Differential regulation of the HIV-1 LTR by specific NF-κB subunits in HSV-1-infected cells

Virology

Volumn 224, Issue 1, 1996, Pages 214-223

  Schafer, Susan L ^a   Hiscott, John ^b   Pitha, Paula M ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HERPES SIMPLEX VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROVIRUS; TRANSCRIPTION REGULATION; VIRUS REPLICATION;

ANIMALIA; HERPES; HERPESVIRIDAE; HUMAN HERPESVIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030273622     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0523     Document Type: Article

References (56)

1. Baeuerle, P. A., and Baltimore, D. (1988). IκB: A specific inhibitor of the NF-κB transcription factor. Science 242, 540-546.
2. Barroga, C. F., Stevenson, J. K., Schwarz, E. M., and Verma, I. M. (1995). Constitutive phosphorylation of IκBα by casein kinase II. Proc. Natl. Acad. Sci. USA 92, 7637-7641.
3. Beg, A., and Baldwin, A. S. (1993). The IκB proteins: Regulators of Rel/NF-κB transcription factors. Genes Dev. 7, 2064-2070.
4. Beg, A., Finco, T. S., Nantermet, P. V., and Baldwin, A. S., Jr. (1993). Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα activation. Mol. Cell. Biol. 13, 3301-3310.
5. Bitar, R., Beauparlant, P., Lin, R., Pitha, P., and Hiscott, J. (1995). Retrovirus-mediated transfer of nuclear factor-κB subunit genes modulates IκBα and interferon β expression. Cell Growth Differ. 6, 965-976.
6. Blank, V., Kourilsky, P., and Israel, A. (1991). Cytoplasmic retention, DNA binding and processing of the NF-κB p50 precursor are controlled by a small region in its C-terminus. EMBO J. 10, 4159-4167.
7. Brown, K., Park, S., Kanno, T., Franzosos, B., and Siebenlist, U. (1993). Mutual regulation of the transcriptional activator NF-κB and its inhibitor IκBα. Proc. Natl. Acad. Sci. USA 90, 2532-2536.
8. Brownwell, E., Mittereder, N., and Rice, N. R. (1989). A human rcl proto-oncogene cDNA containing an Alu fragment as a potential coding exon. Oncogene 4, 935-942.
9. Bull, P., Morley, K. L., Hockstra, M. F., Hunter, T., and Verman, I. M. (1990). The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Mol. Cell. Biol. 10, 5473-5485.
10. Garoufalis, E., Kwan, I., Lin, R., Mustafa, A., Pepin, N., Roulston, A., Lacoste, J., and Hiscott, J. (1994). Viral induction of the human interferon β promoter: Modulation of transcription by NF-κB/rel proteins and interferon regulatory factors. J. Virol. 68, 4707-4715.
11. Ghosh, S., and Baltimore, D. (1990). Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature 344, 678-682.
12. Ghosh, S., Gilfford, A. M., Riviere, L. R., Tempst, P., Nolan, G. P., and Baltimore, D. (1990). Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal. Cell 62, 1019-1029.
13. Gilmore, T. D. (1990). NF-κB, KBF1, dorsal, and related matters. Cell 62, 841-843.
14. Golden, M. P., Kim, S., Hammer, S. M., Ladd, E. A., Schaffer, P. A., Deluca, N., Albrecht, M. A. (1992). Activation of human immunodeficiency virus by herpes simplex virus. J. Infect. Dis. 166, 494-499.
15. Hammarskjold, M.-L., and Simurda, M. C. (1992). Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF-κB activity. J. Virol. 66, 6496-6501.
16. Hansen, S., Nerlov, C., Zabel, U., Verde, P., Johser, M., Bauerle, P., and Blasi, F. (1992). A novel complex between the p65 subunit of NF-κB and c-rel binds J to a DNA element involved in phorbol ester induction the human urokinase. EMBO J. 11, 205-213.
17. Haskill, S., Beg, A. A., Tompkins, S. M., Morris, J. S., Yurachko, A. B., Sampson-Johannes, I., Mandal, K., Ralph, P., and Baldwin, A. S., Jr. (1991). Characterization of an immediate-early gene induced inadherent monocyte that encode IκB-like activity. Cell 65, 1281-1289.
