Molecular and structural aspects of fimbriae biosynthesis and assembly in Escherichia coli

FEMS Microbiology Reviews

Volumn 19, Issue 1, 1996, Pages 25-52

  Mol, Olaf ^a   Oudega, Bauke ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Enterotoxigenic bacterium; Escherichia coli; Fimbriae biosynthesis; Outer membrane usher; Periplasmic molecular chaperone; Regulation

Indexed keywords

BIOSYNTHESIS; ESCHERICHIA COLI; FIMBRIA; GENE EXPRESSION REGULATION; MOLECULAR GENETICS; NONHUMAN; OPERON; OUTER MEMBRANE; PROTEIN ASSEMBLY; REVIEW;

BACTERIA (MICROORGANISMS); ESCHERICHIA; ESCHERICHIA COLI;

EID: 0030273775     PISSN: 01686445     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-6445(96)00022-8     Document Type: Review

References (239)

1. [1] Finlay, B.B. and Falkow, S. (1989) Common themes in microbial pathogenicity. Microbiol. Rev. 53, 210-230.
2. [2] Krogfelt, K.A. (1991) Bacterial adhesion: genetics, biogenesis, and role in pathogenesis of fimbrial adhesins of Escherichia coli. Rev. Infect. Dis. 13, 721-735.
3. [3] Duguid, J.P., Smith, I.W., Dempster G. and Edmunds, P.N. (1955) Non-flagellar filamentous appedages ('fimbriae') and haemagglutinating activity in Bacterium coli. J. Pathol. Bacteriol. 70, 335-348.
4. [4] Brinton, C.C. (1959) Non-flagellar appendages of bacteria. Nature 183, 782-786.
5. [5] Ottow, J.C.G. (1975) Ecology, physiology, and genetics of fimbriae and pili. Ann. Rev. Microbiol. 29, 79-108.
6. [6] Schmidt, M.A. (1994) Nonfimbrial adhesins of Escherichia coli. In: Fimbriae: Adhesion, Genetics, Biogenesis, and Vaccines (Klemm, P., Ed.), pp. 85-96. CRC Press, Boca Raton.
7. [7] Strom, M.S., Nunn, D.N. and Lory, S. (1994) Posttranslational processing of type IV prepilin and homologs by PilD of Pseudomonas aeruginosa. Meth. Enzym. 235, 527-540.
8. [8] Taniguchi, T., Fujino, Y., Yamamoto, K., Miwatani, T. and Honda, T. (1995) Sequencing of the gene encoding the major pilin of pilus colonization factor antigen III (CFA/III) of human enterotoxigenic Escherichia coli and evidence that CFA/III is related to type IV pili. Infect. Immun. 63, 724-728.
9. [9] Rudel, T., Scheuerpflug, I. and Meyer, T.F. (1995) Neisseria PilC protein identified as type-4 pilus tip-located adhesin. Nature 373, 357-359.
10. [10] Woods, D.E., Straus, D.C., Johanson, E.G., Berry, V.K. and Bass, J.A. (1980) Role of pili in adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells. Infect. Immun. 29, 1146-1151.
11. [11] Nassif, X., Beretti, J.-L., Lowy, J., Stenberg, P., O'Gaora, P., Pfeifer, J., Normark, S. and So, M. (1994) Poles of pilin and PilC in adhesion of Neisseria meningitidis to human epithelial and endothelial cells. Proc. Natl. Acad. Sci. USA 91, 3769-3773.
12. [12] Parge, H.E., Forest, K.T., Hickey, M.J., Christensen, D.A., Getzoff, E.D. and Tainer, J.A. (1995) Structure of the fibre-forming protein pilin at 2.6 Å resolution. Nature 378, 32-38.
13. [13] Duguid, J.P. and Old, D.C. (1980) Adhesive properties of Enterobacteriaceae (Beachey, E.H., Ed.) Chapman & Hall, London.
14. [14] Hacker, J. (1990) Genetic determinants coding for fimbriae and adhesisns of extraintertinal Escherichia coli. Curr. Topics Microbiol. Immunol. 151, 1-27.
15. [15] Klemm, P. and Krogfelt, K.A. (1994) Type 1 fimbriae of Escherichia coli. In: Fimbriae: Adhesion, Genetics, Biogenesis, and Vaccines (Klemm, P., Ed.), pp. 9-26. CRC Press, Boca Raton.
16. [16] Hull, S.A., Gill, R.E., Hsu, P., Minshew, B.H. and Falkow, S. (1981) Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect. Immun. 33, 933-938.
17. [17] Normark, S., Lark, D., Hull, R., Norgren, M., Båga, M., O'Hanley, P., Schoolnik, G. and Falkows, S. (1983) Genetics of digalactoside-binding adhesin from a uropathogenic Escherichia coli strain. Infect. Immun. 41, 942-949.
18. [18] Lund, B., Lindberg, F.P., Båga, M. and Normark, S. (1985) Globoside-specific adhesin of uropathogenic Escherichia coli are encoded by similar trans-complementable gene clusters. J. Bacteriol. 162, 1293-1301.
19. [19] De Graaf, F.K. and Gaastra, W. (1994) fimbriae of enterotoxigenic Escherichia coli. In: Fimbriae: Adhesion. Genetics, Biogenesis, and Vaccines (Klemm, P., Ed.), pp. 53-83. CRC Press, Boca Raton.
20. [20] Sack. R.B. (1975) Human diarrheal disease caused by enterotoxigenic Escherichia coli. Ann. Rev. Microbiol. 29, 333-353.
21. [21] De Graaf, F.K. and Mooi, F.R. (1986) The fimbrial adhesins of Escherichia coli. Adv. Microbial. Physiol. 28, 65-143.
22. [22] Gong, M. and Makowski, L. (1992) Helical structure of P pili from Escherichia coli: evidence from X-ray diffraction and scanning transmission electron microscopy. J. Mol. Biol. 228, 735-742.
23. [23] Brinton, C.C. (1965) The structure, function, synthesis, and genetic control of bacterial pili and molecular model for DNA and RNA transport in gram-negative bacteria. Trans. NY Acad. Sci. 27, 1003-1054.
24. [24] Simons, B.L., Mol, O., Van Breemen, J.F.L. and Oudega, B. (1994) Morphological appearances of K88ab fimbriae and optical diffraction analysis of K88 paracrystalline structures. FEMS Microbiol. Lett. 118, 83-88.
25. [25] Bullitt, E. and Makowski, L. (1995) Structural polymorphism of bacterial adhesion pili. Nature 373, 164-167.
26. [26] Abraham, S.N., Land, M., Ponniah, S., Endres, R., Hasty, D.L. and Babu, J.P. (1992) Glycerol-induced unraveling of the tight helical conformation of Escherichia coli type 1 fimbriae. J. Bacteriol. 174, 5145-5148.
27. [27] Isaacson, R.E. and Richter, P. (1981) Escherichia coli 987P pilus: purification and partial characterization. J. Bacteriol. 146, 784-789.
28. [28] Knutton, S., McConnell, M.M., Rowe, B. and McNeish, A.S. (1989) Adhesion and ultrastructural properties of human enterotoxigenic Escherichia coli producing colonization factor antigens III and IV. Infect. Immun. 57, 3364-3371.
29. [29] Ørskov, I., Ørskov, F., Jann, B. and Jann, K. (1977) Serology, chemistry and genetics of Escherichia coli. Bacteriol. Rev. 41, 667-710.
30. [30] Inoue, O.J., Lee, J.H. and Isaacson, R.E. (1993) Transcriptional organization of the Escherichia coli pilus adhesin K99. Mol. Microbiol. 10, 607-613.
