Journal 288, 341-344.
15. Burton, G. W. & Traber, M. G. (1990). Vitamin E: antioxidant activity, biokinetics and bioavailability. Annual Reviews of Nutrition 10, 357-382.
16. Caragay, A. B. (1992). Cancer-preventive foods and ingredients. Food Technology 3, 65-68.
17. Cochrane, C. G. (1991). Cellular injury by oxidants. American Journal of Medicine 91, Suppl. 3C, 23S-30S.
18. Cohen, C. (1988). Oxygen radicals and Parkinson's disease. In Oxygen Radicals and Tissue Injury Symposium (Proceedings), pp. 130-135 [B. Halliwell, editor]. Bethesda: Federation of American Societies for Experimental Biology.
19. Cook, R. (1994). Fatal Cure. New York: Berkley Publishing Group.
20. Desai, T. K., Maliakkal, J., Kinzie, J. L., Ehrinpreis, M. N., Luk, G. D. & Ceijka, J. (1992). Taurine deficiency after intensive chemotherapy and/or radiation. American Journal of Clinical Nutrition 55, 708-711.
21. Dilley, J. V. (1972). The origin of urinary taurine excretion during chronic radiation injury. Radiation Research 50, 191-196.
22. Diplock, A. T. (1991). Antioxidant nutrients and disease prevention. An overview. American Journal of Clinical Nutrition 53, 189S-193S
23. Diplock, A. T. (1994). Antioxidants and disease prevention. Molecular Aspects of Medicine 15, 293-376.
24. Doba, T., Burton, G. W. & Ingold, K. U. (1985). The effect of vitamin C either alone or in the presence of vitamin E or a water soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes. Biochimica et Biophysica Acta 835, 298-303.
25. Dressel, K., Stehle, P. & Fürst, P. (1994). Novel taurine-containing substrates for clinical nutrition - in vitro evidence of hydrolysis. Clinical Nutrition 13, Suppl. 1, 21 Abstr.
26. Dröge, W. (1993). Cysteine and glutathione deficiency in AIDS patients. A rationale for treatment with N-acetyl cysteine. Pharmacology 46, 61-65.
27. Dröge, W., Eik, H. P. & Gminder, H. (1991). Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives. American Journal of Medicine 91, Suppl. 3C, 1405-1445.
28. Esterbauer, H., Zollern, H. & Schaur, R. J. (1988). Hydroxyalkenals: cytotoxic products of lipid peroxidation. ISI Atlas Science Biochemistry 1, 311-315.
29. Frei, B. (editor). (1994). Natural Antioxidants in Human Health and Disease. San Diego: Academic Press.
30. Fridovich, I. (1988). The biology of oxygen radicals: general concepts. In Oxygen Radicals and Tissue Injury Symposium (Proceedings), pp. 1-5 [B. Halliwell, editor]. Bethesda: Federation of American Societies for Experimental Biology.
31. Fürst, P. (1994). New parenteral substrates in clinical nutrition. Part I. Introduction. New substrates in protein nutrition. European Journal of Clinical Nutrition 48, 607-616.
32. Fürst, P., Bergström, J., Hellström, B. & Kinney, J. (1981). Amino acid metabolism in cancer. In Nutrition and Metabolism, pp. 75-89 [R. Kluthe and G. W. Löhr, editors]. Stuttgart and New York: Georg Thieme Verlag.
33. Fürst, P. & Stehle, P. (1994). Parenteral nutrition substrates. In Artificial Nutrition Support in Clinical Practice, pp. 301-322 [J. Payne-James, G. Grimble and D. Silk, editors]. London, Melbourne and Auckland: Arnold Publishers.
34. Gerlach, T., Biesalski, H. K., Weiser, H., Haeussermann, B. & Baessler, K. H. (1989). Vitamin A in parenteral nutrition: uptake and distribution of retinyl esters after intravenous application. American Journal of Clinical Nutrition 50, 1029-1038.
35. Gerschman, R. (1981). Historical introduction to the 'free radical theory' of oxygen toxicity. In Oxygen and Living Processes, an Interdisciplinary Approach, pp. 44-46 [D. L. Gilbert, editor]. New York: Springer Verlag.
36. Goode, H. F., Cowley, H. C. & Walker, B. E. (1995). Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction. Critical Care Medicine 23, 646-651.
37. Gordon, R. F. & Heller, R. F. (1992). Taurine protection of lungs in hamster models of oxidant injury. A morphologic time study of paraquat and bleomycin treatment. In Taurine: Nutritional Value and Mechanisms of Action, pp. 319-328 [J. B. Lombardini, S. W. Schaffer and J. Azuma, editors]. New York: Plenum Press.
38. Greenberg, E. R., Baron, J. A. & Stukel, T. A. (1994). A clinical trial of antioxidant vitamins to prevent colorectal adenoma. New England Journal of Medicine 331, 141-147.
