Clarithromycin pharmacokinetics after oral administration with or without fasting in crossbred beagles

Journal of Small Animal Practice

Volumn 37, Issue 11, 1996, Pages 535-539

  Vilmanyi E ^a   Kung K ^a   Riond, J L ^a   Trumpi B ^b   Wanner, M ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Abbott AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

ANTIINFECTIVE AGENT; CLARITHROMYCIN;

ANIMAL; ARTICLE; BLOOD; COMPARATIVE STUDY; DOG; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; RANDOMIZATION; SPECIES DIFFERENCE; TIME;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; CLARITHROMYCIN; DOGS; FEMALE; INJECTIONS, INTRAVENOUS; MALE; RANDOM ALLOCATION; SPECIES SPECIFICITY; TIME FACTORS;

EID: 0030279161     PISSN: 00224510     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-5827.1996.tb02314.x     Document Type: Article

References (22)

1. BAGGOT, J. D. (1984) Factors involved in the choice of routes of administration of antimicrobial drugs. Journal of the American Veterinary Medical Association 185, 1076-1082
2. BAHAL, N. & NAHATA, M. C. (1992) The new macrolide antibiotics: Azithromycin, clarithromycin, dirithromycin, and roxithromycin. Annals of Pharmacotherapy 26, 46-55
3. BOUTIN-PANNETIER, M. S., DELHOTAL-LANDES, B. & FLOUVAT, B. (1986) Influence de l'alimentation sur la biodisponihilité des médicaments. Thérapie 41, 397-402
4. CHU, S.-Y., PARK, Y., LOCKE, C., WILSON, D. S. & CAVANAUGH, J. G. (1992) Drug-food interaction potential of clarithromycin, a new macrolide antibiotic. Journal of Clinical Pharmacology 32, 32-36
5. CHU, S.-Y., SENNELLO, L. T. & SONDERS, R. G. (1991) Simultaneous determination of clarithromycin and 14(R)-hydroxyclarithromycin in plasma and urine using high-performance liquid chromatography with electrochemical detection. Journal of Chromatography 571, 199-208
6. GROSSE. R. & BURT D. G. (1984) Antibiotic concentration in the serum of dogs and cats following a single oral dose of cephalexin. Veterinary Record. 115, 106-107
7. ERIRSSON, A., RAURAAMA, V., HAPPONEN, I. & MERO, M. (1990) Feeding reduces the absorption of erythromycin in the dog. Acta Veterinaria Scandinavica 31, 497-499
8. FERNANDES, P. B., RAMER, N., RODE, R. A. & FREIBERG, L. (1988) Bioassay for A-56268 (TE-031) and identification of its major metabolite, 14-hydroxy-6-O-methyl erythromycin. European Journal of Clinical Microbiology and Infectious Diseases 7, 73-76
9. FRASCHINI, F., SCAGLIONE, F. & DEMARTINI, G. (1993) Clarithromycin clinical pharmacokinetics. Clinical Pharmacokinetics 25, 189-204
10. FREY, H.-H. & LöSCHER, W. (1985) Pharmacokinetics of antiepileptic drugs in the dog: a review. Journal of Veterinary Pharmacology and Therapeutics 8, 219-233
11. GOUYETTE, A. (1983) Pharmacokinetics: Statistical moment calculation. Drug Research 33, 173-176
12. HEINZEL, G. (1991) TopFit-Methoden-Handbuch, Version 1.1. Biberach an der Riss, Thomae, Germany, pp 1-59
13. KSHIRSAGAR, N. A. & ANKALASERIA. P. S. (1987) Effect of food on doxycycline absorption. Journal of Postgraduate Medicine 33, 117-119
14. KUNG, K., HAUSER, B. & WANNER, M. (1995) Effect of the interval between feeding and drug administration on oral ampicillin absorption in dogs. Journal of Small Animal Practice 36, 65-68
15. KÜNG, K. & WANNER, M. (1994) Bioavailability of different forms of amoxycillin administered orally to dogs. Veterinary Record 135, 552-554
16. MCGUIRE, J. M., BUNCH, R. L., ANDERSON, R. G., BOAZ, H. E., FLYNN, E. H., POWELL, H. M. & SMITH, J. W. (1952) 'Ilotycin', a new antibiotic. Antibiotics and Chemotherapy 2, 281-283
17. PETERS, D. H. & CLISSOLD, S. P. (1992) Clarithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential. Drugs 44, 117-164
18. PISCITELLI, S. C., DANZIGER, L. H. & RODVOLD, K. A. (1992) Clarithromycin and azithromycin: new macrolide antibiotics. Clinical Pharmacy 11, 137-152
19. POWERS, J. (1990) Statistical analysis of pharmacokinetic data. Journal of Veterinary Pharmacology and Therapeutics 13, 113-120
20. SHIMANO. K., KOMDO, O., MIWA, A., HIGASHI, Y., KOYAMA, I., YOSHIDA, T., ITO, Y., HIROSE, J. & GOTO, S. (1995) Evaluation of uniform-sized microcapsules using a vibration nozzle method. Drug Development and Industrial Pharmacy 21, 331-347
21. SUWA, T., YOSHIDA, H., YOSHITOMI, S. & KAMEL, K. (1986) Metabolism of TE-031 (A-56268), a new macrolide antibiotic, in rat, dog, monkey and man. 26th. Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans. Abstract 414
22. WHITMAN, M. S. & TUNKEL, A. R. (1992) Azithromycin and clarithromycin: Overview and comparison with erythromycin. Infection Control and Hospital Epidemiology 13, 357-368