31. [31] Kusters, J.G. and Gaastra, W. (1994) Fimbrial operons and evolution. In: Fimbriae: Adhesion, Genetics, Biogenesis, and Vaccines (Klemm, P., Ed.), pp. 179-196. CRC Press, Boca Raton.
32. [32] Ørskov, I., Ørskov, F., Sojka, W.J. and Leach, J.M. (1961) Simultaneous occurrence of Escherichia coli B and L antigens in strains from diseased swine. Acta Pathol. Microbiol. Scand. 53, 404-422.
33. [33] Willemsen, P.T.J. and De Graaf, F.K. (1992) Age and serotype dependent binding of K88 fimbriae to porcine intestinal receptors. Microb. Pathog. 12, 367-375.
34. [34] Wilson, M.R. and Hohmann, A.W. (1976) Immunity to Escherichia coli in pigs: adhesion of enteropathogenic Escherichia coli to isolated intestinal epithelial cells. Infect. Immun. 10, 776-782.
35. [35] Jones, G.W. and Rutter, J.M. (1972) Role of K88 antigen in the pathogenesis of neonatal diarrhea caused by Escherichia coli in piglets. Infect. Immun. 6, 918-927.
36. [36] Anderson, M.J., Whitehead, J.S. and Kim, Y.S. (1980) Interaction of Escherichia coli K88 antigen with porcine intestinal epithelial brush border membranes. Infect. Immun. 29, 897-901.
37. [37] Sellwood, R. (1980) The interaction of the k88 antigen with porcine intestinal epithelial cell brush border. Biochim. Biophys. Acta 632, 326-335.
38. [38] Ørskov, I., Ørskov. F, Sojka, W.J. and Witting, W. (1964) K antigens K88ab (L) and K88ac (L) in Escherichia coli. Acta Pathol. Microbiol. Scand. Sect. B 62, 439-447.
39. [39] Guinée, P.A.M. and Jansen, W.H. (1979) Behaviour of Escherichia coli K antigenes K88ab, K88ac and K88ad in immunoelectrophoresis, double diffusion and hemagglutination. Infect. Immun. 23, 700-705.
40. [40] Bakker, D. (1991) Studies on the K88 fimbriae of enteropathogenic Escherichia coli. Thesis, Vrije Universiteit Amsterdam, The Netherlands.
41. [41] Josephsen, J., Hansen, F., De Graaf, F.K. and Gaastra, W. (1984) The nucleotide sequence of the protein of the K88ac fimbriae of porcine enterotoxigenic Escherichia coli. FEMS Microbiol. Lett. 25, 301-306.
42. [42] Bakker, D., Willemsen, P.T.J., Simons, L.H., Van Zijderveld, F.G. and De Graaf, F.K. (1992) Characterization of the antigenic and adhesive properties of FaeG, the major subunit of K88 fimbriae. Mol. Microbiol. 6, 247-255.
43. [43] Bijlsma, I.G.W., De Nijs, A., Van der Meer, C. and Frink, J.F. (1982) Different pig phenotypes affecting adherence of Escherichia coli to jejunal brushborders by K88ab, K88ac or K88ad antigen. Infect. Immun. 37, 891-894.
44. [44] Virkola, R., Westerlund, B., Holthöfer, H., Parkkinen, J., Kekomäki, M. and Korhonen, T.K. (1988) Binding characteristics of Escherichia coli adhesis in human urinary bladder. Infect. Immun. 56, 2615-2622.
45. [45] Shipley, P.L., Gyles, C.L. and Falkow, S. (1978) Characterization of plasmids that encode for the K88 colonization factor. Infect. Immun. 20, 559-566.
46. [46] Bakker, D., Willemsen, P.T.J., Willems, R.H., Huisman, T.T., Mooi, F.R., Oudega, B., Stegehuis, F. and De Graaf, F.K. (1992) Identification of minor fimbrial subunits involved in biosynthesis of K88 fimbriae. J. Bacteriol. 174, 6350-6358.
47. [47] Mooi, F.R., De Graaf, F.K. and Van Embden, J.D.A. (1979) Cloning, mapping and expression of the genetic determinant that encodes for the K88ab antigen. Nucleic Acids Res. 6, 849-855.
48. [48] Huisman, T.T., Bakker, D., Klaasen, P. and De Graaf, F.K. (1994) Leucine-responsive regulatory protein, IS/ insertion, and the negative regulator FaeA control the expression of the fae (K88) operon in Escherichia coli. Mol. Microbiol. 11, 525-536.
49. [49] Bakker, D., Vader, C.H.M., Roosendaal, B., Mooi, F.R., Oudega, B. and De Giaal, F.K. (1991) Structure and function of periplasmic chaperone-like proteins involved in the biosynthesis of K88 and K99 fimbriae in enterotoxigenic Escherichia coli. Mol. Microbiol. 5, 875-886.
50. [50] Gaastra, W., Mooi, F.R., Stuijtje, A.R. and De Graaf, F.K. (1981) The nucleotide sequence of the gene encoding the K88ab protein subunit of porcine enterotoxigenic Escherichia coli. FEMS Microbiol. Let. 12, 41-46.
51. [51] Mooi, F.R., Harms, N., Bakker, D. and De Graaf, F.K. (1981) Organization and expression of genes involved in the production of the K88ab antigen. Infect. Immun. 32, 1155-1163.
52. [52] Mooi, F.R., Van Buuren, M., Koopman, G., Roosendaal, B. and De Graaf, F.K. (1984) K88ab gene of Escherichia coli encodes a fimbria-like protein distinct from the K88ab fimbrial adhesin. J. Bacteriol. 159, 482-487.
53. [53] Mooi, F.R., Claassen, I., Bakker, D., Kuipers, H. and De Graaf, F.K. (1986) Regulation and structure of an Escherichia coli gene coding for an outer membrane protein involved in export of K88ab fimbrial subunits. Nucl. Acids Res. 6, 2443-2457.
54. [54] Mooi, F.R., Wouters, C., Wijfjes, A. and De Graaf, F.K. (1982) Construction and characterization of mutants impaired in the biosynthesis of the K88ab antigen. J. Bacteriol. 150, 512-521.
55. [55] Jacobs, A.A.C., Roosendaal, B., Van Breemen, J.F.L. and De Graaf, F.K. (1987) Role of the phenylalanine-150 in the receptor-binding domain of the K88 fibrillar subunit. J. Bacteriol. 169, 4906-4911.
56. [56] Gaastra, W. and De Graaf, F.K. (1982) Host-specific fimbrial adhesins of non invasive enterotoxigenic Escherichia coli. Microbiol. Rev. 46, 129-161.
57. [57] Van Embden, J.D.A., De Graaf, F.K., Schoul, L.M. and Teppema, J.S. (1980) Cloning and expression of a deoxyribonucleic acid fragment that encodes for the adhesive antigen K99. Infect. Immun. 29, 1123-1133.
58. [58] Roosendaal, B. and De Graaf, F.K. (1989) The nucleotide sequence of the fanD gene encoding the large outer membrane protein involved in the biosynthesis of K99 fimbriae. Nucl. Acids Res. 17, 1263.
59. [59] Roosendaal, B., Gaastra, W. and De Graaf, F.K. (1984) The nuclcotide sequence of the gene encoding the K99 subunit of enterotoxigenic Escherichia coli. FEMS Microbiol. Lett. 22, 253-258.
60. [60] Simons, B.L., Willemsen, P.T.J., Bakker, D., Roosendaal, B., De Graaf, F.K. and Oudega, B. (1990) Structure, localization and function of FanF. a minor component of K99 fibrillae of enterotoxigenic Escherichia coli. Mol. Microbiol. 4, 2041-2050.
