The synthesis and characterization of analogs of the antimicrobial compound squalamine: 6β-hydroxy-3-aminosterols synthesized from hyodeoxycholic acid

Steroids

Volumn 61, Issue 10, 1996, Pages 565-571

  Jones, Stephen R ^a   Kinney, William A ^b   Zhang, Xuehai ^b   Jones, Lisa M ^b   Selinsky, Barry S ^a  

^a VILLANOVA UNIVERSITY   (United States)

^b Genaera Corporation   (United States)

Author keywords

aminosterol; antimicrobials; hyodeoxycholic acid; squalamine; synthesis

Indexed keywords

ANTIINFECTIVE AGENT; CARBOXYLIC ACID; HYODEOXYCHOLIC ACID; KETONE; POLYAMINE; SQUALAMINE DERIVATIVE; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

AMINATION; ANTIMICROBIAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; ESTERIFICATION; ISOMERISM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATION; PSEUDOMONAS AERUGINOSA; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

CANDIDA ALBICANS; ESCHERICHIA COLI; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0030273195     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(96)00114-6     Document Type: Article

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