39. Griffiths, R. D., Jones, C. & Palmer, T. E. A. (1996). Survival of intensive care patients given glutamine-supplemented parenteral nutrition: a double-blind, randomized treatment study. Proceedings of the Nutrition Society 55, 158A.
40. Grimble, R. F. (1994). Nutritional antioxidants and the modulation of inflammation: theory and practice. New Horizons 2, 175-180.
41. Halliwell, B. (1987). Oxidants and human disease: some new concepts. FASEB Journal 1, 358-364.
42. Halliwell, B. (1989). Superoxide, iron, vascular endothelium and reperfusion injury. Free Radical Research Communications 5, 315-318.
43. Halliwell, B. & Cross, C. E. (1991). Reactive oxygen species, antioxidants, and acquired immunodeficiency syndrome. Archives of Internal Medicine 151, 29-31.
44. Halliwell, B., Evans, P. J., Kaur, H. & Aruoma, O. I. (1994). Free radicals, tissue injury, and human disease. A potential for therapeutic use of antioxidants. In Organ Metabolism and Nutrition. Ideas for Future Critical Care, pp. 423-446 [J. M. Kinney and H. N. Tucker, editors]. New York: Raven Press Ltd.
45. Halliwell, B. & Gutteridge, J. M. C. (1989). Free Radicals in Biology and Medicine, 2nd ed. Oxford: Clarendon Press.
46. Halliwell, B. & Gutteridge, J. M. C. (1992). Biologically relevant metal ion-dependent hydroxyl radical generation - an update. FEBS Letters 307, 108-112.
47. Harbrecht, B. G., Billiar, T. R. & Stadler, J. (1992). Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury. Journal of Leukocyte Biology 52, 390-394.
48. Harward, T. R. S., Coe, D., Souba, W. W., Klingman, N. & Seeger, J. M. (1994). Glutamine preserves gut glutathione during intestinal ischemia/reperfusion. Journal of Surgical Research 56, 351-355.
49. Hogg, N., Darley-Usmar, V. M. & Wilson, M. T. (1992). Production of hydroxyl radicals from the simultaneous generation of Superoxide and nitric oxide. Biochemical Journal 281, 419-424.
50. Hong, R. W., Rounds, J. D., Helton, W. S., Robinson, M. K. & Wilmore, D. W. (1992). Glutamine preserves liver glutathione after lethal hepatic injury. Annals of Surgery 215, 114-119.
51. Hummel, M., Stehle, P. & Fürst, P. (1995). Intestinal uptake and utilization of vascular taurine-containing conjugates - a study in the isolated perfused small intestine of the rat. Clinical Nutrition 14, Suppl. 2, 21 Abstr.
52. Jeroudi, M. O., Triana, F. J. & Patel, B. (1990). Effect of Superoxide dismutase and catalase, given separately, on myocardial 'stunning'. American Journal of Physiology 259, H889-H901.
53. Kelly, F. J. (1994). Vitamin E supplementation in the critically ill patients. Too narrow a view? Nutrition in Clinical Practice 9, 141-145.
54. Krinsky, N. I. (1989). Antioxidant functions of carotenoids. Free Radicals in Biology and Medicine 7, 617-635.
55. Lövenberg, M. E., Todhunter, E. N., Wilson, E. D., Feeney, M. L. & Savage, J. R. (1968). Food and Man, p. 15. New York: John Wiley and Sons.
56. McCord, J. M. (1995). Superoxide radical: Controversies, contradictions and paradoxes. Proceedings of the Society for Experimental Biology and Medicine 209, 112-116.
57. McCord, J. M. & Fridovich, I. (1969). Superoxide dismutase. An enzymic function for erythrocuprein themocuprein. Journal of Biological Chemistry 224, 6049-6055.
58. Magnusson, I., Ekman, L. & Wangdahl, M. (1989). N-acetyl-L-tyrosine and N-acetyl-L-cysteine as tyrosine and cysteine precursors during intravenous infusion in humans. Metabolism 38, 957-961.
59. Meydani, S. K., Hayek, M. & Coleman, L. (1992). Influence of vitamins E and B on immune responses. Annals of the New York Academy of Sciences 669, 125-140.
60. Mihm, S. & Dröge, W. (1990). Intracellular glutathione level controls DNA binding activity of NFxB like proteins. Immunobiology 181, 245-247.
61. Mihm, S., Ennen, J. & Pessagra, U. (1991). Inhibition of HIV-1 replication and NFxB activity by cysteine and cysteine derivatives. AIDS 5, 497-503.
62. Murrell, G. A. C., Francis, M. J. O. & Bromley, L. (1989). Oxygen free radicals stimulate fibroblast proliferation. Biochemical Society Transactions 17, 484.
63. Myers, M. L., Bolli, R. & Lekich, R. F. (1985). Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional eschemia. Circulation 72, 915-921.
64. Myers, M. L., Bolli, R. & Lekich, R. F. (1986). N-2-mercaptopropionyl glycine improves recovery of myocardial function following reversible regional ischemia. Journal of the American College of Cardiology 8, 1161-1168.