61. [61] Roosendaal, E., Boots, M. and De Graaf, F.K. (1987) Two novel genes, fanA and fanB involved in the biogenesis of K99 fimbriae. Nucl. Acids Res. 15, 5973-5984.
62. [62] Roosendaal, E., Damoiseaux, J., Jordi, W. and De Graaf, F.K. (1989) Transcriptional organization of the DNA region controlling expression of the K99 gene cluster. Mol. Gen. Genet. 215, 250-256.
63. [63] Roosendaal, E., Jacobs, A.A.C., Rathman, P., Sondermayer, C., Stegehuis, F., Oudega, B. and De Graaf, F.K. (1987) Primary structure and subcellular localization of two fimbrial subunit-like proteins involved in the biosynthesis of K99 fibrillae. Mol. Microbiol. 1, 211-217.
64. [64] Simons, L.H., Willemsen, P.T.J., Bakker, D., De Graaf, F.K. and Oudega, B. (1991) Localization and function of FanH and FanG, minor components of K99 fimbriae of enterotoxigenic Escherichia coli. Microb. Pathog. 11, 325-336.
65. [65] Smit, H., Gaastra, W., Kamerling, J.P., Vliegenthart, J.F.G. and De Graaf, F.K. (1984) Isolation and structural characterization of the equine erythrocyte receptor for enterotoxigenic Escherichia coli K99 fimbrial adhesin. Infect. Immun. 46, 578-584.
66. [66] Teneberg, S., Willemsen, P.T.J., De Graaf, F.K. and Karlsson, K.A. (1990) Receptor-active glycolipids of epithelial cells of the small intestine of young and adult pigs in relation to susceptibility to infection with Escherichia coli K99. FEBS Lett. 263, 10-14.
67. [67] Jacobs, A.A.C., Simons, E.H. and De Graaf, F.K. (1987) The role of lysine-132 and arginine-136 in the receptor-binding domain of the K99 fibrillar subunit. EMBO J. 6, 1805-1808.
68. [68] Ike, K., Nakazawa, M., Tsuchimolo, M., Ide, S. and Kashiwazaki, M. (1987) Hemagglutination of pilus antigen 987P of enterotoxigenic Escherichia coli. Microbiol. Immunol. 31, 1255-1258.
69. [69] Dean, E.A. and Isaacson, R.E. (1985) Location and distribution of a receptor for the 987P pilus of Escherichia coli in small intestines. Infect. Immun. 47, 345-348.
70. [70] Dean, E.A. and Isaacson, R.E. (1985) Purification and characterization of a receptor for the 987P pilus of Escherichia coli. Infect. Immun. 47, 98-105.
71. [71] Schifferli, D.M., Beachey, E.H. and Taylor, R.K. (1990) The 987P fimbrial gene cluster of enterotoxigenic Escherichia coli is plasmid encoded. Infect. Immun. 58, 149-156.
72. [72] Schifferli, D.M., Beachey, E.H. and Taylor, R.K. (1991) Genetic analysis of 987P adhesion and fimbriation of Escherichia coli: the fas genes link both phenotypes. J. Bacteriol. 173, 1230-1240.
73. [73] Ponniah, S., Endres, R.O., Hasty, D.L. and Abraham, S.N. (1991) Fragmentation of Escherichia coli type 1 fimbriae exposes cryptic D-mannose-binding sites. J. Bacteriol. 173, 4195-4202.
74. [74] Krogfelt, K.A., Bergmans, H. and Klemm, P. (1990) Direct evidence that the FimH protein is the mannose-specific adhesin of Escherichia coli type 1 fimbriae. Infect. Immun. 58, 1995-1998.
75. [75] Hanson, M.S. and Brinton, J.C.C. (1988) Identification and characterization of Escherichia coli type 1 pilus tip adhesion protein. Nature 332, 265-268.
76. [76] Fader, R.C. and Davis, P.C. (1980) Effect of piliation on Klebsiella pneumoniae infection in rat bladders. Infect. Immun. 30, 554.
77. [77] Duguid, J.P., Dakekar, M.R. and Wheater, D.W.F. (1976) Fimbriae and infectivity in Salmonella typhimurium. J. Med. Microbiol. 9, 459-473.
78. [78] Iwahi, J.T., Abe, Y., Nakao, M., Imade, A. and Tsuchiya, K. (1983) Role of type 1 fimbriae in the pathogenesis of ascending urinary tract infection induced by Escherichia coli in mice. Infect. Immun. 39, 1307-1315.
79. [79] Keith, B.R., Maurer, L., Spears, P.A. and Orndorff, P.E. (1986) Receptor-binding function of type 1 pili effects bladder colonization by a clinical isolate of Escherichia coli. Infect. Immun. 53, 693-696.
80. [80] Nakazawa, M., Haritami, M., Sugimoto, C. and Kashiwazaki, M. (1986) Colonization of enterotoxigenic Escherichia coli exhibiting mannose-sensitive hemagglutination to the small intestine of piglets. Microbiol. Immunol. 30, 485-489.
81. [81] Silverblatt, F.J. and Ofek, J. (1978) Influence of pili on the virulence of Proteus mirabilis in experimental haematogenous pyelonephritis. J. Infect. Dis. 138, 664-667.
82. [82] Bar-Shavit, Z., Goldman, R., Ofek, I., Sharon, N. and Mirelman, D. (1980) Mannose binding activity of Escherichia coli: a determinant of attachment and interaction of bacteria by macrophages. Infect. Immun. 29, 417-424.
83. [83] Blumenstock, E. and Jann, K. (1982) Adhesion of piliated Escherichia coli strains to phagocytes: differences between bacteria with mannose-sensitive pili and those with mannose-resistant pili. Infect. Immun. 35, 264-269.
84. [84] Sharon, N. (1987) Bacterial lectins, cell-cell recognition and infectious disease. FEBS Lett. 217, 145-157.
85. [85] Källenius, G., Möllby, R., Svensson, S.B., Helin, I., Hultberg, H., Cedergren, B. and Winberg, J. (1981) Occurrence of P-fimbriated Escherichia coli in urinary tract infections. Lancet ii, 1369-1372.
86. [86] Van Die, I., Van Geffen, B., Hoekstra, W. and Bergmans, H. (1985) Type IC fimbriae of an uropathogenic Escherichia coli strain: cloning and characterization of the genes involved in the expression of the 1C antigen and nucleotide sequence of the subunit gene. Gene 34, 187-196.
87. [87] Lund, B., Marklund, B.I., Strömberg, N., Lindberg, F., Karlsson, K.A. and Normark, S. (1988) Uropathogenic Escherichia coli can express serologically identical pili of different receptor binding specificities. Mol. Microbiol. 2, 255-263.
88. [88] Källenius, G., Möllby, R., Svensson, S.B., Winberg, J., Lundblad, A. and Svensson, S. (1980) The Pk antigen as a receptor for the hemagglutinin of pyelonephritic Escherichia coli. FEMS Microbiol. Lett. 7, 297-302.
89. [89] Strömberg, N., Nyholm, P.G., Pascher, I. and Normark, S. (1991) Saccharide orientation at the cell surface affects glycolipid receptor function. Proc. Natl. Acad. Sci. USA 88, 9340-9344.
90. [90] Strömberg, N., Marklund, B.-I., Lund, B., Iver, D., Hamers, A., Gaastra, W., Karlsson, K.-A. and Normark, S. (1990) Host-specificity of uropathogenic Escherichia coli depends on differences in binding specificity to Gala1-4Gal containing isoreceptors. EMBO J. 9, 2001-2010.
91. [91] Striker, R., Nilsson, U., Stonecipher, A., Magnusson, G. and Hultgren, S.J. (1995) Structural requirements for the glycolipid receptor of human uropathogenic Escherichia coli. Mol. Microbiol. 16, 1021-1029.