18. Henkel, T., Zabel, U., vanZee, K., Muller, J. M., Fanning, E., and Bauerle, P. (1992). Intramolecular masking of the nuclear localization in signal and dinerization domain in the precursor for the p50 NF-κB subunit. Cell 68, 1121-1133.
19. Inoue, J.-I., Kerri, L., Kakizuka, A., and Verma, I. M. (1992). IκBγ, a 70 kd protein identical to the c-terminal half of p110 NF-κB: A new member of the IκB family. Cell 68, 1109-1120.
20. Inoue, J.-I., Lawrence, K. D., Ransone, L. J., Bengal, E., Huntert, T., and Verman, N. M. (1991). c-rel activated but v-rel suppresses transcription from κB sites. Natl. Proc. Acad. Sci. USA 88, 3715-3719.
21. Ip, T. Y., Reach, M., Engstrom, Y., Kadalayil, L., Cai, H., Gonzalz-Crespo, S., Tatei, K., and Levine, M. (1993). Dif, a dorsal-related gene that mediated an immune response in Drosophila. Cell 75, 753-763.
22. Kang, S. M., Tran, H. C., Grilli, M., Lenardo, M. J. (1992). NF-κB subunit regulation in non-transformed CD4+ T lymphocytes. Science 256, 1452-1456.
23. Kerr, L. P., Duckett, C. S., Wansley, P., Zhang, G., Chiao, P., Nabel, G., McKeithan, T. W., Bauerle, P. A., and Verma, I. M. (1992). The proto-oncogene BCL-3 encodes an IκB protein. Genes Dev. 6, 2352-2363.
24. Kieran, M., Blank, V., Logeat, F., Vandekerckhove, J., Lottspeich, F., Le Bail, O., Urban, M. B., Kourilsky, P., Baeuerle, P. A., and Israel, A. (1990). The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product. Cell 62, 1007-1018.
25. Kowalik, T. F., Wing, B., Haskill, J. S., Azizkhan, J. C., Baldwin, A. S., Jr., and Huang, E.-S. (1993). Multiple mechanisms are implicated in the regulation of NF-κB activity during human cytomegalovirus infection. Proc. Natl. Acad. Sci. USA 90, 1107-1111.
26. Kumar, A., Haque, J., Lacoste, J., Hiscott, J., and Williams, B. (1994). Double stranded RNA-dependent protein kinase activates transcription factory NF-κB by phosphorylating IκB. Proc. Natl. Acad. Sci. USA 91, 6288-6292.
27. Kunsch, C., Ruber, S. M., and Rosen, C. A. (1992). Selection of optimal κB/Rel DNA binding motifs: Interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Mol. Cell. Biol. 12, 4412-4421.
28. Lin, R., Beauparlant, P., Makris, C., Meloche, S., and Hiscott, J. (1996). Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsinic protein stability. Mol. Cell. Biol., 16, 1401-1409.
29. Liou, H. C., and Baltimore, D. (1993). Regulation of NF-κB/rel transcription factor and IκB inhibitor system. Curr. Opin. Cell Biol. 5, 477-487.
30. Liou, H. C., Nolan, G. P., Ghosh, S., Fujita, T., and Baltimore, D. (1992). The NF-κB, p50 precursor, p105, contains an internal IκB-like inhibitor that preferentially inhibits p50. EMBO J. 11, 3003-3009.
31. Maran, A., Maitra, R. K., Kumar, A., Dong, B., Xiao, W., Li, G., Williams, B. R. G., Torrence, P. F., and Silverman, R. H. (1994). Blockage of NFκB signaling by selective ablation of an mRNA target by 2-5A antisense chimeras. Science 265, 789-792.
32. Margolis, D. M., Ostrove, J. M., and Straus, S. E. (1993). HSV-1 activation of HIV-1 transcription is augumented by a cellular protein that binds near the initiator element. Virology 192, 370-374.
33. Matthews, J. R., Watson, E., Buckley, S., and Hay, R. T. (1993). Interaction of C-terminal of p105 with the nuclear localization signal of p50 is required for inhibition of NF-κB DNA binding action. Nucleic Acids Res. 21, 4516-4523.
34. Mercurio, F., DiDonatio, J. A., Rosetti, C., and Karin, M. (1993). p105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction. Genes Dev. 7, 705-718.
35. Mosca, J. D., Bednarik, D. P., Raj, N. B. K., Rosen, C. A., Sodroski, J. G., Haseltine, W. A., and Pitha, P. M. (1987a). Herpes simplex virus type-1 can reactivate transcription of latent human immunodeficiency virus. Nature 325, 67-70.