65. National Academy of Sciences (1989). Diet and Health: Implications for Reducing Chronic Disease Risk. Washington, DC: National Academy of Sciences.
66. Nattakom, T. V., Charlton, A. & Wilmore, D. W. (1995). Use of vitamin E and glutamine in the successful treatment of severe veno-occlusive disease following bone marrow transplantation. Nutrition in Clinical Practice 10, 16-18.
67. Nava, E., Palmer, R. M. J. & Moncada, S. (1991). Inhibition of nitric oxide synthesis in septic shock - how much is beneficial? Lancet 338, 1555-1557.
68. Nelson, S. K., Bose, S. K. & McCord, J. M. (1994). The toxicity of high-dose Superoxide dismutase suggests that Superoxide can both initiate and terminate lipid peroxidation in the reperfused heart. Free Radicals in Biology and Medicine 16, 195-200.
69. Odelye, O. & Watson, R. R. (1991). The potential role of vitamin E in the treatment of immunologic abnormalities during acquired immune deficiency syndrome. Progress in Food and Nutrition Science 15, 1-19.
70. Ollenschläger, G., Jansen, S., Schindler, J., Rasokat, H., Schrappe-Bächer, M. & Roth, E. (1988). Plasma amino acid pattern of patients with HIV infection. Clinical Chemistry 34, 1787-1789.
71. Paauw, J. D. & Davis, A. T. (1990). Taurine concentration in serum of critically injured patients and age- and sex-matched control subjects. American Journal of Clinical Nutrition 52, 657-660.
72. Park, E., Quinn, M. R. & Wright, C. E. (1993). Taurine chloramine inhibits the synthesis of nitric oxide and the release of tumor necrosis factor in activated RAW 264.7 cells. Journal of Leukocyte Biology 54, 119-124.
73. Pathirana, C. & Grimble, R. F. (1992). Taurine and serine supplementation modulates the metabolic response to tumor necrosis factor α in rats fed a low protein diet. Journal of Nutrition 122, 1369-1375.
74. Pauling, L. (1970). Vitamin C and the Common Cold, p. 1. San Francisco: W. H. Freeman & Co.
75. Pratt, D. E. (1992). Natural antioxidants from plant material. In Phenolic Compounds in Food and Their Effects on Health, pp. 54-71 [M.-T. Huang, C.-T. Ho and C. Y. Lee, editors]. New York: American Chemical Society.
76. Pratt, D. E. & Hudson, B. I. F. (1990). Natural antioxidants not exploited commercially. In Food Antioxidants, pp. 171-191 [B. S. F. Hudson, editor]. London and New York: Elsevier Applied Science.
77. Radi, R., Beckman, J. S. & Bush, K. M. (1990). Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of Superoxide and nitric oxide. Journal of Biological Chemistry 266, 4244-4250.
78. Roederer, M., Elia, S. W. & Staal, F. J. T. (1992). N-acetyl-cysteine. A new approach to anti-HIV therapy. AIDS Research and Human Retroviruses 8, 209-217.
79. Rouse, K., Nwokedi, E., Woodliff, J. E., Epstein, J. & Klimberg, V. S. (1995). Glutamine enhances selectivity of chemotherapy through changes in glutathione metabolism. Annals of Surgery 221, 420-426.
80. Rynearson, E. H. (1974). Americans love hogwash. Nutritional Reviews 32, Suppl. 1, 1-14.
81. Schiller, H. J., Reilly, P. M. & Bulkley, G. B. (1993). Antioxidant therapy. Critical Care Medicine 21, Suppl., S92-S102.
82. Seeger, W., Ziegler, A. & Wolf, H. R. (1987). Serum alpha-tocopherol levels after high dose enterai vitamin E administration in patients with acute respiratory failure. Intensive Care Medicine 13, 395-400.
83. Steinmetz, K. A. & Potter, J. D. (1991). Vegetables, fruit and cancer. II Mechanisms. Cancer, Causes and Control 2, 427-442.
84. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group (1994). The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers. New England Journal of Medicine 330, 1029-1035.
85. Vinton, N. E., Laidlaw, S. A., Ament, M. E. & Kopple, J. D. (1987). Pediatric Research 21, 399-403.
86. Von Sonntag, C. (1987). The Chemical Basis of Radiation Biology. London: Taylor and Francis.
87. 2 or products of activated neutrophisis. American Journal of Medicine 91, Suppl. 3C, 89S-94S.
88. Weber, P., Bendich, A. & Schalch, W. (1996). Vitamin C and human health - a review of recent data relevant to human requirements. International Journal of Vitamin and Nutrition Research 66, 19-30.
89. Wolf, H. & Seeger, W. (1982). Experimental and clinical results in shock lung treatment with vitamin E. Advances of the New York Academy of Sciences 393, 392-398.
90. Youn, Y. K., Lalonde, C. & Demling, R. (1991). Use of antioxidant therapy in shock and trauma. Circulatory Shock 35, 245-249.