92. [92] Westerlund, B., Van Die, I., Kramer, C., Kuusela, P., Holthöfer, H., Tarkkanen, A.K., Virkola, R., Riegman, N., Hoekstra, W. and Korhonen, T.K. (1991) Multifunctional nature of P-fimbriae of uropathogenic Escherichia coli: mutations in fsoE and fsoF influence fimbrial binding to renal tubuli and immobilized fibronectin. Mol. Microbiol. 5, 2965-2975.
93. [93] Göransson, M. and Uhlin, B.E. (1984) Environmental temperature regulates transcription of a virulence pili operon in Escherichia coli. EMBO J. 3, 2885-2888.
94. [94] Jacobs, A.A.C. and De Graaf, F.K. (1985) Production of K88. K99 and F41 fibrillae in relation to growht phase and a rapid procedure for adhesin purification. FEMS Microbiol. Lett. 26, 15-19.
95. [95] Schmoll, T., Oudega, B. and Hacker, J. (1990) Use of a wild-type gene fusion to determine the influence of environmental conditions on expression of the S fimbrial adhesin in an Escherichia coli pathogen. J. Bacteriol. 172, 5103-5111.
96. [96] Van der Woude, M.W., De Graaf, F.K. and Van Verseveld, H.W. (1989) Production of the fimbrial adhesin 987P by enterotoxigenic Escherichia coli during growth under controlled conditions in a chemostat. J. Gen. Microbiol. 135, 3421-3429.
97. [97] Van der Woude, M.W., Braster, M., Van Verseveld, H.W. and De Graaf, F.K. (1990) Control of temperature-dependent synthesis of K99 fimbriae. FEMS Microbiol. Lett. 68, 183-188.
98. [98] White-Ziegler, C.A., Blyn, L.B., Braaten, B.A. and Low, D.A. (1990) Identification of an Escherichia coli genetic locus involved in thermoregulation of the pap operon. J. Bacteriol. 172, 1775-1782.
99. [99] White-Ziegler, C.A. and Low, D.A. (1992) Thermoregulation of the pap operon: Evidence for the involvement of RimJ. the N-terminal acetylase of ribosomal protein S5. J. Bacteriol. 174, 7003-7012.
100. [100] Van Verseveld, H.W., Bakker, P., van der Woude, T., Terleth, C. and De Graaf, F.K. (1985) Production of fimbrial adhesins K99 and F41 by enterotoxigenic Escherichia coli as a function of growth-rate domain. Infect. Immun. 49, 159-163.
101. [101] Mooi, F.R. and De Graaf, F.K. (1985) Molecular biology of fimbriae of enterotoxigenic Escherichia coli. Curr. Top. Microbiol. Immunol. 118, 119-138.
102. [102] Newman, E.B., D'ari, R. and Lin, R.T. (1992) The leucine-Lrp regulon in E.coli: A global response in search of a raison d'être. Cell 68, 617-619.
103. [103] Braaten, B.A., Blyn, L.B., Skinner, B.S. and Low, D.A. (1991) Evidence for a methylation-blocking factor (mbf) locus involved in pap pilus expression and phase variation in Escherichia coli. J. Bacteriol. 173, 1789-1800.
104. [104] Braaten, B.A., Platko, J.V., van der Woude, M., Simons, B., de Graaf, F.K., Calvo, J.M. and Low, D.A. (1992) Leucine-responsive regulatory protein controls the expression of both the pap and fan pili operons in Escherichia coli. Proc. Natl. Acad. Sci. USA 89, 4250-4254.
105. [105] Dorman, C.J. and Higgins, C.F. (1987) Fimbrial phase variation in Escherichia coli: dependence on integration host factor and homologies with other site-specific recombinases. J. Bacteriol. 169, 3840-3843.
106. [106] Eisenstein, B.I., Sweet, D.S., Vaughn, V. and Friedmann, D.I. (1987) Integration host factor IHF is required for the DNA inversion controlling phase variation in Escherichia coli. Proc. Natl. Acad. Sci. USA 84, 6506-6510.
107. [107] Båga, M., Göransson, M., Normark, S. and Uhlin, B.E. (1985) Transcriptional activation of a pap pilus virulence operon from uropathogenic Escherichia coli. EMBO J. 4, 3887-3893.
108. [108] Göransson, M., Forsman, K., Nilsson, P. and Uhlin, B.E. (1989) Upstream activating sequences that are shared by two divergently transcribed operons mediate cAMP-CRP regulation of pilus-adhesin in Escherichia coli. Mol. Microbiol. 3, 1557-1565.
109. [109] Jordi, B.J.A.M., Dagberg, B., De Haan, L.A.M., Hamers, A.M., Van der Zeijst, B.A.M., Gaastra, W. and Uhlin, B.E. (1992) The positive regulator CfaD overcomes the repression mediated by histone-like protein H-NS (H1) in the CFA/I fimbrial operon of Escherichia coli. EMBO J. 11, 2627-2632.
110. [110] Göransson, M., Sonden, B., Nilsson, P., Dagberg, B., Forsman, K., Emanuelsson, K. and Uhlin, B.E. (1990) Transcriptional silencing of the thermoregulation and gene expression in Escherichia coli. Nature 344, 682-685.
111. [111] Braaten, A.B., Nou, X., Kaltenbach, L.S. and Low, D.A. (1994) Methylation patterns in pap regulatory DNA control pyelonephritis-associated pili phase variation in Escherichia coli. Cell 76, 577-588.
112. [112] Blyn, L.B., Braaten, B.A. and Low, D.A. (1990) Regulation of pap pilin phase variation by a mechanism involving differential Dam methylation states. EMBO J. 9, 4045-4054.
113. [113] Klaasen, P. and De Graaf, F.K. (1990) Characterization of fapR, a positive regulator of expression of the 987P operon in enterotoxigenic Escherichia coli. Mol. Microbiol. 4, 1179-1783.
114. [114] Forsman, K., Göransson, M. and Uhlin, B.E. (1989) Autoregulation and multiple DNA interactions by a transcriptional regulatory protein in Escherichia coli pili biogenesis. EMBOJ. 8, 1271-1277.
115. [115] Nou, X., Skinner, B., Braaten, B.A., Blyn, L.B., Hirsch, D. and Low, D.A. (1993) Regulation of pyelonephritis-associated pili phase variation in Escherichia coli: binding of the PapI and the Lrp regulatory proteins is controlled by DNA methylation. Mol. Microbiol. 7, 545-553.
116. [116] Bilge, S.S., Apostol, J.M., Fullner, K.J. and Moseley, S.L. (1993) Transcriptional organization of the F1845 fimbrial adhesin determinant of Escherichia coli. Mol. Microbiol. 7, 993-1006.
117. [117] Morschhäuser, J., Uhlin, B.E. and Hacker, J. (1993) Transcriptional analysis and regulation of the sfa determinant coding for S fimbriae of pathogenic Escherichia coli strains. Mol. Gen. Genet. 238, 97-105.
118. [118] Van der Woude, M.W., Braaten, B.A. and Low, D.A. (1992) Evidence for global regulatory control of pilus expression in Escherichia coli by Lrp and DNA methylation: model building based on analysis of pap. Mol. Microbiol. 6, 2429-2435.
119. [119] Huisman, T.T. and De Graaf, F.K. (1995) Negative controle of fae (K88) expression by the 'global' regulator Lrp is modulated by the 'local' regulator FaeA and affected by DNA methylation. Mol. Microbiol. 16, 943-953.
120. [120] Abraham, J.M., Freitag, C.S., Clements, J.R. and Eisenstein, B.I. (1985) An invertible element of DNA controls phase variation of type 1 fimbriae of Escherichia coli. Proc. Natl. Acad. Sci. USA 82, 5724-5727.