36. Mosca, J. D., Bednarik, D. P., Raj, N. B. K., Rosen, C. A., Sodroski, J. G., Haseltine, W. A., Hayward, G. S., and Pitha, P. M. (1987b). Activation of human immunodeficiency virus by herpesvirus infection: Identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1. Proc. Natl. Acad. Sci. USA 84, 7408-7412.
37. Naumann, M., and Scheidereit, C. (1994). Activation of NF-κB in vivo is regulated by multiple phosphorylation. EMBO J. 13, 4597-4607.
38. Nolan, G. P., Fujita, T., Bhatia, K., Hoppi, C., Liou, H.-C., Scott, M. L., and Baltimore, D. (1993). The Bcl-3 proto-oncogene encodes a nuclear IκB-like molecule that preferentially interacts with NF-κB p50 and p52 in a phosphorylation dependent manner. Mol. Cell. Biol. 13, 3557-3566.
39. Oeth, P. A., Parry, G. C. N., Kunsch, C., Nantermet, P., Rosen, C. A., and Mackman, N. (1994). Lipopolysaccharide induction of tissue factor gene expression in monocytic cells is mediated by binding of c-Rel/p65 heterodimers to a κB-like site. Mol. Cell. Biol. 14, 3772-3781.
40. Pahl, H. L., and Baeuerle, P. A. (1995). A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-κB. EMBO J. 14, 2580-2588.
41. Popik, W., and Pitha, P. M. (1994). Differential effect of tumor necrosis factor-α and herpes simplex virus type 1 replication. Virology 202, 521-529.
42. Raj, N. B. K., Au, W.-C., and Pitha, P. M. (1991). Identification of a novel virus-responsive sequence in the promoter of murine interferon-α genes. J. Biol. Chem. 266, 11360-11365.
43. Raj, N. B. K., and Pitha, P. M. (1981). Analysis of interferon message RNA in human fibroblast cells induced to produce interferon. Proc. Natl. Acad. Sci. USA 78, 7426-7430.
44. Rice, N. R., Mackichan, M. L., and Israel, A. (1992). The precursors of NF-κB has IκB-like functions. Cell 71, 243-251.
45. Richardson, P. M., and Gilmore, T. D. (1991). vRel is an inactive member of the rel family of transcriptional activating proteins. J. Virol. 65, 3122-3130.
46. Rosen, C. A., Sodroski, J. G., and Haseltine, W. A. (1985). The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat. Cell 41, 813-823.
47. Sambucetti, L. C., Cherrington, J. M., Wilkinson, G. W. G., and Mocarski, E. S. (1989). NF-κB activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation. EMBO J. 13, 4251-4258.
48. Scheinman, R. I., Bes, A. A., and Baldwin, A. S. (1993). NF-κB p100 (Lyt-10) is a component of H2TFI and cofunction as an IκB-like molecule. Mol. Cell. Biol. 13, 6089-6101.
49. Sun, S.-C., Ganchi, P. A., Ballard, D. W., and Greene, W. C. (1993). NF-κB controls expression of inhibitor IκBα: Evidence for an inducible autoregulatory pathway. Science 259, 1912-1915.
50. Tan, T.-H., Huang, G. P., Sica, A., Ghosh, P., Young, H. A., Longo, D. L., and Rice, N. R. (1992). κB site-dependent activation of the interleukin-2 receptor α-chain gene promoter by human c-Rel. Mol. Cell. Biol. 12, 4067-4075.
51. Thanos, D., and Maniatis, T. (1995). Identification of the rel family members required for virus induction of the human beta interferon gene. Mol. Cell. Biol. 13, 152-164.
52. Thompson, J. E., Phillips, R. J., Erdjument-Bromage, H., Tempsts, P., and Ghosh, S. (1995). IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80, 573-582.
53. Urban, M., and Baeuerle, P. (1991). The role of the p50 and p65 subunits of NF-κB in the recognition of cognate sequences. New Biol. 3, 279-288.
54. Vlach, J., and Pitha, P. M. (1992). Herpes simplex virus type 1-mediated induction of human immunodeficiency virus type 11 provirus correlates with binding of nuclear proteins to the NF-κB enhancer and leader sequence. J. Virol. 66, 3616-3623.
55. Vlach, J., and Pitha, P. M. (1993). Differential contribution of herpes simplex virus type-1 gene products and cellular factors to the activation of human immunodeficiency virus type-1 provirus. J. Virol. 67, 4427-4431.
56. Zabel, U., and Baeuerle, P. A. (1990). Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA. Cell 61, 255-265.