121. [121] Klemm, P. (1986) Two regulatory fim genes, fimB and fimE, control the phase variation of type 1 fimbriae in Escherichia coli. EMBO J. 5, 1389-1393.
122. [122] McClain, M.S., Blomfield, I.C. and Eisenstein, B.I. (1991) Roles of fimB and fimE in site-specific DNA inversion associated with the phase variation of type 1 fimbriae in Escherichia coli. J. Bacteriol. 173, 5308-5314.
123. [123] Pallesen, L., Madsen, O. and Klemm, P. (1989) Regulation of the phase switch controlling expression of type 1 fimbriae in Escherichia coli. Mol. Microbiol. 3, 925-931.
124. [124] Båga, M., Norgren, M. and Normark, S. (1987) Biogenesis of E. coli Pap pili: PapH, a minor pilin subunit involved in cell anchoring and length modulation. Cell 49, 241-251.
125. [125] Hacker, J. and Morschhäuser, J. (1994) S and F1C Fimbriae. In: Fimbriae: Adhesion, Genetics, Biogenesis, and Vaccines (Klemm, P. Ed.), pp. 27-36. CRC Press, Boca Raton.
126. [126] Båga, M., Göransson, M., Normark, S. and Uhlin, B.E. (1988) Processed mRNA with differential stability in the regulation of E. coli pilin gene expression. Cell 52, 197-206.
127. [127] Bilge, S.S., Apostol, J.M., Aldape, M.A. and Moseley, S.L. (1993) mRNA processing independent of RNase III and RNase E in the expression of the 1845 fimbrial adhesin of Escherichia coli. Proc. Natl. Acad. Sci. USA 90, 1455-1459.
128. [128] Jordi, B.J.A.M., Op den Camp, I.E., De Haan, L.A.M., Van der Zeijst, B.A.M. and Gaastra, W. (1993) Differential decay of RNA of the CFA/I fimbrial operon and control of relative gene expression. J. Bacteriol. 175, 7976-7981.
129. [129] Dodd, D.C. and Eisenstein, B.J. (1984) Dependence of secretion and assembly of type 1 fimbrial subunits of Escherichia coli on normal protein export. J. Bacteriol. 159, 1077-1079.
130. [130] Wickner, W., Driessen, A.J.M. and Haiti, F.U. (1991) The enzymology of protein translocation across the Escherichia coli plasma membrane. Annu. Rev. Biochem. 60, 101-124.
131. [131] Pugsley, A.P. (1993) The complete general secretory pathway in Gram-negative bacteria. Microbiol. Rev. 57, 50-108.
132. [132] Lowe, M.A., Holt, S.C. and Eisenstein, B.I. (1987) Immunoelectron microscopic analysis of elongation of type 1 fimbriae in Escherichia coli. J. Bacteriol. 169, 157-163.
133. H + and ATP function at different steps af the catalytic cycle of preprotein translocation. Cell 64, 927-939.
134. [134] Lill, R., Cunningham, K., Brundage, L., Ito, K., Oliver, D. and Wickner, E. (1989) The SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of E. coli. EMBO J. 8, 961-966.
135. [135] Jacob-Dubuisson, F., Striker, R. and Hultgren, S.J. (1994) Chaperone-assisted self-assembly of pili independent of cellular energy. J. Biol. Chem. 269, 12447-12455.
136. [136] Oudega, B., De Graaf, M., De Boer, L., Bakker, D., Vader, C.E.M., Mooi, F.R. and De Graaf, F.K. (1989) Detection and identification of FaeC as a minor component of K88 fibrillae of Escherichia coli. Mol. Microbiol. 3, 645-652.
137. [137] Mooi, F.R., Wijfjes, A. and De Graaf, F.K. (1983) Identification and characterization of precursors in the biosynthesis of the K88ab fimbriae of Escherichia coli. J. Bacteriol. 154, 41-49.
138. [138] Kuehn, M.J., Heuser, J., Normark, S. and Hultgren, S.J. (1992) P pili in uropathogenic Escherichia coli are composite fibres with distinct fibrillar adhesive tips. Nature 356, 252-255.
139. [139] Lund, B., Lindberg, F., Marklund, B.I. and Normark, S. (1987) The PapG protein is the α-D-galactopyranosyl-(1-4)-β-D-galactopyranose-binding adhesin of uropathognic Escherichia coli. Proc. Natl. Acad. Sci. USA 84, 5898-5902.
140. [140] Jacob-Dubuisson, F., Heuser, J., Dodson, K., Normark, S. and Hultgren, S. (1993) Initiation of assembly and association of the structural elements of a bacterial pilus depend on two specialized tip proteins. EMBO J. 12, 837-847.
141. [141] Dodson, K.W., Dubuisson, F.J., Striker, R.T. and Hultgren, S.J. (1993) Outer-membrane PapC molecular usher discriminately recognizes periplasmic chaperone-pilus subunit complexes. Proc. Natl. Acad. Sci. USA 90, 3670-3674.
142. [142] Klemm, P. and Christiansen, G. (1987) Three fim genes required for the regulation of length and mediation of adhesin of Escherichia coli type 1 fimbriae. Mol. Gen. Genet. 208, 439-445.
143. [143] Klemm, P., Krogfelt, K.A., Hedegaard, L. and Christiansen, G. (1990) The major subunit of Escherichia coli type 1 fimbriae is not required for D-mannose-specific adhesion. Mol. Microbiol. 4, 553-559.
144. [144] Maurer, L. and Orndorff, P.E. (1987) Identification and characterization of genes determining receptor binding and pilus length of Escherichia coli type 1 pili. J. Bacteriol. 169, 640-645.
145. [145] Jones, C.H., Pinkner, J.S., Roth, R., Heuser, J., Nicholes, A.V., Abraham, S.N. and Hultgren, S.J. (1995) FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. Proc. Natl. Acad. Sci. USA 92, 2081-2085.
146. [146] Jordi, B.J.A.M., Willshaw, G.A., Van der Zeijst, B.A.M. and Gaastra, W. (1992) The complete nucleotide sequence of region 1 of the CFA/I fimbrial operon of human enterotoxigenic Escherichia coli. DNA Sequence 2, 257-263.
147. [147] Scott, J.R., Wakefield, J.C., Russell, P.W., Orndorff, P.E. and Froehlich, B.J. (1992) CooB is required for assembly but not transport of CS1 pilin. Mol. Microbiol. 6, 293-300.
148. [148] Perez-Casal, J., Swartley, J.S. and Scott, J.R. (1990) Gene encoding the major subunit of CS1 pili of human enterotoxigenic Escherichia coli. Infect. Immun. 58, 3594-3600.
149. [149] Jordi, B.J.A.M., Van Vliet, A.H.M., Willshaw, G.A., Van der Zeijst, B.A.M. and Gaastra, W. (1991) Analysis of the first two genes of the CS1 fimbrial operon in human enterotocigenic Escherichia coli of serotype O139:H28. FEMS Microbiol. Lett. 80, 265-270.
150. [150] Ellis, R.J. (1987) Proteins as molecular chaperones. Nature 328, 378-379.
151. [151] Gething, M.-J. and Sambrook, J. (1992) Protein folding in the cell. Nature 355, 33-45.
152. [152] Wülfing, C. and Plückthan, A. (1994) Protein folding in the periplasm of Escherichia coli. Mol. Microbiol. 12, 685-692.
153. [153] Bardwell, J.C., McGovern, K. and Beckwith, J. (1991) Identification of a protein required for disulfide bond formation in vivo. Cell 67, 581-589.
154. [154] Kamitani, S., Akiyama, Y. and Ito, K. (1992) Identification and characterization of an Escherichia coli gene required for the formation of correctly folded alkaline phosphatase, a periplasmic enzyme. EMBO J. 11, 57-62.
155. [155] Lui, J. and Walsh, C.T. (1990) Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: a periplasmic homolog of cyclophilin that is not inhibited by cyclosporine A. Proc. Natl. Acad. Sci. USA 87, 4028-4032.
156. [156] Hayano, T., Takahashi, N., Kato, S., Maki, N. and Suzuki, M. (1991) Two distinct forms of peptidylprolyl-cis-trans-isomerase are expressed separately in periplasmic and cytoplasmic compartments of Escherichia coli cells. Biochem. 30, 3041-3048.
157. [157] Kuehn, M.J., Haslam, D., Normark, S. and Hultgren, S.J. (1994) Structure, function, and biogenesis of Escherichia coli P pili. In: Fimbriae: Adhesion, Genetics, Biogenesis, and Vaccines (Klemm, P., Ed.), pp. 37-51. CRC Press, Boca Raton.
158. [158] Hultgren, S.J., Lindberg, F., Magnusson, G., Kihlberg, J., Tennent, J.M. and Normark, S. (1989) The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus. Proc. Natl. Acad. Sci. USA 86, 4357-4361.
159. [159] Kuehn, M.J., Normark, S. and Hultgren, S.J. (1991) Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits. Proc. Natl. Acad. Sci. USA 88, 10586-10590.
160. [160] Striker, R., Jacob-Dubuisson, D., Frieden, C. and Hultgren, S.J. (1994) Stable fiber-forming and nonfiber-forming chaperone-subunit complexes in pilus biogenesis. J. Biol. Chem. 269, 12233-12239.
161. [161] Holmgren, A. and Bränden, C.-I. (1989) Crystal structure of chaperone protein PapD reveals an immunoglobulin fold. Nature 342, 248-251.
162. [162] Holmgren, A., Keuhn, M.J., Bränden, C.-I. and Hultgren, S.J. (1992) Conserved immunoglobulin-like features in a family of periplasmic pilus chaperones in bacteria. EMBO J. 11, 1617-1622.
163. [163] Berlin, Y., Girardeau, J.P., Der Vartanian, M. and Martin, C. (1993) The ClpE protein involved in biogenesis of the CS31A capsule-like antigen is a member of a periplasmic chaperone family in gram-negative bacteria. FEMS Microbiol. Lett. 108, 59-68.
164. [164] Van Rosmalen, M. and Saier, M.H. (1993) Structure and evolutionary relationships between two families of bacterial extracytoplasmic chaperone proteins which function cooperatively in fimbrial assembly. Res. Microbiol. 144, 507-527.
165. [165] Iriarte, M., Vanooteghem, J.-C., Delor, I., Diaz, R., Knutton, S. and Cornells, G.R. (1993) The Myf fibrillae of Yersiniae enterocolitica. Mol. Microbiol. 9, 507-520.
166. [166] Jacob-Dubuisson, F., Kuehn, M. and Hultgren, S.J. (1993) A novel secretion apparatus for the assembly of adhesive bacterial pili. Trends Microbiol. 1, 50-55.
167. [167] Slonim, L.N., Pinkner, J.S., Bränden, C.-I. and Hultgren, S.J. (1992) Interactive surface in the PapD chaperone cleft is conserved in pilus chaperone superfamily and essential in subunit recognition and assembly. EMBO J. 11, 4747-4756.
168. [168] Kuehn, M.J., Ogg, D.J., Kihlberg, J., Slomm, L.N., Flemmer, K., Bergfors, T. and Hultgren, S.J. (1993) Structural basis of pilus subunit recognition by the PapD chaperone. Science 262, 1234-1241.
169. [169] Simons, B.L., Rathman, R., Malij, C.R., Oudega, B. and De Graaf, F.K. (1990) The penultimate tyrosine residue of the K99 fibrillar subunit is essential for stability of the protein and its interaction with the periplasmic carrier protein. FEMS Microbiol. Lett. 67, 107-112.
170. [170] Xu, Z., Jones, C.H., Haslam, D., Pinkner, J.S., Dodson, K., Kihlberg, J. and Hultgren, S.J. (1995) Molecular dissection of PapD interaction with PapG reveals two chaperone-binding sites. Mol. Microbiol. 16, 1011-1020.
171. [171] Kuehn, M.J., Dubuisson, F.J., Dodson, K.W., Slonim, L.N., Striker, R.T. and Hultgren, S.J. (1994) Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria. Meth. Enzym. 236, 282-306.
172. [172] Schifferli, D.M. and Alrutz, M.A. (1994) Permissive linker insertion sites in the outer membrane protein of 987P fimbriae of Escherichia coli. J. Bacteriol. 176, 1099-1110.
173. [173] Norgren, M., Båga, M,. Tennent, J.M. and Normark, S. (1987) Nucleotide sequence, regulation and functional analysis of the papC gene required for cell surface localization of Pap pili of uropathogenic Escherichia coli. Mol. Microbiol. 1, 169-178.
174. [174] Klemm, P. and Christiansen, G. (1990) The fimD gene required for cell surface localization of Escherichia coli type 1 fimbriae. Mol. Gen. Genet. 220, 334-338.
175. [175] Valent, Q.A., Zaal, J., De Graaf, F.K. and Oudega, B. (1995) Subcellular localization and topology of the K88 usher FaeD in Escherichia coli. Mol. Microbiol. 16, 1243-1257.
176. [176] Jones, C.H., Pinkner, J.S., Nicholes, A.V., Slonitn, L.N., Abraham, S.N. and Hultgren, S.J. (1993) FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria. Proc. Natl. Acad. Sci. USA 90, 8397-8401.
177. [177] Korth, M.J., Apostol, J., J.M., and Moseley, S.L. (1992) Functional expression of heterologous fimbrial subunits mediated by the F41, K88, and CS31A determinants of Escherichia coli. Infect. Immun. 60, 2500-2505.
178. [178] Klemm, P., Christiansen, G., Kreft, B., Marre, R. and Bergmans, H. (1994) Reciprocal exchange of minor components of type 1 and F1C fimbriae results in hybrid organelles with changed receptor specificities. J. Bacteriol. 176, 2227-2234.
179. [179] Klemm, P., Kreft, B., Jørgensen, B.J. and Christiansen, G. (1995) The export systems of type 1 and F1C fimbriae are interchangeable but work in parental pairs. J. Bacteriol. 177, 621-627.
180. [180] Klemm, P. (1984) The fimA gene encoding the type 1 fimbrial subunit of Escherichia coli: nucleotide sequence and primary structure of the protein. Eur. J. Biochem. 143, 395-399.
181. [181] Båga, M., Normark, S., Hardy, J., O'Hanley, P., Lark, D., Olsson, O., Schoolnik, G. and Falkow, S. (1984) Nucleotide sequence of the gene encoding the papA pilus subunit of human uropathogenic Escherichia coli. J. Bacteriol. 157, 330.
182. [182] Lindberg, F., Tennent, J.M., Hultgren, S.J., Lund, B. and Normark, S. (1989) PapD, a periplasmic transport protein in P-pilus biogenesis. J. Bacteriol. 171, 6052-6058.
183. [183] Mol, O., Visschers, R.W., De Graaf, F.K. and Oudega, B. (1994) Escherichia coli periplasmic chaperone FaeE is a homodimer and the chaperone-K88 subunit complex is a heterotrimer. Mol. Microbiol. 11, 391-402.
184. [184] Ørskov, I. and Ørskov, F. (1966) Episome-carried surface antigen K88 of Escherichia coli. I. Transmission of the determinant of the K88 antigen and influence of the transfer of chromosomal markers. J. Bacteriol. 91, 69-75.
185. [185] Shipley, P.L., Dougan, G. and Falkow, S. (1981) Identification and cloning of the genetic determinant that encodes for the K88ac adherence antigen. J. Bacteriol. 145, 920-925.
186. [186] De Graaf, F.K., Klemm, P. and Gaastra, W. (1980) Purification, characterization and partial covalent structure of Escherichia coli adhesive antigen K99. Infect. Immun. 33, 877-883.
187. [187] Ono, E., Abe, K., Nakazawa, M. and Naiki, M. (1989) Ganglioside epitope recognized by K99 from enterotoxigenic Escherichia coli. Infect. Immun. 57, 907-911.
188. [188] Moseley, S.L., Dougan, G., Schneider, R.A. and Moon, H.W. (1986) Cloning of chromosomal DNA encoding the F41 adhesin of enterotoxigenic Echerichia coli and genetic homology between adhesins F41 and K88. J. Bacteriol. 167, 799-804.
189. [189] De Graaf, F.K. and Roorda, I. (1982) Production, purification and characterization of the fimbrial adhesive antigen F41 isolated from calf enteropathogenic Escherichia coli strain B41M. Infect. Immun. 36, 751-758.
190. [190] Morris, J.A., Thorns, C.J., Wells, G.A., Scott, A.C. and Soika, W.J. (1983) The production of F41 fimbriae by piglet strains of enterotoxigenic Escherichia coli that lack K88, K99 and 987P fimbriae. J. Gen. Microbiol. 129, 2753-2759.
191. [191] Anderson, D.G. and Moseley, S.K. (1988) The Escherichia coli F41 adhesin: genetic organization, nucleotide sequence, and homology with the K88 determinant. J. Bacteriol. 170, 4890-4896.
192. [192] Mouricout, M.A. and Julien, R.A. (1987) Pilus-mediated binding of bovine enterotoxigenic Escherichia coli to calf small intestinal mucus. Infect. Immun. 55, 1216-1223.
193. [193] Lindahl, M. and Wadstöm, T. (1986) Binding to erythrocyte membrane glycoproteins and carbohydrate specificity of F41 fimbriae of enterotoxigenic Escherichia coli. FEMS Microbiol. Lett. 34, 297-300.
194. [194] Girardeau, J.P., Bertin, Y., Martin, C., Der Vartanian, M. and Boeuf, C. (1991) Sequence analysis of the clpG gene, which codes for the surface antigene CS31A subunit: evidence of an evolutionary relationship between CS31A, K88, and F41 subunit genes. J. Bacteriol. 173, 7673-7683.
195. [195] Girardeau, J.P., Der Vartanian, M., Ollier, J.L. and Contrepois, M. (1988) CS31A, a new K88-related fimbrial antigen on bovine enterotoxigenic and septicemic Escherichia coli strains. Infect. Immun. 56, 2180-2188.
196. [196] Contrepois, M., Dubourguier, H.C., Parodi, A.L., Girardeau, J.P. and Ollier, J.L. (1986) Septicemic Escherichia coli and experimental infection of calves. Vet. Microbiol. 12, 109-118.
197. [197] De Graaf, F.K. and Klaasen, P. (1987) Nucleotide sequence of the gene encoding the 987P fimbrial subunit of Escherichia coli. FEMS Microbiol. Lett. 42, 253-258.
198. [198] Lintermans, P., Polh, P., Deboeck, F., Bertels, A., Schlicker, C., Vanderkerckhove, J., Van Damme, J., Van Montagnu, M. and De Greve, H. (1988) Isolation and nucleotide sequence of the F17-A gene encoding the structural protein of the F17 fimbriae in bovine enterotoxigenic Escherichia coli. Infect. Immun. 56, 1475-1484.
199. [199] Lintermans, P.P., Polh, P., Bertels, A., Charlier, G., Vanderkerckhove, J., Van Damme, J., Schoup, J., Schlicker, C., Korhonen, T., De Greve, H. and Van Montagnu, M. (1988) Characterization and purification of the F17 adhesin on the surface of bovine enteropathogenic and septicemic Escherichia coli. Am. J. Vet. Res. 49, 1794-1799.
200. [200] Lintermans, P., Bertels, A., Schlicker, C., Deboeck, F., Harlier, Polh, P., Norgren, M., Normark, S., Van Montagnu, M. and De Greve, H. (1991) Identification, characterization and sequence of the F17-G gene, which determines receptor binding of Escherichia coli F17 fimbriae. J. Bacteriol. 173, 3366-3373.
201. [201] Evans, D.G., Silver, R.P., Evans, J., D.J., Chase, D.G. and Gorbach, S.L. (1975) Plasmid controlled colonization factor associated with virulence in Escherichia coli enterotoxigenic for humans. Infect. Immun. 12, 656-667.
202. [202] Pieroni, P., Worobec, E.A., Paranchych, W. and Amstrong, G.D. (1988) Identification of a human erythrocyte receptor for colonization factor antigen I pili expressed by H10407 enterotoxigenic Escherichia coli. Infect. Immun. 56, 1334-1340.
203. [203] Orø, H.S., Kolstoø, A.-B., Wennerås, C. and Svennerholm, A.-M. (1990) Identification of asialo GM1 as a binding structure for Escherichia coli colonization factor antigens. FEMS Microbiol. Lett. 72, 289-292.
204. [204] Wennerås, C.J., Holmgren, J. and Svannerholm, A.-M. (1990) The binding of colonization factor antigens to intestinal cell membrane proteins. FEMS Microbiol. Lett. 66, 107-112.
205. [205] Evans, D.G. and Evans, J.D.J. (1978) New surface associated heat-labile colonization factor antigen (CFA/II) produced by enterotoxigenic Escherichia coli of serogroups O6 and O8. Infect. Immun. 21, 638-647.
206. [206] Smyth, C.J. (1982) Two mannose-resistant haemagglutinins on enterotoxigenic Escherichia coli of serotype O6:K15:H16 or H-isolated from travelers' and infantile diarrhoea. J. Gen. Microbiol. 128, 2081-2096.
207. [207] Cravioto, A., Scotland, S.M. and Rowe, B. (1982) Hemagglutination activity and colonization factor antigens I and II in enterotoxigenic and non-enterotoxigenic strains of Escherichia coli isolated from humans. Infect. Immun. 36, 189-197.
208. [208] Sjöberg, P.-O., Lindahl, M., Porath, J. and Wadström, T. (1988) Purification and characterization of CS2, asialic acid-specific haemagglutinin of enterotoxigenic Escherichia coli. Biochem. J. 255, 105-111.
209. [209] Gonzalez, E.A. and Blanco, J. (1985) Comparitive study of inhibition of mannose-resistant haemagglutination caused by CFA/I, CFA/II, K88 and K99-positive Escherichia coli strains. FEMS Microbiol. Lett. 29, 115.
210. [210] Honda, T., Arita, M. and Miwatani, T. (1984) Characterization of new hydrophobia pili of human enterotoxigenic Escherichia coli: a possible new colonization factor. Infect. Immun. 43, 959-965.
211. [211] McConnell, M.M. and Rowe, B. (1989) Prevalence of the putative colonization factors CFA/III and PCFO166:H4 in enterotoxigenic Escherichia coli. J. Infect. Dis. 159, 582-586.
212. [212] Thomas, L.V., McConnell, M.M., Rowe, B. and Field, A.M. (1985) The possession of three novel coli surface antigens by enterotoxigenic Escherichia coli strains positive for the putative colonization factor PCF8775. J. Gen. Microbiol. 131, 2319-2326.
213. [213] Heuzenroeder, M.W., Neal, B.L., Thomas, C.J., Halter, R. and Manning, P.A. (1989) Characterization and molecular cloning of the PCF8775 CS5 antigene from an enterotoxigenic Escherichia coli O115:H40 isolated in central Australia. Mol. Microbiol. 3, 303-310.
214. [214] McConnell, M.M., Thomas, L.V., Willshaw, G.A., Smith, H.R. and Rowe, B. (1988) Genetic control and properties of coli surface antigens of colonization factor antigen IV (PCF8775) of enterotoxigenic Escherichia coli. Infect. Immun. 56, 1974-1980.
215. [215] Thomas, L.V., Rowe, B. and McConnell, M.M. (1987) in strains of Escherichia coli O167 a single plasmid encodes for the coli surface antigens CS5 and CS6 of putative colonization factor PCF8775, heat-stable enterotoxin, and colicin Ia. Infect. Immun. 55, 1336-1337.
216. [216] McConnell, M.M., Thomas, L.V., Scotland, S.M. and Rowe, B. (1986) The possession of coli surface antigen CS6 by enterotoxigenic Escherichia coli serogroups O25, O27, 0148 and 0159: a possible colonization factor? Curr. Microbiol. 14, 51-54.
217. [217] Thomas, L.V., Cravioto, A., Scotland, S.M. and Rowe, B. (1982) New fimbrial antigenic type (E8775) that may represent a colonization factor in enterotoxigenic Escherichia coli in humans. Infect. Immun. 35, 1119-1124.
218. [218] Deneke, C.F., McGowan, K., Larson, A.D. and Gorbach, S.L. (1984) Attachment of human and pig (K88) enterotoxigenic Escherichia coli strains to either human or porcine small intestinal cells. Infect. Immun. 45, 522-524.
219. [219] Deneke, C.F., Thorne, G.M. and Gorbach, S.L. (1979) Attachment pili from enterotoxigenic Escherichia coli pathogenic for humans. Infect. Immun. 26, 362-368.
220. [220] Hibberd, M.L., McConnell, M.M., Willshaw, G.A., Smith, H.R. and Rowe, B. (1991) Positive regulation of colonization factor antigen I (CFA/I) production by enterotoxigenic Escherichia coli producing colonization factors, Cs5, Cs6, Cs7, Cs17, PCFO9, PCFO159:H4 and PCFO166. J. Gen. Microbiol. 137, 1963-1970.
221. [221] Giampapa, C., Abraham, S., Chiang, T. and Beachey, E. (1988) Isolation and characterization of a receptor for type 1 fimbriae of Escherichia coli from pig enterocytes. J. Biol. Chem. 263, 5362-5367.
222. [222] Parkkinen, J. and Korhonen, T. (1989) Binding of plasminogen to Escherichia coli adhesion proteins. FEBS Lett. 250, 437-440.
223. [223] Sokurenko, E.V., Courtney, H.S., Abraham, S.N., Klemm, P. and Hasty, D.L. (1992) Functional heterogeneity of type 1 fimfriae of Escherichia coli. Infect. Immun. 60, 4709-4719.
224. [224] Klemm, P. (1985) Fimbrial adhesins of Escherichia coli. Rev. Infect. Dis. 7, 321-340.
225. [225] Kukkonen, M., Raunio, T., Vitkola, R., Lähteenmäki, K., Mäkelä, P.H., Klemm, P., Glegg, S. and Korhonen, T. (1993) Basement membrane carbohydrate as a target for bacterial adhesion: binding of type 1 fimbriae of Salmonella enterica and Escherichia coli to laminin. Mol. Microbiol. 7, 229-237.
226. [226] Leffler, H. and Svanborg-Edén, C. (1980) Chemical identification of a glycosphingolipid receptor for Escherichia coli attaching to human urinary tract epithelial cells and agglutinating human erythrocytes. FEMS Microbiol. Lett. 8, 127-134.
227. [227] Bock, K., Breimer, M.E., Brignole, A., Hansson, G.C., Karlsson, K.-A., Larson, G., Leffler, H., Samuelson, B.E., Strömberg, N., Svanborg-Edén, L. and Thurin, J. (1985) Specificity of binding of a strain of uropathogenic Escherichia coli to Gala1-4-containing glycosphingolipids. J. Biol. Chem. 260, 8545-8551.
228. [228] Morschhäuser, J., Hoschützky, H., Jann, K. and Hacker, J. (1990) Functional analysis of the sialic acid-binding adhesin SfaS of pathogenic Escherichia coli by site-specific mutagenesis. Infect. Immun. 58, 2133-2138.
229. [229] Parkkinen, J., Rogers, G.N., Korhonen, T.K., Dahr, W. and Finne, J. (1986) Identification of the O-linked sialyl oligosaccharides of glycophorin as the erythrocyte receptors for S-fimbriated Escherichia coli. Infect. Immun. 54, 37-42.
230. [230] Bilge, S.S., Clausen, C.R., Lau, W. and Moseley, S. (1989) Molecular characterization of afimbrial adhesin, F1845, mediating diffuse adherence of diarrhea-associated Escherichia coli to Hep-2 cells. J. Bacteriol. 171, 4281-4289.
231. [231] Kerneis, S., Bilge, S.S., Fourel, V., Chauviere, G., Coconnier, M.H. and Servin, A.L. (1991) Use of purified F1845 fimbrial adhesin to study localization and expression of receptors for diffusely adhering Escherichia coli during enterocytic differentiation of human colon carcinoma cell lines HT-29 and Caco-2 in culture. Infect. Immun. 59, 4013-4018.
232. [232] Pere, A., Leinonen, M., Väisänen-Rhen, V., Rhen, M. and Korhonen, T.K. (1985) Occurrence of type 1C fimbriae on Escherichia coli strains isolated from human extraintestinal infections. J. Gen. Microbiol. 131, 1705-1711.
233. [233] Jalajakumari, M.B., Thomas, C.J., Halter, R. and Mannings, P.A. (1989) Genes for biosynthesis and assembly of CS3 pili of CFA/II enterotoxigenic Escherichia coli: novel regulation of pilus production by bypassing an amber codon. Mol. Microbiol. 3, 1685-1695.
234. [234] Savarino, S.J., Fox, P., Yikang, D. and Nataro, J.P. (1994) Identification and characterization of a gene cluster mediating enteroaggregative Escherichia coli aggregative adherence fimbria I biogenesis. J. Bacteriol. 176, 4949-4957.
235. [235] Klemm, P. (1992) FimC, a chaperone-like periplasmic protein of Escherichia coli involved in biogenesis of type 1 fimbriae. Res. Microbiol. 143, 831-838.
236. [236] Schmoll, T., Morschhäuser, J., Ott, M., Lydwig, B., Van Die, I. and Hacker, J. (1990) Complete genetic organization and functional aspects of the Escherichia coli S fimbrial adhesin determinant: nucleotide sequence of the genes sfa B, C, D, E, F. Microb. Pathog. 9, 331-343.
237. [237] Schmoll, T., Hacker, J. and Goebel, W. (1987) Nucleotide sequence of the sfaA gene coding for the S fimbrial protein subunit of Escherichia coli. FEMS Microbiol. Lett. 41, 229-235.
238. [238] Raina, S., Missiakas, D., Baird, L., Kumar, S. and Georgopoulos, C. (1993) Identification and transcriptional analysis of the Escherichia coli htrE operon which is homologous to pap and related pilin operons. J. Bacteriol. 175, 5009-5021.
239. [239] Mol, O., Oud, R.P.C., De Graaf, F.K. and Oudega, B. (1995) The Escherichia coli K88 periplasmic chaperon FaeE forms a heterotrimeric complex with the minor fimbrial component FaeH and with the minor fimbrial component Fael. Microb. Path. 18, 115-128.